Cambridge A Level Biology 9700 — 2012 Oct/Nov Paper 1 · Variant 1
9700/11/O/N/12 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper16 pages
















Mark scheme2 pages
Answers below. Sit the paper first if you are practising.


Questions as text
Q1 · The diagram is a drawing from an electron micrograph of a cell
1 The diagram is a drawing from an electron micrograph of a cell. Which structure indicates that this is a secretory cell? A B C D
Mark scheme: B
More questions on Cells as the basic units of living organisms
Q2 · Four students were asked to suggest a set of four labels to add to a plan diagram of a…
2 Four students were asked to suggest a set of four labels to add to a plan diagram of a transverse section of a dicotyledonous leaf. Which student, A, B, C or D, suggested a correct set of labels? label 1 label 2 label 3 label 4 A lower phloem spongy palisade epidermis mesophyll mesophyll B phloem sieve upper spongy xylem vessel tubes epidermis mesophyll elements C spongy endodermis xylem vessel palisade mesophyll elements mesophyll D waxy cuticle xylem companion spongy cells mesophyll
Mark scheme: A
Q3 · Which of the following are found in both eukaryotic and prokaryotic cells?
3 Which of the following are found in both eukaryotic and prokaryotic cells? 1 cellulose 2 deoxyribose 3 lipids 4 ribose A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: D
More questions on Cells as the basic units of living organisms
Q4 · Which row correctly identifies all the locations of ribosomes in a eukaryotic cell?
4 Which row correctly identifies all the locations of ribosomes in a eukaryotic cell? attached to free in in attached to cytoplasm | mitochondria ER amelone in nucleus A Jv V V V y B WA x V x x Cc x V x V y D x x V V x key /¥ = present X = absent
Mark scheme: A
More questions on Cells as the basic units of living organisms
Q5 · Which statement about the light microscope is correct?
5 Which statement about the light microscope is correct? A As the smallest distance to see two points as distinct separate points decreases, the resolution also decreases. B If the resolution is 220 nm, then a bacterium 0.2 µm in diameter will not be visible. C If the wavelength of light is 600 nm, then two membranes 300 nm apart will be visible as two distinct membranes. D Using visible light of a longer wavelength, such as red light, will improve the resolution.
Mark scheme: B
Q6 · The diagram shows the ultrastructure of a cell from a dicotyledonous leaf
6 The diagram shows the ultrastructure of a cell from a dicotyledonous leaf. 5 µm What is the magnification? A × 280 B × 2800 C × 3570 D × 7000
Mark scheme: B
Q7 · Four students, 1, 2, 3 and 4, each carried out the reducing sugar test and the…
7 Four students, 1, 2, 3 and 4, each carried out the reducing sugar test and the non-reducing sugar test on a sucrose solution. Which observations demonstrate that they carried out the correct tests? observations for reducing observations for non- student sugar test reducing sugar test 1 no colour change changed colour 2 no colour change red 3 blue changed colour 4 blue red A 2 only B 3 only C 4 only D 1, 2, 3 and 4
Mark scheme: C
Q8 · Which row is correct for each of the molecules?
8 Which row is correct for each of the molecules? β-glucose collagen haemoglobin sucrose A hexose sugar structural contains the formed by with a molecular function, found in elements carbon, releasing a formula C6H12O6 tendons and hydrogen, iron, molecule of water blood vessel nitrogen and in a hydrolysis walls sulfur reaction B repeating a molecule each non-protein composed of two monomer of the consists of three haem group monosaccharides polysaccharide, polypeptide contains a central linked by a cellulose chains, each iron ion glycosidic bond containing a prosthetic group C monomer of the molecules lie has two identical formed by 1,6 glycosidic parallel to each α chains and two condensation of branches of the other, with cross- identical β chains two identical polysaccharide, links and monosaccharides glycogen staggered ends in its ring D polypeptide has all four levels digestion yields structure, the chains interact to of protein glucose and hydroxyl group of produce a fibrous structure and at fructose in equal carbon atom 1 is protein least four types of proportions above the plane bond of the ring
Mark scheme: D
Q9 · Which of the bonds will be last to break as the temperature of an enzyme is increased?
9 Which of the bonds will be last to break as the temperature of an enzyme is increased? A covalent B hydrogen C hydrophobic interactions D ionic
Mark scheme: A
Q10 · Which pair of monosaccharides form sucrose?
10 Which pair of monosaccharides form sucrose? CH2OH CH2OH H O H H O OH H H A OH H OH H OH OH OH H H OH H OH CH2OH CH2OH H O H H O H H H B OH H OH H OH OH OH OH H OH H OH CH2OH HOCH2 O CH2OH H O H H H OH C OH H H OH OH OH OH H H OH CH2OH HOCH2 O CH2OH H O OH H H OH D OH H H OH OH H OH H H OH
Mark scheme: C
Q11 · Which statement about triglycerides is correct?
11 Which statement about triglycerides is correct? A They are made up of three fatty acids combined with glycogen. B They are more saturated with hydrogen compared with phospholipids. C They form a bilayer in the membranes of cells. D They have a lower ratio of oxygen to carbon compared with carbohydrates.
Mark scheme: D
Q12 · Which molecules contain C=O bonds?
12 Which molecules contain C=O bonds? 1 amino acids 2 fatty acids 3 glycerol A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: A
Q13 · Which of the statements about polysaccharides can be used to describe both amylose and…
13 Which of the statements about polysaccharides can be used to describe both amylose and glycogen? 1 contains 1,4 glycosidic bonds 2 contains 1,6 glycosidic bonds 3 polymer of α–glucose A 1 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: B
Q14 · What is the effect of an enzyme in an enzyme-catalysed reaction?
14 What is the effect of an enzyme in an enzyme-catalysed reaction? A decreases both the activation energy and the energy yield B decreases the activation energy and has no effect on the energy yield C increases both the activation energy and the energy yield D increases the energy yield and decreases the activation energy
Mark scheme: B
Q15 · The diagram represents the fluid mosaic model of membrane structure
15 The diagram represents the fluid mosaic model of membrane structure. 3 2 1 4 6 5 Which two components contribute to the fluidity of the membrane? A 1 and 3 B 2 and 4 C 3 and 5 D 4 and 6
Mark scheme: D
Q16 · The graph shows how the rate of entry of glucose into a cell changes as the concentration…
16 The graph shows how the rate of entry of glucose into a cell changes as the concentration of glucose outside the cell changes. X rate of entry of glucose into the cell concentration of glucose outside the cell What is the cause of the plateau at X? A All the carrier proteins are saturated with glucose. B The carrier proteins are denatured and no longer able to function. C The cell has used up its supply of ATP. D The concentrations of glucose inside and outside the cell are equal.
Mark scheme: A
Q17 · A molecule can enter a cell by two different passive processes
17 A molecule can enter a cell by two different passive processes. Which process would increase the rate at which this molecule enters the cells? A diffusion B endocytosis C facilitated diffusion D osmosis
Mark scheme: C
Q18 · Which statement is incorrect for mitotic cell division?
18 Which statement is incorrect for mitotic cell division? A DNA is replicated semi-conservatively during mitosis. B DNA is normally unchanged from one generation of cells to the next. C The daughter cells have the potential to produce the same enzymes as the parent cell. D The same quantity of DNA is distributed to the nuclei of two new cells.
Mark scheme: A
More questions on Replication and division of nuclei and cells
Q19 · The diagram shows the chromosomes of one cell which has been squashed during mitosis
19 The diagram shows the chromosomes of one cell which has been squashed during mitosis. Which stage of mitosis is shown and what is the haploid chromosome number in this species? haploid chromosome stage of mitosis number A anaphase 5 B anaphase 10 C metaphase 5 D metaphase 10
Mark scheme: C
Q20 · What does the process of translation require?
20 What does the process of translation require? A DNA, free nucleotide bases and mRNA B DNA, mRNA and RNA polymerase C mRNA, ribosomes and RNA polymerase D mRNA, ribosomes and tRNA
Mark scheme: D
Q21 · Which features of DNA enable it to meet these requirements as a molecule of inheritance?
21 Which features of DNA enable it to meet these requirements as a molecule of inheritance? requirement of DNA molecule ability to remain ability to contain ability to transfer ability to replicate stable information information A complementary formation of mRNA sequence of sugar-phosphate base pairing for translation nucleotides backbone B formation of mRNA complementary sugar-phosphate sequence of for translation base pairing backbone nucleotides C sequence of sugar-phosphate complementary formation of mRNA nucleotides backbone base pairing for translation D sugar-phosphate sequence of formation of mRNA complementary backbone nucleotides for translation base pairing
Mark scheme: D
More questions on Structure of nucleic acids and replication of DNA
Q22 · Which diagram shows the bond linking the individual units of a nucleic acid?
22 Which diagram shows the bond linking the individual units of a nucleic acid? A B C D H C O C C C O C C N C C C O P O C O O
Mark scheme: C
More questions on Structure of nucleic acids and replication of DNA
Q23 · Which row correctly identifies xylem vessel elements and sieve tube elements?
23 Which row correctly identifies xylem vessel elements and sieve tube elements? xylem vessel element sieve tube element cytoplasm | nucleus | cytoplasm | nucleus Jv v x x key J/ = present 0 0N0 WwW > x J x x x x Jv Jv X = absent x x Jv x
Mark scheme: D
Q24 · The diagram shows a model which can be used to demonstrate mass flow
24 The diagram shows a model which can be used to demonstrate mass flow. tube T concentrated X Y dilute sucrose sucrose solution solution water rigid partially permeable containers X and Y are filled with sucrose solutions of different concentrations, causing water to move in or out of X and Y by osmosis or as a result of hydrostatic pressure. Sucrose solution then moves through tube T joining X and Y. Which description is correct? water potential in X direction of movement of compared with Y sucrose solution in tube T A less negative from X to Y B less negative from Y to X C more negative from X to Y D more negative from Y to X
Mark scheme: C
Q25 · Which of the following statements explain why a stem is both cut and connected to a…
25 Which of the following statements explain why a stem is both cut and connected to a potometer under water? 1 To prevent plasmolysis of xylem vessel elements 2 To prevent the collapse of xylem vessel elements 3 To prevent air entering xylem vessel elements A 1 only B 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: B
Q26 · What happens during ventricular systole in a mammalian heart?
26 What happens during ventricular systole in a mammalian heart? A aortic pressure increases B atrioventricular valves open C semilunar valves close D ventricular pressure decreases
Mark scheme: A
Q27 · Which two statements about the Bohr effect are correct?
27 Which two statements about the Bohr effect are correct? 1 Increasing the partial pressure of oxygen increases the percentage of oxyhaemoglobin. 2 Decreasing the partial pressure of carbon dioxide decreases the percentage of oxyhaemoglobin. 3 Increasing the partial pressure of carbon dioxide shifts the dissociation curve of haemoglobin to the left. 4 In low concentrations of carbon dioxide haemoglobin has a high affinity for oxygen. A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4
Mark scheme: B
Q28 · The diagram shows the heart and some of its blood vessels
28 The diagram shows the heart and some of its blood vessels. 2 3 4 1 Which combination of numbers correctly identifies the blood vessels that supply blood to the heart and carry blood from the heart? to the heart from the heart A 1 and 2 3 and 4 B 2 and 3 1 and 4 C 3 and 4 1 and 2 D 4 and 1 2 and 3
Mark scheme: D
Q29 · The diagram shows pressure changes in the left side of the heart during the cardiac cycle
29 The diagram shows pressure changes in the left side of the heart during the cardiac cycle. pressure key / kPa left ventricle aorta X left atrium 0 0 0.2 0.4 0.6 0.8 time / s What happens at X? A atrioventricular valves close B atrioventricular valves open C semilunar valves close D semilunar valves open
Mark scheme: A
Q30 · The photograph shows a type of blood cell
30 The photograph shows a type of blood cell. Which statements about these cells are correct? 1 Oxygen diffuses through the phospholipid bilayer. 2 Sodium ions diffuse through the phospholipid bilayer. 3 Water passes in and out of these cells by osmosis. A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: B
Q31 · Which symptom is specific to emphysema?
31 Which symptom is specific to emphysema? A excess mucus secretion by the goblet cells B inflammation of the bronchial epithelium C loss of elasticity of the alveolar walls D thickening of the smooth muscle of the bronchi
Mark scheme: C
Q32 · Haemoglobin can bind to carbon dioxide, carbon monoxide and oxygen
32 Haemoglobin can bind to carbon dioxide, carbon monoxide and oxygen. 1 carbon dioxide 2 carbon monoxide 3 oxygen Which gases share a binding site? A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: C
Q33 · Some studies suggest that smoking increases the risk of developing lung cancer
33 Some studies suggest that smoking increases the risk of developing lung cancer. The two graphs show the percentage of smokers and the deaths from lung cancer in men of two age groups between 1950 and 1998. 500 80 400 smokers / 60 deaths per 300 percentage 100 000 of 40 age group 200 of age group 20 100 0 0 1950 1960 1970 1980 1990 2000 1950 1960 1970 1980 1990 2000 year year key men aged 35 – 59 years men aged 60 – 74 years Which statement is not supported by the data in the graphs? A Deaths from lung cancer in men aged 35-59 years decreased by 50 % over the period of the study. B Deaths from lung cancer in men aged 60-74 years increased up to 1970. C The data for men aged 60-74 years between 1950 to 1970 suggests that lung cancer takes up to 20 years to develop. D The number of men aged 35-59 years who were smokers decreased by approximately 60 % over the period of the study.
Mark scheme: D
Q34 · Which row correctly matches a function with B-lymphocytes and T-lymphocytes?
34 Which row correctly matches a function with B-lymphocytes and T-lymphocytes? function B-lymphocytes T-lymphocytes 0 0O WwW > may become plasma cells may secrete antibodies provides a cell-mediated response provides a humoral response x x v v x v v x key JY true Xx false
Mark scheme: D
Q35 · What happens when people are injected with dead bacteria?
35 What happens when people are injected with dead bacteria? A B-lymphocytes produce antibodies. B B- lymphocytes produce antigens. C T- lymphocytes produce antibodies. D T- lymphocytes produce antigens.
Mark scheme: A
Q36 · Some children are born with Severe Combined Immune Deficiency (SCID)
36 Some children are born with Severe Combined Immune Deficiency (SCID). These children do not normally have any T-lymphocytes and suffer from many diseases. How may these children be cured? A bone marrow transplantation B continual use of antibiotics C transfusion of antibodies D vaccination against all diseases
Mark scheme: A
Q37 · Which of the following increase the risk of contracting TB?
37 Which of the following increase the risk of contracting TB? 1 drinking unpasteurised milk 2 eating shellfish which have fed on raw sewage 3 living in overcrowded conditions A 2 only B 1 and 2 C 1 and 3 D 2 and 3
Mark scheme: C
Q38 · Which box encloses a community?
38 Which box encloses a community? A sunlight B organisms C soil D weather
Mark scheme: B
Q39 · The diagram shows a simplified nitrogen cycle
39 The diagram shows a simplified nitrogen cycle. Which arrow represents the activity of nitrogen-fixing bacteria? nitrogen in atmosphere A plant animal proteins proteins D death and decay B ammonium compounds nitrites C nitrates
Mark scheme: A
Q40 · The diagram shows some values for gross primary productivity (GPP) and energy flow in an…
40 The diagram shows some values for gross primary productivity (GPP) and energy flow in an ecosystem, measured in kJ m–2 y–1. solar energy first trophic level 23 000 8000 second trophic level 10 500 third trophic level 4200 What percentage of GPP in the producers can be transferred to the tertiary consumers? A 1.3 % B 6.7 % C 18.3 % D 19.6 %
Mark scheme: A
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
5Biodiversity3Cells as the basic units of living organisms3Movement into and out of cells3Structure of nucleic acids and replication of DNA2Structure of transport tissues2The gas exchange system2The heart2The immune system2The microscope in cell studies2Transport mechanisms2Transport of oxygen and carbon dioxide2Antibodies and vaccination1Chromosome behaviour in mitosis1Factors that affect enzyme action1Fluid mosaic membranes1Infectious diseases1Mode of action of enzymes1Protein synthesis1Replication and division of nuclei and cells1Testing for biological molecules1The circulatory system1What you needed in this session
Cambridge’s own grade thresholds for 2012 Oct/Nov, Paper 1 · Variant 1. A higher threshold means an easier paper — the bar moves with how the cohort did.