B13.1· 35 questions · 35 marks · 42 min · 2017–2025· Multiple choice
Every Cambridge IGCSE Science - Combined Paper 2 question on drugs, laid out as 8 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.





1 / 8



2 / 8



3 / 8



4 / 8

5 / 8



6 / 8



7 / 8
8 / 8Answers below. Sit the paper first if you are practising.
Pastlit
Science - Combined 0653 · Drugs — Paper 2
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
| Question | Answer | Marks | From |
|---|---|---|---|
| 1 | A | 1 | 0653/22 Feb/March 2017 |
| 2 | D | 1 | 0653/23 May/June 2017 |
| 3 | A | 1 | 0653/21 Oct/Nov 2017 |
| 4 | C | 1 | 0653/22 Oct/Nov 2017 |
| 5 | B | 1 | 0653/21 May/June 2018 |
| 6 | A | 1 | 0653/22 May/June 2018 |
| 7 | B | 1 | 0653/23 May/June 2018 |
| 8 | D | 1 | 0653/21 Oct/Nov 2018 |
| 9 | C | 1 | 0653/22 Oct/Nov 2018 |
| 10 | A | 1 | 0653/23 Oct/Nov 2018 |
| 11 | D | 1 | 0653/21 May/June 2019 |
| 12 | D | 1 | 0653/22 May/June 2019 |
| 13 | D | 1 | 0653/23 May/June 2019 |
| 14 | D | 1 | 0653/21 Oct/Nov 2019 |
| 15 | D | 1 | 0653/22 Feb/March 2020 |
| 16 | D | 1 | 0653/22 Feb/March 2020 |
| 17 | A | 1 | 0653/22 May/June 2020 |
| 18 | A | 1 | 0653/21 Oct/Nov 2020 |
| 19 | B | 1 | 0653/22 Oct/Nov 2020 |
| 20 | C | 1 | 0653/23 Oct/Nov 2020 |
| 21 | A | 1 | 0653/21 May/June 2021 |
| 22 | D | 1 | 0653/22 May/June 2021 |
| 23 | B | 1 | 0653/21 May/June 2022 |
| 24 | C | 1 | 0653/22 May/June 2022 |
| 25 | D | 1 | 0653/22 May/June 2022 |
| 26 | D | 1 | 0653/21 Oct/Nov 2022 |
| 27 | D | 1 | 0653/22 Oct/Nov 2022 |
| 28 | A | 1 | 0653/22 Feb/March 2023 |
| 29 | A | 1 | 0653/22 May/June 2023 |
| 30 | D | 1 | 0653/23 May/June 2023 |
| 31 | B | 1 | 0653/22 Oct/Nov 2023 |
| 32 | A | 1 | 0653/21 May/June 2024 |
| 33 | D | 1 | 0653/22 May/June 2024 |
| 34 | B | 1 | 0653/21 May/June 2025 |
| 35 | A | 1 | 0653/22 May/June 2025 |
8 Which component of cigarette smoke reduces the oxygen-carrying capacity of the blood? A carbon monoxide B nicotine C smoke particles D tar
1 marks
Answer: A
9 Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tar
1 marks
Answer: D
10 Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tar
1 marks
Answer: A
3 What is the role of microorganisms in the manufacture of yoghurt? A to turn lactic acid into lactose sugar and lower the pH B to turn lactic acid into lactose sugar and raise the pH C to turn lactose sugar into lactic acid and lower the pH D to turn lactose sugar into lactic acid and raise the pH
1 marks
Answer: C
8 Why is tar in cigarette smoke a harmful chemical? A It causes addiction. B It causes cancer. C It makes platelets stick together. D It sticks to blood vessel walls.
1 marks
Answer: B
8 Adrenaline is sometimes called the ‘fight or flight’ hormone. Which is an effect of adrenaline that helps prepare the body to fight or to take flight when frightened? A It increases blood glucose concentration. B It increases the rate of digestion. C It maintains a constant body temperature. D It slows down the heart rate.
1 marks
Answer: A
3 Which substance is broken down to produce lactic acid during the manufacture of yoghurt? A glucose B lactose C protein D starch
1 marks
Answer: B
4 Microorganisms are used to make yoghurt. Which acid is produced when microorganisms break down lactose in the milk? A amino acid B fatty acid C hydrochloric acid D lactic acid
1 marks
Answer: D
10 What happens to the blood glucose concentration and pulse rate when adrenaline is released into a person’s bloodstream? blood glucose pulse rate concentration A decreases increases B decreases decreases C increases increases D increases decreases
1 marks
Answer: C
9 Which statement about adrenaline is not correct? A It decreases blood glucose concentration. B It is carried by the blood. C It is produced by a gland. D The heart is one of its target organs.
1 marks
Answer: A
8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 How does adrenaline affect blood glucose concentration and pulse rate? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
8 What is the effect of adrenaline on the rate of breathing and pulse rate? rate of breathing pulse rate A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
7 Which component of tobacco smoke increases the risk of lung cancer? A carbon dioxide B carbon monoxide C nicotine D tar
1 marks
Answer: D
9 When an athlete prepares for the start of a sprint race, excitement causes the concentration of adrenaline in the blood to increase. What effects does adrenaline have on the blood glucose concentration and the heart rate of the athlete? blood glucose heart rate concentration A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
7 Which component of tobacco smoke reduces the ability of haemoglobin to carry oxygen? A carbon monoxide B nicotine C smoke particles D tar
1 marks
Answer: A
9 Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one target organ. D It reduces the size of the pupils.
1 marks
Answer: A
7 Which row about the effects of adrenaline in humans is correct? blood glucose pulse rate concentration A increases decreases B increases increases C stays the same decreases D stays the same increases
1 marks
Answer: B
8 A person's body secretes adrenaline in response to a frightening experience. Which statement is correct? A The person's blood glucose concentration decreases. B The person's breathing rate does not change. C The person's pulse rate increases. D The person's pupils become narrower.
1 marks
Answer: C
8 What are effects of increased adrenaline production in humans? A increased rate of breathing and increased pulse rate B increased rate of breathing and narrower pupils C slower pulse rate and narrower pupils D slower pulse rate and wider pupils
1 marks
Answer: A
9 Which graph shows the correct changes in blood glucose concentration and pulse rate shortly after adrenaline is released into the blood stream? A B key blood glucose pulse rate time time C D time time
1 marks
Answer: D
9 Which responses occur as a result of adrenaline secretion? increased decreased increased breathing rate | pupil diameter pulse rate A v x x B J x J Cc x Jv J D x Jv x key JY = does occur X = does not occur
1 marks
Answer: B
7 The table shows two components of tobacco smoke and their possible effects on the body. effects on the body component in tobacco smoke decreased oxygen increased absorption by blood blood pressure 1 carbon monoxide x v 2 carbon monoxide v x 3 nicotine x v 4 nicotine v x Which rows show the correct effects of each component? A 1and3 B 1and4 C 2and3 D 2and4
1 marks
Answer: C
9 Some examples of responses in the body are listed. 1 decreased pupil diameter 2 increased breathing rate 3 increased pulse rate Which responses are caused by the secretion of adrenaline? A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
1 marks
Answer: D
10 Which row shows the correct changes when the hormone adrenaline is secreted? blood breathing pulse glucose rate rate A decreases decreases decreases B increases decreases increases C decreases increases decreases D increases increases increases
1 marks
Answer: D
9 What are two effects of the secretion of adrenaline on the human body? A decreased blood glucose concentration and decreased pulse rate B decreased blood glucose concentration and increased pulse rate C increased blood glucose concentration and decreased pulse rate D increased blood glucose concentration and increased pulse rate
1 marks
Answer: D
8 Adrenaline is produced by the adrenal glands in times of … 1 … . It targets vital organs, increases … 2 … which increases the delivery of oxygen and … 3 … to the brain and muscles, preparing the body for 'flight or fight'. Which words complete gaps 1, 2 and 3? 1 2 3 A stress heart rate glucose B stress breathing rate glycogen C relaxation breathing rate glucose D relaxation heart rate glycogen
1 marks
Answer: A
10 What happens when adrenaline is released into the blood? blood glucose pulse rate concentration A increases increases B increases decreases C decreases increases D decreases decreases
1 marks
Answer: A
9 What is caused by the secretion of adrenaline? blood glucose pulse rate pupil size concentration A decreases decreases increases B decreases increases decreases C increases decreases decreases D increases increases increases
1 marks
Answer: D
7 Cigarette smoke contains carbon monoxide, nicotine and tar. These substances are harmful to human health. Which row gives the correct information about the harmful effects? combines with causes haemoglobin lung cancer A carbon monoxide nicotine B carbon monoxide tar C tar carbon monoxide D nicotine carbon monoxide
1 marks
Answer: B
8 Which statement about adrenaline is correct? A It is produced by a gland. B It is transported in the red blood cells. C It only has one target organ. D It reduces the size of the pupils.
1 marks
Answer: A
9 When the hormone adrenaline is released in humans it causes changes in breathing rate and pupil size. What are the correct changes? breathing rate pupil size A decreases decreases B decreases increases C increases decreases D increases increases
1 marks
Answer: D
13 Which statements about antibiotics are correct? 1 An antibiotic is a drug. 2 Antibiotics kill bacteria and viruses. 3 MRSA is a type of bacteria resistant to antibiotics. A 1 and 2 B 1 and 3 C 2 and 3 D 3 only
1 marks
Answer: B
12 Which statement about the use of antibiotics is correct? A Overuse of antibiotics causes the development of bacteria such as MRSA. B Antibiotics are prescribed for infections caused by viruses and bacteria. C Antibiotics increase reproduction of non-resistant bacteria. D Antibiotics only kill resistant bacteria.
1 marks
Answer: A