TopicalBiology (9-1) 0970Diseases and immunityDiseases and immunityPaper 1

Diseases and immunity — Paper 1 · IGCSE Biology (9-1) 0970

10.1· 42 questions · 42 marks · 50 min · 2018–2025· Multiple choice

Every Cambridge IGCSE Biology (9-1) Paper 1 question on diseases and immunity, laid out as 11 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

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Questions11 pages

Question 1: Which statement describes a transmissible disease? A a disease caused when a pathogen passes from one host to another B a disease caused wh…Question 2: Antibiotics are used to treat some diseases.

Which diseases could they be effective against?

bacterial
infection SCUIVY
v v
v v
v x
x xQuestion 3: The graph shows the number of people infected with HIV, in one part of the world, between 1985 and 2010. 30 25 number of 20 people infected…1 / 11
Question 4: The human immunodeficiency virus (HIV) can be transmitted in body fluid. Some examples of body fluids are listed. 1 blood 2 saliva 3 semen …Question 5: Some organisms cause transmissible diseases. What is defined as a disease-causing organism? A bacterium B pathogen C phagocyte D virusQuestion 6: Which precautions could help to prevent the spread of AIDS? 1 avoiding the mixing of blood 2 using a femidom 3 using the contraceptive pill…Question 7: The diagram shows a human tooth with an area of decay. area of decay What is likely to have caused the decay? A acids released by bacteria …2 / 11
Question 8: The diagram shows one way the body defends itself against pathogens. bacteria white blood cell What is the name of this defence mechanism? …Question 9: Which type of drug is used to treat bacterial infection? A antibody B antibiotic C depressant D vaccineQuestion 10: The body has several defence mechanisms to protect the body against disease. Which is a chemical barrier? A hair in the nose B mucus C skin…Question 11: What is a chemical barrier to pathogens? A nose hairs B skin C stomach acid D white blood cellsQuestion 12: Which type of infection could be treated successfully with antibiotics?

infection caused by
bacteria resistan t viruses
bacteria
A v v x k…3 / 11
Question 13: What is a chemical barrier to pathogens? A nose hairs B skin C stomach acid D white blood cellsQuestion 14: Which statement about antibiotic use in humans is correct? A Different types of antibiotic are used to remove antibodies from the body. B A…Question 15: Which type of organism causes tooth decay? A arachnid B bacterium C producer D virusQuestion 16: Some functions of blood are listed. 1 antibody production 2 blood clotting 3 oxygen transport 4 phagocytosis What are functions of white bl…Question 17: Which is an example of a transmissible disease? A coronary heart disease due to eating high fat food B cholera after drinking contaminated …Question 18: What is a function of some white blood cells? A to carry glucose B to carry oxygen C to produce antibiotics D to produce antibodies4 / 11
Question 19: The diagram shows the four components of blood separated into layers. Which component is labelled with the correct function? A   plasma – p…Question 20: Some features that help to defend the body against pathogens are listed. 1 mucus 2 skin 3 stomach acid 4 phagocytosis Which features can pr…Question 21: Which substance can be used to treat a bacterial infection? A adrenaline B antibiotics C antigens D insulinQuestion 22: HIV is a sexually transmitted infection (STI). Which methods could be used to reduce the spread of HIV? 1 breast-feed babies 2 education ab…5 / 11
Question 23: The body has several defence mechanisms to protect against disease. Which defence mechanism is a chemical barrier? A hairs in the nose B mu…Question 24: Which disease is caused by a pathogen? A cholera B coronary heart disease C lung cancer D scurvyQuestion 25: Campylobacter is a bacterium that can cause food poisoning. Which word describes Campylobacter? A antibody B disease C pathogen D symptomQuestion 26: What is an example of good personal hygiene in the kitchen? A cooking food at a high temperature B disposing of waste food in sealed contai…Question 27: Which statements about antibiotics are correct? 1 Antibiotics can be used to treat bacterial infections. 2 Antibiotics can be used to treat…6 / 11
Question 28: The table shows which antibiotics are effective against different types of bacteria. The shaded areas show the antibiotic is effective agai…Question 29: Which statement describes a transmissible disease? A a disease caused when a pathogen passes from one host to another B a disease caused wh…Question 30: What is a direct way of transmitting a pathogen? A by contact with contaminated air B by contact with contaminated blood C by contact with …7 / 11
Question 31: The graph shows the number of cases of MRSA in one country between 2001 and 2006. 7500 number of 7000 cases of MRSA 6500 6000 2001 2002 200…Question 32: Which method of pathogen transmission is direct? A breathing in pathogens in air B eating contaminated food C transfusing contaminated bloo…8 / 11
Question 33: The graph shows how the percentage effectiveness of antibiotic F against MRSA bacteria varied between 1980 and 2000. 100 90 80 percentage e…Question 34: What is HIV? A a bacterium B an enzyme C a pathogen D an antibody9 / 11
Question 35: The photomicrograph shows two blood cells. What is the function of these cells? A to carry out phagocytosis B to produce antibodies C to tr…Question 36: Some ways that diseases can be transmitted are listed. 1 airborne droplets 2 blood and needles 3 food and drink 4 unprotected sex Which way…Question 37: Which type of pathogen transmission is by direct contact? A contaminated air B contaminated blood C contaminated food D contaminated surfac…Question 38: Which statement applies to antibiotics? A They kill bacteria. B They kill viruses. C They are produced by platelets. D They are produced by…10 / 11
Question 39: What can reduce the transmission of HIV? A clean water supplies B hygienic food preparations C use of condoms D sewage treatmentQuestion 40: How can the spread of disease be prevented? A leaving food uncovered B only washing hands after meals C using the same equipment to prepare…Question 41: Which term can be used to describe all disease-causing organisms? A bacteria B decomposers C pathogens D virusesQuestion 42: Which statements describe methods of transmission of HIV? 1 eating contaminated food 2 exchange of blood between individuals 3 from a mothe…11 / 11

Mark scheme42 answers

Answers below. Sit the paper first if you are practising.

Pastlit

Biology (9-1) 0970 · Diseases and immunity — Paper 1

IGCSE · topical answer key — answer key (teacher use)

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All of Diseases and immunity

Questions as text

Q1 · Which statement describes a transmissible disease? 0970/11 May/June 2018

19 Which statement describes a transmissible disease? A a disease caused when a pathogen passes from one host to another B a disease caused when a pathogen passes through a host’s body C a disease caused when a pathogen passes to the host’s body only by direct contact D a disease caused when a pathogen passes to the host’s body only by indirect contact

1 marks

Answer: A

This question in 0970/11 May/June 2018

Q2 · Antibiotics are used to treat some diseases 0970/11 May/June 2018

26 Antibiotics are used to treat some diseases. Which diseases could they be effective against? bacterial infection SCUIVY v v v v v x x x

1 marks

Answer: C

This question in 0970/11 May/June 2018

Q3 · The graph shows the number of people infected with HIV, in one part of the world, between… 0970/11 May/June 2018

27 The graph shows the number of people infected with HIV, in one part of the world, between 1985 and 2010. 30 25 number of 20 people infected 15 with HIV / million 10 5 0 1985 1990 1995 2000 2005 2010 Using data from the graph, which statement is correct? A Between 1995 and 2000 the number of people infected with HIV increased by 67%. B Between 1995 and 2000 the number of people infected with HIV increased by 20%. C Between 1990 and 1995 the number of people infected with HIV doubled. D Between 1995 and 2000 the number of people infected with HIV doubled.

1 marks

Answer: A

This question in 0970/11 May/June 2018

Q4 · The human immunodeficiency virus (HIV) can be transmitted in body fluid 0970/11 May/June 2018

30 The human immunodeficiency virus (HIV) can be transmitted in body fluid. Some examples of body fluids are listed. 1 blood 2 saliva 3 semen 4 tear fluid Which body fluids could transmit HIV? A 1, 2, 3 and 4 B 1, 2 and 3 only C 1 and 3 only D 3 only

1 marks

Answer: C

This question in 0970/11 May/June 2018

Q5 · Some organisms cause transmissible diseases 0970/12 Oct/Nov 2018

18 Some organisms cause transmissible diseases. What is defined as a disease-causing organism? A bacterium B pathogen C phagocyte D virus

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2018

Q6 · Which precautions could help to prevent the spread of AIDS? 0970/12 Oct/Nov 2018

27 Which precautions could help to prevent the spread of AIDS? 1 avoiding the mixing of blood 2 using a femidom 3 using the contraceptive pill 4 using a condom A 1 and 3 B 1, 2 and 4 C 2, 3 and 4 D 2 and 4 only

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2018

Q7 · The diagram shows a human tooth with an area of decay 0970/11 May/June 2019

15 The diagram shows a human tooth with an area of decay. area of decay What is likely to have caused the decay? A acids released by bacteria B digestion of the tooth by bacteria C excess of fat in the food D lack of fibre in the food

1 marks

Answer: A

This question in 0970/11 May/June 2019

Q8 · The diagram shows one way the body defends itself against pathogens 0970/11 May/June 2019

20 The diagram shows one way the body defends itself against pathogens. bacteria white blood cell What is the name of this defence mechanism? A antibody production B egestion C phagocytosis D vaccination

1 marks

Answer: C

This question in 0970/11 May/June 2019

Q9 · Which type of drug is used to treat bacterial infection? 0970/11 May/June 2019

28 Which type of drug is used to treat bacterial infection? A antibody B antibiotic C depressant D vaccine

1 marks

Answer: B

This question in 0970/11 May/June 2019

Q10 · The body has several defence mechanisms to protect the body against disease 0970/12 Oct/Nov 2019

18 The body has several defence mechanisms to protect the body against disease. Which is a chemical barrier? A hair in the nose B mucus C skin D white blood cells

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2019

Q11 · What is a chemical barrier to pathogens? 0970/11 May/June 2020

17 What is a chemical barrier to pathogens? A nose hairs B skin C stomach acid D white blood cells

1 marks

Answer: C

This question in 0970/11 May/June 2020

Q12 · Which type of infection could be treated successfully with antibiotics? 0970/11 May/June 2020

26 Which type of infection could be treated successfully with antibiotics? infection caused by bacteria resistan t viruses bacteria A v v x key B Jv x x J/ = yes Cc x v v X =no D x x Jv

1 marks

Answer: B

This question in 0970/11 May/June 2020

Q13 · What is a chemical barrier to pathogens? 0970/12 May/June 2020

17 What is a chemical barrier to pathogens? A nose hairs B skin C stomach acid D white blood cells

1 marks

Answer: C

This question in 0970/12 May/June 2020

Q14 · Which statement about antibiotic use in humans is correct? 0970/12 May/June 2020

26 Which statement about antibiotic use in humans is correct? A Different types of antibiotic are used to remove antibodies from the body. B Antibiotics are injected in childhood to prevent diseases in adults. C Antibiotics are used to treat diseases caused by viruses. D Different types of antibiotic are used because bacteria can become resistant.

1 marks

Answer: D

This question in 0970/12 May/June 2020

Q15 · Which type of organism causes tooth decay? 0970/12 Oct/Nov 2020

16 Which type of organism causes tooth decay? A arachnid B bacterium C producer D virus

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2020

Q16 · Some functions of blood are listed 0970/12 Oct/Nov 2020

20 Some functions of blood are listed. 1 antibody production 2 blood clotting 3 oxygen transport 4 phagocytosis What are functions of white blood cells? A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2020

Q17 · Which is an example of a transmissible disease? 0970/12 Oct/Nov 2020

21 Which is an example of a transmissible disease? A coronary heart disease due to eating high fat food B cholera after drinking contaminated water C liver damage due to drinking alcohol D lung cancer due to inhaling tobacco smoke

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2020

Q18 · What is a function of some white blood cells? 0970/11 May/June 2021

21 What is a function of some white blood cells? A to carry glucose B to carry oxygen C to produce antibiotics D to produce antibodies

1 marks

Answer: D

This question in 0970/11 May/June 2021

Q19 · The diagram shows the four components of blood separated into layers 0970/12 Oct/Nov 2021

20 The diagram shows the four components of blood separated into layers. Which component is labelled with the correct function? A plasma – production of antibodies B platelets – blood clotting D white blood cells – C red blood cells – transport of oxygen phagocytosis

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2021

Q20 · Some features that help to defend the body against pathogens are listed 0970/12 Oct/Nov 2021

21 Some features that help to defend the body against pathogens are listed. 1 mucus 2 skin 3 stomach acid 4 phagocytosis Which features can prevent pathogens entering body tissues? A 1, 2, 3 and 4 B 1, 2 and 3 only C 2 and 3 only D 4 only

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2021

Q21 · Which substance can be used to treat a bacterial infection? 0970/12 Oct/Nov 2021

29 Which substance can be used to treat a bacterial infection? A adrenaline B antibiotics C antigens D insulin

1 marks

Answer: B

This question in 0970/12 Oct/Nov 2021

Q22 · HIV is a sexually transmitted infection (STI) 0970/12 Oct/Nov 2021

32 HIV is a sexually transmitted infection (STI). Which methods could be used to reduce the spread of HIV? 1 breast-feed babies 2 education about how HIV is spread 3 provide easy access to condoms 4 provide needle exchange schemes for drug users A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4

1 marks

Answer: D

This question in 0970/12 Oct/Nov 2021

Q23 · The body has several defence mechanisms to protect against disease 0970/11 May/June 2022

21 The body has several defence mechanisms to protect against disease. Which defence mechanism is a chemical barrier? A hairs in the nose B mucus C skin D white blood cells

1 marks

Answer: B

This question in 0970/11 May/June 2022

Q24 · Which disease is caused by a pathogen? 0970/12 May/June 2022

21 Which disease is caused by a pathogen? A cholera B coronary heart disease C lung cancer D scurvy

1 marks

Answer: A

This question in 0970/12 May/June 2022

Q25 · Campylobacter is a bacterium that can cause food poisoning 0970/12 Oct/Nov 2022

21 Campylobacter is a bacterium that can cause food poisoning. Which word describes Campylobacter? A antibody B disease C pathogen D symptom

1 marks

Answer: C

This question in 0970/12 Oct/Nov 2022

Q26 · What is an example of good personal hygiene in the kitchen? 0970/11 May/June 2023

21 What is an example of good personal hygiene in the kitchen? A cooking food at a high temperature B disposing of waste food in sealed containers C storing uncooked meat in a fridge D washing hands before eating food

1 marks

Answer: D

This question in 0970/11 May/June 2023

Q27 · Which statements about antibiotics are correct? 0970/11 May/June 2023

30 Which statements about antibiotics are correct? 1 Antibiotics can be used to treat bacterial infections. 2 Antibiotics can be used to treat viral infections. 3 Antibiotics are not effective against resistant bacteria. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

1 marks

Answer: C

This question in 0970/11 May/June 2023

Q28 · The table shows which antibiotics are effective against different types of bacteria 0970/12 May/June 2023

29 The table shows which antibiotics are effective against different types of bacteria. The shaded areas show the antibiotic is effective against that type of bacteria. type of bacteria antibiotic MRSA Streptococcus Pseudomonas Anaerobes 1 2 3 4 5 6 A person has a disease caused by a type of Streptococcus bacteria and a second infection caused by a type of Pseudomonas bacteria. Which antibiotic should be taken? A 1 or 6 B 2 or 4 C 3 or 4 D 5 or 6

1 marks

Answer: B

This question in 0970/12 May/June 2023

Q29 · Which statement describes a transmissible disease? 0970/12 Oct/Nov 2023

20 Which statement describes a transmissible disease? A a disease caused when a pathogen passes from one host to another B a disease caused when a pathogen passes through a host’s body C a disease caused when a pathogen passes to the host’s body only by direct contact D a disease caused when a pathogen passes to the host’s body only by indirect contact

1 marks

Answer: A

This question in 0970/12 Oct/Nov 2023

Q30 · What is a direct way of transmitting a pathogen? 0970/11 May/June 2024

24 What is a direct way of transmitting a pathogen? A by contact with contaminated air B by contact with contaminated blood C by contact with contaminated food D by contact with contaminated surfaces

1 marks

Answer: B

This question in 0970/11 May/June 2024

Q31 · The graph shows the number of cases of MRSA in one country between 2001 and 2006 0970/11 May/June 2024

30 The graph shows the number of cases of MRSA in one country between 2001 and 2006. 7500 number of 7000 cases of MRSA 6500 6000 2001 2002 2003 2004 2005 2006 year Between which years was the greatest change in the number of cases of MRSA? A 2002 and 2003 B 2003 and 2004 C 2004 and 2005 D 2005 and 2006

1 marks

Answer: D

This question in 0970/11 May/June 2024

Q32 · Which method of pathogen transmission is direct? 0970/12 May/June 2024

22 Which method of pathogen transmission is direct? A breathing in pathogens in air B eating contaminated food C transfusing contaminated blood D touching a door handle that has pathogens on it

1 marks

Answer: C

This question in 0970/12 May/June 2024

Q33 · The graph shows how the percentage effectiveness of antibiotic F against MRSA bacteria… 0970/12 May/June 2024

28 The graph shows how the percentage effectiveness of antibiotic F against MRSA bacteria varied between 1980 and 2000. 100 90 80 percentage effectiveness of antibiotic F 70 against MRSA 60 50 40 1980 1990 2000 time / year What is a correct conclusion from the graph? A Antibiotic F was completely ineffective against MRSA in 2000. B Antibiotic F was most effective in 1982. C MRSA developed resistance to antibiotic F between 1981 and 2000. D The greatest decrease in effectiveness of antibiotic F against MRSA was between 1988 and 1990.

1 marks

Answer: C

This question in 0970/12 May/June 2024

Question 34 0970/12 May/June 2024

32 What is HIV? A a bacterium B an enzyme C a pathogen D an antibody

1 marks

Answer: C

This question in 0970/12 May/June 2024

Q35 · The photomicrograph shows two blood cells 0970/12 Oct/Nov 2024

24 The photomicrograph shows two blood cells. What is the function of these cells? A to carry out phagocytosis B to produce antibodies C to transport oxygen D to transport vitamins

1 marks

Answer: C

This question in 0970/12 Oct/Nov 2024

Q36 · Some ways that diseases can be transmitted are listed 0970/12 Oct/Nov 2024

35 Some ways that diseases can be transmitted are listed. 1 airborne droplets 2 blood and needles 3 food and drink 4 unprotected sex Which ways can transmit HIV? A 1 and 3 B 1 only C 2 and 4 D 4 only

1 marks

Answer: C

This question in 0970/12 Oct/Nov 2024

Q37 · Which type of pathogen transmission is by direct contact? 0970/11 May/June 2025

24 Which type of pathogen transmission is by direct contact? A contaminated air B contaminated blood C contaminated food D contaminated surfaces

1 marks

Answer: B

This question in 0970/11 May/June 2025

Q38 · Which statement applies to antibiotics? 0970/11 May/June 2025

28 Which statement applies to antibiotics? A They kill bacteria. B They kill viruses. C They are produced by platelets. D They are produced by white blood cells.

1 marks

Answer: A

This question in 0970/11 May/June 2025

Q39 · What can reduce the transmission of HIV? 0970/11 May/June 2025

31 What can reduce the transmission of HIV? A clean water supplies B hygienic food preparations C use of condoms D sewage treatment

1 marks

Answer: C

This question in 0970/11 May/June 2025

Q40 · How can the spread of disease be prevented? 0970/12 May/June 2025

19 How can the spread of disease be prevented? A leaving food uncovered B only washing hands after meals C using the same equipment to prepare raw and cooked food D washing hands before and after handling raw food

1 marks

Answer: D

This question in 0970/12 May/June 2025

Q41 · Which term can be used to describe all disease-causing organisms? 0970/12 Oct/Nov 2025

15 Which term can be used to describe all disease-causing organisms? A bacteria B decomposers C pathogens D viruses

1 marks

Answer: C

This question in 0970/12 Oct/Nov 2025

Q42 · Which statements describe methods of transmission of HIV? 0970/12 Oct/Nov 2025

27 Which statements describe methods of transmission of HIV? 1 eating contaminated food 2 exchange of blood between individuals 3 from a mother to a fetus in pregnancy 4 insect bites 5 unprotected sex A 1, 2 and 5 B 1, 3 and 4 C 2, 3 and 5 D 5 only

1 marks

Answer: C

This question in 0970/12 Oct/Nov 2025