TopicalSciences - Co-ordinated (Double) 0654ReproductionSexual reproduction in humansPaper 2

Sexual reproduction in humans — Paper 2 · IGCSE Sciences - Co-ordinated (Double) 0654

B15.4· 23 questions · 23 marks · 28 min · 2017–2025· Multiple choice

Every Cambridge IGCSE Sciences - Co-ordinated (Double) Paper 2 question on sexual reproduction in humans, laid out as 6 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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Questions6 pages

Question 1: The diagram shows stages in the development of a fertilised zygote. Which stage becomes implanted in the wall of the uterus? A B C DQuestion 2: The maternal blood leaving the placenta is different in composition from that arriving. What are those differences? carbon oxygen glucose d…Question 3: What is meant by fertilisation? A combining of male and female nuclei B joining of male and female sex organs C movement of sperms through …Question 4: Kangaroos have 16 chromosomes in their skin cells. How many chromosomes are there in a kangaroo sperm cell? A 4 B 8 C 16 D 32Question 5: Which sex chromosomes need to be present in a sperm cell to produce a male zygote? A X only B Y only C XX D XYQuestion 6: During pregnancy, the placenta is used to exchange substances between the mother and the fetus. Which row is correct? substance exchanged d…1 / 6
Question 7: In human reproduction, which cells are haploid?

gametes zygotes

v v

0 Oo WwW >

v x
x v
x xQuestion 8: In human reproduction, which cells are haploid?

gametes zygotes

v v

00 WwW >

v x
x v
x xQuestion 9: In human reproduction, which cells are haploid?

gametes zygotes

v v

00 WwW >

v x
x v
x xQuestion 10: Which row about human gametes is correct?

flagellum energy store shows

gamete present present motility
A female v v Jv
B female Xx v x
Cc…Question 11: Which row is correct for a human sperm cell? flagellum nucleus presence of enzymes A no diploid yes B no haploid no C yes diploid no D yes …2 / 6
Question 12: Which row describes the exchange of substances between a mother and her fetus in mammals? substances moving from substances moving from the…Question 13: Which statements correctly describe the human male gamete? 1 contains enzymes 2 food stores present 3 flagellum present 4 surrounded by a j…Question 14: What is a function of the placenta? A It acts as a barrier to toxins. B It cushions the fetus from bumps. C It maintains a constant tempera…Question 15: The diagram shows eggs and sperm containing sex chromosomes. 1 2 3 4 egg X X X X Y Y 5 6 7 8 sperm X Y X X X Y Which row gives the correct …3 / 6
Question 16: Which part of the male reproductive system is correctly matched to its function? part function A prostate gland transfers sperm to the uret…Question 17: The diagram shows human gamete formation and fertilisation. male gametes male made in V gametes fertilisation occurs in Z female gametes fe…Question 18: The body cells of tigers have 38 chromosomes. Which row shows the numbers of chromosomes involved during sexual reproduction in tigers? spe…4 / 6
Question 19: The diagram shows the human male reproductive system. X Y Z Which row identifies structures X, Y and Z? sperm prostate urethra duct gland A…Question 20: Which statements about human egg and sperm cells are correct? 1 The egg cell’s membrane changes to prevent other sperm from entering it aft…Question 21: What processes occur in the oviduct? A fertilisation and then the zygote undergoes meiosis B fertilisation and then the zygote undergoes mi…5 / 6
Question 22: The diagram shows the human female reproductive system. Which label shows the oviduct? A B C DQuestion 23: The diagram shows a sperm cell. Which structure contains enzymes to digest the outer jelly layer of an egg cell? D A C B6 / 6

Mark scheme23 answers

Answers below. Sit the paper first if you are practising.

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Sciences - Co-ordinated (Double) 0654 · Sexual reproduction in humans — Paper 2

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1C1
2A1
3A1
4B1
5B1
6B1
7B1
8B1
9B1
10B1
11D1
12B1
13B1
14A1
15B1
16B1
17C1
18C1
19D1
20A1
21B1
22A1
23A1
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QuestionAnswerMarksFrom
1C10654/22 May/June 2017
2A10654/21 Oct/Nov 2017
3A10654/23 Oct/Nov 2017
4B10654/21 Oct/Nov 2018
5B10654/22 May/June 2019
6B10654/21 Oct/Nov 2019
7B10654/21 Oct/Nov 2020
8B10654/22 Oct/Nov 2020
9B10654/23 Oct/Nov 2020
10B10654/22 May/June 2021
11D10654/23 May/June 2021
12B10654/22 Oct/Nov 2021
13B10654/22 Feb/March 2022
14A10654/21 Oct/Nov 2022
15B10654/21 May/June 2023
16B10654/21 Oct/Nov 2023
17C10654/22 Oct/Nov 2023
18C10654/22 Feb/March 2024
19D10654/22 May/June 2024
20A10654/23 May/June 2024
21B10654/22 Oct/Nov 2024
22A10654/22 Feb/March 2025
23A10654/23 May/June 2025

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All of Reproduction

Questions as text

Q1 · The diagram shows stages in the development of a fertilised zygote 0654/22 May/June 2017

7 The diagram shows stages in the development of a fertilised zygote. Which stage becomes implanted in the wall of the uterus? A B C D

1 marks

Answer: C

This question in 0654/22 May/June 2017

Q2 · The maternal blood leaving the placenta is different in composition from that arriving 0654/21 Oct/Nov 2017

6 The maternal blood leaving the placenta is different in composition from that arriving. What are those differences? carbon oxygen glucose dioxide A less more less B less more same C more less more D more less same

1 marks

Answer: A

This question in 0654/21 Oct/Nov 2017

Q3 · What is meant by fertilisation? 0654/23 Oct/Nov 2017

6 What is meant by fertilisation? A combining of male and female nuclei B joining of male and female sex organs C movement of sperms through the uterus to an ovum D reproduction

1 marks

Answer: A

This question in 0654/23 Oct/Nov 2017

Q4 · Kangaroos have 16 chromosomes in their skin cells 0654/21 Oct/Nov 2018

10 Kangaroos have 16 chromosomes in their skin cells. How many chromosomes are there in a kangaroo sperm cell? A 4 B 8 C 16 D 32

1 marks

Answer: B

This question in 0654/21 Oct/Nov 2018

Q5 · Which sex chromosomes need to be present in a sperm cell to produce a male zygote? 0654/22 May/June 2019

11 Which sex chromosomes need to be present in a sperm cell to produce a male zygote? A X only B Y only C XX D XY

1 marks

Answer: B

This question in 0654/22 May/June 2019

Q6 · During pregnancy, the placenta is used to exchange substances between the mother and the… 0654/21 Oct/Nov 2019

10 During pregnancy, the placenta is used to exchange substances between the mother and the fetus. Which row is correct? substance exchanged direction A carbon dioxide mother to fetus B glucose mother to fetus C glucose fetus to mother D oxygen fetus to mother

1 marks

Answer: B

This question in 0654/21 Oct/Nov 2019

Q7 · In human reproduction, which cells are haploid? 0654/21 Oct/Nov 2020

10 In human reproduction, which cells are haploid? gametes zygotes v v 0 Oo WwW > v x x v x x

1 marks

Answer: B

This question in 0654/21 Oct/Nov 2020

Q8 · In human reproduction, which cells are haploid? 0654/22 Oct/Nov 2020

10 In human reproduction, which cells are haploid? gametes zygotes v v 00 WwW > v x x v x x

1 marks

Answer: B

This question in 0654/22 Oct/Nov 2020

Q9 · In human reproduction, which cells are haploid? 0654/23 Oct/Nov 2020

10 In human reproduction, which cells are haploid? gametes zygotes v v 00 WwW > v x x v x x

1 marks

Answer: B

This question in 0654/23 Oct/Nov 2020

Q10 · Which row about human gametes is correct? 0654/22 May/June 2021

10 Which row about human gametes is correct? flagellum energy store shows gamete present present motility A female v v Jv B female Xx v x Cc male v v x D male x x v key /=yes X =no

1 marks

Answer: B

This question in 0654/22 May/June 2021

Q11 · Which row is correct for a human sperm cell? 0654/23 May/June 2021

2 Which row is correct for a human sperm cell? flagellum nucleus presence of enzymes A no diploid yes B no haploid no C yes diploid no D yes haploid yes

1 marks

Answer: D

This question in 0654/23 May/June 2021

Q12 · Which row describes the exchange of substances between a mother and her fetus in mammals? 0654/22 Oct/Nov 2021

10 Which row describes the exchange of substances between a mother and her fetus in mammals? substances moving from substances moving from the mother to fetus the fetus to mother A glucose and carbon dioxide urea and oxygen B glucose and oxygen urea and carbon dioxide C urea and carbon dioxide glucose and oxygen D urea and oxygen glucose and carbon dioxide

1 marks

Answer: B

This question in 0654/22 Oct/Nov 2021

Q13 · Which statements correctly describe the human male gamete? 0654/22 Feb/March 2022

10 Which statements correctly describe the human male gamete? 1 contains enzymes 2 food stores present 3 flagellum present 4 surrounded by a jelly coating A 1 and 2 B 1 and 3 C 2 and 3 D 3 and 4

1 marks

Answer: B

This question in 0654/22 Feb/March 2022

Q14 · What is a function of the placenta? 0654/21 Oct/Nov 2022

10 What is a function of the placenta? A It acts as a barrier to toxins. B It cushions the fetus from bumps. C It maintains a constant temperature. D It exchanges blood between the fetus and the mother.

1 marks

Answer: A

This question in 0654/21 Oct/Nov 2022

Q15 · The diagram shows eggs and sperm containing sex chromosomes 0654/21 May/June 2023

11 The diagram shows eggs and sperm containing sex chromosomes. 1 2 3 4 egg X X X X Y Y 5 6 7 8 sperm X Y X X X Y Which row gives the correct combination of sex chromosomes for a male and female offspring? male female offspring offspring A 1 and 8 3 and 7 B 2 and 6 2 and 5 C 3 and 8 1 and 7 D 4 and 6 2 and 5

1 marks

Answer: B

This question in 0654/21 May/June 2023

Q16 · Which part of the male reproductive system is correctly matched to its function? 0654/21 Oct/Nov 2023

10 Which part of the male reproductive system is correctly matched to its function? part function A prostate gland transfers sperm to the urethra B scrotum holds the testes outside of body C testes secrete fluids for sperm to swim in D urethra transfers semen to ovary

1 marks

Answer: B

This question in 0654/21 Oct/Nov 2023

Q17 · The diagram shows human gamete formation and fertilisation 0654/22 Oct/Nov 2023

10 The diagram shows human gamete formation and fertilisation. male gametes male made in V gametes fertilisation occurs in Z female gametes female made in W gametes Which row is correct? structure V structure W structure Z A scrotum uterus oviduct B testes oviduct ovary C testes ovary oviduct D scrotum oviduct uterus

1 marks

Answer: C

This question in 0654/22 Oct/Nov 2023

Q18 · The body cells of tigers have 38 chromosomes 0654/22 Feb/March 2024

10 The body cells of tigers have 38 chromosomes. Which row shows the numbers of chromosomes involved during sexual reproduction in tigers? sperm offspring egg cell zygote cell body cell A 38 38 19 38 B 19 19 38 76 C 19 19 38 38 D 38 38 76 76

1 marks

Answer: C

This question in 0654/22 Feb/March 2024

Q19 · The diagram shows the human male reproductive system 0654/22 May/June 2024

10 The diagram shows the human male reproductive system. X Y Z Which row identifies structures X, Y and Z? sperm prostate urethra duct gland A X Y Z B X Z Y C Z X Y D Z Y X

1 marks

Answer: D

This question in 0654/22 May/June 2024

Q20 · Which statements about human egg and sperm cells are correct? 0654/23 May/June 2024

10 Which statements about human egg and sperm cells are correct? 1 The egg cell’s membrane changes to prevent other sperm from entering it after fertilisation. 2 The egg and sperm cells have a diploid nucleus. 3 The sperm’s enzymes allow it to penetrate the egg to fertilise it. 4 The process of fertilisation occurs in the ovary. A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4

1 marks

Answer: A

This question in 0654/23 May/June 2024

Q21 · What processes occur in the oviduct? 0654/22 Oct/Nov 2024

10 What processes occur in the oviduct? A fertilisation and then the zygote undergoes meiosis B fertilisation and then the zygote undergoes mitosis C zygote undergoes meiosis and then fertilisation occurs D zygote undergoes mitosis and then fertilisation occurs

1 marks

Answer: B

This question in 0654/22 Oct/Nov 2024

Q22 · The diagram shows the human female reproductive system 0654/22 Feb/March 2025

10 The diagram shows the human female reproductive system. Which label shows the oviduct? A B C D

1 marks

Answer: A

This question in 0654/22 Feb/March 2025

Q23 · The diagram shows a sperm cell 0654/23 May/June 2025

8 The diagram shows a sperm cell. Which structure contains enzymes to digest the outer jelly layer of an egg cell? D A C B

1 marks

Answer: A

This question in 0654/23 May/June 2025