Cambridge A Level Biology 9700 — 2015 Oct/Nov Paper 1 · Variant 3
9700/13/O/N/15 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper16 pages
















Mark scheme2 pages
Answers below. Sit the paper first if you are practising.


Questions as text
Q1 · Which size of ribosome is found in chloroplasts?
1 Which size of ribosome is found in chloroplasts? A 60S B 70S C 80S D 90S
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q2 · Different units are used when measuring biological specimens
2 Different units are used when measuring biological specimens. In which rows are the same measurements correctly expressed in each of the units shown in the column headings? mm µm nm 1 1.0 1.0 × 103 1.0 × 106 2 2.5 2.5 × 103 2.5 × 106 3 5.0 5.0 × 104 5.0 × 107 4 25.0 2.5 × 104 2.5 × 107 A 1, 2, 3 and 4 B 1, 2 and 4 only C 1 and 2 only D 3 and 4 only
Mark scheme: B
Q3 · Which features of cilia and root hairs are correct?
3 Which features of cilia and root hairs are correct? cannot be more than one increase cell resolved with contain present on a surface area the light vacuoles cell microscope A cilia cilia root hairs root hairs B cilia root hairs cilia cilia C root hairs cilia root hairs cilia D root hairs root hairs cilia root hairs
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q4 · The diagram shows a typical animal cell
4 The diagram shows a typical animal cell. Each labelled structure is involved with the synthesis of biological molecules. 1 2 3 4 Within which structures are glycoproteins, proteins and steroids synthesised? glycoproteins proteins steroids A 2 3 1 B 2 3 4 C 4 2 3 D 4 1 2
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q5 · What is present in a Vibrio cholerae cell?
5 What is present in a Vibrio cholerae cell? cell Golgi wall body A B C D rough endoplasmic reticulum
Mark scheme: A
More questions on Cells as the basic units of living organisms
Q6 · What is correct for a typical prokaryotic cell?
6 What is correct for a typical prokaryotic cell? cell wall cell diameter ribosomes A cellulose 1-5 µm 70S B cellulose 5-40 µm 70S and 80S C peptidoglycan 1-5 µm 70S D peptidoglycan 5-40 µm 70S and 80S
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q7 · The table shows the results of tests carried out on a sample of biological molecules
7 The table shows the results of tests carried out on a sample of biological molecules. test colour observed Benedict’s blue biuret purple iodine blue-black Which shows the types of molecules present in the sample? protein sugar starch A v x x B x v x Cc v x v D x v v key J present X absent
Mark scheme: C
Q8 · The synthesis of biological molecules requires the formation of bonds
8 The synthesis of biological molecules requires the formation of bonds. Which row is correct? a bond forms between a β-1,4 bond forms the hydroxyl group of the carboxylic the phosphate of one between the monomers acid group is removed and a monomer and the sugar to give an unbranched carbon-nitrogen bond is formed to of the next monomer chain give an unbranched chain A polynucleotide amylose polypeptide B polynucleotide cellulose polypeptide C phospholipid amylose polynucleotide D phospholipid cellulose polynucleotide
Mark scheme: B
Q9 · Which row describes a triglyceride?
9 Which row describes a triglyceride? hydrophobic insoue in A v v key B v x ¥ correct Cc x v X not correct D x x
Mark scheme: B
Q10 · High concentrations of urea break all bonds, except covalent bonds, in protein molecules
10 High concentrations of urea break all bonds, except covalent bonds, in protein molecules. Which level of protein structure would remain unchanged when a protein is treated with urea? A primary B secondary C tertiary D quaternary
Mark scheme: A
Q11 · Haemoglobin, a globular protein, consists of four polypeptide chains, two alpha chains…
11 Haemoglobin, a globular protein, consists of four polypeptide chains, two alpha chains and two beta chains. In normal individuals, in the DNA which codes for each beta chain, the sixth triplet has a code for glutamic acid. In individuals with sickle cell anaemia this base triplet mutates and codes for valine. What does this mutation change in the haemoglobin molecule? A the iron content B the primary structure C the quaternary structure D the secondary structure
Mark scheme: B
Q12 · The graph shows the concentration of one of the substances which is involved in an…
12 The graph shows the concentration of one of the substances which is involved in an enzyme-catalysed reaction. concentration X time Which substance is shown by line X? A enzyme B enzyme-product complex C enzyme-substrate complex D substrate
Mark scheme: A
Q13 · What describes the induced fit mode of action of an enzyme?
13 What describes the induced fit mode of action of an enzyme? A The binding of the active site to the substrate causes the enzyme to change shape. B The substrate and active site have complementary shapes that form temporary bonds. C The substrate causes a change in enzyme shape so the active site can bind. D The substrate changes shape so it can bind to the active site.
Mark scheme: C
Q14 · Line X represents the course of an enzyme-catalysed reaction under optimum conditions
14 Line X represents the course of an enzyme-catalysed reaction under optimum conditions. Line Y shows the action of the same enzyme on the same substrate but with one variable changed: substrate concentration or pH or temperature. 100 percentage Y of unreacted 50 substrate molecules X 0 time Which changes to the variables could give the results shown by line Y? 1 decreased substrate concentration 2 higher pH 3 lower temperature A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: D
Q15 · Which descriptions are correct about transport across cell surface membranes?
15 Which descriptions are correct about transport across cell surface membranes? active processes passive processes A active transport exocytosis and osmosis B active transport and exocytosis endocytosis and diffusion C endocytosis and exocytosis diffusion and osmosis D exocytosis and active transport osmosis and endocytosis
Mark scheme: C
Q16 · Which statements about the fluid mosaic model of a membrane are correct?
16 Which statements about the fluid mosaic model of a membrane are correct? 1 Saturated fatty acid tails inhibit the movement of phospholipids in the membrane. 2 Glycoproteins in the outer layer of the membrane can move. 3 Channel proteins are fixed in position. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: B
Q17 · The diagram shows apparatus set up to investigate diffusion
17 The diagram shows apparatus set up to investigate diffusion. selectively 20% glucose permeable solution membrane Y 10% glucose solution in V What shows net diffusion of glucose and water molecules? A glucose and water into V B glucose and water into Y C glucose into V and water into Y D glucose into Y and water into V
Mark scheme: C
Q18 · The photomicrograph shows a cell undergoing mitosis
18 The photomicrograph shows a cell undergoing mitosis. What is happening in this cell? A Centrioles are replicating. B Chromatin is condensing. C DNA is replicating. D Spindle microtubules are shortening.
Mark scheme: D
Q19 · Which row shows the products of mitosis, reduction division (meiosis) and fertilisation?
19 Which row shows the products of mitosis, reduction division (meiosis) and fertilisation? products products of product of of mitosis meiosis fertilisation A four diploid cells two diploid cells diploid cell B four haploid cells four diploid cells haploid cell C two diploid cells four haploid cells diploid cell D two diploid cells two haploid cells haploid cell
Mark scheme: C
More questions on Replication and division of nuclei and cells
Q20 · Which statements describe how a gene mutation can lead to the production of a…
20 Which statements describe how a gene mutation can lead to the production of a non-functional protein? 1 During transcription an incorrect nucleotide is added to a DNA molecule. 2 A codon in the mRNA transcribed from the mutated gene is changed. 3 The order of the bases in an anticodon on tRNA is altered during translation. A 1, 2 and 3 B 1 and 2 only C 2 and 3 only D 2 only
Mark scheme: D
Q21 · Some antibiotics kill prokaryotes by binding to RNA polymerase
21 Some antibiotics kill prokaryotes by binding to RNA polymerase. What effect will this have on protein synthesis? A Codons on mRNA will be unable to hydrogen bond to complementary anticodons on tRNA. B Condensation reactions joining RNA nucleotides will not take place to form mRNA. C DNA will not unwind and unzip to allow for base-pairing with RNA nucleotides. D Free RNA nucleotides will not base-pair to exposed bases on the DNA template strand.
Mark scheme: B
Q22 · Which row correctly describes cytosine?
22 Which row correctly describes cytosine? number of hydrogen bonds ring structure it forms with its type of base complementary base A double three purine B double two pyrimidine C single three pyrimidine D single two purine
Mark scheme: C
More questions on Structure of nucleic acids and replication of DNA
Q23 · The photomicrograph shows a transverse section of a leaf
23 The photomicrograph shows a transverse section of a leaf. Which cell has the least negative water potential? C B D A
Mark scheme: A
Q24 · The diagram shows the results of an experiment on transpiration using two different leaves
24 The diagram shows the results of an experiment on transpiration using two different leaves. Each leaf was left on a balance in daylight in a closed room and their mass recorded at 1 hour intervals. mass of leaf leaf 1 leaf 2 0 1 2 3 4 5 time / hours Which conclusions could be correct? 1 The loss in mass is mainly due to evaporation of water. 2 The stomata in both leaves close after 1 hour. 3 Leaf 1 has a larger surface area than leaf 2. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: B
Q25 · Which processes are involved in the transport of sucrose in plants?
25 Which processes are involved in the transport of sucrose in plants? 1 active transport 2 mass flow 3 osmosis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: A
Q26 · Which changes to the water potential and the volume of liquid in the phloem occur when…
26 Which changes to the water potential and the volume of liquid in the phloem occur when carbohydrate is moved from phloem sieve tubes into a sink? water potential in volume of liquid phloem sieve in phloem tubes becomes sieve tubes A less negative decreased B less negative increased C more negative decreased D more negative increased
Mark scheme: A
Q27 · Which reactions take place in a capillary in an active tissue?
27 Which reactions take place in a capillary in an active tissue? 1 the formation of carbonic acid from carbon dioxide and water 2 the formation of carbaminohaemoglobin from carbon dioxide and haemoglobin 3 the formation of haemoglobinic acid from haemoglobin and hydrogen ions 4 the formation of carbon dioxide and water from hydrogen carbonate ions and hydrogen ions A 1, 2, 3 and 4 B 1, 2 and 3 only C 2 and 4 only D 3 and 4 only
Mark scheme: B
Q28 · What is present in the blood in human veins?
28 What is present in the blood in human veins? 1 collagen 2 carbonic anhydrase 3 oxyhaemoglobin A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: D
Q29 · The diagram shows the electrical activity in cardiac muscle during one heart beat
29 The diagram shows the electrical activity in cardiac muscle during one heart beat. R electrical activity T P O Q S time What is happening at each of the labelled stages in the cardiac cycle? O P QRS T A atria contract atrio-ventricular atria relax ventricles contract valve opens B impulse leaves AVN ventricles contract atria relax atrio-ventricular valve closes C impulse leaves SAN atria contract ventricles contract ventricles relax D ventricles relax atria contract atrio-ventricular ventricles relax valve closes
Mark scheme: C
Q30 · Which statement about the pulmonary artery is correct?
30 Which statement about the pulmonary artery is correct? A it contains a series of valves B it contains blood at high pressure C it contains blood moving towards the heart D it contains oxygenated blood
Mark scheme: B
Q31 · Red blood cells may contain a molecule known as 2,3-bisphophoglycerate (2,3BPG)
31 Red blood cells may contain a molecule known as 2,3-bisphophoglycerate (2,3BPG). When 2,3BPG binds to haemoglobin a higher partial pressure of oxygen is needed to bring about 50% saturation of haemoglobin with oxygen. Which statement about the effect of 2,3BPG is correct? A 2,3BPG in red blood cells causes the oxygen dissociation curve to shift to the left. B Binding of 2,3BPG to haemoglobin reduces the Bohr effect. C The binding of 2,3BPG to haemoglobin lowers the affinity of the haemoglobin for oxygen. D When 2,3BPG is absent, oxyhaemoglobin is less likely to unload oxygen.
Mark scheme: C
Q32 · What is a correct location of cartilage and smooth muscle in the human gas exchange…
32 What is a correct location of cartilage and smooth muscle in the human gas exchange system? cartilage smooth muscle A bronchioles bronchioles B bronchioles trachea C trachea alveoli D trachea bronchi
Mark scheme: D
Q33 · Which factors maintain the diffusion gradient for carbon dioxide at the surface of the…
33 Which factors maintain the diffusion gradient for carbon dioxide at the surface of the alveoli? 1 blood flow past the alveoli 2 breathing movement exchanging air in the lungs 3 thin epithelial lining of the alveoli A 1 and 2 B 1 and 3 C 2 and 3 D 1 only
Mark scheme: A
Q34 · The surface tension of the layer of liquid lining the alveoli tends to pull the walls…
34 The surface tension of the layer of liquid lining the alveoli tends to pull the walls inwards so alveoli could collapse. Which statements could explain how this is prevented? 1 alveolar fluid is moved around by cilia 2 elastic fibres keep the alveoli open 3 epithelial cells secrete a chemical that reduces the cohesion in water A 1 and 2 B 1 and 3 C 2 and 3 D 3 only
Mark scheme: D
Q35 · The data shows how the number of human deaths caused by the bacterium Staphylococcus…
35 The data shows how the number of human deaths caused by the bacterium Staphylococcus aureus has changed over a period of five years. Methicillin is an antibiotic used to treat a disease caused by S. aureus. MRSA is methicillin-resistant S. aureus. total number of deaths total number of deaths year caused by S. aureus caused by MRSA 1 369 355 2 452 431 3 456 681 4 420 890 5 428 1512 Which statement is not supported by this data? A More people have MRSA so the disease spreads. B MRSA is more likely to lead to death than S. aureus. C Resistant strains of MRSA are becoming more common. D S. aureus will always cause humans to die.
Mark scheme: D
Q36 · What describes natural active immunity?
36 What describes natural active immunity? A protection against a pathogen by an injection of antibodies B protection against a pathogen by drinking colostrum containing antibodies C stimulation of lymphocytes by antigens contained in a vaccine D stimulation of lymphocytes by antigens on the surface of invading pathogens
Mark scheme: D
Q37 · The bacterium that causes the disease tetanus produces a toxin that acts as an antigen
37 The bacterium that causes the disease tetanus produces a toxin that acts as an antigen. The graph shows the concentration of an antibody in the blood of two people, G and H. On day 0, G was injected with antibodies to the tetanus toxin and H was injected with the vaccine for tetanus. 25 G H 20 antibody 15 concentration / arbitrary units 10 5 0 0 5 10 15 20 time / days time of injection time of infection with tetanus bacteria What would be the result after G and H were infected with the tetanus bacteria on day 20? A concentration of antibodies in H would remain constant B G would fail to produce tetanus antibodies C G would peak in antibody production 12 days after infection D H would produce a new antibody peak 12 days after infection
Mark scheme: C
Q38 · What name is given to all the organisms of the same species living in an area?
38 What name is given to all the organisms of the same species living in an area? A community B ecosystem C niche D population
Mark scheme: D
Q39 · The table shows the results of a field study of four species in a food chain in an area…
39 The table shows the results of a field study of four species in a food chain in an area of woodland. number of biomass of one individual energy value per unit species individuals / arbitrary units mass / arbitrary units R 10 000 0.1 1.0 S 5 10.0 2.0 T 500 0.002 1.8 U 3 300 000.0 0.5 What is the energy flow in the food chain? from to A R T S U B S T R U C U R S T D U S T R
Mark scheme: C
Q40 · The diagram shows a simplified nitrogen cycle
40 The diagram shows a simplified nitrogen cycle. Which arrow represents the activity of nitrogen-fixing bacteria? nitrogen in atmosphere A plant animal proteins proteins D death and decay B ammonium compounds nitrites C nitrates
Mark scheme: A
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
5Transport mechanisms4Biodiversity3The gas exchange system3Antibiotics2Carbohydrates and lipids2Mode of action of enzymes2Movement into and out of cells2Proteins2The circulatory system2Transport of oxygen and carbon dioxide2Antibodies and vaccination1Chromosome behaviour in mitosis1Factors that affect enzyme action1Fluid mosaic membranes1Protein synthesis1Replication and division of nuclei and cells1Structure of nucleic acids and replication of DNA1Testing for biological molecules1The heart1The immune system1The microscope in cell studies1What you needed in this session
Cambridge’s own grade thresholds for 2015 Oct/Nov, Paper 1 · Variant 3. A higher threshold means an easier paper — the bar moves with how the cohort did.