TopicalScience - Combined 0653Diseases and immunityDiseases and immunityPaper 2

Diseases and immunity — Paper 2 · IGCSE Science - Combined 0653

B10.1· 11 questions · 11 marks · 13 min · 2017–2025· Multiple choice

Every Cambridge IGCSE Science - Combined Paper 2 question on diseases and immunity, laid out as 3 A4 pages with the mark scheme below. Nothing is left out. Free to read, no account.

Different topic or paper

Questions3 pages

Question 1: How does HIV affect the immune system? A It decreases the number of platelets. B It destroys red blood cells. C It increases the number of …Question 2: Which type of blood cell is affected by the human immuno-deficiency virus (HIV) and what effect does the virus have on those cells? type of…Question 3: What effect does HIV have on the components of blood? A Blood does not clot as quickly. B Plasma can no longer carry hormones. C Red blood …Question 4: What are possible causes of coronary heart disease?

exercise smoking stress
A Jv Jv x
B Jv x Jv
Cc x x x
D x Jv JvQuestion 5: A sample of blood is taken from a person who often gets infections. The blood is also slow to clot. Which blood components are likely to be…1 / 3
Question 6: Which type of blood cell is affected by the human immunodeficiency virus (HIV) and which effect does the virus have on those cells? type of…Question 7: Which row shows how active immunity is gained?

from antibodies
supplied in
an injection

by vaccination

after an
infection by
a pathogen
…Question 8: What is a function of hydrochloric acid in the stomach? A to help absorption of all food in the stomach B to kill microorganisms in the ing…Question 9: Which row describes viruses?

are have a
pathogens protein coat

contain
genetic material

v

v
x
x

v

x
v
x

Qe Ow® OSQuestion 10: Which statement about the use of antibiotics is correct? A Overuse of antibiotics causes the development of bacteria such as MRSA. B Antibi…2 / 3
Question 11: The diagrams show features of plant cells and viruses that are different and features that are common to both. Which diagram is correct? A …3 / 3

Mark scheme11 answers

Answers below. Sit the paper first if you are practising.

Pastlit

Science - Combined 0653 · Diseases and immunity — Paper 2

IGCSE · topical answer key — answer key (teacher use)

Question

Answer

Marks

1D1
2D1
3D1
4D1
5C1
6D1
7C1
8B1
9A1
10A1
11D1
1 / 1
QuestionAnswerMarksFrom
1D10653/22 Feb/March 2017
2D10653/22 May/June 2017
3D10653/23 May/June 2017
4D10653/22 Feb/March 2018
5C10653/22 May/June 2023
6D10653/23 May/June 2024
7C10653/21 May/June 2025
8B10653/22 May/June 2025
9A10653/22 May/June 2025
10A10653/22 May/June 2025
11D10653/22 Oct/Nov 2025

Another paper, or another topic

All of Diseases and immunity

Questions as text

Q1 · How does HIV affect the immune system? 0653/22 Feb/March 2017

11 How does HIV affect the immune system? A It decreases the number of platelets. B It destroys red blood cells. C It increases the number of white blood cells. D It reduces antibody formation.

1 marks

Answer: D

This question in 0653/22 Feb/March 2017

Q2 · Which type of blood cell is affected by the human immuno-deficiency virus (HIV) and what… 0653/22 May/June 2017

11 Which type of blood cell is affected by the human immuno-deficiency virus (HIV) and what effect does the virus have on those cells? type of blood cell effect on the blood cell A red prevents them carrying oxygen B red stops them from making the blood clot C white stops them from performing phagocytosis D white reduces antibody production

1 marks

Answer: D

This question in 0653/22 May/June 2017

Q3 · What effect does HIV have on the components of blood? 0653/23 May/June 2017

11 What effect does HIV have on the components of blood? A Blood does not clot as quickly. B Plasma can no longer carry hormones. C Red blood cells carry less oxygen. D White blood cells make fewer antibodies.

1 marks

Answer: D

This question in 0653/23 May/June 2017

Q4 · What are possible causes of coronary heart disease? 0653/22 Feb/March 2018

8 What are possible causes of coronary heart disease? exercise smoking stress A Jv Jv x B Jv x Jv Cc x x x D x Jv Jv

1 marks

Answer: D

This question in 0653/22 Feb/March 2018

Q5 · A sample of blood is taken from a person who often gets infections 0653/22 May/June 2023

8 A sample of blood is taken from a person who often gets infections. The blood is also slow to clot. Which blood components are likely to be at a lower level than normal? 1 platelets 2 red blood cells 3 white blood cells A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

1 marks

Answer: C

This question in 0653/22 May/June 2023

Q6 · Which type of blood cell is affected by the human immunodeficiency virus (HIV) and which… 0653/23 May/June 2024

12 Which type of blood cell is affected by the human immunodeficiency virus (HIV) and which effect does the virus have on those cells? type of blood cell effect on the blood cell A red prevents them carrying oxygen B red reduces antibody production C white prevents them carrying oxygen D white reduces antibody production

1 marks

Answer: D

This question in 0653/23 May/June 2024

Q7 · Which row shows how active immunity is gained? 0653/21 May/June 2025

12 Which row shows how active immunity is gained? from antibodies supplied in an injection by vaccination after an infection by a pathogen \ \ & & key /=yes X =no

1 marks

Answer: C

This question in 0653/21 May/June 2025

Q8 · What is a function of hydrochloric acid in the stomach? 0653/22 May/June 2025

8 What is a function of hydrochloric acid in the stomach? A to help absorption of all food in the stomach B to kill microorganisms in the ingested food C to prevent chemical digestion D to prevent the stomach contents being too acidic

1 marks

Answer: B

This question in 0653/22 May/June 2025

Q9 · Which row describes viruses? 0653/22 May/June 2025

10 Which row describes viruses? are have a pathogens protein coat contain genetic material v v x x v x v x Qe Ow® OS

1 marks

Answer: A

This question in 0653/22 May/June 2025

Q10 · Which statement about the use of antibiotics is correct? 0653/22 May/June 2025

12 Which statement about the use of antibiotics is correct? A Overuse of antibiotics causes the development of bacteria such as MRSA. B Antibiotics are prescribed for infections caused by viruses and bacteria. C Antibiotics increase reproduction of non-resistant bacteria. D Antibiotics only kill resistant bacteria.

1 marks

Answer: A

This question in 0653/22 May/June 2025

Q11 · The diagrams show features of plant cells and viruses that are different and features… 0653/22 Oct/Nov 2025

11 The diagrams show features of plant cells and viruses that are different and features that are common to both. Which diagram is correct? A B plant cell virus plant cell virus genetic ribosomes genetic material cell wall cell wall ribosomes material protein protein coat coat C D plant cell virus plant cell virus genetic ribosomes material protein genetic protein ribosomes coat material coat cell wall cell wall

1 marks

Answer: D

This question in 0653/22 Oct/Nov 2025