Digestive system — Paper 2 · IGCSE Science - Combined 0653

2 The graph shows the effect of pH on the activity of four different enzymes. Which enzyme is most active in the stomach? D B enzyme A activity C 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 pH

1 marks

Answer: A

This question in 0653/22 Feb/March 2017

5 Which row matches the part of the alimentary canal to its function? part of the alimentary canal function of part A colon absorption of digested food B ileum egestion C mouth mechanical digestion D pancreas production of bile

1 marks

Answer: C

This question in 0653/23 May/June 2017

6 In which order does food pass through parts of the alimentary canal? A oesophagus → colon → small intestine B small intestine → oesophagus → rectum C small intestine → rectum → anus D stomach → colon → small intestine

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2017

4 In which order does food pass through parts of the alimentary canal? A oesophagus → colon → small intestine B small intestine → oesophagus → rectum C small intestine → rectum → anus D stomach → colon → small intestine

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2017

5 In which order does food pass through parts of the alimentary canal? A oesophagus → colon → small intestine B small intestine → oesophagus → rectum C small intestine → rectum → anus D stomach → colon → small intestine

1 marks

Answer: C

This question in 0653/23 Oct/Nov 2017

6 The diagram shows the alimentary canal. Which label shows where bile is stored? A B C D

1 marks

Answer: B

This question in 0653/22 Feb/March 2018

6 The diagram shows part of the human alimentary canal. Where is bile made? A D B C

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2018

5 The diagram shows the alimentary canal and some associated organs. In which structure is bile stored? A B C D

1 marks

Answer: B

This question in 0653/23 May/June 2019

6 Which enzymes are secreted from the pancreas? 1 amylase 2 lipase 3 protease A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

1 marks

Answer: D

This question in 0653/21 Oct/Nov 2020

4 What is a function of the hydrochloric acid produced in the stomach? A to help absorption of all food in the stomach B to kill bacteria in the ingested food C to prevent chemical digestion D to prevent the stomach contents being too acidic

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2020

6 Most food molecules need to be digested to allow them to be absorbed into the blood. Which row shows the type of digestion and the change needed to allow absorption to happen? type of digestion change to food molecules A chemical large molecules to small, insoluble molecules B chemical large molecules to small, soluble molecules C mechanical large molecules to small, soluble molecules D mechanical large molecules to small, insoluble molecules

1 marks

Answer: B

This question in 0653/23 May/June 2021

7 The diagram shows part of the alimentary canal and associated structures. stomach bile duct X Which row correctly identifies structure X, an enzyme secreted by structure X and the action of this enzyme? structure X enzyme action of enzyme A liver amylase converts proteins to amino acids B pancreas amylase converts starch to simple sugars C liver protease converts proteins to amino acids D pancreas protease converts starch to simple sugars

1 marks

Answer: B

This question in 0653/22 Oct/Nov 2021

4 The diagram shows some organs of the human body. 4 1 3 2 Which two structures carry out both mechanical and chemical digestion? A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4

1 marks

Answer: B

This question in 0653/22 Feb/March 2023

6 In which order does food pass through parts of the alimentary canal? A oesophagus  anus  large intestine B small intestine  oesophagus  stomach C small intestine  large intestine  anus D stomach  large intestine  small intestine

1 marks

Answer: C

This question in 0653/22 May/June 2023

5 Which row matches the part of the alimentary canal to its function? part of the function of part alimentary canal A anus absorption B oesophagus digestion C mouth ingestion D small intestines egestion

1 marks

Answer: C

This question in 0653/23 May/June 2023

6 The diagram shows what happens to fat in the alimentary canal. enzyme (2) large piece (1) (3) small (4) of fat molecules Which row correctly identifies 1, 2, 3 and 4? 1 2 3 4 A chemical lipase mechanical soluble digestion digestion B chemical protease ingestion insoluble digestion C mechanical lipase chemical soluble digestion digestion D mechanical protease ingestion insoluble digestion

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2023

6 The diagram shows the human alimentary canal and associated organs. Which organ can produce amylase, protease and lipase? A B D C

1 marks

Answer: C

This question in 0653/22 Feb/March 2024

6 Chemical digestion starts in the mouth and continues throughout the length of the alimentary canal. What is a sequence of three organs in the alimentary canal where chemical digestion occurs? A oesophagus  gall bladder  liver B oesophagus  stomach  small intestine C small intestine  gall bladder  large intestine D small intestine  stomach  oesophagus

1 marks

Answer: B

This question in 0653/22 May/June 2024

6 Which process is defined as the taking of substances, for example food and drink, into the body through the mouth? A absorption B digestion C egestion D ingestion

1 marks

Answer: D

This question in 0653/23 May/June 2024

5 The diagram shows the human alimentary canal. 1 2 3 Where do egestion and ingestion occur? egestion ingestion A 1 3 B 2 3 C 3 1 D 3 2

1 marks

Answer: C

This question in 0653/21 Oct/Nov 2024

6 A list of enzymes and a diagram of some human organs are shown. 1 amylase 2 protease 3 lipase X Which enzymes are secreted by the organ labelled X? A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2024

5 Chemical digestion produces small, soluble molecules. For which process is chemical digestion necessary? A absorption B egestion C excretion D ingestion

1 marks

Answer: A

This question in 0653/23 Oct/Nov 2024

6 The diagram shows part of the human digestive system. stomach bile duct leading from gall bladder X Which row identifies structure X, an enzyme secreted by structure X and the action of this enzyme? structure X enzyme action of enzyme A liver amylase converts proteins to amino acids B pancreas amylase converts starch to simple sugars C liver protease converts proteins to amino acids D pancreas protease converts starch to simple sugars

1 marks

Answer: B

This question in 0653/22 Feb/March 2025

7 The diagram shows the human alimentary canal and other organs. Which label shows where glycerol is absorbed? A B C D

1 marks

Answer: C

This question in 0653/21 May/June 2025

8 What is a function of hydrochloric acid in the stomach? A to help absorption of all food in the stomach B to kill microorganisms in the ingested food C to prevent chemical digestion D to prevent the stomach contents being too acidic

1 marks

Answer: B

This question in 0653/22 May/June 2025

8 Chemical digestion and physical digestion happen in various parts of the alimentary canal and associated organs. In which organ do both processes happen? A liver B mouth C oesophagus D pancreas

1 marks

Answer: B

This question in 0653/23 May/June 2025

6 A person eats some bread which contains starch. Which row shows where the chemical digestion of the starch starts and finishes? starts finishes A mouth small intestine B mouth large intestine C stomach small intestine D stomach large intestine

1 marks

Answer: A

This question in 0653/21 Oct/Nov 2025

8 The diagram shows the alimentary canal and associated organs. Which structure has the correct name and function? A small intestine produces amylase B gall bladder produces protease C stomach kills bacteria D large intestine absorbs amino acids

1 marks

Answer: C

This question in 0653/22 Oct/Nov 2025

6 Which statement about lipase is correct? A It is secreted into the colon and breaks down fats and oils. B It is secreted into the small intestine and breaks down fats and oils. C It is secreted into the small intestine and breaks down fatty acids into glycerol. D It is secreted into the stomach and breaks down glycerol into fatty acids.

1 marks

Answer: B

This question in 0653/23 Oct/Nov 2025