TopicalScience - Combined 0653DrugsDrugsPaper 2

Drugs — Paper 2 · IGCSE Science - Combined 0653

B13.1· 35 questions · 35 marks · 42 min · 2017–2025· Multiple choice

Every Cambridge IGCSE Science - Combined Paper 2 question on drugs, laid out as 8 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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Questions8 pages

Question 1: Which component of cigarette smoke reduces the oxygen-carrying capacity of the blood? A carbon monoxide B nicotine C smoke particles D tarQuestion 2: Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tarQuestion 3: Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tarQuestion 4: What is the role of microorganisms in the manufacture of yoghurt? A to turn lactic acid into lactose sugar and lower the pH B to turn lacti…Question 5: Why is tar in cigarette smoke a harmful chemical? A It causes addiction. B It causes cancer. C It makes platelets stick together. D It stic…Question 6: Adrenaline is sometimes called the ‘fight or flight’ hormone. Which is an effect of adrenaline that helps prepare the body to fight or to t…1 / 8
Question 7: Which substance is broken down to produce lactic acid during the manufacture of yoghurt? A glucose B lactose C protein D starchQuestion 8: Microorganisms are used to make yoghurt. Which acid is produced when microorganisms break down lactose in the milk? A amino acid B fatty ac…Question 9: What happens to the blood glucose concentration and pulse rate when adrenaline is released into a person’s bloodstream? blood glucose pulse…Question 10: Which statement about adrenaline is not correct? A It decreases blood glucose concentration. B It is carried by the blood. C It is produced…Question 11: How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decre…2 / 8
Question 12: How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decre…Question 13: How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decre…Question 14: What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases in…Question 15: Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tarQuestion 16: When an athlete prepares for the start of a sprint race, excitement causes the concentration of adrenaline in the blood to increase. What e…3 / 8
Question 17: Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tarQuestion 18: Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one tar…Question 19: Which row about the effects of adrenaline in humans is correct? blood glucose pulse rate concentration A increases decreases B increases in…Question 20: A person's body secretes adrenaline in response to a frightening experience. Which statement is correct? A The person's blood glucose conce…Question 21: What are effects of increased adrenaline production in humans? A increased rate of breathing and increased pulse rate B increased rate of b…4 / 8
Question 22: Which graph shows the correct changes in blood glucose concentration and pulse rate shortly after adrenaline is released into the blood str…Question 23: Which responses occur as a result of adrenaline secretion?

increased decreased increased
breathing rate | pupil diameter pulse rate
A v x …Question 24: The table shows two components of tobacco smoke and their possible effects on the body.

effects on the body

component in

tobacco smoke d…5 / 8
Question 25: Some examples of responses in the body are listed. 1 decreased pupil diameter 2 increased breathing rate 3 increased pulse rate Which respo…Question 26: Which row shows the correct changes when the hormone adrenaline is secreted? blood breathing pulse glucose rate rate A decreases decreases …Question 27: What are two effects of the secretion of adrenaline on the human body? A decreased blood glucose concentration and decreased pulse rate B d…Question 28: Adrenaline is produced by the adrenal glands in times of ......1...... . It targets vital organs, increases ......2...... which increases t…Question 29: What happens when adrenaline is released into the blood? blood glucose pulse rate concentration A increases increases B increases decreases…6 / 8
Question 30: What is caused by the secretion of adrenaline? blood glucose pulse rate pupil size concentration A decreases decreases increases B decrease…Question 31: Cigarette smoke contains carbon monoxide, nicotine and tar. These substances are harmful to human health. Which row gives the correct infor…Question 32: Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one tar…Question 33: When the hormone adrenaline is released in humans it causes changes in breathing rate and pupil size. What are the correct changes? breathi…Question 34: Which statements about antibiotics are correct? 1 An antibiotic is a drug. 2 Antibiotics kill bacteria and viruses. 3 MRSA is a type of bac…7 / 8
Question 35: Which statement about the use of antibiotics is correct? A Overuse of antibiotics causes the development of bacteria such as MRSA. B Antibi…8 / 8

Mark scheme35 answers

Answers below. Sit the paper first if you are practising.

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Science - Combined 0653 · Drugs — Paper 2

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1A1
2D1
3A1
4C1
5B1
6A1
7B1
8D1
9C1
10A1
11D1
12D1
13D1
14D1
15D1
16D1
17A1
18A1
19B1
20C1
21A1
22D1
23B1
24C1
25D1
26D1
27D1
28A1
29A1
30D1
31B1
32A1
33D1
34B1
35A1
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All of Drugs

Questions as text

Q1 · Which component of cigarette smoke reduces the oxygen-carrying capacity of the blood? 0653/22 Feb/March 2017

8 Which component of cigarette smoke reduces the oxygen-carrying capacity of the blood? A carbon monoxide B nicotine C smoke particles D tar

1 marks

Answer: A

This question in 0653/22 Feb/March 2017

Q2 · Which component of tobacco smoke increases the risk of lung cancer? 0653/23 May/June 2017

9 Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tar

1 marks

Answer: D

This question in 0653/23 May/June 2017

Q3 · Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? 0653/21 Oct/Nov 2017

10 Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tar

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2017

Q4 · What is the role of microorganisms in the manufacture of yoghurt? 0653/22 Oct/Nov 2017

3 What is the role of microorganisms in the manufacture of yoghurt? A to turn lactic acid into lactose sugar and lower the pH B to turn lactic acid into lactose sugar and raise the pH C to turn lactose sugar into lactic acid and lower the pH D to turn lactose sugar into lactic acid and raise the pH

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2017

Q5 · Why is tar in cigarette smoke a harmful chemical? 0653/21 May/June 2018

8 Why is tar in cigarette smoke a harmful chemical? A It causes addiction. B It causes cancer. C It makes platelets stick together. D It sticks to blood vessel walls.

1 marks

Answer: B

This question in 0653/21 May/June 2018

Q6 · Adrenaline is sometimes called the ‘fight or flight’ hormone 0653/22 May/June 2018

8 Adrenaline is sometimes called the ‘fight or flight’ hormone. Which is an effect of adrenaline that helps prepare the body to fight or to take flight when frightened? A It increases blood glucose concentration. B It increases the rate of digestion. C It maintains a constant body temperature. D It slows down the heart rate.

1 marks

Answer: A

This question in 0653/22 May/June 2018

Q7 · Which substance is broken down to produce lactic acid during the manufacture of yoghurt? 0653/23 May/June 2018

3 Which substance is broken down to produce lactic acid during the manufacture of yoghurt? A glucose B lactose C protein D starch

1 marks

Answer: B

This question in 0653/23 May/June 2018

Q8 · Microorganisms are used to make yoghurt 0653/21 Oct/Nov 2018

4 Microorganisms are used to make yoghurt. Which acid is produced when microorganisms break down lactose in the milk? A amino acid B fatty acid C hydrochloric acid D lactic acid

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2018

Q9 · What happens to the blood glucose concentration and pulse rate when adrenaline is… 0653/22 Oct/Nov 2018

10 What happens to the blood glucose concentration and pulse rate when adrenaline is released into a person’s bloodstream? blood glucose pulse rate concentration A decreases increases B decreases decreases C increases increases D increases decreases

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2018

Q10 · Which statement about adrenaline is not correct? 0653/23 Oct/Nov 2018

9 Which statement about adrenaline is not correct? A It decreases blood glucose concentration. B It is carried by the blood. C It is produced by a gland. D The heart is one of its target organs.

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2018

Q11 · How does adrenaline affect blood glucose concentration and pulse rate? 0653/21 May/June 2019

8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/21 May/June 2019

Q12 · How does adrenaline affect blood glucose concentration and pulse rate? 0653/22 May/June 2019

8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/22 May/June 2019

Q13 · How does adrenaline affect blood glucose concentration and pulse rate? 0653/23 May/June 2019

8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/23 May/June 2019

Q14 · What is the effect of adrenaline on the rate of breathing and pulse rate? 0653/21 Oct/Nov 2019

8 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2019

Q15 · Which component of tobacco smoke increases the risk of lung cancer? 0653/22 Feb/March 2020

7 Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tar

1 marks

Answer: D

This question in 0653/22 Feb/March 2020

Q16 · When an athlete prepares for the start of a sprint race, excitement causes the… 0653/22 Feb/March 2020

9 When an athlete prepares for the start of a sprint race, excitement causes the concentration of adrenaline in the blood to increase. What effects does adrenaline have on the blood glucose concentration and the heart rate of the athlete? blood glucose heart rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/22 Feb/March 2020

Q17 · Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? 0653/22 May/June 2020

7 Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tar

1 marks

Answer: A

This question in 0653/22 May/June 2020

Q18 · Which statement about adrenaline is correct? 0653/21 Oct/Nov 2020

9 Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one target organ. D It reduces the size of the pupils.

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2020

Q19 · Which row about the effects of adrenaline in humans is correct? 0653/22 Oct/Nov 2020

7 Which row about the effects of adrenaline in humans is correct? blood glucose pulse rate concentration A increases decreases B increases increases C stays the same decreases D stays the same increases

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2020

Q20 · A person's body secretes adrenaline in response to a frightening experience 0653/23 Oct/Nov 2020

8 A person's body secretes adrenaline in response to a frightening experience. Which statement is correct? A The person's blood glucose concentration decreases. B The person's breathing rate does not change. C The person's pulse rate increases. D The person's pupils become narrower.

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2020

Q21 · What are effects of increased adrenaline production in humans? 0653/21 May/June 2021

8 What are effects of increased adrenaline production in humans? A increased rate of breathing and increased pulse rate B increased rate of breathing and narrower pupils C slower pulse rate and narrower pupils D slower pulse rate and wider pupils

1 marks

Answer: A

This question in 0653/21 May/June 2021

Q22 · Which graph shows the correct changes in blood glucose concentration and pulse rate… 0653/22 May/June 2021

9 Which graph shows the correct changes in blood glucose concentration and pulse rate shortly after adrenaline is released into the blood stream? A B key blood glucose pulse rate time time C D time time

1 marks

Answer: D

This question in 0653/22 May/June 2021

Q23 · Which responses occur as a result of adrenaline secretion? 0653/21 May/June 2022

9 Which responses occur as a result of adrenaline secretion? increased decreased increased breathing rate | pupil diameter pulse rate A v x x B J x J Cc x Jv J D x Jv x key JY = does occur X = does not occur

1 marks

Answer: B

This question in 0653/21 May/June 2022

Q24 · The table shows two components of tobacco smoke and their possible effects on the body 0653/22 May/June 2022

7 The table shows two components of tobacco smoke and their possible effects on the body. effects on the body component in tobacco smoke decreased oxygen increased absorption by blood blood pressure 1 carbon monoxide x v 2 carbon monoxide v x 3 nicotine x v 4 nicotine v x Which rows show the correct effects of each component? A 1and3 B 1and4 C 2and3 D 2and4

1 marks

Answer: C

This question in 0653/22 May/June 2022

Q25 · Some examples of responses in the body are listed 0653/22 May/June 2022

9 Some examples of responses in the body are listed. 1 decreased pupil diameter 2 increased breathing rate 3 increased pulse rate Which responses are caused by the secretion of adrenaline? A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

1 marks

Answer: D

This question in 0653/22 May/June 2022

Q26 · Which row shows the correct changes when the hormone adrenaline is secreted? 0653/21 Oct/Nov 2022

10 Which row shows the correct changes when the hormone adrenaline is secreted? blood breathing pulse glucose rate rate A decreases decreases decreases B increases decreases increases C decreases increases decreases D increases increases increases

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2022

Q27 · What are two effects of the secretion of adrenaline on the human body? 0653/22 Oct/Nov 2022

9 What are two effects of the secretion of adrenaline on the human body? A decreased blood glucose concentration and decreased pulse rate B decreased blood glucose concentration and increased pulse rate C increased blood glucose concentration and decreased pulse rate D increased blood glucose concentration and increased pulse rate

1 marks

Answer: D

This question in 0653/22 Oct/Nov 2022

Q28 · Adrenaline is produced by the adrenal glands in times of … 1 … 0653/22 Feb/March 2023

8 Adrenaline is produced by the adrenal glands in times of … 1 … . It targets vital organs, increases … 2 … which increases the delivery of oxygen and … 3 … to the brain and muscles, preparing the body for 'flight or fight'. Which words complete gaps 1, 2 and 3? 1 2 3 A stress heart rate glucose B stress breathing rate glycogen C relaxation breathing rate glucose D relaxation heart rate glycogen

1 marks

Answer: A

This question in 0653/22 Feb/March 2023

Q29 · What happens when adrenaline is released into the blood? 0653/22 May/June 2023

10 What happens when adrenaline is released into the blood? blood glucose pulse rate concentration A increases increases B increases decreases C decreases increases D decreases decreases

1 marks

Answer: A

This question in 0653/22 May/June 2023

Q30 · What is caused by the secretion of adrenaline? 0653/23 May/June 2023

9 What is caused by the secretion of adrenaline? blood glucose pulse rate pupil size concentration A decreases decreases increases B decreases increases decreases C increases decreases decreases D increases increases increases

1 marks

Answer: D

This question in 0653/23 May/June 2023

Q31 · Cigarette smoke contains carbon monoxide, nicotine and tar 0653/22 Oct/Nov 2023

7 Cigarette smoke contains carbon monoxide, nicotine and tar. These substances are harmful to human health. Which row gives the correct information about the harmful effects? combines with causes haemoglobin lung cancer A carbon monoxide nicotine B carbon monoxide tar C tar carbon monoxide D nicotine carbon monoxide

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2023

Q32 · Which statement about adrenaline is correct? 0653/21 May/June 2024

8 Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one target organ. D It reduces the size of the pupils.

1 marks

Answer: A

This question in 0653/21 May/June 2024

Q33 · When the hormone adrenaline is released in humans it causes changes in breathing rate and… 0653/22 May/June 2024

9 When the hormone adrenaline is released in humans it causes changes in breathing rate and pupil size. What are the correct changes? breathing rate pupil size A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0653/22 May/June 2024

Q34 · Which statements about antibiotics are correct? 0653/21 May/June 2025

13 Which statements about antibiotics are correct? 1 An antibiotic is a drug. 2 Antibiotics kill bacteria and viruses. 3 MRSA is a type of bacteria resistant to antibiotics. A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

1 marks

Answer: B

This question in 0653/21 May/June 2025

Q35 · Which statement about the use of antibiotics is correct? 0653/22 May/June 2025

12 Which statement about the use of antibiotics is correct? A Overuse of antibiotics causes the development of bacteria such as MRSA. B Antibiotics are prescribed for infections caused by viruses and bacteria. C Antibiotics increase reproduction of non-resistant bacteria. D Antibiotics only kill resistant bacteria.

1 marks

Answer: A

This question in 0653/22 May/June 2025