B14.2· 56 questions · 56 marks · 67 min · 2017–2024· Multiple choice
Every Cambridge IGCSE Science - Combined Paper 2 question on sexual reproduction in humans, laid out as 14 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.




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14 / 14Answers below. Sit the paper first if you are practising.
Pastlit
Science - Combined 0653 · Sexual reproduction in humans — Paper 2
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
Pastlit
Science - Combined 0653 · Sexual reproduction in humans — Paper 2
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
| Question | Answer | Marks | From |
|---|---|---|---|
| 1 | B | 1 | 0653/21 May/June 2017 |
| 2 | B | 1 | 0653/22 May/June 2017 |
| 3 | A | 1 | 0653/21 Oct/Nov 2017 |
| 4 | A | 1 | 0653/22 Oct/Nov 2017 |
| 5 | A | 1 | 0653/23 Oct/Nov 2017 |
| 6 | C | 1 | 0653/22 Feb/March 2018 |
| 7 | B | 1 | 0653/21 May/June 2018 |
| 8 | A | 1 | 0653/23 May/June 2018 |
| 9 | A | 1 | 0653/21 Oct/Nov 2018 |
| 10 | B | 1 | 0653/22 Oct/Nov 2018 |
| 11 | C | 1 | 0653/23 Oct/Nov 2018 |
| 12 | B | 1 | 0653/22 Feb/March 2019 |
| 13 | A | 1 | 0653/22 Feb/March 2019 |
| 14 | D | 1 | 0653/21 May/June 2019 |
| 15 | B | 1 | 0653/22 May/June 2019 |
| 16 | C | 1 | 0653/22 May/June 2019 |
| 17 | D | 1 | 0653/23 May/June 2019 |
| 18 | A | 1 | 0653/23 May/June 2019 |
| 19 | B | 1 | 0653/21 Oct/Nov 2019 |
| 20 | A | 1 | 0653/21 Oct/Nov 2019 |
| 21 | C | 1 | 0653/22 Oct/Nov 2019 |
| 22 | B | 1 | 0653/22 Oct/Nov 2019 |
| 23 | B | 1 | 0653/23 Oct/Nov 2019 |
| 24 | D | 1 | 0653/23 Oct/Nov 2019 |
| 25 | A | 1 | 0653/22 Feb/March 2020 |
| 26 | C | 1 | 0653/21 May/June 2020 |
| 27 | B | 1 | 0653/22 May/June 2020 |
| 28 | C | 1 | 0653/21 Oct/Nov 2020 |
| 29 | D | 1 | 0653/22 Oct/Nov 2020 |
| 30 | A | 1 | 0653/22 Oct/Nov 2020 |
| 31 | B | 1 | 0653/23 Oct/Nov 2020 |
| 32 | B | 1 | 0653/22 Feb/March 2021 |
| 33 | D | 1 | 0653/21 May/June 2021 |
| 34 | D | 1 | 0653/22 May/June 2021 |
| 35 | B | 1 | 0653/23 May/June 2021 |
| 36 | C | 1 | 0653/21 Oct/Nov 2021 |
| 37 | B | 1 | 0653/22 Oct/Nov 2021 |
| 38 | A | 1 | 0653/22 Oct/Nov 2021 |
| 39 | B | 1 | 0653/23 Oct/Nov 2021 |
| 40 | C | 1 | 0653/22 Feb/March 2022 |
| 41 | B | 1 | 0653/21 May/June 2022 |
| 42 | B | 1 | 0653/22 May/June 2022 |
| 43 | B | 1 | 0653/23 May/June 2022 |
| 44 | A | 1 | 0653/21 Oct/Nov 2022 |
| 45 | C | 1 | 0653/22 Oct/Nov 2022 |
| 46 | D | 1 | 0653/22 Oct/Nov 2022 |
| 47 | A | 1 | 0653/22 Feb/March 2023 |
| 48 | D | 1 | 0653/21 May/June 2023 |
| 49 | A | 1 | 0653/23 May/June 2023 |
| 50 | B | 1 | 0653/21 Oct/Nov 2023 |
| 51 | A | 1 | 0653/22 Feb/March 2024 |
| 52 | B | 1 | 0653/21 May/June 2024 |
| 53 | A | 1 | 0653/21 May/June 2024 |
| 54 | A | 1 | 0653/22 May/June 2024 |
| 55 | C | 1 | 0653/21 Oct/Nov 2024 |
| 56 | B | 1 | 0653/23 Oct/Nov 2024 |
11 Materials are exchanged between a mother and her fetus across the placenta. Which row shows the overall direction of movement of these materials? mother to fetus fetus to mother A amino acids glucose B amino acids urea C carbon dioxide glucose D carbon dioxide urea
1 marks
Answer: B
10 Which substance is at a higher concentration in the blood on the fetal side of the placenta than in the blood on the mother’s side of the placenta? A amino acids B carbon dioxide C glucose D oxygen
1 marks
Answer: B
11 During pregnancy, the fetus is contained within the amniotic sac. The amniotic sac contains amniotic fluid. What is the function of the amniotic fluid? A It protects the fetus against knocks and bumps. B It provides the fetus with oxygen and nutrients. C It removes the fetal waste products. D It supplies the fetus with blood.
1 marks
Answer: A
11 During pregnancy, the fetus is contained within the amniotic sac. The amniotic sac contains amniotic fluid. What is the function of the amniotic fluid? A It protects the fetus against knocks and bumps. B It provides the fetus with oxygen and nutrients. C It removes the fetal waste products. D It supplies the fetus with blood.
1 marks
Answer: A
11 During pregnancy, the fetus is contained within the amniotic sac. The amniotic sac contains amniotic fluid. What is the function of the amniotic fluid? A It protects the fetus against knocks and bumps. B It provides the fetus with oxygen and nutrients. C It removes the fetal waste products. D It supplies the fetus with blood.
1 marks
Answer: A
11 How do male gametes compare with female gametes? . move size independently A larger v B larger x Cc smaller v D smaller x
1 marks
Answer: C
11 The diagrams show the human male and female reproductive systems. 3 2 4 1 Which numbered parts produce gametes? A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
1 marks
Answer: B
12 What is a disadvantage of breast-feeding compared with bottle-feeding using formula milk? A difficult to measure the amount of milk given B milk contains antibodies C milk is always immediately available D milk is at the optimum temperature
1 marks
Answer: A
11 What is the function of the amniotic sac? A It surrounds the fetus in the uterus and contains amniotic fluid. B It surrounds the fetus in the uterus and provides essential nutrients for the fetus. C It surrounds the fetus in the vagina and contains amniotic fluid. D It surrounds the fetus in the vagina and provides essential nutrients for the fetus.
1 marks
Answer: A
11 Which row describes the net diffusion of substances between the fetus and the mother across the placenta? from fetus to mother from mother to fetus A carbon dioxide and glucose oxygen and amino acids B carbon dioxide and waste products oxygen and glucose C oxygen and glucose carbon dioxide and amino acid D oxygen and waste products carbon dioxide and glucose
1 marks
Answer: B
11 During pregnancy in humans, gas exchange occurs between a mother and her fetus. Where does this gas exchange occur? A amniotic fluid B amniotic sac C placenta D umbilical cord
1 marks
Answer: C
9 Which row is correct for sexual reproduction? genetically different one zygote offspring produced parent produced A v Jv x B J x J Cc x v x D x x J
1 marks
Answer: B
10 Four students are comparing the human male and female gametes. Which student has the correct comparison? size movement number A egg bigger sperm mobile usually one egg B sperm bigger sperm not mobile many eggs C egg bigger sperm not mobile one sperm D sperm bigger sperm mobile many sperm
1 marks
Answer: A
10 What are the features of sexual reproduction? fusion nature of offspring of nuclei A no genetically dissimilar B yes genetically identical C no genetically identical D yes genetically dissimilar
1 marks
Answer: D
7 The diagram shows the female reproductive system. X Y Z What are the functions of the parts labelled X, Y, and Z? X Y Z A development release of ring of muscle at of fetus female gametes opening of uterus B development site of receives penis of fetus fertilisation during intercourse C receives penis release of ring of muscle at during intercourse female gametes opening of uterus D receives penis site of development during intercourse fertilisation of fetus
1 marks
Answer: B
12 Which row shows the substances that diffuse from the mother to the fetus at the placenta? career nutrients oxygen oroduts A v x v x B v v x v Cc x v v x D x x v v
1 marks
Answer: C
10 What are the features of sexual reproduction? fusion nature of offspring of nuclei A no genetically dissimilar B yes genetically identical C no genetically identical D yes genetically dissimilar
1 marks
Answer: D
12 The diagram shows part of a placenta. vein artery mothers blood placenta membrane barrier umbilical vein umbilical artery Why do nutrients in the mother’s blood enter the blood in the umbilical vein? A A net movement of nutrient particles occurs from a region of high concentration to a lower concentration. B Nutrients move from a region of higher water potential to a region of lower water potential. C Pressure in the maternal blood forces nutrients into the umbilical vein. D The nutrients travel into the umbilical vein, across a partially permeable membrane by osmosis.
1 marks
Answer: A
10 Which statement about sexual reproduction is always correct? A It involves only one parent. B It involves the fusion of nuclei. C It produces genetically identical offspring. D It takes place only in animals.
1 marks
Answer: B
12 The following are adaptive features of some gametes. 1 a flagellum 2 a jelly coat 3 a sac of enzymes at one end 4 a store of energy Which are features of a human male gamete? A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
1 marks
Answer: A
2 Which statement about human gametes is correct? A Egg cells are much smaller than sperm cells. B Egg cells are produced in larger numbers than sperm cells. C Egg cells have a jelly coating that changes after fertilisation. D The flagellum is an adaptive feature of an egg cell.
1 marks
Answer: C
11 A developing fetus is connected to its mother by an umbilical cord and placenta. What is the function of the placenta? A to allow the mixing of the mother’s blood with the blood of the fetus B to exchange nutrients and waste C to keep the fetus warm D to stop the fetus from moving
1 marks
Answer: B
9 Which statement about sexual reproduction is always correct? A It involves only one parent. B It involves the fusion of nuclei. C It produces genetically identical offspring. D It takes place only in animals.
1 marks
Answer: B
11 Which statement about human gametes is correct? A Sperm cells are much larger than egg cells. B Sperm cells are produced in smaller numbers than egg cells. C Sperm cells have a jelly coating that changes after fertilisation. D The flagellum is an adaptive feature of a sperm cell.
1 marks
Answer: D
12 What gives the human embryo protection from mechanical shock? A amniotic fluid B amniotic sac C placenta D umbilical cord
1 marks
Answer: A
11 Which part of the male reproductive system in humans produces sperm? A penis B scrotum C testes D urethra
1 marks
Answer: C
12 Which row contains correct adaptive features for both sperm and egg cells? sperm egg A energy store presence of enzymes B flagellum jelly coat C jelly coat energy store D presence of enzymes flagellum
1 marks
Answer: B
12 The diagram shows a placenta and umbilical cord. X key umbilical artery X movement of oxygen from fetus to fetus X mother’s umbilical blood vein X Which row is correct? high oxygen low oxygen name of concentration concentration process X present present A umbilical artery umbilical vein diffusion B umbilical artery umbilical vein osmosis C umbilical vein umbilical artery diffusion D umbilical vein umbilical artery osmosis
1 marks
Answer: C
8 The following are features of human gametes. 1 have a jelly coat 2 have energy stores 3 have flagella 4 motile 5 produced in large numbers What are features of human male gametes? A 1 and 2 only B 1, 2 and 4 C 2, 3 and 5 D 3, 4 and 5
1 marks
Answer: D
11 The diagram shows a fetus in the uterus. Which letter identifies the umbilical cord? D A C B
1 marks
Answer: A
12 The diagram shows a male gamete and a female gamete. Which label is correct? A B D central vacuole jelly coat nucleus containing C chromosomes from mother food store
1 marks
Answer: B
12 Materials are exchanged between a mother and her fetus across the placenta. Which row shows the overall direction of movement of these materials? mother to fetus fetus to mother A amino acids glucose B amino acids urea C carbon dioxide glucose D carbon dioxide urea
1 marks
Answer: B
11 Materials are exchanged between the blood of the mother and embryo in the placenta. lining of maternal uterus blood placenta capillary network in placenta 1 2 embryo Which row shows the blood vessels with higher concentrations of carbon dioxide and glucose? higher concentration higher concentration of carbon dioxide of glucose A 1 1 B 2 2 C 2 1 D 1 2
1 marks
Answer: D
11 The diagram shows the human female reproductive system. Where does fertilisation usually take place? D C A B
1 marks
Answer: D
10 During human reproduction an egg fuses with a sperm. Sometimes the zygote splits into two and produces twins. Which row describes the formation of these twins? original zygote produced by twins A asexual reproduction genetically identical B sexual reproduction genetically identical C asexual reproduction genetically different D sexual reproduction genetically different
1 marks
Answer: B
11 The diagram represents the human placenta. P blood of blood of fetus Q mother placenta P and Q show the net movement of substances. Which row identifies substances that travel in the directions of P and Q? in direction P in direction Q A blood urea B oxygen carbon dioxide C excretory products glucose D amino acids toxins
1 marks
Answer: C
10 Which row is correct for sexual reproduction? gametes are offspring genetically formed identical to parents A no no B yes no C no yes D yes yes
1 marks
Answer: B
11 Which row correctly describes features of human egg cells and sperm cells? egg cells sperm cells A energy stores present enzymes present B enzymes present energy stores present C produced in large numbers flagellum present D flagellum present produced in large numbers
1 marks
Answer: A
11 Which comparison between human female and male gametes is correct? eggs sperm A have a flagellum have no flagellum B move a short distance move a long distance C produced in greater numbers produced in fewer numbers D smaller size larger size
1 marks
Answer: B
11 During pregnancy, what protects the embryo against toxins? A amniotic fluid B amniotic sac C placenta D umbilical cord
1 marks
Answer: C
11 During sexual intercourse the penis transfers sperm cells to the vagina. What is the pathway for sperm cells from their site of production to the vagina? A sperm ducts testes urethra vagina B testes sperm ducts urethra vagina C testes urethra sperm ducts vagina D urethra testes sperm ducts vagina
1 marks
Answer: B
12 During sexual intercourse the penis transfers sperm cells to the vagina. What is the pathway for sperm cells from their site of production to the vagina? A sperm ducts testes urethra vagina B testes sperm ducts urethra vagina C testes urethra sperm ducts vagina D urethra testes sperm ducts vagina
1 marks
Answer: B
12 During sexual intercourse the penis transfers sperm cells to the vagina. What is the pathway for sperm cells from their site of production to the vagina? A sperm ducts testes urethra vagina B testes sperm ducts urethra vagina C testes urethra sperm ducts vagina D urethra testes sperm ducts vagina
1 marks
Answer: B
13 What is the function of amniotic fluid? A to cushion the fetus B to remove carbon dioxide C to supply nutrients D to supply oxygen
1 marks
Answer: A
11 What are two features of sexual reproduction? feature 1 feature 2 A fusion of two identical nuclei requires two different parents B fusion of two zygotes offspring are genetically identical C offspring are genetically different fusion of two different nuclei D only requires a single parent development from a single zygote
1 marks
Answer: C
12 Which row is correct for the female gamete? released in can move large numbers by itself WA J 0 0O WwW D> v x x v x x
1 marks
Answer: D
11 Where does fertilisation take place? A B C D
1 marks
Answer: A
10 What are features of sexual reproduction? fusion nature of offspring of nuclei A no genetically different B yes genetically identical C no genetically identical D yes genetically different
1 marks
Answer: D
11. Which row shows the correct information about a human female gamete? v x v v x v x x
1 marks
Answer: A
11 Which row is correct for sexual reproduction? genetically different one zygote offspring produced parent produced
1 marks
Answer: B
11 Which row correctly describes features of human egg cells and sperm cells? egg cells sperm cells A energy stores present enzymes present B enzymes present energy stores present C produced in large numbers flagellum present D flagellum present produced in large numbers
1 marks
Answer: A
10 Which statement about sexual reproduction is always correct? A It involves only one parent. B It involves the fusion of nuclei. C It produces genetically identical offspring. D It takes place only in animals.
1 marks
Answer: B
12 The list shows the adaptive features of some gametes. 1 a flagellum 2 a jelly coat 3 a sac of enzymes at one end 4 a store of energy Which features are present in a human male gamete? A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
1 marks
Answer: A
12 What gives the human embryo protection from mechanical shock? A amniotic fluid B cervix C placenta D umbilical cord
1 marks
Answer: A
12 The diagram represents the human placenta. P blood of blood of fetus Q mother placenta P and Q show the net movement of substances. Which row identifies substances that travel in the directions P and Q? in direction P in direction Q A blood urea B oxygen carbon dioxide C excretory products glucose D amino acids toxins
1 marks
Answer: C
12 What is the function of the placenta? A to allow the mixing of the mother’s blood with the blood of the fetus B to exchange nutrients and waste C to keep the fetus warm D to stop the fetus from moving
1 marks
Answer: B