TopicalScience - Combined 0653Human nutritionDigestionPaper 2

Digestion — Paper 2 · IGCSE Science - Combined 0653

B7.3· 46 questions · 46 marks · 55 min · 2018–2025· Multiple choice

Every Cambridge IGCSE Science - Combined Paper 2 question on digestion, laid out as 13 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

Different topic or paper

Questions13 pages

Question 1: Enzymes are used in digestion to break down larger molecules into smaller molecules. Which row matches the large molecules with the small m…Question 2: What is defined as the breakdown of food into smaller pieces, without chemically changing the molecules? A absorption B chemical digestion …Question 3: The diagram shows an experiment at the start and one hour later. beaker water water and partially permeable simple sugars membrane starch s…Question 4: What is the purpose of mechanical digestion? A to break down food into smaller pieces B to break down insoluble foods into soluble particle…1 / 13
Question 5: 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed. Food tests are carried out immediately after mixing and again after an…Question 6: 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed. Food tests are carried out immediately after mixing and again after an…Question 7: Which are absorbed from the alimentary canal into the blood? 1 fibre 2 glucose 3 vitamin C A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1…Question 8: Animals break down large, insoluble molecules into small, soluble molecules in the alimentary canal. What is this process? A chemical diges…2 / 13
Question 9: Which row correctly matches the enzyme to the products? enzyme products A lipase amino acids only B lipase glycerol and fatty acids C prote…Question 10: What are the correct substrate and products for lipase? substrate products A fat amino acids B fat fatty acids and glycerol C protein amino…Question 11: Which enzymes are secreted from the pancreas? 1 amylase 2 lipase 3 protease A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3Question 12: Some undigested food passes out of the digestive system as faeces. What is this process? A absorption B digestion C egestion D ingestionQuestion 13: Which row shows the results of mechanical digestion?

food is broken down into

smaller soluble

smaller pieces
molecules molecules

\ \ «O…3 / 13
Question 14: Protease breaks down protein. What is the protein broken down into? A amino acids B fatty acids C glycerol D starchQuestion 15: Which diagram represents the digestion of food molecules in the alimentary canal? A B C DQuestion 16: Which description of mechanical digestion is correct? A breakdown of food into smaller pieces with chemical change to the food molecules B …Question 17: Which part of the alimentary canal carries out digestion and absorption? A C B D4 / 13
Question 18: Most food molecules need to be digested to allow them to be absorbed into the blood. Which row shows the type of digestion and the change n…Question 19: The following paragraph is a description of the digestion of fats. Large pieces of fat are broken down into smaller pieces of fat by ……1…… …Question 20: The diagram shows part of the alimentary canal and associated structures. stomach bile duct X Which row correctly identifies structure X, a…5 / 13
Question 21: Which type of digestion causes the breakdown of large, insoluble molecules into small, soluble molecules? A chemical B hormonal C mechanica…Question 22: Which row is correct for chemical digestion? food enzyme substances produced A fat protease fatty acids and glycerol B fat lipase amino aci…Question 23: Which row is correct for a protease enzyme? where secreted molecule acted on end product A stomach protein amino acids B pancreas protein f…Question 24: Which row is correct for mechanical digestion? substance being broken down using product of breakdown broken down A large food molecules en…6 / 13
Question 25: The diagram shows the digestion of fat. ......1...... glycerol ......2...... and ......3...... large piece small pieces of fat of fat Which…Question 26: Which row correctly matches the type of digestion to its effect on the food particles? type of digestion makes smaller makes soluble A chem…Question 27: Where is amylase active in the alimentary canal?

stomach small intestine

v v

0 0O WwW >

v x
x v
x x7 / 13
Question 28: The diagram shows some organs of the human body. 4 1 3 2 Which two structures carry out both mechanical and chemical digestion? A 1 and 2 B…Question 29: What is the purpose of chemical digestion? A to absorb minerals including calcium and iron B to pass food out as faeces C to break down lar…Question 30: The diagram shows what happens to fat in the alimentary canal. enzyme (2) large piece (1) (3) small (4) of fat molecules Which row correctl…8 / 13
Question 31: The diagram shows starch being digested by amylase.

starch

amylase

Which row shows the digestion taking place?

chemical mechanical
A x …Question 32: What is the role of mechanical digestion? A It breaks down large food molecules into smaller molecules. B It forms new chemical compounds f…Question 33: The diagram shows a cross-section of a root hair cell. Which row describes the root hair cell and its function? animal cell or plant cell f…9 / 13
Question 34: The diagram shows the human alimentary canal and associated organs. Which organ can produce amylase, protease and lipase? A B D CQuestion 35: The diagram represents the enzyme amylase and the products of digestion by amylase. amylase X Y What are products X and Y? X Y A amino acid…Question 36: Which process produces food molecules that are small enough to be absorbed? A chemical digestion B egestion C ingestion D mechanical digest…10 / 13
Question 37: Chemical digestion starts in the mouth and continues throughout the length of the alimentary canal. What is a sequence of three organs in t…Question 38: Chemical digestion produces small, soluble molecules. For which process is chemical digestion necessary? A absorption B egestion C excretio…Question 39: The diagram shows part of the human digestive system. stomach bile duct leading from gall bladder X Which row identifies structure X, an en…Question 40: What is the purpose of physical digestion? A break down food into smaller pieces B break down insoluble food into soluble molecules C chang…11 / 13
Question 41: Chemical digestion and physical digestion happen in various parts of the alimentary canal and associated organs. In which organ do both pro…Question 42: A test-tube is used to model the effect of protease on a protein suspension in the stomach. test-tube protease and protein suspension at 37…Question 43: A person eats some bread which contains starch. Which row shows where the chemical digestion of the starch starts and finishes? starts fini…Question 44: Which description of physical digestion is correct? A the breakdown of food into smaller pieces with a chemical change to the food molecule…12 / 13
Question 45: The diagram shows the alimentary canal and associated organs. Which structure has the correct name and function? A small intestine produces…Question 46: Which statement about lipase is correct? A It is secreted into the colon and breaks down fats and oils. B It is secreted into the small int…13 / 13

Mark scheme46 answers

Answers below. Sit the paper first if you are practising.

Pastlit

Science - Combined 0653 · Digestion — Paper 2

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1A1
2D1
3A1
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7C1
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9B1
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15A1
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17B1
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19C1
20B1
21A1
22D1
23A1
24D1
25D1
26B1
27C1
28B1
29C1
30C1
31C1
32C1
33D1
34C1
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Another paper, or another topic

All of Human nutrition

Questions as text

Q1 · Enzymes are used in digestion to break down larger molecules into smaller molecules 0653/22 Oct/Nov 2018

3 Enzymes are used in digestion to break down larger molecules into smaller molecules. Which row matches the large molecules with the small molecules they are broken down into? large molecules small molecules A fat glycerol and fatty acids B glycogen glycerol and amino acids C protein simple sugars D starch amino acids

1 marks

Answer: A

This question in 0653/22 Oct/Nov 2018

Q2 · What is defined as the breakdown of food into smaller pieces, without chemically changing… 0653/21 May/June 2019

3 What is defined as the breakdown of food into smaller pieces, without chemically changing the molecules? A absorption B chemical digestion C egestion D mechanical digestion

1 marks

Answer: D

This question in 0653/21 May/June 2019

Q3 · The diagram shows an experiment at the start and one hour later 0653/21 May/June 2019

4 The diagram shows an experiment at the start and one hour later. beaker water water and partially permeable simple sugars membrane starch solution plus Q start of experiment one hour later What is Q? A amylase B lipase C protease D water

1 marks

Answer: A

This question in 0653/21 May/June 2019

Q4 · What is the purpose of mechanical digestion? 0653/22 May/June 2019

4 What is the purpose of mechanical digestion? A to break down food into smaller pieces B to break down insoluble foods into soluble particles C to change food so that it can be absorbed into the blood D to digest insoluble food components using enzymes

1 marks

Answer: A

This question in 0653/22 May/June 2019

Q5 · 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed 0653/22 Oct/Nov 2019

4 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed. Food tests are carried out immediately after mixing and again after an hour. The results of the tests are shown in the table. colour of solution colour of solution test reagent after mixing after one hour Benedict’s solution blue orange iodine solution blue / black brown What is substance X? A amylase B protease C lipase D sugar

1 marks

Answer: A

This question in 0653/22 Oct/Nov 2019

Q6 · 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed 0653/23 Oct/Nov 2019

4 1 cm³ of substance X is added to 10 cm³ starch suspension and mixed. Food tests are carried out immediately after mixing and again after an hour. The results of the tests are shown in the table. colour of solution colour of solution test reagent after mixing after one hour Benedict’s solution blue orange iodine solution blue / black brown What is substance X? A amylase B protease C lipase D sugar

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2019

Q7 · Which are absorbed from the alimentary canal into the blood? 0653/23 Oct/Nov 2019

7 Which are absorbed from the alimentary canal into the blood? 1 fibre 2 glucose 3 vitamin C A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2019

Q8 · Animals break down large, insoluble molecules into small, soluble molecules in the… 0653/22 Feb/March 2020

4 Animals break down large, insoluble molecules into small, soluble molecules in the alimentary canal. What is this process? A chemical digestion B chemical ingestion C mechanical digestion D mechanical ingestion

1 marks

Answer: A

This question in 0653/22 Feb/March 2020

Q9 · Which row correctly matches the enzyme to the products? 0653/21 May/June 2020

4 Which row correctly matches the enzyme to the products? enzyme products A lipase amino acids only B lipase glycerol and fatty acids C protease fatty acids only D protease glycerol and amino acids

1 marks

Answer: B

This question in 0653/21 May/June 2020

Q10 · What are the correct substrate and products for lipase? 0653/22 May/June 2020

5 What are the correct substrate and products for lipase? substrate products A fat amino acids B fat fatty acids and glycerol C protein amino acids D protein fatty acids and glycerol

1 marks

Answer: B

This question in 0653/22 May/June 2020

Q11 · Which enzymes are secreted from the pancreas? 0653/21 Oct/Nov 2020

6 Which enzymes are secreted from the pancreas? 1 amylase 2 lipase 3 protease A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2020

Q12 · Some undigested food passes out of the digestive system as faeces 0653/22 Oct/Nov 2020

3 Some undigested food passes out of the digestive system as faeces. What is this process? A absorption B digestion C egestion D ingestion

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2020

Q13 · Which row shows the results of mechanical digestion? 0653/23 Oct/Nov 2020

3 Which row shows the results of mechanical digestion? food is broken down into smaller soluble smaller pieces molecules molecules \ \ «Ox < « x ae.

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2020

Q14 · Protease breaks down protein 0653/23 Oct/Nov 2020

4 Protease breaks down protein. What is the protein broken down into? A amino acids B fatty acids C glycerol D starch

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2020

Q15 · Which diagram represents the digestion of food molecules in the alimentary canal? 0653/22 Feb/March 2021

7 Which diagram represents the digestion of food molecules in the alimentary canal? A B C D

1 marks

Answer: A

This question in 0653/22 Feb/March 2021

Q16 · Which description of mechanical digestion is correct? 0653/21 May/June 2021

5 Which description of mechanical digestion is correct? A breakdown of food into smaller pieces with chemical change to the food molecules B breakdown of food into smaller pieces without chemical change to the food molecules C breakdown of large insoluble food molecules into small soluble food molecules D breakdown of large soluble food molecules into small soluble food molecules

1 marks

Answer: B

This question in 0653/21 May/June 2021

Q17 · Which part of the alimentary canal carries out digestion and absorption? 0653/22 May/June 2021

6 Which part of the alimentary canal carries out digestion and absorption? A C B D

1 marks

Answer: B

This question in 0653/22 May/June 2021

Q18 · Most food molecules need to be digested to allow them to be absorbed into the blood 0653/23 May/June 2021

6 Most food molecules need to be digested to allow them to be absorbed into the blood. Which row shows the type of digestion and the change needed to allow absorption to happen? type of digestion change to food molecules A chemical large molecules to small, insoluble molecules B chemical large molecules to small, soluble molecules C mechanical large molecules to small, soluble molecules D mechanical large molecules to small, insoluble molecules

1 marks

Answer: B

This question in 0653/23 May/June 2021

Q19 · The following paragraph is a description of the digestion of fats 0653/21 Oct/Nov 2021

6 The following paragraph is a description of the digestion of fats. Large pieces of fat are broken down into smaller pieces of fat by ……1…… digestion. These smaller pieces of fat can then be broken down by the enzyme ……2…… . This is ……3…… digestion. During this process, the larger molecules are broken down into smaller, ……4…… molecules. Which row correctly completes gaps 1, 2, 3 and 4? 1 2 3 4 A chemical lipase mechanical soluble B chemical protease mechanical insoluble C mechanical lipase chemical soluble D mechanical protease chemical insoluble

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2021

Q20 · The diagram shows part of the alimentary canal and associated structures 0653/22 Oct/Nov 2021

7 The diagram shows part of the alimentary canal and associated structures. stomach bile duct X Which row correctly identifies structure X, an enzyme secreted by structure X and the action of this enzyme? structure X enzyme action of enzyme A liver amylase converts proteins to amino acids B pancreas amylase converts starch to simple sugars C liver protease converts proteins to amino acids D pancreas protease converts starch to simple sugars

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2021

Q21 · Which type of digestion causes the breakdown of large, insoluble molecules into small… 0653/23 Oct/Nov 2021

6 Which type of digestion causes the breakdown of large, insoluble molecules into small, soluble molecules? A chemical B hormonal C mechanical D physical

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2021

Q22 · Which row is correct for chemical digestion? 0653/22 Feb/March 2022

5 Which row is correct for chemical digestion? food enzyme substances produced A fat protease fatty acids and glycerol B fat lipase amino acids C protein lipase fatty acids and glycerol D protein protease amino acids

1 marks

Answer: D

This question in 0653/22 Feb/March 2022

Q23 · Which row is correct for a protease enzyme? 0653/21 May/June 2022

5 Which row is correct for a protease enzyme? where secreted molecule acted on end product A stomach protein amino acids B pancreas protein fatty acid and glycerol C stomach lipids amino acids D pancreas lipids fatty acid and glycerol

1 marks

Answer: A

This question in 0653/21 May/June 2022

Q24 · Which row is correct for mechanical digestion? 0653/22 May/June 2022

5 Which row is correct for mechanical digestion? substance being broken down using product of breakdown broken down A large food molecules enzymes small pieces of food B large food molecules teeth small food molecules C large pieces of food enzymes small food molecules D large pieces of food teeth small pieces of food

1 marks

Answer: D

This question in 0653/22 May/June 2022

Q25 · The diagram shows the digestion of fat 0653/23 May/June 2022

6 The diagram shows the digestion of fat. … 1 … glycerol … 2 … and … 3 … large piece small pieces of fat of fat Which row completes gaps 1, 2 and 3 in the diagram? 1 2 3 A chemical digestion chemical digestion amino acids B chemical digestion mechanical digestion fatty acids C mechanical digestion mechanical digestion amino acids D mechanical digestion chemical digestion fatty acids

1 marks

Answer: D

This question in 0653/23 May/June 2022

Q26 · Which row correctly matches the type of digestion to its effect on the food particles? 0653/21 Oct/Nov 2022

5 Which row correctly matches the type of digestion to its effect on the food particles? type of digestion makes smaller makes soluble A chemical no yes B chemical yes yes C mechanical no no D mechanical yes yes

1 marks

Answer: B

This question in 0653/21 Oct/Nov 2022

Q27 · Where is amylase active in the alimentary canal? 0653/22 Oct/Nov 2022

6 Where is amylase active in the alimentary canal? stomach small intestine v v 0 0O WwW > v x x v x x

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2022

Q28 · The diagram shows some organs of the human body 0653/22 Feb/March 2023

4 The diagram shows some organs of the human body. 4 1 3 2 Which two structures carry out both mechanical and chemical digestion? A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4

1 marks

Answer: B

This question in 0653/22 Feb/March 2023

Q29 · What is the purpose of chemical digestion? 0653/21 May/June 2023

6 What is the purpose of chemical digestion? A to absorb minerals including calcium and iron B to pass food out as faeces C to break down large nutrient molecules into smaller molecules D to secrete enzymes

1 marks

Answer: C

This question in 0653/21 May/June 2023

Q30 · The diagram shows what happens to fat in the alimentary canal 0653/21 Oct/Nov 2023

6 The diagram shows what happens to fat in the alimentary canal. enzyme (2) large piece (1) (3) small (4) of fat molecules Which row correctly identifies 1, 2, 3 and 4? 1 2 3 4 A chemical lipase mechanical soluble digestion digestion B chemical protease ingestion insoluble digestion C mechanical lipase chemical soluble digestion digestion D mechanical protease ingestion insoluble digestion

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2023

Q31 · The diagram shows starch being digested by amylase 0653/22 Oct/Nov 2023

5 The diagram shows starch being digested by amylase. starch amylase Which row shows the digestion taking place? chemical mechanical A x x B x v Cc v x D Jv v é % 00 *e $ é “ & ;

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2023

Q32 · What is the role of mechanical digestion? 0653/23 Oct/Nov 2023

6 What is the role of mechanical digestion? A It breaks down large food molecules into smaller molecules. B It forms new chemical compounds for the body to utilise. C It breaks down large pieces of food into smaller pieces. D It makes the food particles soluble for better absorption.

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2023

Q33 · The diagram shows a cross-section of a root hair cell 0653/22 Feb/March 2024

2 The diagram shows a cross-section of a root hair cell. Which row describes the root hair cell and its function? animal cell or plant cell function A animal cell water and glucose absorption B animal cell water and ion absorption C plant cell water and glucose absorption D plant cell water and ion absorption

1 marks

Answer: D

This question in 0653/22 Feb/March 2024

Q34 · The diagram shows the human alimentary canal and associated organs 0653/22 Feb/March 2024

6 The diagram shows the human alimentary canal and associated organs. Which organ can produce amylase, protease and lipase? A B D C

1 marks

Answer: C

This question in 0653/22 Feb/March 2024

Q35 · The diagram represents the enzyme amylase and the products of digestion by amylase 0653/21 May/June 2024

2 The diagram represents the enzyme amylase and the products of digestion by amylase. amylase X Y What are products X and Y? X Y A amino acid amino acid B fatty acid glycerol C glycerol fatty acid D simple sugar simple sugar

1 marks

Answer: D

This question in 0653/21 May/June 2024

Q36 · Which process produces food molecules that are small enough to be absorbed? 0653/21 May/June 2024

4 Which process produces food molecules that are small enough to be absorbed? A chemical digestion B egestion C ingestion D mechanical digestion

1 marks

Answer: A

This question in 0653/21 May/June 2024

Q37 · Chemical digestion starts in the mouth and continues throughout the length of the… 0653/22 May/June 2024

6 Chemical digestion starts in the mouth and continues throughout the length of the alimentary canal. What is a sequence of three organs in the alimentary canal where chemical digestion occurs? A oesophagus  gall bladder  liver B oesophagus  stomach  small intestine C small intestine  gall bladder  large intestine D small intestine  stomach  oesophagus

1 marks

Answer: B

This question in 0653/22 May/June 2024

Q38 · Chemical digestion produces small, soluble molecules 0653/23 Oct/Nov 2024

5 Chemical digestion produces small, soluble molecules. For which process is chemical digestion necessary? A absorption B egestion C excretion D ingestion

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2024

Q39 · The diagram shows part of the human digestive system 0653/22 Feb/March 2025

6 The diagram shows part of the human digestive system. stomach bile duct leading from gall bladder X Which row identifies structure X, an enzyme secreted by structure X and the action of this enzyme? structure X enzyme action of enzyme A liver amylase converts proteins to amino acids B pancreas amylase converts starch to simple sugars C liver protease converts proteins to amino acids D pancreas protease converts starch to simple sugars

1 marks

Answer: B

This question in 0653/22 Feb/March 2025

Q40 · What is the purpose of physical digestion? 0653/21 May/June 2025

6 What is the purpose of physical digestion? A break down food into smaller pieces B break down insoluble food into soluble molecules C change food so that it can be absorbed into the blood D digest insoluble food molecules using enzymes

1 marks

Answer: A

This question in 0653/21 May/June 2025

Q41 · Chemical digestion and physical digestion happen in various parts of the alimentary canal… 0653/23 May/June 2025

8 Chemical digestion and physical digestion happen in various parts of the alimentary canal and associated organs. In which organ do both processes happen? A liver B mouth C oesophagus D pancreas

1 marks

Answer: B

This question in 0653/23 May/June 2025

Q42 · A test-tube is used to model the effect of protease on a protein suspension in the stomach 0653/23 May/June 2025

9 A test-tube is used to model the effect of protease on a protein suspension in the stomach. test-tube protease and protein suspension at 37 °C What should be added to the test-tube to provide the optimum conditions for the digestion of protein? A amylase B bacteria C hydrochloric acid D lipase

1 marks

Answer: C

This question in 0653/23 May/June 2025

Q43 · A person eats some bread which contains starch 0653/21 Oct/Nov 2025

6 A person eats some bread which contains starch. Which row shows where the chemical digestion of the starch starts and finishes? starts finishes A mouth small intestine B mouth large intestine C stomach small intestine D stomach large intestine

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2025

Q44 · Which description of physical digestion is correct? 0653/22 Oct/Nov 2025

7 Which description of physical digestion is correct? A the breakdown of food into smaller pieces with a chemical change to the food molecules B the breakdown of food into smaller pieces without a chemical change to the food molecules C the breakdown of large insoluble food molecules into small soluble food molecules D the breakdown of large soluble food molecules into small soluble food molecules

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2025

Q45 · The diagram shows the alimentary canal and associated organs 0653/22 Oct/Nov 2025

8 The diagram shows the alimentary canal and associated organs. Which structure has the correct name and function? A small intestine produces amylase B gall bladder produces protease C stomach kills bacteria D large intestine absorbs amino acids

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2025

Q46 · Which statement about lipase is correct? 0653/23 Oct/Nov 2025

6 Which statement about lipase is correct? A It is secreted into the colon and breaks down fats and oils. B It is secreted into the small intestine and breaks down fats and oils. C It is secreted into the small intestine and breaks down fatty acids into glycerol. D It is secreted into the stomach and breaks down glycerol into fatty acids.

1 marks

Answer: B

This question in 0653/23 Oct/Nov 2025