Heart — Paper 2 · IGCSE Science - Combined 0653

6 Oxygenated blood returns to the heart from the lungs in vessel X and leaves the heart to circulate around the body in vessel Y. What are X and Y? X Y A aorta pulmonary vein B pulmonary artery vena cava C pulmonary vein aorta D vena cava pulmonary artery

1 marks

Answer: C

This question in 0653/22 Feb/March 2017

7 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open

1 marks

Answer: C

This question in 0653/21 May/June 2017

6 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open

1 marks

Answer: C

This question in 0653/22 May/June 2017

7 The diagram shows a section through the heart. 1 2 The ventricles contract and blood is forced into the arteries. What is the state of valves 1 and 2 when this happens? valve 1 valve 2 A closed closed B closed open C open closed D open open

1 marks

Answer: C

This question in 0653/23 May/June 2017

8 The diagram shows the double circulation of blood around the human body. Which blood vessel contains blood at the highest pressure? lungs A B C D body

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2017

6 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open

1 marks

Answer: B

This question in 0653/21 May/June 2018

4 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open

1 marks

Answer: B

This question in 0653/22 May/June 2018

6 The diagram shows a section through the human heart. valve 4 valve 3 valve 2 valve 1 What happens to the valves as blood is being pumped to the lungs? valve 1 valve 2 valve 3 valve 4 A closed closed open closed B closed closed open open C open open closed closed D open open closed open

1 marks

Answer: B

This question in 0653/23 May/June 2018

10 Which statement about adrenaline is not correct? A Adrenaline is transported in the blood plasma. B Adrenaline lowers the blood glucose concentration. C The heart is one of the target organs for adrenaline. D The liver destroys adrenaline.

1 marks

Answer: B

This question in 0653/21 Oct/Nov 2018

7 The diagram shows the external surface of the heart. Which letter identifies a coronary artery? A B C D

1 marks

Answer: D

This question in 0653/22 Oct/Nov 2018

8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/21 May/June 2019

8 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2019

5 The diagram represents the human heart and four blood vessels. Which blood vessel contains blood at the highest pressure? B C D A

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2019

8 Four people have the same resting pulse rate and the same blood glucose concentration. The table shows their pulse rates and blood glucose concentrations later on the same day. Which person has the highest concentration of adrenaline in their blood? blood glucose pulse rate / beats concentration per minute /mg per dm3 A 70 65 B 70 100 C 120 65 D 120 100

1 marks

Answer: D

This question in 0653/21 May/June 2020

9 Four people have the same resting pulse rate and the same blood glucose concentration. The table shows their pulse rates and blood glucose concentrations later on the same day. Which person has the highest concentration of adrenaline in their blood? blood glucose pulse rate / beats concentration per minute /mg per dm3 A 70 65 B 70 100 C 120 65 D 120 100

1 marks

Answer: D

This question in 0653/22 May/June 2020

10 The table shows some data recorded by a scientist about a student. pulse rate pupil size in eye / beats per minute 68 The scientist then frightens the student with a sudden loud noise. Which row shows the results immediately after the loud noise? pulse rate pupil size in eye / beats per minute A 60 B 80 C 60 D 80

1 marks

Answer: D

This question in 0653/22 Feb/March 2021

6 The diagram shows the circulation of blood through the heart, lungs and other organs. lungs 4 1 3 heart 2 other organs Which row gives a correct comparison of oxygen concentration in the blood in two of the numbered vessels? lower oxygen higher oxygen concentration concentration A 1 2 B 1 3 C 3 4 D 4 2

1 marks

Answer: D

This question in 0653/21 May/June 2022

7 Which structures in the circulatory system ensure the one-way flow of blood? A arteries B atria C valves D ventricles

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2022

8 Adrenaline is produced by the adrenal glands in times of … 1 … . It targets vital organs, increases … 2 … which increases the delivery of oxygen and … 3 … to the brain and muscles, preparing the body for 'flight or fight'. Which words complete gaps 1, 2 and 3? 1 2 3 A stress heart rate glucose B stress breathing rate glycogen C relaxation breathing rate glucose D relaxation heart rate glycogen

1 marks

Answer: A

This question in 0653/22 Feb/March 2023

8 The diagram shows a section through the heart. Which vessel is the pulmonary vein? D A B C

1 marks

Answer: B

This question in 0653/21 May/June 2023

7 From which chamber does the blood leave the heart to travel to the organs of the body? D A B C

1 marks

Answer: B

This question in 0653/23 May/June 2023

7 The diagram shows a section through the heart. X What causes valve X to close? A contraction of the left ventricle B contraction of the left atrium C relaxation of the left ventricle D relaxation of the left atrium

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2023

8 A diagram of the human heart is shown. valves valves muscle Which row describes the function of the valves and the action of the muscles when blood is pumped out of the heart? valves muscles A allow blood to flow in both directions contract B allow blood to flow in both directions relax C allow blood to flow in one direction only contract D allow blood to flow in one direction only relax

1 marks

Answer: C

This question in 0653/23 May/June 2024

8 What happens after blood has filled the atria of the heart? muscles of muscles of valves between the atria the ventricles atria and ventricles A contract contract open B relax contract close C contract relax open D relax relax close

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2024

6 The diagram shows a section through the human heart. The four valves are labelled W, X, Y and Z. X W Z Y When the left ventricle contracts, valve Y closes. Which row shows the position of the other valves when valve Y is closed? valve W valve X valve Z A closed closed closed B open closed open C open open closed D open open open

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2024

8 Which row shows how blood is pumped out of the heart to the lungs? atria ventricles A left atrium contracts left ventricle relaxes B left atrium relaxes left ventricle contracts C right atrium contracts right ventricle relaxes D right atrium relaxes right ventricle contracts

1 marks

Answer: D

This question in 0653/22 Feb/March 2025

8 Which row shows possible causes of coronary heart disease? ner smoking stress A J J J B J x J Cc x J J D x x x

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2025

10 Which factors are possible risk factors for coronary heart disease? 1 age 2 genetic predisposition 3 sex A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

1 marks

Answer: A

This question in 0653/22 Oct/Nov 2025

8 Which row explains the effect of physical activity on heart rate? heart rate explanation A decreases increases blood flow to the muscles B decreases decreases blood flow to the muscles C increases increases blood flow to the muscles D increases decreases blood flow to the muscles

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2025