Cambridge A Level Biology 9700 — 2015 Oct/Nov Paper 1 · Variant 2
9700/12/O/N/15 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper16 pages
















Mark scheme2 pages
Answers below. Sit the paper first if you are practising.


Questions as text
Q1 · Which size of ribosome is found in mitochondria?
1 Which size of ribosome is found in mitochondria? A 60S B 70S C 80S D 90S
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q2 · Different units are used when measuring biological specimens
2 Different units are used when measuring biological specimens. Which measurement in mm has not been correctly converted into both µm and nm? mm µm nm A 1.0 1.0 × 103 1.0 × 106 B 2.5 2.5 × 103 2.5 × 106 C 5.0 5.0 × 104 5.0 × 107 D 25.0 2.5 × 104 2.5 × 107
Mark scheme: C
Q3 · Which features of microvilli and root hairs are correct?
3 Which features of microvilli and root hairs are correct? cannot be more than one increase cell resolved with contain present on a surface area the light vacuoles cell microscope A microvilli microvilli root hairs root hairs B microvilli root hairs microvilli microvilli C root hairs microvilli root hairs microvilli D root hairs root hairs microvilli root hairs
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q4 · Lysosomes have a variety of different shapes and sizes, making them difficult to identify
4 Lysosomes have a variety of different shapes and sizes, making them difficult to identify. What describes a lysosome? A a vesicle containing enzymes, enclosed by a double membrane, that is budded off the endoplasmic reticulum B a vesicle containing hydrolytic enzymes and surrounded by a single membrane, found only in phagocytes C a vesicle enclosed by a single membrane, containing several different hydrolytic enzymes that may act inside or outside the cell D a vesicle surrounded by a double membrane, containing enzymes which can hydrolyse damaged organelles in a cell
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q5 · Radioactively-labelled amino acids were introduced into a tracheal cell that uses them to…
5 Radioactively-labelled amino acids were introduced into a tracheal cell that uses them to make mucus (a glycoprotein). 1 2 3 4 What route will the amino acids take? first last A 1 2 3 4 B 1 4 3 2 C 4 1 2 3 D 4 3 2 1
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q6 · Which structures are present in a Vibrio cholerae cell?
6 Which structures are present in a Vibrio cholerae cell? circular 80S DNA ribosomes B A D C cell wall
Mark scheme: D
More questions on Cells as the basic units of living organisms
Q7 · The colour of a positive Benedict’s test is due to the formation of copper oxide
7 The colour of a positive Benedict’s test is due to the formation of copper oxide. The mass of copper oxide is proportional to the mass of reducing sugar present. Samples of fruit juice were tested for the presence of reducing sugars and non-reducing sugars using the Benedict’s test. The results show the mass of copper oxide after boiling with Benedict’s solution and after acid hydrolysis and boiling with Benedict’s solution. Which sample contained the most non-reducing sugar? mass of precipitate / mg after boiling with after acid hydrolysis and Benedict’s solution boiling with Benedict’s solution A 20 20 B 30 45 C 50 55 D 65 75
Mark scheme: B
Q8 · Which diagram shows the bond linking the individual units of both cellulose and glycogen?
8 Which diagram shows the bond linking the individual units of both cellulose and glycogen? A B C D H C O P O C C N C C C O C C C O C O O
Mark scheme: D
Q9 · Which row describes a triglyceride?
9 Which row describes a triglyceride? hydrophilic | S9UPS In A J J B J x c x J D x x key JY correct X not correct
Mark scheme: C
Q10 · The diagrams show the amino acid serine
10 The diagrams show the amino acid serine. Which circled area is different in all other amino acids? A B H H H H N H N H HO C C C OH HO C C C OH O H H O H H C D H H H H N H N H HO C C C OH HO C C C OH O H H O H H
Mark scheme: C
Q11 · As a frozen lake warms after a cold winter, mineral nutrients are brought to the surface
11 As a frozen lake warms after a cold winter, mineral nutrients are brought to the surface. Which properties of water contribute to this process? 1 Its greatest density is at 4 °C. 2 It has high specific heat capacity. 3 It is a solvent. 4 Its molecules form hydrogen bonds. A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4
Mark scheme: A
Q12 · Which statements describe some enzyme actions?
12 Which statements describe some enzyme actions? 1 Enzymes hold reacting molecules in such a way that their reactive groups are brought close together. 2 In an enzyme-catalysed reaction, more molecules have sufficient energy to react than in the absence of the enzyme. 3 Reactions catalysed by enzymes take place at a lower temperature than they would without the enzyme. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: A
Q13 · The diagram shows the mass of product formed over time in three reactions using the same…
13 The diagram shows the mass of product formed over time in three reactions using the same substrate and enzyme. The volumes of substrate, enzyme and temperature were kept constant in each reaction. 1 2 mass of product 3 00 time Which statement explains the difference in these reactions? A The pH in reactions 2 and 3 has denatured the enzyme. B There is a non-competitive inhibitor present in reaction 3. C There is the highest concentration of enzyme in reaction 1. D There is the highest concentration of substrate in reaction 1.
Mark scheme: C
Q14 · Tyrosinase is an enzyme that catalyses the conversion of the amino acid tyrosine into the…
14 Tyrosinase is an enzyme that catalyses the conversion of the amino acid tyrosine into the black pigment melanin. It is responsible for the black fur colour of some rabbits. A group of rabbits kept at 30 °C resulted in 90% of the rabbits with light fur colour. A second group of rabbits kept at 10 °C resulted in 90% of the rabbits with black fur colour. Which hypothesis is supported by these results? A An inhibitor is present in rabbit skin cells that can bind strongly to tyrosinase when the external temperature is 30 °C. B At 10 °C external temperature there are fewer tyrosinase-tyrosine complexes formed and less melanin is produced. C Tyrosinase is an enzyme that is coded for by a gene that is switched off when the external temperature is 10 °C. D Tyrosinase is a temperature-sensitive molecule that is only activated when the external temperature is 30 °C.
Mark scheme: A
Q15 · Which descriptions are correct for transport across cell surface membranes?
15 Which descriptions are correct for transport across cell surface membranes? active processes passive processes A active transport exocytosis and osmosis B endocytosis and exocytosis facilitated diffusion and osmosis C exocytosis and active transport osmosis and endocytosis D facilitated diffusion and exocytosis endocytosis and diffusion
Mark scheme: B
Q16 · The stages of an investigation using plant tissue are listed below
16 The stages of an investigation using plant tissue are listed below. ● A freshly cut slice of plant tissue was rinsed in distilled water, dried and weighed. ● This slice was placed in a solution with a water potential of – 4 arbitrary units for thirty minutes. ● The slice was removed from the solution, dried and reweighed. ● The mass of the slice was the same as its original mass. Which conclusions can be drawn from this investigation? 1 The water potential of the cells of the plant tissue is – 4 arbitrary units. 2 The cell sap of the plant tissue has a lower water potential than the surrounding solution. 3 There has been no net movement of water. 4 The cell wall of the plant tissue will not be in contact with the cell membrane. A 1 and 2 B 1 and 3 C 2 and 4 D 3 and 4
Mark scheme: B
Q17 · What explains the effect on a red blood cell of being placed into pure water?
17 What explains the effect on a red blood cell of being placed into pure water? A Less water leaves the cell than enters it, so the cell shrinks. B More water enters the cell than leaves it, so the cell swells and bursts. C Water enters the cell and none leaves it, so the cell swells and bursts. D Water enters the cell and more leaves it, so the cell shrinks.
Mark scheme: B
Q18 · Which statements about a diploid cell are correct?
18 Which statements about a diploid cell are correct? 1 can divide by mitosis to repair itself 2 has two complete sets of chromosomes 3 can undergo a reduction division to form haploid cells 4 can undergo mitotic division to allow growth to occur A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: D
More questions on Replication and division of nuclei and cells
Q19 · Which metabolic processes will be very active in a cell that has just completed…
19 Which metabolic processes will be very active in a cell that has just completed cytokinesis? 1 ATP formation 2 DNA replication 3 protein synthesis A 1, 2 and 3 B 1 and 3 only C 2 only D 3 only
Mark scheme: B
More questions on Replication and division of nuclei and cells
Q20 · What occurs during DNA replication and transcription and translation?
20 What occurs during DNA replication and transcription and translation? 1 ATP provides energy. 2 Condensation reactions occur to form a polymer. 3 Hydrogen bonds form between purine and pyrimidine bases. A 1, 2 and 3 B 1 and 2 only C 2 only D 3 only
Mark scheme: A
More questions on Structure of nucleic acids and replication of DNA
Q21 · Ricin is a toxic protein which inactivates ribosomes
21 Ricin is a toxic protein which inactivates ribosomes. Which effect will this have on protein synthesis? A Amino acids will be unable to bind to the binding sites on specific tRNA molecules. B Anticodons on mRNA molecules will not base pair to codons on tRNA molecules. C Peptide bonds will not form between adjacent amino acids in the growing polypeptide. D RNA nucleotides will be unable to join by condensation reactions to form rRNA.
Mark scheme: C
Q22 · Which row shows two pairs of nucleotide bases in a molecule of DNA?
22 Which row shows two pairs of nucleotide bases in a molecule of DNA? first base pair second base pair number of number of bases present bases present hydrogen bonds hydrogen bonds A AT 2 CG 2 B AT 2 CG 3 C TA 3 GC 2 D TA 3 GC 3
Mark scheme: B
More questions on Structure of nucleic acids and replication of DNA
Q23 · What is the role of the Casparian strip?
23 What is the role of the Casparian strip? A to act as a site for active transport of ions into the xylem B to increase root pressure, increasing transpiration C to lower the water potential in the xylem D to prevent water moving back into the cortex from the xylem
Mark scheme: D
Q24 · Sucrose is loaded into companion cells and phloem sieve tube elements by active transport…
24 Sucrose is loaded into companion cells and phloem sieve tube elements by active transport and diffusion using transport proteins and plasmodesmata. Which row shows how sucrose is loaded? active transport diffusion transport proteins plasmodesmata A into companion cell into phloem sieve into companion cell into phloem sieve tube element tube element B into companion cell into phloem sieve into phloem sieve into companion cell tube element tube element C into phloem sieve into companion cell into companion cell into phloem sieve tube element tube element D into phloem sieve into companion cell into phloem sieve into companion cell tube element tube element
Mark scheme: A
Q25 · Which changes to the water potential and the volume of liquid in the phloem occur when…
25 Which changes to the water potential and the volume of liquid in the phloem occur when sucrose is transferred from leaves into phloem sieve tubes to be transported to a sink? water potential volume of liquid in phloem sieve in phloem tubes becomes sieve tubes A less negative decreased B less negative increased C more negative decreased D more negative increased
Mark scheme: D
Q26 · The diagram shows the results of an experiment using leaves with the same surface area…
26 The diagram shows the results of an experiment using leaves with the same surface area from two different species. Each leaf was left on a balance in daylight in a closed room and their mass recorded at 1 hour intervals. mass of leaf leaf X leaf Y 0 1 2 3 4 5 time / hours Which features of leaf X could explain these results? 1 thinner cuticle 2 sunken stomata 3 ability to roll the leaf 4 no trichomes on the leaf A 1 and 3 B 1 and 4 C 2 and 3 D 1 only
Mark scheme: C
Q27 · Which components of blood are found in tissue fluid?
27 Which components of blood are found in tissue fluid? glucose proteins blood calls A v v v B v v x Cc v x v D x v v key /¥ = present X = absent
Mark scheme: A
Q28 · Which reactions take place in a capillary in an active tissue?
28 Which reactions take place in a capillary in an active tissue? 1 carbon dioxide and water are formed from hydrogencarbonate ions and hydrogen ions 2 carbonic acid is formed from carbon dioxide and water 3 carbaminohaemoglobin is formed from carbon dioxide and haemoglobin 4 haemoglobin and hydrogen ions are formed from haemoglobinic acid A 1 and 2 B 1 and 3 C 2 and 3 D 2 and 4
Mark scheme: C
Q29 · What happens to the atrioventricular valves and to the semilunar valves during atrial…
29 What happens to the atrioventricular valves and to the semilunar valves during atrial systole and ventricular systole? atrial systole ventricular systole atrioventricular semilunar atrioventricular semilunar valves valves valves valves A open closed closed open B open closed open open C closed open closed closed D closed open open closed
Mark scheme: A
Q30 · Red blood cells may contain a molecule known as 2,3-bisphophoglycerate (2,3BPG)
30 Red blood cells may contain a molecule known as 2,3-bisphophoglycerate (2,3BPG). When 2,3BPG binds to haemoglobin a higher partial pressure of oxygen is needed to bring about 50% saturation of haemoglobin with oxygen. Which statements about the effect of 2,3BPG are correct? 1 2,3BPG in red blood cells causes the oxygen dissociation curve to shift to the right. 2 The binding of 2,3BPG to haemoglobin reduces the Bohr effect. 3 The binding of 2,3BPG to haemoglobin lowers the affinity of the haemoglobin for oxygen. 4 When 2,3BPG is absent, oxyhaemoglobin is less likely to unload oxygen. A 1 and 2 B 1 and 3 C 2 and 3 D 3 and 4
Mark scheme: B
Q31 · Which row about the human gas exchange system is correct?
31 Which row about the human gas exchange system is correct? trachea bronchus alveolus A cartilage present present absent B ciliated epithelium absent present absent C goblet cells present absent absent D smooth muscle present present present
Mark scheme: A
Q32 · Which of the effects are caused by breathing in both carbon monoxide and nicotine from…
32 Which of the effects are caused by breathing in both carbon monoxide and nicotine from cigarette smoke? 1 increased heart rate 2 increased risk of cardiovascular disease 3 increased risk of emphysema 4 increased risk of lung cancer A 1, 2 and 3 B 2, 3 and 4 C 1 and 2 only D 3 and 4 only
Mark scheme: C
Q33 · Which statements about chronic obstructive pulmonary disease (COPD) are correct?
33 Which statements about chronic obstructive pulmonary disease (COPD) are correct? 1 The disease can often be reversed by treatment. 2 The patient’s symptoms normally do not change. 3 The patient is normally over 30 years old. 4 The patient coughs a lot, bringing up mucus. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: D
Q34 · Why is it necessary for a person with a bacterial infection to take antibiotics at evenly…
34 Why is it necessary for a person with a bacterial infection to take antibiotics at evenly spaced time intervals? A to increase the concentration of antibiotic slowly to a level which is lethal to the bacteria B to maintain a concentration of antibiotic in the body which is lethal to the bacteria C to prevent the development of resistant strains of bacteria D to select and kill the resistant strains of bacteria
Mark scheme: B
Q35 · Which statement is correct for a neutrophil?
35 Which statement is correct for a neutrophil? A They are found in tissues and secrete cytokines in response to infection. B They can leave the blood and accumulate at sites of inflammation. C They can leave the blood and secrete cytotoxins when exposed to damaged cells. D They circulate in the blood and present antigens in response to infection.
Mark scheme: B
Q36 · What describes artificial passive immunity?
36 What describes artificial passive immunity? A protection against a pathogen by an injection of antibodies B protection against a pathogen by drinking colostrum containing antibodies C stimulation of lymphocytes by antigens contained in a vaccine D stimulation of lymphocytes by antigens on the surface of invading pathogens
Mark scheme: A
Q37 · Which statements correctly describe lymphocytes?
37 Which statements correctly describe lymphocytes? 1 Each B-lymphocyte has the ability to make several types of antibody molecules. 2 Some B-lymphocytes and T-lymphocytes become memory cells. 3 Plasma cells secrete antibodies into the blood plasma. 4 Some T-lymphocytes stimulate macrophages to kill infected cells. A 1, 2, 3 and 4 B 1, 2 and 3 only C 2, 3 and 4 only D 1 and 4 only
Mark scheme: C
Q38 · Which group could be a population?
38 Which group could be a population? A all the animals and plants on an isolated island B all the birds counted in one day in a garden C all the bacteria in a colony of Bacillus subtilis D all the insects occupying three hectares of farmland
Mark scheme: C
Q39 · The diagram shows the flow of energy through a food chain
39 The diagram shows the flow of energy through a food chain. key sunlight energy loss 3000 kJ m–2 y–1 1 × 106 kJ m–2 y–1 green plants herbivore carnivore 27 000 kJ m–2 y–1 What percentage of the energy is used by the green plants for photosynthesis? A 0.03% B 0.30% C 2.70% D 3.00%
Mark scheme: D
More questions on Photosynthesis as an energy transfer process
Q40 · Anaerobic bacteria are found in large numbers in waterlogged soils
40 Anaerobic bacteria are found in large numbers in waterlogged soils. Which effect does this have on soil fertility and why? soil fertility reason A decreased bacteria convert nitrate to ammonia B decreased bacteria convert nitrate to nitrogen gas C increased bacteria cause decomposition D increased bacteria cause nitrogen fixation
Mark scheme: B
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
5Transport mechanisms4Movement into and out of cells3The gas exchange system3Carbohydrates and lipids2Factors that affect enzyme action2Replication and division of nuclei and cells2Structure of nucleic acids and replication of DNA2The immune system2Transport of oxygen and carbon dioxide2Antibiotics1Antibodies and vaccination1Classification1Conservation1Mode of action of enzymes1Photosynthesis as an energy transfer process1Protein synthesis1Proteins1Testing for biological molecules1The circulatory system1The heart1The microscope in cell studies1Water1What you needed in this session
Cambridge’s own grade thresholds for 2015 Oct/Nov, Paper 1 · Variant 2. A higher threshold means an easier paper — the bar moves with how the cohort did.