B15.4· 23 questions · 23 marks · 28 min · 2017–2025· Multiple choice
Every Cambridge IGCSE Sciences - Co-ordinated (Double) Paper 2 question on sexual reproduction in humans, laid out as 6 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.





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6 / 6Answers below. Sit the paper first if you are practising.
Pastlit
Sciences - Co-ordinated (Double) 0654 · Sexual reproduction in humans — Paper 2
IGCSE · topical answer key — answer key (teacher use)
Question
Answer
Marks
| Question | Answer | Marks | From |
|---|---|---|---|
| 1 | C | 1 | 0654/22 May/June 2017 |
| 2 | A | 1 | 0654/21 Oct/Nov 2017 |
| 3 | A | 1 | 0654/23 Oct/Nov 2017 |
| 4 | B | 1 | 0654/21 Oct/Nov 2018 |
| 5 | B | 1 | 0654/22 May/June 2019 |
| 6 | B | 1 | 0654/21 Oct/Nov 2019 |
| 7 | B | 1 | 0654/21 Oct/Nov 2020 |
| 8 | B | 1 | 0654/22 Oct/Nov 2020 |
| 9 | B | 1 | 0654/23 Oct/Nov 2020 |
| 10 | B | 1 | 0654/22 May/June 2021 |
| 11 | D | 1 | 0654/23 May/June 2021 |
| 12 | B | 1 | 0654/22 Oct/Nov 2021 |
| 13 | B | 1 | 0654/22 Feb/March 2022 |
| 14 | A | 1 | 0654/21 Oct/Nov 2022 |
| 15 | B | 1 | 0654/21 May/June 2023 |
| 16 | B | 1 | 0654/21 Oct/Nov 2023 |
| 17 | C | 1 | 0654/22 Oct/Nov 2023 |
| 18 | C | 1 | 0654/22 Feb/March 2024 |
| 19 | D | 1 | 0654/22 May/June 2024 |
| 20 | A | 1 | 0654/23 May/June 2024 |
| 21 | B | 1 | 0654/22 Oct/Nov 2024 |
| 22 | A | 1 | 0654/22 Feb/March 2025 |
| 23 | A | 1 | 0654/23 May/June 2025 |
7 The diagram shows stages in the development of a fertilised zygote. Which stage becomes implanted in the wall of the uterus? A B C D
1 marks
Answer: C
6 The maternal blood leaving the placenta is different in composition from that arriving. What are those differences? carbon oxygen glucose dioxide A less more less B less more same C more less more D more less same
1 marks
Answer: A
6 What is meant by fertilisation? A combining of male and female nuclei B joining of male and female sex organs C movement of sperms through the uterus to an ovum D reproduction
1 marks
Answer: A
10 Kangaroos have 16 chromosomes in their skin cells. How many chromosomes are there in a kangaroo sperm cell? A 4 B 8 C 16 D 32
1 marks
Answer: B
11 Which sex chromosomes need to be present in a sperm cell to produce a male zygote? A X only B Y only C XX D XY
1 marks
Answer: B
10 During pregnancy, the placenta is used to exchange substances between the mother and the fetus. Which row is correct? substance exchanged direction A carbon dioxide mother to fetus B glucose mother to fetus C glucose fetus to mother D oxygen fetus to mother
1 marks
Answer: B
10 In human reproduction, which cells are haploid? gametes zygotes v v 0 Oo WwW > v x x v x x
1 marks
Answer: B
10 In human reproduction, which cells are haploid? gametes zygotes v v 00 WwW > v x x v x x
1 marks
Answer: B
10 In human reproduction, which cells are haploid? gametes zygotes v v 00 WwW > v x x v x x
1 marks
Answer: B
10 Which row about human gametes is correct? flagellum energy store shows gamete present present motility A female v v Jv B female Xx v x Cc male v v x D male x x v key /=yes X =no
1 marks
Answer: B
2 Which row is correct for a human sperm cell? flagellum nucleus presence of enzymes A no diploid yes B no haploid no C yes diploid no D yes haploid yes
1 marks
Answer: D
10 Which row describes the exchange of substances between a mother and her fetus in mammals? substances moving from substances moving from the mother to fetus the fetus to mother A glucose and carbon dioxide urea and oxygen B glucose and oxygen urea and carbon dioxide C urea and carbon dioxide glucose and oxygen D urea and oxygen glucose and carbon dioxide
1 marks
Answer: B
10 Which statements correctly describe the human male gamete? 1 contains enzymes 2 food stores present 3 flagellum present 4 surrounded by a jelly coating A 1 and 2 B 1 and 3 C 2 and 3 D 3 and 4
1 marks
Answer: B
10 What is a function of the placenta? A It acts as a barrier to toxins. B It cushions the fetus from bumps. C It maintains a constant temperature. D It exchanges blood between the fetus and the mother.
1 marks
Answer: A
11 The diagram shows eggs and sperm containing sex chromosomes. 1 2 3 4 egg X X X X Y Y 5 6 7 8 sperm X Y X X X Y Which row gives the correct combination of sex chromosomes for a male and female offspring? male female offspring offspring A 1 and 8 3 and 7 B 2 and 6 2 and 5 C 3 and 8 1 and 7 D 4 and 6 2 and 5
1 marks
Answer: B
10 Which part of the male reproductive system is correctly matched to its function? part function A prostate gland transfers sperm to the urethra B scrotum holds the testes outside of body C testes secrete fluids for sperm to swim in D urethra transfers semen to ovary
1 marks
Answer: B
10 The diagram shows human gamete formation and fertilisation. male gametes male made in V gametes fertilisation occurs in Z female gametes female made in W gametes Which row is correct? structure V structure W structure Z A scrotum uterus oviduct B testes oviduct ovary C testes ovary oviduct D scrotum oviduct uterus
1 marks
Answer: C
10 The body cells of tigers have 38 chromosomes. Which row shows the numbers of chromosomes involved during sexual reproduction in tigers? sperm offspring egg cell zygote cell body cell A 38 38 19 38 B 19 19 38 76 C 19 19 38 38 D 38 38 76 76
1 marks
Answer: C
10 The diagram shows the human male reproductive system. X Y Z Which row identifies structures X, Y and Z? sperm prostate urethra duct gland A X Y Z B X Z Y C Z X Y D Z Y X
1 marks
Answer: D
10 Which statements about human egg and sperm cells are correct? 1 The egg cell’s membrane changes to prevent other sperm from entering it after fertilisation. 2 The egg and sperm cells have a diploid nucleus. 3 The sperm’s enzymes allow it to penetrate the egg to fertilise it. 4 The process of fertilisation occurs in the ovary. A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
1 marks
Answer: A
10 What processes occur in the oviduct? A fertilisation and then the zygote undergoes meiosis B fertilisation and then the zygote undergoes mitosis C zygote undergoes meiosis and then fertilisation occurs D zygote undergoes mitosis and then fertilisation occurs
1 marks
Answer: B
10 The diagram shows the human female reproductive system. Which label shows the oviduct? A B C D
1 marks
Answer: A
8 The diagram shows a sperm cell. Which structure contains enzymes to digest the outer jelly layer of an egg cell? D A C B
1 marks
Answer: A