B9.2· 68 questions · 68 marks · 82 min · 2005–2024· Multiple choice
Every Cambridge IGCSE Science - Combined Paper 1 question on heart, laid out as 25 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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25 / 25Answers below. Sit the paper first if you are practising.
Pastlit
Science - Combined 0653 · Heart — Paper 1
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
Pastlit
Science - Combined 0653 · Heart — Paper 1
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
| Question | Answer | Marks | From |
|---|---|---|---|
| 1 | C | 1 | 0653/11 Oct/Nov 2005 |
| 2 | D | 1 | 0653/11 May/June 2006 |
| 3 | D | 1 | 0653/11 Oct/Nov 2006 |
| 4 | D | 1 | 0653/11 May/June 2007 |
| 5 | C | 1 | 0653/11 Oct/Nov 2007 |
| 6 | B | 1 | 0653/11 May/June 2008 |
| 7 | D | 1 | 0653/11 Oct/Nov 2008 |
| 8 | D | 1 | 0653/11 May/June 2009 |
| 9 | A | 1 | 0653/11 Oct/Nov 2010 |
| 10 | A | 1 | 0653/12 Oct/Nov 2010 |
| 11 | A | 1 | 0653/13 Oct/Nov 2010 |
| 12 | C | 1 | 0653/11 May/June 2011 |
| 13 | C | 1 | 0653/12 May/June 2011 |
| 14 | C | 1 | 0653/11 Oct/Nov 2011 |
| 15 | see sheet | 1 | 0653/11 May/June 2012 |
| 16 | see sheet | 1 | 0653/11 May/June 2012 |
| 17 | C | 1 | 0653/12 May/June 2012 |
| 18 | C | 1 | 0653/12 May/June 2012 |
| 19 | C | 1 | 0653/13 May/June 2012 |
| 20 | A | 1 | 0653/12 May/June 2013 |
| 21 | C | 1 | 0653/13 May/June 2013 |
| 22 | C | 1 | 0653/11 Oct/Nov 2013 |
| 23 | C | 1 | 0653/12 Oct/Nov 2013 |
| 24 | D | 1 | 0653/13 Oct/Nov 2013 |
| 25 | A | 1 | 0653/11 May/June 2014 |
| 26 | B | 1 | 0653/11 May/June 2014 |
| 27 | A | 1 | 0653/12 May/June 2014 |
| 28 | A | 1 | 0653/13 May/June 2014 |
| 29 | B | 1 | 0653/13 May/June 2014 |
| 30 | C | 1 | 0653/11 May/June 2015 |
| 31 | B | 1 | 0653/13 May/June 2015 |
| 32 | D | 1 | 0653/11 Oct/Nov 2015 |
| 33 | A | 1 | 0653/12 Oct/Nov 2015 |
| 34 | D | 1 | 0653/12 Oct/Nov 2015 |
| 35 | D | 1 | 0653/11 May/June 2016 |
| 36 | D | 1 | 0653/12 May/June 2016 |
| 37 | D | 1 | 0653/13 May/June 2016 |
| 38 | D | 1 | 0653/13 Oct/Nov 2016 |
| 39 | C | 1 | 0653/12 Feb/March 2017 |
| 40 | C | 1 | 0653/11 May/June 2017 |
| 41 | C | 1 | 0653/12 May/June 2017 |
| 42 | C | 1 | 0653/13 May/June 2017 |
| 43 | D | 1 | 0653/12 Oct/Nov 2017 |
| 44 | A | 1 | 0653/13 Oct/Nov 2017 |
| 45 | A | 1 | 0653/12 Feb/March 2018 |
| 46 | B | 1 | 0653/11 May/June 2018 |
| 47 | B | 1 | 0653/12 May/June 2018 |
| 48 | B | 1 | 0653/13 May/June 2018 |
| 49 | D | 1 | 0653/11 Oct/Nov 2018 |
| 50 | D | 1 | 0653/12 Feb/March 2019 |
| 51 | D | 1 | 0653/13 May/June 2019 |
| 52 | A | 1 | 0653/11 Oct/Nov 2019 |
| 53 | D | 1 | 0653/11 Oct/Nov 2019 |
| 54 | B | 1 | 0653/12 Oct/Nov 2019 |
| 55 | B | 1 | 0653/13 Oct/Nov 2019 |
| 56 | D | 1 | 0653/11 May/June 2020 |
| 57 | B | 1 | 0653/12 Oct/Nov 2020 |
| 58 | D | 1 | 0653/12 Feb/March 2021 |
| 59 | C | 1 | 0653/11 Oct/Nov 2021 |
| 60 | D | 1 | 0653/12 Feb/March 2022 |
| 61 | A | 1 | 0653/13 May/June 2022 |
| 62 | D | 1 | 0653/11 Oct/Nov 2022 |
| 63 | B | 1 | 0653/11 May/June 2023 |
| 64 | B | 1 | 0653/13 May/June 2023 |
| 65 | D | 1 | 0653/11 May/June 2024 |
| 66 | D | 1 | 0653/12 May/June 2024 |
| 67 | D | 1 | 0653/11 Oct/Nov 2024 |
| 68 | D | 1 | 0653/13 Oct/Nov 2024 |
7 The diagram shows a section through a human heart. 5 1 4 8 2 6 right left side side 3 7 In which order does oxygenated blood pass through the heart? A 1 → 2 → 3 → 4 B 4 → 3 → 2 → 1 C 5 → 6 → 7 → 8 D 8 → 7 → 6 → 5
1 marks
Answer: C
6 The diagram shows an external view of the heart of a man who has recently had a heart attack. Which blood vessel was blocked by a blood clot to cause the attack? B aorta C A D area of dead muscle
1 marks
Answer: D
6 The diagram shows a section through the human heart. Which vessel is a vein containing oxygenated blood? B C A D
1 marks
Answer: D
7 The diagram shows an external view of the human heart. 2 3 4 1 5 Which vessels contain oxygenated blood? A 1, 2 and 4 B 1, 3 and 4 C 2, 3 and 5 D 3, 4 and 5
1 marks
Answer: D
8 The diagram shows a section through the heart. 2 3 4 1 The ventricles contract and blood is forced into the arteries. What is the state of valve 3 and 4 when this happens? valve 3 valve 4 A closed closed B closed open C open closed D open open
1 marks
Answer: C
6 The blockage of which blood vessel causes a heart attack? A aorta B coronary artery C pulmonary artery D pulmonary vein
1 marks
Answer: B
7 The diagram shows a section through the human heart. tendons Which structures are joined by the tendons? A atrium wall and septum B atrium wall and valve C septum and ventricle wall D valve and ventricle wall
1 marks
Answer: D
4 The diagram shows only the left side of the heart as it appears at one particular stage in a heart-beat. Which statements describe the left side of the heart at this stage? 1 The semilunar valve is closed. 2 Deoxygenated blood is being pumped to the lungs. 3 Oxygenated blood is entering the atrium. 4 The bicuspid valve is closed. A 1 and 2 B 1 and 3 C 2 and 4 D 3 and 4
1 marks
Answer: D
7 Which blood vessel carries oxygenated blood away from the heart? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: A
8 Which blood vessel carries oxygenated blood away from the heart? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: A
5 Which blood vessel carries oxygenated blood away from the heart? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: A
6 The diagram shows the human heart in section. Which chamber of the heart pumps blood the greatest distance? A B D C
1 marks
Answer: C
6 The diagram shows the human heart in section. Which chamber of the heart pumps blood the greatest distance? A B D C
1 marks
Answer: C
6 Oxygenated blood returns to the heart from the lungs in vessel X and leaves the heart to circulate around the body in vessel Y. What are X and Y? X Y A aorta pulmonary vein B pulmonary artery vena cava C pulmonary vein aorta D vena cava pulmonary artery
1 marks
Answer: C
7 Through which vessel does oxygenated blood enter the heart? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
9 The graphs show changes in the rate of heartbeat and in the concentration of sugar in the blood over the same period of time. When was adrenaline secreted? concentration of sugar in blood / arbitrary units time heart rate / arbitrary units time A B C D
1 marks
7 Which sequence of numbers represents the path taken by a deoxygenated red blood cell? lungs 1 right atrium left atrium 2 4 3 5 right ventricle left ventricle 6 body tissues A 1 → 3 → 2 → 6 B 1 → 4 → 5 → 6 C 6 → 2 → 3 → 1 D 6 → 5 → 4 → 1
1 marks
Answer: C
9 The graphs show changes in the rate of heartbeat and in the concentration of sugar in the blood over the same period of time. When was adrenaline secreted? concentration of sugar in blood / arbitrary units time heart rate / arbitrary units time A B C D
1 marks
Answer: C
7 Which sequence of numbers represents the path taken by a deoxygenated red blood cell? lungs 1 right atrium left atrium 2 4 3 5 right ventricle left ventricle 6 body tissues A 1 → 3 → 2 → 6 B 1 → 4 → 5 → 6 C 6 → 2 → 3 → 1 D 6 → 5 → 4 → 1
1 marks
Answer: C
7 What is the function of the valves in the heart? A to prevent blood from flowing backwards B to pump blood through the heart C to separate blood cells from plasma D to separate oxygenated and deoxygenated blood
1 marks
Answer: A
9 The diagram shows a section through the heart. valve X left ventricle Which events occur as the left ventricle contracts? A atrial wall contracts and valve X closes B atrial wall contracts and valve X opens C atrial wall relaxes and valve X closes D atrial wall relaxes and valve X opens
1 marks
Answer: C
7 The diagram shows a section through the human heart. Which structure is the tricuspid valve? D A C B
1 marks
Answer: C
7 The diagram shows a section through the human heart. Which structure is the tricuspid valve? D A C B
1 marks
Answer: C
7 Which chambers of the heart have the thickest and most muscular walls? A left atrium and right atrium B left atrium and right ventricle C left ventricle and right atrium D left ventricle and right ventricle
1 marks
Answer: D
5 The diagram shows a section through the human heart. The four heart valves are labelled P, Q, R and S. Which valves are open when the atria contract? key v¥ =valve open X =valve closed \N \ €® KL \ &®& \ &€® 1D x << *& <1O 0 0O WwW > ~~ * QL NID
1 marks
Answer: A
9 Which situation is most likely to cause an increase in the secretion of adrenaline? A A person eats a meal rich in glucose. B A person is awoken suddenly by thunder and lightning. C A person’s blood glucose level decreases because they have not eaten. D A person’s pulse rate falls while they are asleep.
1 marks
Answer: B
6 The diagram shows a section through the heart. The atria and ventricles are numbered. 1 2 4 3 What is the sequence in which the atria and ventricles contract during one heart beat? A 1 and 2 together, 3 and 4 together B 1 and 4 together, 2 and 3 together C 1, 2, 3, 4 D 1, 3, 2, 4
1 marks
Answer: A
6 The diagram shows a section through the human heart. The four heart valves are labelled P, Q, R and S. Which valves are open when the atria contract? key v¥ =valve open X =valve closed \N \ €® KL \ &®& \ &€® 1D x << *& <1O 0 0O WwW > ~~ * QL NID
1 marks
Answer: A
9 Which situation is most likely to cause an increase in the secretion of adrenaline? A A person eats a meal rich in glucose. B A person is awoken suddenly by thunder and lightning. C A person’s blood glucose level decreases because they have not eaten. D A person’s pulse rate falls while they are asleep.
1 marks
Answer: B
8 The diagram shows a heart in section and some of its blood vessels. Q R What are the parts Q and R? Q R A aorta septum B aorta vena cava C atrium septum D atrium vena cava
1 marks
Answer: C
7 The diagram represents the human heart and associated blood vessels. Which blood vessel carries deoxygenated blood away from the heart? B C D A
1 marks
Answer: B
10 Which row is correct for the hormone adrenaline? effect on blood organ where effect on the glucose adrenaline is pulse rate concentration destroyed A lowered decreased kidney B lowered decreased liver C raised increased kidney D raised increased liver
1 marks
Answer: D
6 The diagram shows a section through the heart. To ensure that blood will flow to the lungs, which valve must be closed? B C A D
1 marks
Answer: A
10 When an athlete prepares for the start of a sprint race, excitement causes the concentration of a hormone in the blood to increase. What effects does the hormone have on the blood glucose concentration and the heart rate of the athlete? blood glucose heart rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
6 The diagram shows a section through the human heart. tendons Which structures are joined by the tendons? A atrium wall and septum B atrium wall and valve C septum and ventricle wall D valve and ventricle wall
1 marks
Answer: D
7 The diagram shows a section through the human heart. tendons Which structures are joined by the tendons? A atrium wall and septum B atrium wall and valve C septum and ventricle wall D valve and ventricle wall
1 marks
Answer: D
6 The diagram shows a section through the human heart. tendons Which structures are joined by the tendons? A atrium wall and septum B atrium wall and valve C septum and ventricle wall D valve and ventricle wall
1 marks
Answer: D
9 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
7 Oxygenated blood returns to the heart from the lungs in vessel X and leaves the heart to circulate around the body in vessel Y. What are X and Y? X Y A aorta pulmonary vein B pulmonary artery vena cava C pulmonary vein aorta D vena cava pulmonary artery
1 marks
Answer: C
7 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open
1 marks
Answer: C
7 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open
1 marks
Answer: C
7 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open
1 marks
Answer: C
10 Which changes occur in an athlete just before the start of a race? adrenaline glucose in pulse rate in the blood the blood A decreases decreases increases B decreases increases decreases C increases decreases decreases D increases increases increases
1 marks
Answer: D
7 The diagram shows a section through the human heart. Which is the septum? C D B A
1 marks
Answer: A
8 The diagram shows the human heart and the main blood vessels associated with it. Which blood vessel is the pulmonary artery? A B C D
1 marks
Answer: A
7 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open
1 marks
Answer: B
7 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open
1 marks
Answer: B
7 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open
1 marks
Answer: B
7 The diagram shows a section through the heart. Which labelled part has the correct function stated? D the artery taking deoxygenated blood A to the lungs the valve which stops deoxygenated blood flowing backwards C B the heart chamber which receives blood the valve between from the left atrium the atrium and the ventricle
1 marks
Answer: D
8 The diagram shows a section through the human heart. Which vessel is a vein containing oxygenated blood? B C A D
1 marks
Answer: D
5 The diagram shows a section through the heart. 2 3 1 4 Which labels show the two ventricles in the heart? A 1 and 2 B 2 and 3 C 3 and 4 D 4 and 1
1 marks
Answer: D
6 Which blood vessel carries blood from the heart to the body? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: A
9 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
5 Which statements about the site of valves are correct? 1 present between atria and ventricles 2 present between ventricles and arteries 3 present between arteries and lungs A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
1 marks
Answer: B
5 Which statements about the site of valves are correct? 1 present between atria and ventricles 2 present between ventricles and arteries 3 present between arteries and lungs A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
1 marks
Answer: B
9 Four people have the same resting pulse rate and the same blood glucose concentration. The table shows their pulse rates and blood glucose concentrations later on the same day. Which person has the highest concentration of adrenaline in their blood? blood glucose pulse rate / beats concentration per minute /mg per dm3 A 70 65 B 70 100 C 120 65 D 120 100
1 marks
Answer: D
9 Which blood vessel carries blood from the heart to the lungs? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: B
10 The table shows some data recorded by a scientist about a student. pulse rate pupil size in eye / beats per minute 68 The scientist then frightens the student with a sudden loud noise. Which row shows the results immediately after the loud noise? pulse rate pupil size in eye / beats per minute A 60 B 80 C 60 D 80
1 marks
Answer: D
6 Which vessel does oxygenated blood enter the heart through? A aorta B pulmonary artery C pulmonary vein D vena cava
1 marks
Answer: C
9 A student encounters a large growling dog. The student is frightened and prepares to run. What is likely to occur? heart rate pupil diameter A unchanged narrows B unchanged widens C increases narrows D increases widens
1 marks
Answer: D
7 The diagram shows a cross-section of a human heart. 4 1 2 3 Which numbers correctly identify the parts of the heart? muscular wall septum left ventricle A 1 4 2 B 1 4 3 C 4 1 2 D 4 1 3
1 marks
Answer: A
9 Adrenaline is secreted during ‘fight or flight’ situations. Which combination of effects does adrenaline cause? A decreased breathing rate and wider pupils B decreased pulse rate and narrower pupils C increased breathing rate and decreased pulse rate D increased pulse rate and wider pupils
1 marks
Answer: D
7 The diagram shows a section through the heart. Which vessel is the pulmonary vein? D A B C
1 marks
Answer: B
7 From which chamber does the blood leave the heart to travel to the organs of the body? D A B C
1 marks
Answer: B
10 The table shows some data about a student. pulse rate pupil size in eye / beats per minute 68 The student is frightened by a sudden loud noise. Which row shows the results immediately after the loud noise? pulse rate pupil size in eye / beats per minute A 60 B 80 C 60 D 80
1 marks
Answer: D
10 A cat suddenly jumps in front of a person walking down a street. The person is shocked. Which row shows the changes that occur? adrenaline level pulse rate A unchanged decreases B unchanged increases C increases decreases D increases increases
1 marks
Answer: D
9 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 Which row shows effects of increased adrenaline secretion on the body? breathing rate size of pupils A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D