TopicalSciences - Co-ordinated (Double) 0654Coordination and responseHormonesPaper 1

Hormones — Paper 1 · IGCSE Sciences - Co-ordinated (Double) 0654

B13.2· 40 questions · 40 marks · 48 min · 2006–2025· Multiple choice

Every Cambridge IGCSE Sciences - Co-ordinated (Double) Paper 1 question on hormones, laid out as 11 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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Questions11 pages

Question 1: The graphs show changes in the amount of sugar in the blood after a person has eaten a sugary meal. Which graph shows changes in the amount…Question 2: The diagram shows the male reproductive system. In which structure are hormones produced that control adolescence? A B C D1 / 11
Question 3: The graph shows changes in the concentration of sugar in the blood after a person has eaten a spoonful of honey. Q R concentration P S of s…Question 4: The diagram shows the male reproductive system. In which structure are the hormones that control adolescence produced? A B C DQuestion 5: What would be the effect on the blood of an over-secretion of insulin? A high levels of glucose B high levels of urea C low levels of gluco…2 / 11
Question 6: What would be the effect on the blood of an over-secretion of insulin? A high levels of glucose B high levels of urea C low levels of gluco…Question 7: What is a function of adrenaline? A to increase the concentration of blood sugar B to raise the level of oxygen in the blood C to reduce th…Question 8: What is a function of adrenaline? A to increase the concentration of blood sugar B to raise the level of oxygen in the blood C to reduce th…Question 9: Which are target organs for adrenaline?

heart liver

x x

loom >

x v
v x
v vQuestion 10: The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C B3 / 11
Question 11: The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C BQuestion 12: What is the effect of adrenaline? blood glucose rate of concentration heart beat A decrease decrease B decrease increase C increase decreas…Question 13: The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C B4 / 11
Question 14: What is a characteristic of human hormones? A destroyed by endocrine glands B made by target organs C produced in the liver D transported i…Question 15: What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decrease…Question 16: What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decrease…Question 17: What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decrease…Question 18: A frightened animal may need to run away suddenly. Which substance is released to stimulate an increase in blood glucose concentration? A a…5 / 11
Question 19: Which substance causes an increase in blood glucose concentration? A adrenaline B insulin C oxygen D vitamin CQuestion 20: A boy is frightened, and his heart rate rises and his pupils dilate. Following this response, which blood vessel carries the adrenaline to …Question 21: The graph shows the pulse rate over a period of time. At which point was adrenaline released into the blood? pulse rate A B C D timeQuestion 22: What is the effect of adrenaline on the body? pulse rate size of pupil A decreased large B decreased small C increased small D increased la…6 / 11
Question 23: A student is in a dangerous situation and adrenaline is released into the blood. The table shows changes to pulse rate, breathing rate and …Question 24: A student is in a dangerous situation and adrenaline is released into the blood. The table shows changes to pulse rate, breathing rate and …Question 25: Adrenaline is injected into the blood to treat some medical conditions. What would happen as a result of injecting adrenaline? 1 narrowing …Question 26: A student wrote some notes about hormones. She wrote: ‘A hormone is produced by a ……1…… . It is transported in the blood ……2……. . It alters…7 / 11
Question 27: What is a hormone? A a chemical substance, produced by a gland, which alters the activity of target organs B a protein that acts as a biolo…Question 28: What is a hormone? A a chemical substance, produced by a gland, which alters the activity of target organs B a protein that acts as a biolo…Question 29: Which row shows a person’s response to a ‘fight or flight’ situation? breathing rate pulse rate / breaths per minute / beats per minute A 1…Question 30: The graph shows the pulse rate over a period of time. At which point is adrenaline released into the blood? pulse rate A B C D timeQuestion 31: What are the effects of adrenaline? breathing rate pulse rate pupil size A decrease decrease widens B decrease increase narrows C increase …8 / 11
Question 32: One response to a frightening situation is an increase in heart rate caused by the release of adrenaline. Which statement about adrenaline …Question 33: The graphs show the pupil diameter and heart rate of a person over a period of 30 minutes. The person was given an unexpected shock at one …Question 34: Which row about hormones is correct? means of transport where produced site of action A alimentary canal glands target organs B alimentary …9 / 11
Question 35: Which row about hormones is correct? means of transport where produced site of action A alimentary canal glands target organs B alimentary …Question 36: Which activities increase the secretion of adrenaline in the human body?

running to relaxing in Wrightentag
catch a bus the sun horror fil…Question 37: Which activities increase the secretion of adrenaline in the human body?

running to relaxing in Wrightentag
catch a bus the sun horror fil…Question 38: Which row shows effects of adrenaline? heart rate pupil diameter A increases increases B increases no effect C decreases increases D no eff…Question 39: Which row shows the effect of adrenaline? effect on effect on pupil diameter heart rate A narrows decreases B widens decreases C narrows in…10 / 11
Question 40: Which row shows the effect of adrenaline? effect on effect on pupil diameter heart rate A narrows decreases B widens decreases C narrows in…11 / 11

Mark scheme40 answers

Answers below. Sit the paper first if you are practising.

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Sciences - Co-ordinated (Double) 0654 · Hormones — Paper 1

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1C1
2D1
3A1
4D1
5C1
6C1
7A1
8A1
9D1
10B1
11B1
12D1
13B1
14D1
15D1
16D1
17D1
18A1
19A1
20A1
21A1
22D1
23C1
24C1
25C1
26B1
27A1
28A1
29D1
30A1
31D1
32C1
33D1
34C1
35C1
36A1
37A1
38A1
39D1
40D1
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Another paper, or another topic

All of Coordination and response

Questions as text

Q1 · The graphs show changes in the amount of sugar in the blood after a person has eaten a… 0654/11 May/June 2006

9 The graphs show changes in the amount of sugar in the blood after a person has eaten a sugary meal. Which graph shows changes in the amount of blood sugar of a person with untreated diabetes? A B blood sugar blood sugar level / level / arbitrary units arbitrary units 1 1 meal eaten time/ hours meal eaten time/ hours C D blood sugar blood sugar level / level / arbitrary units arbitrary units 1 1 meal eaten time/ hours meal eaten time/ hours

1 marks

Answer: C

This question in 0654/11 May/June 2006

Q2 · The diagram shows the male reproductive system 0654/11 Oct/Nov 2006

10 The diagram shows the male reproductive system. In which structure are hormones produced that control adolescence? A B C D

1 marks

Answer: D

This question in 0654/11 Oct/Nov 2006

Q3 · The graph shows changes in the concentration of sugar in the blood after a person has… 0654/11 May/June 2008

9 The graph shows changes in the concentration of sugar in the blood after a person has eaten a spoonful of honey. Q R concentration P S of sugar time honey eaten At which points on the curve is insulin being produced? P Q R S A no yes yes no B yes no no no C no yes no yes D yes yes yes no

1 marks

Answer: A

This question in 0654/11 May/June 2008

Q4 · The diagram shows the male reproductive system 0654/11 May/June 2009

10 The diagram shows the male reproductive system. In which structure are the hormones that control adolescence produced? A B C D

1 marks

Answer: D

This question in 0654/11 May/June 2009

Q5 · What would be the effect on the blood of an over-secretion of insulin? 0654/11 May/June 2010

7 What would be the effect on the blood of an over-secretion of insulin? A high levels of glucose B high levels of urea C low levels of glucose D low levels of urea

1 marks

Answer: C

This question in 0654/11 May/June 2010

Q6 · What would be the effect on the blood of an over-secretion of insulin? 0654/12 May/June 2010

9 What would be the effect on the blood of an over-secretion of insulin? A high levels of glucose B high levels of urea C low levels of glucose D low levels of urea

1 marks

Answer: C

This question in 0654/12 May/June 2010

Q7 · What is a function of adrenaline? 0654/11 May/June 2014

8 What is a function of adrenaline? A to increase the concentration of blood sugar B to raise the level of oxygen in the blood C to reduce the rate of heart beat D to remove urea from the blood

1 marks

Answer: A

This question in 0654/11 May/June 2014

Q8 · What is a function of adrenaline? 0654/13 May/June 2014

9 What is a function of adrenaline? A to increase the concentration of blood sugar B to raise the level of oxygen in the blood C to reduce the rate of heart beat D to remove urea from the blood

1 marks

Answer: A

This question in 0654/13 May/June 2014

Q9 · Which are target organs for adrenaline? 0654/13 May/June 2015

10 Which are target organs for adrenaline? heart liver x x loom > x v v x v v

1 marks

Answer: D

This question in 0654/13 May/June 2015

Q10 · The diagram shows the male reproductive system 0654/11 Oct/Nov 2015

11 The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C B

1 marks

Answer: B

This question in 0654/11 Oct/Nov 2015

Q11 · The diagram shows the male reproductive system 0654/12 Oct/Nov 2015

10 The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C B

1 marks

Answer: B

This question in 0654/12 Oct/Nov 2015

Q12 · What is the effect of adrenaline? 0654/12 Oct/Nov 2015

11 What is the effect of adrenaline? blood glucose rate of concentration heart beat A decrease decrease B decrease increase C increase decrease D increase increase

1 marks

Answer: D

This question in 0654/12 Oct/Nov 2015

Q13 · The diagram shows the male reproductive system 0654/13 Oct/Nov 2015

10 The diagram shows the male reproductive system. Which structure produces the hormones that control adolescence? A D C B

1 marks

Answer: B

This question in 0654/13 Oct/Nov 2015

Q14 · What is a characteristic of human hormones? 0654/11 May/June 2016

10 What is a characteristic of human hormones? A destroyed by endocrine glands B made by target organs C produced in the liver D transported in blood plasma

1 marks

Answer: D

This question in 0654/11 May/June 2016

Q15 · What are the effects of adrenaline? 0654/11 Oct/Nov 2016

9 What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0654/11 Oct/Nov 2016

Q16 · What are the effects of adrenaline? 0654/12 Oct/Nov 2016

9 What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0654/12 Oct/Nov 2016

Q17 · What are the effects of adrenaline? 0654/13 Oct/Nov 2016

9 What are the effects of adrenaline? blood glucose pulse rate concentration A decreases decreases B decreases increases C increases decreases D increases increases

1 marks

Answer: D

This question in 0654/13 Oct/Nov 2016

Q18 · A frightened animal may need to run away suddenly 0654/11 May/June 2017

10 A frightened animal may need to run away suddenly. Which substance is released to stimulate an increase in blood glucose concentration? A adrenaline B haemoglobin C plasma D platelets

1 marks

Answer: A

This question in 0654/11 May/June 2017

Q19 · Which substance causes an increase in blood glucose concentration? 0654/12 Oct/Nov 2017

9 Which substance causes an increase in blood glucose concentration? A adrenaline B insulin C oxygen D vitamin C

1 marks

Answer: A

This question in 0654/12 Oct/Nov 2017

Q20 · A boy is frightened, and his heart rate rises and his pupils dilate 0654/12 Oct/Nov 2018

6 A boy is frightened, and his heart rate rises and his pupils dilate. Following this response, which blood vessel carries the adrenaline to the organ where it is destroyed? A hepatic artery B pulmonary artery C renal artery D vena cava

1 marks

Answer: A

This question in 0654/12 Oct/Nov 2018

Q21 · The graph shows the pulse rate over a period of time 0654/11 Oct/Nov 2019

9 The graph shows the pulse rate over a period of time. At which point was adrenaline released into the blood? pulse rate A B C D time

1 marks

Answer: A

This question in 0654/11 Oct/Nov 2019

Q22 · What is the effect of adrenaline on the body? 0654/12 Feb/March 2021

9 What is the effect of adrenaline on the body? pulse rate size of pupil A decreased large B decreased small C increased small D increased large

1 marks

Answer: D

This question in 0654/12 Feb/March 2021

Q23 · A student is in a dangerous situation and adrenaline is released into the blood 0654/12 May/June 2021

9 A student is in a dangerous situation and adrenaline is released into the blood. The table shows changes to pulse rate, breathing rate and pupil diameter. Which row correctly describes the effect of adrenaline? pulse rate breathing rate pupil diameter A decrease increase decrease B decrease decrease increase C increase increase increase D increase decrease decrease

1 marks

Answer: C

This question in 0654/12 May/June 2021

Q24 · A student is in a dangerous situation and adrenaline is released into the blood 0654/13 May/June 2021

9 A student is in a dangerous situation and adrenaline is released into the blood. The table shows changes to pulse rate, breathing rate and pupil diameter. Which row correctly describes the effect of adrenaline? pulse rate breathing rate pupil diameter A decrease increase decrease B decrease decrease increase C increase increase increase D increase decrease decrease

1 marks

Answer: C

This question in 0654/13 May/June 2021

Q25 · Adrenaline is injected into the blood to treat some medical conditions 0654/12 Oct/Nov 2021

9 Adrenaline is injected into the blood to treat some medical conditions. What would happen as a result of injecting adrenaline? 1 narrowing of the pupil in the eye 2 increased breathing rate 3 increased pulse rate A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

1 marks

Answer: C

This question in 0654/12 Oct/Nov 2021

Q26 · A student wrote some notes about hormones 0654/13 Oct/Nov 2021

9 A student wrote some notes about hormones. She wrote: ‘A hormone is produced by a ……1…… . It is transported in the blood ……2……. . It alters the activity of one or more ……3……. organs.’ Which row correctly completes gaps 1, 2 and 3? 1 2 3 A gland cells specific B gland plasma target C tissue cells specific D tissue plasma target

1 marks

Answer: B

This question in 0654/13 Oct/Nov 2021

Q27 · What is a hormone? 0654/12 May/June 2022

9 What is a hormone? A a chemical substance, produced by a gland, which alters the activity of target organs B a protein that acts as a biological catalyst C a thread-like structure of DNA, carrying genetic information in the form of genes D an electrical signal that travels along a nerve cell to an effector

1 marks

Answer: A

This question in 0654/12 May/June 2022

Q28 · What is a hormone? 0654/13 May/June 2022

9 What is a hormone? A a chemical substance, produced by a gland, which alters the activity of target organs B a protein that acts as a biological catalyst C a thread-like structure of DNA, carrying genetic information in the form of genes D an electrical signal that travels along a nerve cell to an effector

1 marks

Answer: A

This question in 0654/13 May/June 2022

Q29 · Which row shows a person’s response to a ‘fight or flight’ situation? 0654/12 Oct/Nov 2022

9 Which row shows a person’s response to a ‘fight or flight’ situation? breathing rate pulse rate / breaths per minute / beats per minute A 12 70 B 12 140 C 18 70 D 18 140

1 marks

Answer: D

This question in 0654/12 Oct/Nov 2022

Q30 · The graph shows the pulse rate over a period of time 0654/12 Feb/March 2023

9 The graph shows the pulse rate over a period of time. At which point is adrenaline released into the blood? pulse rate A B C D time

1 marks

Answer: A

This question in 0654/12 Feb/March 2023

Q31 · What are the effects of adrenaline? 0654/11 May/June 2023

9 What are the effects of adrenaline? breathing rate pulse rate pupil size A decrease decrease widens B decrease increase narrows C increase decrease narrows D increase increase widens

1 marks

Answer: D

This question in 0654/11 May/June 2023

Q32 · One response to a frightening situation is an increase in heart rate caused by the… 0654/11 Oct/Nov 2023

9 One response to a frightening situation is an increase in heart rate caused by the release of adrenaline. Which statement about adrenaline is correct? A It is an enzyme produced by an organ and travels in the blood to the heart. B It is an enzyme produced by an organ and travels down a nerve to the brain. C It is a hormone produced by a gland and travels in the blood to the heart. D It is a hormone produced by a gland and travels down a nerve to the brain.

1 marks

Answer: C

This question in 0654/11 Oct/Nov 2023

Q33 · The graphs show the pupil diameter and heart rate of a person over a period of 30 minutes 0654/13 Oct/Nov 2023

9 The graphs show the pupil diameter and heart rate of a person over a period of 30 minutes. The person was given an unexpected shock at one point during the 30 minutes. pupil diameter 0 5 10 15 20 25 30 time / min heart rate 0 5 10 15 20 25 30 time / min At which time did the person experience a shock causing them to release adrenaline? A 5 minutes B 10 minutes C 15 minutes D 25 minutes

1 marks

Answer: D

This question in 0654/13 Oct/Nov 2023

Q34 · Which row about hormones is correct? 0654/12 May/June 2024

9 Which row about hormones is correct? means of transport where produced site of action A alimentary canal glands target organs B alimentary canal organs all organs C blood glands target organs D blood organs all organs

1 marks

Answer: C

This question in 0654/12 May/June 2024

Q35 · Which row about hormones is correct? 0654/13 May/June 2024

9 Which row about hormones is correct? means of transport where produced site of action A alimentary canal glands target organs B alimentary canal organs all organs C blood glands target organs D blood organs all organs

1 marks

Answer: C

This question in 0654/13 May/June 2024

Q36 · Which activities increase the secretion of adrenaline in the human body? 0654/12 Oct/Nov 2024

9 Which activities increase the secretion of adrenaline in the human body? running to relaxing in Wrightentag catch a bus the sun horror film A v x v B x v v Cc J x x D x v x

1 marks

Answer: A

This question in 0654/12 Oct/Nov 2024

Q37 · Which activities increase the secretion of adrenaline in the human body? 0654/13 Oct/Nov 2024

9 Which activities increase the secretion of adrenaline in the human body? running to relaxing in Wrightentag catch a bus the sun horror film A v x v B x v v Cc J x x D x v x

1 marks

Answer: A

This question in 0654/13 Oct/Nov 2024

Q38 · Which row shows effects of adrenaline? 0654/11 May/June 2025

11 Which row shows effects of adrenaline? heart rate pupil diameter A increases increases B increases no effect C decreases increases D no effect increases

1 marks

Answer: A

This question in 0654/11 May/June 2025

Q39 · Which row shows the effect of adrenaline? 0654/12 Oct/Nov 2025

9 Which row shows the effect of adrenaline? effect on effect on pupil diameter heart rate A narrows decreases B widens decreases C narrows increases D widens increases

1 marks

Answer: D

This question in 0654/12 Oct/Nov 2025

Q40 · Which row shows the effect of adrenaline? 0654/13 Oct/Nov 2025

9 Which row shows the effect of adrenaline? effect on effect on pupil diameter heart rate A narrows decreases B widens decreases C narrows increases D widens increases

1 marks

Answer: D

This question in 0654/13 Oct/Nov 2025