Cambridge A Level Biology 9700 — 2017 Oct/Nov Paper 1 · Variant 3

Question 1

1 Which statement about the light microscope is correct? A As the smallest distance to see two points as distinct separate points decreases, the resolution also decreases. B If the resolution is 220 nm, then a bacterium 0.2 µm in diameter will not be visible. C If the wavelength of light is 600 nm, then two membranes 300 nm apart will be visible as two distinct membranes. D Using visible light of a longer wavelength, such as red light, will improve the resolution.

Accepted Answer

B

Question 2

2 The diagram shows a stage micrometer scale viewed with an eyepiece graticule, using a magnification of ×200. 0.1 mm 0 10 20 30 40 50 60 70 80 90 100 Using the same magnification, a chloroplast is measured as 4 eyepiece graticule divisions long. How long is the chloroplast? A 1.0 × 101 µm B 4.0 × 102 µm C 2.5 × 10–1 µm D 2.5 × 10–2 µm

Accepted Answer

A

Question 3

3 A cell was supplied with cytosine labelled with radioactive carbon. In which cell structure would radioactivity be detected first? A endoplasmic reticulum B Golgi body C nucleus D ribosome

Accepted Answer

C

Question 4

4 The diagram shows some similarities between chloroplasts, mitochondria and typical prokaryotes. 1 2 3 4 5 Which row is correct? 1 2 3 4 5 A chloroplasts circular DNA mitochondria 80S ribosomes prokaryotes B chloroplasts 80S ribosomes mitochondria circular DNA prokaryotes C prokaryotes circular DNA mitochondria circular DNA chloroplasts D prokaryotes 70S ribosomes chloroplasts 80S ribosomes mitochondria

Accepted Answer

C

Question 5

5 Which statement supports the fact that mature plant cells can carry out the same role as lysosomes? A A range of hydrolytic enzymes can be found within mature plant vacuoles. B Glycogen, found within vesicles, can be hydrolysed to glucose molecules. C Single membrane-bound vesicles are formed from plant Golgi bodies. D Vesicles, formed from smooth endoplasmic reticulum, contain enzymes.

Accepted Answer

A

Question 6

6 A student carried out four tests for biological molecules on a sample of milk. The tests and their results were as follows. ● Heating to 80 °C with Benedict’s solution gave a green colour. ● Adding Biuret solution gave a purple colour. ● Adding iodine solution gave an orange colour. ● Boiling with acid, followed by neutralisation, then heating to 80 °C with Benedict’s solution gave a brick red colour. Which conclusion about these results is correct? A only protein and reducing sugar present B only protein and non-reducing sugar present C only protein, reducing sugar and non-reducing sugar present D only starch, protein and sugar present

Accepted Answer

C

Question 7

7 The diagrams show four monosaccharides with the formula C6H12O6. 1 2 3 4 CH2OH CH2OH CH2OH CH2OH H O H H O OH H O H H O H H H H H OH H OH H H H OH HO HO OH HO H HO OH HO OH H OH H OH OH OH H H Which diagrams show glucose molecules? A 1 and 2 B 1 and 3 C 2 and 3 D 3 and 4

Accepted Answer

A

Question 8

8 Which bonds will be broken when a molecule of glycogen is broken down? 1 α-1, 4 2 β-1, 4 3 α-1, 6 4 β-1, 6 A 1, 2 and 3 B 1 and 3 only C 2, 3 and 4 D 2 and 4 only

Accepted Answer

B

Question 9

9 The diagram shows the amino acids in a polypeptide. key type of amino acid polar basic polar acidic Asp Arg Lys polar Cys Thr Lys Leu non-polar Pro Asn Arg Val Ser Asn Glu Lys Thr Arg Phe Met Lys Phe Gln Met Ala His Val Gln Met Ala His Asn Asp Ala Glu Cys Thr Ser C terminal end Tyr Ser Glu Asn Lys Ser Thr Ser Ser N terminal end Ser Ala Ala An enzyme catalyses the hydrolysis of any peptide bond between a non-polar amino acid and any polar amino acid. How many small peptides and single amino acids will be formed by the action of this enzyme? small single peptides amino acids A 6 1 B 8 1 C 12 3 D 13 4

Accepted Answer

D

Question 10

10 A person with diabetes is unable to make enough of the protein insulin. Some forms of diabetes can be treated by using insulin produced by animals. Scientists have compared the amino acids in insulin produced by animals to human insulin. Which level of protein structure were the scientists studying? A primary B secondary C tertiary D quaternary

Accepted Answer

A

Question 11

11 The diagrams show four fatty acids, each with a chain of 18 carbon atoms. Which fatty acid, as part of a phospholipid molecule, would contribute most to the fluidity of a cell surface membrane? COOH A COOH B COOH C COOH D

Accepted Answer

D

Question 12

12 Which levels of protein structure are maintained by disulfide bonds? A secondary, tertiary and quaternary B tertiary and quaternary only C quaternary only D tertiary only

Accepted Answer

B

Question 13

13 An experiment was conducted to investigate the effect of temperature on the activity of the enzyme β-glucosidase. The enzyme was tested when in solution (free) and when immobilised in alginate beads. The results are shown in the graph below. 120 100 80 β-glucosidase activity 60 / arbitrary units 40 immobilised 20 free enzyme enzyme 0 0 10 20 30 40 50 60 70 80 90 100 temperature / °C Which statement about the effect of immobilisation of β-glucosidase is correct? A It increases the kinetic energy of the enzyme. B It inhibits the activity of the enzyme. C It reduces the optimum temperature of the enzyme. D It stabilises the enzyme against denaturation.

Accepted Answer

D

Question 14

14 An investigation was carried out into the effect of an increasing concentration of substrate molecules on the rate of an enzyme-catalysed reaction. All other variables were standardised. Which statement is correct? A The rate increases to a maximum and then levels off. B The rate increases to an optimum and then decreases. C The value of Km will increase. D The Vmax will never be reached.

Accepted Answer

A

Question 15

15 Which features are correct for a competitive inhibitor of an enzyme-catalysed reaction?

rate of reaction

binds to changes shape | similar shape affected by
active site of enzyme to substrate concentration
of inhibitor
A J x J Jv key
B Jv x x Jv ¥ = correct
Cc x v v x X = incorrect
D x v x x

Accepted Answer

A

Question 16

16 Liver cells contain membrane-bound organelles called peroxisomes, which contain the enzyme catalase. This enzyme hydrolyses hydrogen peroxide into water and oxygen gas. A student cut two identical sized pieces of liver and placed one in a refrigerator at 5 °C and the other in a freezer at –18 °C. After 12 hours both pieces were raised to room temperature and placed in equal volumes of hydrogen peroxide. The liver that had been at –18°C produced bubbles of oxygen more rapidly than the liver that had been at 5 °C. Which statement explains why the liver that had been at –18 °C produced bubbles of oxygen more rapidly than the liver that had been at 5 °C? A At 5 °C the cell surface membrane allowed water to enter cells and dilute the catalase. B Freezing at –18 °C made the cell walls more permeable to hydrogen peroxide. C Ice crystals damaged the cell membranes of the liver cells at –18 °C. D The higher temperature had denatured some of the catalase.

Accepted Answer

C

Question 17

17 Which of these processes allow movement in both directions across cell surface membranes? 1 active transport 2 diffusion 3 facilitated diffusion 4 osmosis A 1, 2, 3 and 4 B 1 and 4 only C 2 and 3 only D 2 only

Accepted Answer

A

Question 18

18 The diagram shows an experiment in which two different cell surface membranes were joined to form a single large membrane. The outer surface of one membrane contained molecules of protein P and the outer surface of the other membrane contained molecules of protein Q. The positions of the two proteins in each membrane were observed just before they were joined together and 1 hour after they were joined. protein P protein Q + joined membrane after 1 hour Which statements are correct? 1 This provides evidence for the fluid mosaic model of cell membranes. 2 This shows that proteins can move freely in cell membranes. 3 This shows that the membrane is fluid but the proteins are not. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

B

Question 19

19 Which row describes osmosis across a cell surface membrane?

moves molecule
molecule uses energy down a concentration
moved from ATP gradient
A solute Jv Jv key
B solute v x JY = correct
Cc solvent x v X = incorrect
D solvent x x

Accepted Answer

C

Question 20

20 What describes a telomere? A a cell structure composed mainly of protein and involved in cell division B a protein that associates with DNA to help condense it C a region of DNA that links two sister chromatids together D a region of repetitive nucleotide sequences at the end of a chromatid

Accepted Answer

D

Question 21

21 Uncontrolled cell division can form tumours. Which statement is correct for tumour cells only? A Metaphase does not take place. B Cytokinesis does not occur. C Interphase takes less time. D They have mutated DNA.

Accepted Answer

C

Question 22

22 Which of these events are part of mitosis? 1 interphase 2 anaphase 3 cytokinesis A 1, 2 and 3 B 1 and 3 only C 1 only D 2 only

Accepted Answer

D

Question 23

23 Rifampicin is an antibiotic used to treat tuberculosis. It works by inhibiting RNA polymerase in bacteria. Which of these processes are prevented by this antibiotic? 1 DNA replication 2 transcription 3 translation A 1, 2 and 3 B 1 and 2 only C 2 and 3 only D 3 only

Accepted Answer

C

Question 24

24 A gene codes for the sequence of amino acids in a single polypeptide. Haemoglobin consists of two α-globins and two β-globins. How many genes are needed to code for a single haemoglobin molecule? A 1 B 2 C 4 D 8

Accepted Answer

B

Question 25

25 A single substitution in an allele of the gene coding for haemoglobin results in sickle cell haemoglobin. The mRNA sequence for three amino acids for normal haemoglobin is shown. CCUGAAGAG The mRNA sequence for sickle cell haemoglobin is shown. CCUGUAGAG The table shows some of the triplet codes for two amino acids. DNA triplet codes amino acid CTC Glu CTT Glu CAT Val CAC Val Which row is correct for the substituted DNA nucleotide of the allele and the substituted amino acid of the protein? DNA new amino nucleotide acid A A Glu B A Val C T Glu D T Val

Accepted Answer

B

Question 26

26 What is the minimum number of hydrogen bonds in a length of DNA containing 700 base pairs? A 350 B 700 C 1400 D 2100

Accepted Answer

C

Question 27

27 The photomicrograph is a section through a plant organ. Which label identifies the xylem vessels? A B C D

Accepted Answer

B

Question 28

28 Which of these statements correctly describe transport pathways in dicotyledonous plants? 1 In the apoplast pathway, water may move through plasmodesmata. 2 In the symplast pathway, water may move through intercellular spaces. 3 The apoplast pathway may be blocked by the Casparian strip. A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

Accepted Answer

D

Question 29

29 Mass flow is the bulk movement of materials from one place to another. Which vessels carry fluids by mass flow? 1 artery 2 phloem sieve tube 3 vein 4 xylem vessel A 1, 2, 3 and 4 B 1, 2 and 3 only C 1 and 3 only D 2 and 4 only

Accepted Answer

A

Question 30

30 Amino acids move from a phloem sieve tube element into a root cell. Which changes to the water potential and the volume of liquid in the phloem sieve tube element are correct? water potential volume of liquid A becomes higher decreases B becomes higher increases C becomes lower decreases D becomes lower increases

Accepted Answer

A

Question 31

31 The table shows the volume of water taken up over a 10 minute period for two species of plant, X and Y. water uptake / mm3 time / minutes X Y 2 4.2 1.2 4 7.8 2.3 6 10.9 3.7 8 13.3 4.4 10 16.9 4.9 Both plants were tested at the same time, in the same room and using identical potometers. A student concluded that Y was a xerophyte so lost less water. What feature of the experiment could bring this conclusion into doubt? A The student did not control air flow or temperature surrounding the plants. B The student did not leave the plants to acclimatise to their surroundings. C The student did not take measurements at 0 minutes. D The student did not take account of the area of leaves.

Accepted Answer

D

Question 32

32 What happens during left ventricular systole? A The atrioventricular node causes the immediate contraction of the ventricle, causing the atrioventricular valve to close. B The Purkyne tissue between the atrium and ventricle causes the ventricle to contract, closing the atrioventricular valve and opening the semilunar valve. C The sinoatrial node causes the atrium to stop contracting and the blood pressure in the ventricle to increase above that in the atrium. D The wave of excitation causes the ventricle to contract so that the blood pressure in the ventricle is higher than in the aorta, opening the semilunar valve.

Accepted Answer

D

Question 33

33 The photograph shows blood cells as seen using a high power light microscope. 1 3 2 Which row correctly identifies the different types of white blood cell? 1 2 3 A lymphocyte monocyte neutrophil B monocyte neutrophil macrophage C neutrophil monocyte lymphocyte D phagocyte lymphocyte monocyte

Accepted Answer

C

Question 34

34 Which of these processes are responsible for the Bohr shift? 1 Carbon dioxide reacts with haemoglobin to form carbaminohaemoglobin. 2 Carbon dioxide reacts with water to form carbonic acid. 3 Haemoglobinic acid is formed from the dissociation of carbonic acid. A 1, 2 and 3 B 1 only C 2 and 3 only D 3 only

Accepted Answer

C

Question 35

35 The photomicrograph shows a cross-section through a bronchus. X Y What is the function of the tissues X and Y? X Y A secrete mucus prevent collapse of the airway B support the airway dilate airway C trap dust and dirt secrete mucus D waft dust and dirt upwards constrict airway

Accepted Answer

D

Question 36

36 Which flow diagram correctly describes the effect of tar entering the lungs? carcinogens come into uncontrolled mass of cells A → mutation occurs → → contact with cell division produced DNA mucus goblet cells phagocytes causes accumulates B secrete more → → attracted by → irritation and causing mucus inflammation coughing infection goblet cells phagocytes mass of cells C secrete more → mutation occurs → attracted by → produced mucus inflammation phagocytes elastase uncontrolled D attracted by → mutation occurs → → destroys the cell division inflammation alveolar walls

Accepted Answer

A

Question 37

37 The antibiotic penicillin prevents the formation of cross-links between peptidoglycans during bacterial cell wall synthesis by blocking the enzyme transpeptidase. Which statements describe the action of penicillin on bacteria? 1 It is an enzyme inhibitor. 2 It weakens the bacterial cell wall. 3 It will work at any stage during the bacterial life cycle. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

B

Question 38

38 Which pathogens are spread by droplet infection? 1 Mycobacterium tuberculosis 2 Vibrio cholerae 3 Morbillivirus A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

C

Question 39

39 The flow diagram shows the events following activation of a T-lymphocyte by binding to antigens on an infected cell. T-lymphocyte helper cells killer cells B-lymphocytes X Y more activated killer cells Z memory cells Which row correctly identifies X, Y and Z? X Y Z A memory cells macrophages antibodies B memory cells memory cells plasma cells C neutrophils memory cells plasma cells D plasma cells neutrophil memory cells

Accepted Answer

B

Question 40

40 Smallpox was eradicated from the human population by a worldwide preventative programme. Which type of immunity was triggered in people who were treated as part of this programme? A artificial active immunity B artificial passive immunity C natural active immunity D natural passive immunity

Accepted Answer

A

Question paper20 pages

Mark scheme3 pages

Questions as text

Q1 · Which statement about the light microscope is correct?

Q2 · The diagram shows a stage micrometer scale viewed with an eyepiece graticule, using a…

Q3 · A cell was supplied with cytosine labelled with radioactive carbon

Q4 · The diagram shows some similarities between chloroplasts, mitochondria and typical…

Q5 · Which statement supports the fact that mature plant cells can carry out the same role as…

Q6 · A student carried out four tests for biological molecules on a sample of milk

Q7 · The diagrams show four monosaccharides with the formula C6H12O6

Q8 · Which bonds will be broken when a molecule of glycogen is broken down?

Q9 · The diagram shows the amino acids in a polypeptide

Q10 · A person with diabetes is unable to make enough of the protein insulin

Q11 · The diagrams show four fatty acids, each with a chain of 18 carbon atoms

Q12 · Which levels of protein structure are maintained by disulfide bonds?

Q13 · An experiment was conducted to investigate the effect of temperature on the activity of…

Q14 · An investigation was carried out into the effect of an increasing concentration of…

Q15 · Which features are correct for a competitive inhibitor of an enzyme-catalysed reaction?

Q16 · Liver cells contain membrane-bound organelles called peroxisomes, which contain the…

Q17 · Which of these processes allow movement in both directions across cell surface membranes?

Q18 · The diagram shows an experiment in which two different cell surface membranes were joined…

Q19 · Which row describes osmosis across a cell surface membrane?

Q20 · What describes a telomere?

Q21 · Uncontrolled cell division can form tumours

Q22 · Which of these events are part of mitosis?

Q23 · Rifampicin is an antibiotic used to treat tuberculosis

Q24 · A gene codes for the sequence of amino acids in a single polypeptide

Q25 · A single substitution in an allele of the gene coding for haemoglobin results in sickle…

Q26 · What is the minimum number of hydrogen bonds in a length of DNA containing 700 base pairs?

Q27 · The photomicrograph is a section through a plant organ

Q28 · Which of these statements correctly describe transport pathways in dicotyledonous plants?

Q29 · Mass flow is the bulk movement of materials from one place to another

Q30 · Amino acids move from a phloem sieve tube element into a root cell

Q31 · The table shows the volume of water taken up over a 10 minute period for two species of…

Q32 · What happens during left ventricular systole?

Q33 · The photograph shows blood cells as seen using a high power light microscope

Q34 · Which of these processes are responsible for the Bohr shift?

Q35 · The photomicrograph shows a cross-section through a bronchus

Q36 · Which flow diagram correctly describes the effect of tar entering the lungs?

Q37 · The antibiotic penicillin prevents the formation of cross-links between peptidoglycans…

Q38 · Which pathogens are spread by droplet infection?

Q39 · The flow diagram shows the events following activation of a T-lymphocyte by binding to…

Q40 · Smallpox was eradicated from the human population by a worldwide preventative programme

What was in this paper

What you needed in this session

Other variants, same session

This paper, other years