B13.1· 54 questions · 54 marks · 65 min · 2005–2024· Multiple choice
Every Cambridge IGCSE Science - Combined Paper 1 question on drugs, laid out as 14 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.



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14 / 14Answers below. Sit the paper first if you are practising.
Pastlit
Science - Combined 0653 · Drugs — Paper 1
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
Pastlit
Science - Combined 0653 · Drugs — Paper 1
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
| Question | Answer | Marks | From |
|---|---|---|---|
| 1 | A | 1 | 0653/11 Oct/Nov 2005 |
| 2 | D | 1 | 0653/11 May/June 2008 |
| 3 | C | 1 | 0653/11 May/June 2010 |
| 4 | C | 1 | 0653/12 May/June 2010 |
| 5 | C | 1 | 0653/13 May/June 2010 |
| 6 | A | 1 | 0653/11 May/June 2011 |
| 7 | A | 1 | 0653/12 May/June 2011 |
| 8 | D | 1 | 0653/11 Oct/Nov 2011 |
| 9 | A | 1 | 0653/12 Oct/Nov 2011 |
| 10 | D | 1 | 0653/12 Oct/Nov 2011 |
| 11 | D | 1 | 0653/13 Oct/Nov 2011 |
| 12 | see sheet | 1 | 0653/11 May/June 2012 |
| 13 | C | 1 | 0653/12 May/June 2012 |
| 14 | C | 1 | 0653/13 May/June 2012 |
| 15 | D | 1 | 0653/13 May/June 2013 |
| 16 | B | 1 | 0653/11 May/June 2014 |
| 17 | A | 1 | 0653/11 Oct/Nov 2014 |
| 18 | A | 1 | 0653/12 Oct/Nov 2014 |
| 19 | D | 1 | 0653/13 Oct/Nov 2014 |
| 20 | B | 1 | 0653/13 Oct/Nov 2015 |
| 21 | D | 1 | 0653/11 May/June 2016 |
| 22 | B | 1 | 0653/13 May/June 2016 |
| 23 | D | 1 | 0653/13 Oct/Nov 2016 |
| 24 | D | 1 | 0653/12 Feb/March 2017 |
| 25 | A | 1 | 0653/11 May/June 2017 |
| 26 | D | 1 | 0653/11 Oct/Nov 2017 |
| 27 | D | 1 | 0653/12 Oct/Nov 2017 |
| 28 | A | 1 | 0653/13 Oct/Nov 2017 |
| 29 | A | 1 | 0653/12 May/June 2018 |
| 30 | A | 1 | 0653/13 May/June 2018 |
| 31 | C | 1 | 0653/12 Oct/Nov 2018 |
| 32 | A | 1 | 0653/13 Oct/Nov 2018 |
| 33 | D | 1 | 0653/11 May/June 2019 |
| 34 | D | 1 | 0653/12 May/June 2019 |
| 35 | D | 1 | 0653/13 May/June 2019 |
| 36 | D | 1 | 0653/11 Oct/Nov 2019 |
| 37 | D | 1 | 0653/12 Feb/March 2020 |
| 38 | A | 1 | 0653/11 Oct/Nov 2020 |
| 39 | D | 1 | 0653/12 Oct/Nov 2020 |
| 40 | A | 1 | 0653/11 May/June 2021 |
| 41 | D | 1 | 0653/12 May/June 2021 |
| 42 | B | 1 | 0653/11 May/June 2022 |
| 43 | D | 1 | 0653/12 May/June 2022 |
| 44 | C | 1 | 0653/13 May/June 2022 |
| 45 | D | 1 | 0653/11 Oct/Nov 2022 |
| 46 | C | 1 | 0653/12 Oct/Nov 2022 |
| 47 | C | 1 | 0653/13 Oct/Nov 2022 |
| 48 | B | 1 | 0653/12 Feb/March 2023 |
| 49 | C | 1 | 0653/12 May/June 2023 |
| 50 | B | 1 | 0653/13 May/June 2023 |
| 51 | D | 1 | 0653/12 May/June 2024 |
| 52 | D | 1 | 0653/13 May/June 2024 |
| 53 | D | 1 | 0653/11 Oct/Nov 2024 |
| 54 | D | 1 | 0653/12 Oct/Nov 2024 |
8 What causes the signals passing along the nerves to slow down? A drinking alcohol B eating fat C running D smoking
1 marks
Answer: A
8 How does drinking alcohol affect the nervous system? time taken for impulse to time taken for impulse to pass from receptor to CNS pass from CNS to effector A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 What effect does drinking alcohol have on the following: • the rate at which signals pass along nerves, • the length of reaction time? rate at which signals length of pass along nerves reaction time A faster longer B faster shorter C slower longer D slower shorter
1 marks
Answer: C
8 What effect does drinking alcohol have on the following: • the rate at which signals pass along nerves, • the length of reaction time? rate at which signals length of pass along nerves reaction time A faster longer B faster shorter C slower longer D slower shorter
1 marks
Answer: C
8 What effect does drinking alcohol have on the following: • the rate at which signals pass along nerves, • the length of reaction time? rate at which signals length of pass along nerves reaction time A faster longer B faster shorter C slower longer D slower shorter
1 marks
Answer: C
5 Which health problems may result from smoking cigarettes? bronchitis emphysema lung cancer A v v v B v x x Cc x v v D x v x key Jv = yes xX =no
1 marks
Answer: A
8 Which health problems may result from smoking cigarettes? bronchitis emphysema lung cancer A v v v B v x x Cc x v v D x v x key v/=yes X =no
1 marks
Answer: A
8 The table shows the level of alcohol in a person’s blood after drinking two litres of beer. time after drinking alcohol in the blood beer (hours) (grams / dm3) 1 7 2 5 3 3 4 0 How long will it be (in hours) before the person’s reaction time returns to normal? A 0 to 1 B 1 to 2 C 2 to 3 D 3 to 4
1 marks
Answer: D
8 Which method of family planning is also likely to reduce the risk of the spread of syphilis? A condom B intra-uterine device (IUD) C pill D sterilisation
1 marks
Answer: A
10 The table shows the level of alcohol in a person’s blood after drinking two litres of beer. time after drinking alcohol in the blood beer (hours) (grams / dm3) 1 7 2 5 3 3 4 0 How long will it be (in hours) before the person’s reaction time returns to normal? A 0 to 1 B 1 to 2 C 2 to 3 D 3 to 4
1 marks
Answer: D
9 The table shows the level of alcohol in a person’s blood after drinking two litres of beer. time after drinking alcohol in the blood beer (hours) (grams / dm3) 1 7 2 5 3 3 4 0 How long will it be (in hours) before the person’s reaction time returns to normal? A 0 to 1 B 1 to 2 C 2 to 3 D 3 to 4
1 marks
Answer: D
9 The graphs show changes in the rate of heartbeat and in the concentration of sugar in the blood over the same period of time. When was adrenaline secreted? concentration of sugar in blood / arbitrary units time heart rate / arbitrary units time A B C D
1 marks
9 The graphs show changes in the rate of heartbeat and in the concentration of sugar in the blood over the same period of time. When was adrenaline secreted? concentration of sugar in blood / arbitrary units time heart rate / arbitrary units time A B C D
1 marks
Answer: C
9 The graphs show changes in the rate of heartbeat and in the concentration of sugar in the blood over the same period of time. When was adrenaline secreted? concentration of sugar in blood / arbitrary units time heart rate / arbitrary units time A B C D
1 marks
Answer: C
8 What is the effect of adrenaline in the control of metabolic activity? blood glucose rate of heart beat concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 Which situation is most likely to cause an increase in the secretion of adrenaline? A A person eats a meal rich in glucose. B A person is awoken suddenly by thunder and lightning. C A person’s blood glucose level decreases because they have not eaten. D A person’s pulse rate falls while they are asleep.
1 marks
Answer: B
11 A student is frightened by a dog and runs away. The changes in the concentration of adrenaline in the student’s blood are shown in the graph. 5 4 concentration of adrenaline 3 in the blood / arbitrary units 2 1 0 0 5 10 15 20 25 30 35 time / minutes frightened by dog What explains the gradual fall in the adrenaline concentration after the fright? A It is destroyed by the liver. B It is reabsorbed by the glands that produced it. C It is respired to release energy. D It is used up by the contracting muscles.
1 marks
Answer: A
12 A student is frightened by a dog and runs away. The changes in the concentration of adrenaline in the student’s blood are shown in the graph. 5 4 concentration of adrenaline 3 in the blood / arbitrary units 2 1 0 0 5 10 15 20 25 30 35 time / minutes frightened by dog What explains the gradual fall in the adrenaline concentration after the fright? A It is destroyed by the liver. B It is reabsorbed by the glands that produced it. C It is respired to release energy. D It is used up by the contracting muscles.
1 marks
Answer: A
10 Insulin is a hormone that is secreted into the blood to control blood sugar. What happens to insulin after it has done its work? A It builds up in the blood. B It is absorbed by the sugar. C It is destroyed by the pancreas. D It is removed by the liver.
1 marks
Answer: D
9 Which are effects of the hormone adrenaline? increase in i decrease in blood glucose ulse rate concentration 7 A v v B v x Cc x v D x x
1 marks
Answer: B
10 Four people have the same resting pulse rate and the same blood glucose concentration. The table shows their pulse rates and blood glucose concentrations later on the same day. Which person has the highest concentration of adrenaline in their blood? blood glucose pulse rate / beats concentration / per minute mg per dm3 A 70 65 B 70 100 C 120 65 D 120 100
1 marks
Answer: D
10 What happens to adrenaline after it has had its effect? A It is breathed out of the lungs as vapour. B It is destroyed by the liver. C It is egested in the alimentary canal. D It is used in respiration.
1 marks
Answer: B
9 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 Which row shows an effect of the hormone adrenaline, and the organ where adrenaline is broken down? organ where adrenaline effect of adrenaline is broken down A decreases blood glucose concentration heart B decreases blood glucose concentration liver C increases blood glucose concentration heart D increases blood glucose concentration liver
1 marks
Answer: D
9 Which statement about hormones in humans is correct? A They are destroyed by the liver. B They are destroyed by the pancreas. C They are produced by target organs. D They are produced by the blood.
1 marks
Answer: A
9 When someone is scared, adrenaline is released into their bloodstream. What is the effect of adrenaline on their blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
10 Which changes occur in an athlete just before the start of a race? adrenaline glucose in pulse rate in the blood the blood A decreases decreases increases B decreases increases decreases C increases decreases decreases D increases increases increases
1 marks
Answer: D
10 Which statements about hormones are correct? 1 They are carried by the blood. 2 They are chemical substances. 3 They are destroyed by the pancreas. 4 They are produced by a target organ. A 1 and 2 B 1 and 3 C 2 and 4 D 3 and 4
1 marks
Answer: A
9 Adrenaline is sometimes called the ‘fight or flight’ hormone. Which is an effect of adrenaline that helps prepare the body to fight or to take flight when frightened? A It increases blood glucose concentration. B It increases the rate of digestion. C It maintains a constant body temperature. D It slows down the heart rate.
1 marks
Answer: A
9 Adrenaline is sometimes called the ‘fight or flight’ hormone. Which is an effect of adrenaline that helps prepare the body to fight or to take flight when frightened? A It increases blood glucose concentration. B It increases the rate of digestion. C It maintains a constant body temperature. D It slows down the heart rate.
1 marks
Answer: A
8 What happens to the blood glucose concentration and pulse rate when adrenaline is released into a person’s bloodstream? blood glucose pulse rate concentration A decreases increases B decreases decreases C increases increases D increases decreases
1 marks
Answer: C
8 Which statement about adrenaline is not correct? A It decreases blood glucose concentration. B It is carried by the blood. C It is produced by a gland. D The heart is one of its target organs.
1 marks
Answer: A
8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
7 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
7 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 When an athlete prepares for the start of a sprint race, excitement causes the concentration of adrenaline in the blood to increase. What effects does adrenaline have on the blood glucose concentration and the heart rate of the athlete? blood glucose heart rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one target organ. D It reduces the size of the pupils.
1 marks
Answer: A
10 What are the effects of adrenaline on the human body? breathing rate pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 What are effects of increased adrenaline production in humans? A increased rate of breathing and increased pulse rate B increased rate of breathing and narrower pupils C slower pulse rate and narrower pupils D slower pulse rate and wider pupils
1 marks
Answer: A
10 When the hormone adrenaline is released in humans it causes changes in breathing rate and pupil size. What are the correct changes? breathing rate pupil size A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
9 Which responses occur as a result of adrenaline secretion? increased decreased increased breathing rate | pupil diameter pulse rate A v x x B J x J Cc x Jv J D x Jv x key JY = does occur X = does not occur
1 marks
Answer: B
9 Some examples of responses in the body are listed. 1 decreased pupil diameter 2 increased breathing rate 3 increased pulse rate Which responses are caused by the secretion of adrenaline? A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
1 marks
Answer: D
10 Some statements about adrenaline are listed. 1 It has one target organ. 2 It is a hormone. 3 It is produced by a gland. 4 It is transported in the blood. Which statements are correct? A 1, 2 and 3 only B 1, 2 and 4 only C 2, 3 and 4 only D 1, 2, 3 and 4
1 marks
Answer: C
9 Adrenaline is secreted during ‘fight or flight’ situations. Which combination of effects does adrenaline cause? A decreased breathing rate and wider pupils B decreased pulse rate and narrower pupils C increased breathing rate and decreased pulse rate D increased pulse rate and wider pupils
1 marks
Answer: D
10 Some examples of responses in the body are listed. 1 increased breathing rate 2 increased digestion rate 3 increased pulse rate 4 widened pupils Which responses are caused by the hormone adrenaline? A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
1 marks
Answer: C
10 Some examples of responses in the body are listed. 1 increased breathing rate 2 increased digestion rate 3 increased pulse rate 4 widened pupils Which responses are caused by the hormone adrenaline? A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
1 marks
Answer: C
10 In which situations does the secretion of adrenaline increase? 1 an athlete waiting for the starting signal at the beginning of a race 2 a mother zebra seeing a lion moving towards her offspring 3 a child about to fall asleep A 1, 2 and 3 B 1 and 2 only C 1 only D 2 and 3 only
1 marks
Answer: B
9 Which physical changes occur in response to a fear stimulus? adrenaline concentration pulse rate size of pupil in the blood A decreases increases narrower B decreases decreases wider C increases increases wider D increases decreases narrower
1 marks
Answer: C
9 Which situation is most likely to cause a sudden rise in the release of adrenaline into the blood? A beginning gentle exercise B being startled or alarmed C digestion of food during a meal D going to sleep when drowsy
1 marks
Answer: B
10 A cat suddenly jumps in front of a person walking down a street. The person is shocked. Which row shows the changes that occur? adrenaline level pulse rate A unchanged decreases B unchanged increases C increases decreases D increases increases
1 marks
Answer: D
10 Which row is correct for the hormone adrenaline? effect on effect on the blood glucose pulse rate concentration A lowered decreased B lowered increased C raised decreased D raised increased
1 marks
Answer: D
9 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 Which row shows effects of increased adrenaline secretion on the body? breathing rate size of pupils A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D