Cambridge A Level Biology 9700 — 2024 Oct/Nov Paper 1 · Variant 3
9700/13/O/N/24 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper20 pages




















Mark scheme3 pages
Answers below. Sit the paper first if you are practising.



Questions as text
Q1 · Which steps are needed to find the actual width of a xylem vessel viewed in transverse…
1 Which steps are needed to find the actual width of a xylem vessel viewed in transverse section using a 10 objective lens? 1 Convert from mm to m by multiplying by 10–3. 2 Calibrate the eyepiece graticule using a stage micrometer on a 4 objective lens. 3 Measure the width of the xylem vessel using an eyepiece graticule. 4 Multiply the number of eyepiece graticule units by the calibration of the eyepiece graticule. A 1, 2, 3 and 4 B 1 and 2 only C 2, 3 and 4 only D 3 and 4 only
Mark scheme: D
Q2 · Which cell structure is found in human cells and typical plant cells?
2 Which cell structure is found in human cells and typical plant cells? A 70S ribosomes B cilia C plasmodesmata D tonoplast
Mark scheme: A
More questions on Cells as the basic units of living organisms
Q3 · Which statements are correct for a typical prokaryotic cell?
3 Which statements are correct for a typical prokaryotic cell? 1 It contains 70S ribosomes. 2 It contains a cellulose cell wall. 3 It contains circular DNA. 4 It is up to 5 m in diameter. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q4 · The diagram shows a typical animal cell
4 The diagram shows a typical animal cell. X What is the function of the membrane system labelled X? A lipid synthesis only B protein synthesis and transport C protein synthesis only D protein transport only
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q5 · What describes a lysosome?
5 What describes a lysosome? A a vesicle containing enzymes, enclosed by a double membrane, that is budded off the endoplasmic reticulum B a vesicle containing hydrolytic enzymes and surrounded by a single membrane, found only in phagocytes C a vesicle enclosed by a single membrane, containing several different hydrolytic enzymes that may act inside or outside the cell D a vesicle surrounded by a double membrane, containing enzymes which can hydrolyse damaged organelles in a cell
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q6 · The diagram shows a triglyceride
6 The diagram shows a triglyceride. O H H H H H H H H H H C C C C C C C C C C H H C O H H H H H H H H H O H H H H H H H H H C C C C C C C C C C H H C O H H H H H H H H H O H H H H H H H H C C C C C C C H C C H C O H H H H H C H H H H What will be the products after hydrolysis of this triglyceride? A 1 molecule of glycogen, 3 unsaturated fatty acids and 3 molecules of water B 1 molecule of glycerol, 2 saturated fatty acids and 1 unsaturated fatty acid C 1 molecule of glycogen, 2 saturated fatty acids and 1 unsaturated fatty acid D 1 molecule of glycerol, 1 saturated fatty acid, 2 unsaturated fatty acids and 3 molecules of water
Mark scheme: B
Q7 · Which description lists all the components of a human haemoglobin molecule?
7 Which description lists all the components of a human haemoglobin molecule? A four polypeptides that are all the same and one haem group B four polypeptides that are not all the same and one haem group C four polypeptides that are all the same and four haem groups D four polypeptides that are not all the same and four haem groups
Mark scheme: D
Q8 · HIV-1 protease is an enzyme produced by the HIV virus
8 HIV-1 protease is an enzyme produced by the HIV virus. Two identical chains of 99 amino acids form the enzyme. In each chain, amino acids 25, 26 and 27 in the sequence form part of the active site. Which orders of protein structure control the shape of the active site? A primary, secondary, tertiary and quaternary B primary, secondary and tertiary only C primary and quaternary only D quaternary only
Mark scheme: A
Q9 · Which statements are correct reasons for how animals cool down in hot environments using…
9 Which statements are correct reasons for how animals cool down in hot environments using latent heat of vaporisation of water? 1 Some animals lie down and roll in wet soil. 2 Fish move into deeper water. 3 Some animals lick their fur to make it wet. 4 Some animals breathe quickly with a wet tongue hanging out of their mouth. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: C
Q10 · Two different enzymes, P and Q, are investigated to find the optimum pH for each enzyme
10 Two different enzymes, P and Q, are investigated to find the optimum pH for each enzyme. The results show that P works only in acidic conditions. Q has an optimum pH which is slightly alkaline. Which graph shows the correct results for P and Q? A B Q P Q substrate rate of P concentration reaction at 1 minute 0 7 14 0 7 14 pH pH C D 14 7 Q pH 7 P pH P Q 0 0 product concentration rate of reaction at 1 minute
Mark scheme: B
Q11 · A student investigated the effect of substrate concentration on the rate of an…
11 A student investigated the effect of substrate concentration on the rate of an enzyme-catalysed reaction. The student plotted the results in a graph. 40 30 reaction rate 20 / mol dm–3 s–1 10 0 0 10 20 30 40 50 substrate concentration / mol dm–3 What is the Km for this enzyme-catalysed reaction? A 12 mol dm–3 B 15 mol dm–3 s–1 C 30 mol dm–3 s–1 D 50 mol dm–3
Mark scheme: A
Q12 · Which statements could be used to describe enzyme molecules and antibody molecules?
12 Which statements could be used to describe enzyme molecules and antibody molecules? 1 Hydrogen bonds stabilise the structure of the protein and are important for it to function efficiently. 2 Hydrophilic R-groups point in to the centre of the molecule and cause it to curl into a spherical shape. 3 The tertiary structure of the protein molecule plays an important role in the functioning of the protein. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: C
Q13 · Which description identifies a reversible, non-competitive enzyme inhibitor?
13 Which description identifies a reversible, non-competitive enzyme inhibitor? A It can attach to the active site. B It can attach to a site other than the active site. C It can attach to the active site and another site simultaneously. D It can attach to either the active site or another site.
Mark scheme: B
Q14 · Before mitochondria are extracted from cells for microscopy, they are usually kept in a…
14 Before mitochondria are extracted from cells for microscopy, they are usually kept in a 0.25 mol dm–3 sucrose solution. Why is the sucrose solution used? A to act as a solvent B to enable the rate of reaction of the mitochondria to be determined C to prevent the mitochondria from changing in dimension D to provide a source of energy
Mark scheme: C
Q15 · The photomicrograph shows a type of blood cell
15 The photomicrograph shows a type of blood cell. Which statements about these cells are correct? 1 Oxygen diffuses through the phospholipid bilayer. 2 Sodium ions diffuse through the phospholipid bilayer. 3 Water passes in and out of these cells by osmosis. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: C
Q16 · Which row is correct for parts of a phospholipid molecule?
16 Which row is correct for parts of a phospholipid molecule? can be saturated can also be found or unsaturated in a triglyceride A head tail B tail head C head head D tail tail
Mark scheme: D
Q17 · A student filled dialysis tubing with a sucrose solution and knotted both ends
17 A student filled dialysis tubing with a sucrose solution and knotted both ends. This formed a cylinder with a length of 5.0 cm and a radius of 2.0 cm. What is the surface area to volume ratio for this cylinder of dialysis tubing? A 0.7 : 1.0 B 1.0 : 1.0 C 1.4 : 1.0 D 2.5 : 1.0
Mark scheme: C
Q18 · Which process does not involve mitosis?
18 Which process does not involve mitosis? A asexual reproduction B growth of unicellular organisms C repair of tissues by cell replacement D replacement of damaged or dead cells
Mark scheme: B
More questions on Replication and division of nuclei and cells
Q19 · The photomicrograph shows cells in an onion root tip
19 The photomicrograph shows cells in an onion root tip. X Y Z Which labelled cells are in anaphase, metaphase and prophase? anaphase metaphase prophase A X Y Z B Y Z X C Z X Y D Z Y X
Mark scheme: D
Q20 · The diagram shows an outline of the mitotic cell cycle
20 The diagram shows an outline of the mitotic cell cycle. 1 2 cytokinesis 3 Which numbered stages of the cell cycle include a period of time when each chromosome consists of sister chromatids joined by a centromere? A 1 and 2 B 1 and 3 C 2 and 3 D 2 only
Mark scheme: A
More questions on Replication and division of nuclei and cells
Q21 · The diagram shows part of a nucleic acid molecule
21 The diagram shows part of a nucleic acid molecule. A X G U C What is the name of bond X? A glycosidic bond B hydrogen bond C peptide bond D phosphodiester bond
Mark scheme: D
More questions on Structure of nucleic acids and replication of DNA
Q22 · XNA is a laboratory-made nucleic acid
22 XNA is a laboratory-made nucleic acid. XNA is made of nucleotides in which one component has been replaced by chemical X. The chemical X is organic but is not found in nature. The part of the molecule responsible for coding is not changed. Which component of a DNA or RNA nucleotide has been replaced by the organic chemical X? A five-carbon sugar B phosphate group C purine base D pyrimidine base
Mark scheme: A
More questions on Structure of nucleic acids and replication of DNA
Q23 · Which strand of DNA does RNA polymerase bind to?
23 Which strand of DNA does RNA polymerase bind to? A lagging strand B leading strand C non-transcribed strand D template strand
Mark scheme: D
Q24 · Which processes occur during the formation of messenger RNA?
24 Which processes occur during the formation of messenger RNA? 1 condensation 2 polymerisation 3 replication 4 transcription A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: B
Q25 · The anticodon for the amino acid tryptophan is ACC
25 The anticodon for the amino acid tryptophan is ACC. What shows a template DNA sequence that includes the DNA triplet for tryptophan? A UGG CGU CCG B GCU GAC ACG C CTT TGG ATG D CCT ACC CAT
Mark scheme: D
Q26 · A student drew a plan diagram of some plant tissue
26 A student drew a plan diagram of some plant tissue. The diagram is shown. It contains a mistake in the way that it is drawn. R The maximum width of R is 15 mm on the diagram and its actual width is 250 m. The student was asked to draw a scale bar on their diagram. Which row is correct? length of scale bar part of the location of in mm to correctly plant drawn drawing mistake represent 100 m A root phloem 6 B root xylem 170 C stem phloem 170 D stem xylem 6
Mark scheme: D
Q27 · Four students have drawn and labelled part of a structure seen on an electron micrograph
27 Four students have drawn and labelled part of a structure seen on an electron micrograph. Which student has labelled their drawing correctly? A B vacuole mitochondria mitochondria sieve plate sieve plate thin cytoplasm C D nucleus chloroplast sieve plate sieve plate thin cytoplasm thin cytoplasm
Mark scheme: A
Q28 · The diagram shows some structures used for transport in the phloem
28 The diagram shows some structures used for transport in the phloem. cell Y companion cell Z cell direction of phloem sieve tube transport long distance Which statement is correct? A Cell Y is the sink cell. B Cell Z can be above or below cell Y in the plant. C Cell Z must be in a photosynthetic tissue. D Cell Y allows glucose to move to the sieve tube via the companion cell.
Mark scheme: B
Q29 · The diagram shows a section through a root of a dicotyledonous plant
29 The diagram shows a section through a root of a dicotyledonous plant. soil particle root hair root cell xylem cell vessel Casparian strip Which statement correctly describes the movement of water and solutes through this root? A A layer of suberin causes water and solutes to move from the apoplast pathway into the symplast pathway. B A layer of suberin causes water and solutes to move from the symplast pathway into the apoplast pathway. C The tonoplast causes water and solutes to move from the symplast pathway into the apoplast pathway. D The tonoplast causes water and solutes to move from the apoplast pathway into the symplast pathway.
Mark scheme: A
Q30 · The graph shows the effect of different partial pressures of carbon dioxide (CO2) on the…
30 The graph shows the effect of different partial pressures of carbon dioxide (CO2) on the oxygen dissociation curve for haemoglobin. 100 80 partial pressure CO partial pressure CO2 partial pressure CO2 1.0 1.0 kPa 1.0 kPa kPa 60 percentage partial pressure CO partial pressure CO2 partial pressure CO2 saturation of 1.5 1.5 kPa 1.5 kPa kPa haemoglobin with oxygen 40 20 0 0 1 2 3 4 5 6 7 8 9 10 11 12 partial pressure of oxygen / kPa What is the change in percentage oxygen saturation of haemoglobin at a partial pressure of oxygen of 6 kPa as the partial pressure of carbon dioxide changes from 1.0 kPa to 1.5 kPa? A –26% B –20% C 20% D 46%
Mark scheme: B
Q31 · What happens in the heart at the start of ventricular diastole?
31 What happens in the heart at the start of ventricular diastole? A The semilunar valves open. B The atrioventricular valves open. C The pressure in the atria rises above the pressure in the ventricles. D The pressure in the left atrium rises more than the pressure in the right atrium.
Mark scheme: B
Q32 · The electron micrograph shows a longitudinal section through a blood vessel
32 The electron micrograph shows a longitudinal section through a blood vessel. blood vessel Which type of blood vessel is shown? A arteriole B capillary C vein D venule
Mark scheme: B
Q33 · A student drew a sketch to show the formation of tissue fluid
33 A student drew a sketch to show the formation of tissue fluid. Which label is correct? A D blood enters higher volume capillary and capillary of blood pressure increases returns to vein tissues B C red blood cells higher water potential in and water move tissue fluid so water moves into tissues back into the capillary
Mark scheme: C
Q34 · Which structures are present in the trachea and also in all bronchioles?
34 Which structures are present in the trachea and also in all bronchioles? 1 cartilage 2 smooth muscle 3 epithelial cells A 1, 2 and 3 B 1 only C 2 and 3 only D 2 only
Mark scheme: C
Q35 · The photomicrograph shows a section through part of the gas exchange system
35 The photomicrograph shows a section through part of the gas exchange system. Which tissue can be seen? A cartilage B ciliated epithelium C smooth muscle D squamous epithelium
Mark scheme: D
Q36 · What is the function of the goblet cells in the gas exchange system?
36 What is the function of the goblet cells in the gas exchange system? A to increase the surface area B to move mucus C to release mucus D to trap dust and pathogens
Mark scheme: C
Q37 · Which organisms have cell walls that can be affected by penicillin?
37 Which organisms have cell walls that can be affected by penicillin? 1 bacteria 2 protoctists 3 viruses A 1 and 2 B 1 and 3 C 1 only D 2 and 3
Mark scheme: C
Q38 · Each year, there are 462 000 deaths from malaria in children under 5 years old globally
38 Each year, there are 462 000 deaths from malaria in children under 5 years old globally. Insecticide-treated nets could prevent 50% of malaria cases and reduce deaths of children under 5 years old by 18%. How many children could be saved by using insecticide-treated nets? A 41 580 B 83 160 C 231 000 D 332 640
Mark scheme: B
Q39 · Which row is correct?
39 Which row is correct? involved in secrete phagocytosis antibodies A T-lymphocytes B-lymphocytes B T-lymphocytes T-lymphocytes C B-lymphocytes B-lymphocytes D B-lymphocytes T-lymphocytes
Mark scheme: A
Q40 · Four steps that occur during the primary immune response to a pathogen are listed
40 Four steps that occur during the primary immune response to a pathogen are listed. P B-lymphocytes divide by mitosis. Q T-helper cells interact with macrophages that have digested pathogens. R Plasma cells secrete antibodies. S T-helper cells activate other lymphocytes. These steps can be arranged in the sequence in which they occur. Which step occurs third in the sequence? A P B Q C R D S
Mark scheme: A
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
4Factors that affect enzyme action3Movement into and out of cells3Protein synthesis3Proteins3The gas exchange system3Replication and division of nuclei and cells2Structure of nucleic acids and replication of DNA2The circulatory system2The immune system2The microscope in cell studies2Transport mechanisms2Antibiotics1Carbohydrates and lipids1Chromosome behaviour in mitosis1Fluid mosaic membranes1Infectious diseases1Structure of transport tissues1The heart1Transport of oxygen and carbon dioxide1Water1What you needed in this session
Cambridge’s own grade thresholds for 2024 Oct/Nov, Paper 1 · Variant 3. A higher threshold means an easier paper — the bar moves with how the cohort did.