TopicalSciences - Co-ordinated (Double) 0654InheritanceChromosomes and genesPaper 2

Chromosomes and genes — Paper 2 · IGCSE Sciences - Co-ordinated (Double) 0654

B16.1· 17 questions · 17 marks · 20 min · 2017–2025· Multiple choice

Every Cambridge IGCSE Sciences - Co-ordinated (Double) Paper 2 question on chromosomes and genes, laid out as 3 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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Questions3 pages

Question 1: What is meant by the term homozygous? A alleles that determine the appearance of an organism B an allele that is effective only when there …Question 2: A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained e…Question 3: A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained e…Question 4: A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained e…Question 5: Which statements about X chromosomes in humans are correct?

present in present in
body cells in body cells of carry genes
males females
A …Question 6: Which statements about X chromosomes in humans are correct?

present in present in
body cells in body cells of carry genes
males females
A …1 / 3
Question 7: Which statements about X chromosomes in humans are correct?

present in present in
body cells in body cells of carry genes
males females
A …Question 8: What contains only the information to produce a specific protein? A chromosome B cytoplasm C gene D nucleusQuestion 9: Which sex chromosomes need to be present in a sperm cell to produce a male zygote? A X only B Y only C XX D XYQuestion 10: Chimpanzee gametes contain one more chromosome than human gametes. What is the chromosome number in a chimpanzee diploid cell? A 23 B 24 C …Question 11: The diagram shows eggs and sperm containing sex chromosomes. 1 2 3 4 egg X X X X Y Y 5 6 7 8 sperm X Y X X X Y Which row gives the correct …2 / 3
Question 12: Which row about the nucleus of human cells is correct? description number of example of nucleus chromosomes of cell A diploid 23 gamete B d…Question 13: Which row shows the sex chromosomes in humans? female male A XX XY B XY XX C YY XX D XX YYQuestion 14: Some information about a donkey and a horse is shown. ● The sperm from a donkey is able to fertilise the egg from a horse. ● The nucleus of…Question 15: Chimpanzee gametes contain one more chromosome than human gametes. What is the chromosome number in a chimpanzee diploid cell? A 23 B 24 C …Question 16: Which combination of chromosomes produces a male in humans? A XO B XY C YY D XXQuestion 17: Sheep have 54 chromosomes in their body cells. Which row is correct for a female sheep? number of chromosomes egg cells in egg cells A 27 h…3 / 3

Mark scheme17 answers

Answers below. Sit the paper first if you are practising.

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Sciences - Co-ordinated (Double) 0654 · Chromosomes and genes — Paper 2

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1C1
2C1
3C1
4C1
5A1
6A1
7A1
8C1
9B1
10D1
11B1
12B1
13A1
14B1
15D1
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QuestionAnswerMarksFrom
1C10654/21 May/June 2017
2C10654/21 May/June 2017
3C10654/22 May/June 2017
4C10654/23 May/June 2017
5A10654/21 Oct/Nov 2017
6A10654/22 Oct/Nov 2017
7A10654/23 Oct/Nov 2017
8C10654/21 Oct/Nov 2018
9B10654/22 May/June 2019
10D10654/21 May/June 2020
11B10654/21 May/June 2023
12B10654/22 May/June 2024
13A10654/23 May/June 2024
14B10654/22 May/June 2025
15D10654/21 Oct/Nov 2025
16B10654/22 Oct/Nov 2025
17A10654/23 Oct/Nov 2025

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Questions as text

Q1 · What is meant by the term homozygous? 0654/21 May/June 2017

9 What is meant by the term homozygous? A alleles that determine the appearance of an organism B an allele that is effective only when there is no dominant allele present C an individual with two alleles of the same gene that are identical D an individual with two different alleles of the same gene

1 marks

Answer: C

This question in 0654/21 May/June 2017

Q2 · A scientist took a single living cheek cell from each of 30 different people 0654/21 May/June 2017

12 A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained each cell so that the sex chromosomes could be observed. How many X chromosomes would the scientist observe? A 15 B 30 C 45 D 60

1 marks

Answer: C

This question in 0654/21 May/June 2017

Q3 · A scientist took a single living cheek cell from each of 30 different people 0654/22 May/June 2017

12 A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained each cell so that the sex chromosomes could be observed. How many X chromosomes would the scientist observe? A 15 B 30 C 45 D 60

1 marks

Answer: C

This question in 0654/22 May/June 2017

Q4 · A scientist took a single living cheek cell from each of 30 different people 0654/23 May/June 2017

12 A scientist took a single living cheek cell from each of 30 different people. 15 of these people were male and 15 were female. He stained each cell so that the sex chromosomes could be observed. How many X chromosomes would the scientist observe? A 15 B 30 C 45 D 60

1 marks

Answer: C

This question in 0654/23 May/June 2017

Q5 · Which statements about X chromosomes in humans are correct? 0654/21 Oct/Nov 2017

4 Which statements about X chromosomes in humans are correct? present in present in body cells in body cells of carry genes males females A v v v B v x v Cc J x x D x v x

1 marks

Answer: A

This question in 0654/21 Oct/Nov 2017

Q6 · Which statements about X chromosomes in humans are correct? 0654/22 Oct/Nov 2017

4 Which statements about X chromosomes in humans are correct? present in present in body cells in body cells of carry genes males females A v v v B v x v Cc J x x D x v x

1 marks

Answer: A

This question in 0654/22 Oct/Nov 2017

Q7 · Which statements about X chromosomes in humans are correct? 0654/23 Oct/Nov 2017

4 Which statements about X chromosomes in humans are correct? present in present in body cells in body cells of carry genes males females A v v v B v x v Cc J x x D x v x

1 marks

Answer: A

This question in 0654/23 Oct/Nov 2017

Q8 · What contains only the information to produce a specific protein? 0654/21 Oct/Nov 2018

11 What contains only the information to produce a specific protein? A chromosome B cytoplasm C gene D nucleus

1 marks

Answer: C

This question in 0654/21 Oct/Nov 2018

Q9 · Which sex chromosomes need to be present in a sperm cell to produce a male zygote? 0654/22 May/June 2019

11 Which sex chromosomes need to be present in a sperm cell to produce a male zygote? A X only B Y only C XX D XY

1 marks

Answer: B

This question in 0654/22 May/June 2019

Q10 · Chimpanzee gametes contain one more chromosome than human gametes 0654/21 May/June 2020

11 Chimpanzee gametes contain one more chromosome than human gametes. What is the chromosome number in a chimpanzee diploid cell? A 23 B 24 C 46 D 48

1 marks

Answer: D

This question in 0654/21 May/June 2020

Q11 · The diagram shows eggs and sperm containing sex chromosomes 0654/21 May/June 2023

11 The diagram shows eggs and sperm containing sex chromosomes. 1 2 3 4 egg X X X X Y Y 5 6 7 8 sperm X Y X X X Y Which row gives the correct combination of sex chromosomes for a male and female offspring? male female offspring offspring A 1 and 8 3 and 7 B 2 and 6 2 and 5 C 3 and 8 1 and 7 D 4 and 6 2 and 5

1 marks

Answer: B

This question in 0654/21 May/June 2023

Q12 · Which row about the nucleus of human cells is correct? 0654/22 May/June 2024

11 Which row about the nucleus of human cells is correct? description number of example of nucleus chromosomes of cell A diploid 23 gamete B diploid 46 body C haploid 23 body D haploid 46 gamete

1 marks

Answer: B

This question in 0654/22 May/June 2024

Q13 · Which row shows the sex chromosomes in humans? 0654/23 May/June 2024

11 Which row shows the sex chromosomes in humans? female male A XX XY B XY XX C YY XX D XX YY

1 marks

Answer: A

This question in 0654/23 May/June 2024

Q14 · Some information about a donkey and a horse is shown 0654/22 May/June 2025

11 Some information about a donkey and a horse is shown. ● The sperm from a donkey is able to fertilise the egg from a horse. ● The nucleus of a body cell from a horse has 64 chromosomes. ● The nucleus of a sperm cell from a donkey has 31 chromosomes. ● The offspring from a cross between a donkey and a horse is called a mule. How many chromosomes are in the nucleus of a body cell from a mule? A 31 B 63 C 64 D 95

1 marks

Answer: B

This question in 0654/22 May/June 2025

Q15 · Chimpanzee gametes contain one more chromosome than human gametes 0654/21 Oct/Nov 2025

12 Chimpanzee gametes contain one more chromosome than human gametes. What is the chromosome number in a chimpanzee diploid cell? A 23 B 24 C 46 D 48

1 marks

Answer: D

This question in 0654/21 Oct/Nov 2025

Q16 · Which combination of chromosomes produces a male in humans? 0654/22 Oct/Nov 2025

12 Which combination of chromosomes produces a male in humans? A XO B XY C YY D XX

1 marks

Answer: B

This question in 0654/22 Oct/Nov 2025

Q17 · Sheep have 54 chromosomes in their body cells 0654/23 Oct/Nov 2025

9 Sheep have 54 chromosomes in their body cells. Which row is correct for a female sheep? number of chromosomes egg cells in egg cells A 27 haploid B 54 haploid C 27 diploid D 54 diploid

1 marks

Answer: A

This question in 0654/23 Oct/Nov 2025