Cambridge A Level Biology 9700 — 2011 May/June Paper 1 · Variant 2
9700/12/M/J/11 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper16 pages
















Mark scheme2 pages
Answers below. Sit the paper first if you are practising.


Questions as text
Q1 · Using a stage micrometer scale, one unit of an eyepiece graticule was calculated as 0.005…
1 Using a stage micrometer scale, one unit of an eyepiece graticule was calculated as 0.005 mm. The diameter of a spongy mesophyll cell was counted as 3.5 units on the eyepiece graticule. What is the estimate of the diameter of the cell? A 0.18 µm B 1.8 µm C 18.0 µm D 180 µm
Mark scheme: C
Q2 · Membranous sacs containing products of metabolism are formed by the endoplasmic reticulum…
2 Membranous sacs containing products of metabolism are formed by the endoplasmic reticulum in cells. Where are these products used? A inside and outside the cell B inside lysosomes only C inside the cell only D outside the cell only
Mark scheme: A
More questions on Cells as the basic units of living organisms
Q3 · Visking tubing is an artificial partially permeable membrane used to demonstrate diffusion
3 Visking tubing is an artificial partially permeable membrane used to demonstrate diffusion. Glucose molecules can pass through the pores in the membrane which are approximately 2.4 nm in diameter. Which of the following could pass through the pores? 1 bacteria 2 haemoglobin 3 ribosomes 4 glycogen A 2 only B 1 and 3 only C 2 and 4 only D none of these
Mark scheme: D
Q4 · Which of the structures are found in photosynthetic prokaryotes?
4 Which of the structures are found in photosynthetic prokaryotes? 1 cell surface membrane 2 cellulose wall 3 mesosomes 4 ribosomes 5 chloroplasts A 1, 2, 3 and 4 only B 1, 2, 4 and 5 only C 1, 3 and 4 only D 2, 3 and 5 only
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q5 · A human aorta has a lumen width of 2 cm
5 A human aorta has a lumen width of 2 cm. A human red blood cell has a diameter of 7 µm. How many red blood cells could be laid end to end across the diameter of the aorta lumen? A 2.9 × 10–3 B 2.9 × 10–2 C 2.9 × 102 D 2.9 × 103
Mark scheme: D
Q6 · Which polysaccharides are branched and which are unbranched?
6 Which polysaccharides are branched and which are unbranched? branched unbranched A amylose cellulose B amylopectin cellulose C cellulose amylose D cellulose amylopectin
Mark scheme: B
Q7 · Three carbohydrate molecules are shown
7 Three carbohydrate molecules are shown. CH2OH CH2OH CH2OH O O O OH OH OH OH OH CH2OH HO OH HO OH OH OH 1 2 3 Which two molecules combine to form a molecule of sucrose? A 1 and 2 B 1 and 3 C 2 and 3 D two of molecule 1
Mark scheme: B
Q8 · At which levels of protein structure do ionic bonds occur?
8 At which levels of protein structure do ionic bonds occur? 1 secondary 2 tertiary 3 quaternary A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3
Mark scheme: C
Q9 · Myoglobin is a protein with a similar function to haemoglobin
9 Myoglobin is a protein with a similar function to haemoglobin. However, myoglobin does not have a quaternary structure. Why does myoglobin not have a quaternary structure? A Myoglobin does not contain a haem group. B Myoglobin does not contain any alpha helices. C Myoglobin has a fibrous rather than a globular structure. D Myoglobin has only one polypeptide chain.
Mark scheme: D
Q10 · The diagram shows the structure of the amino acid cysteine
10 The diagram shows the structure of the amino acid cysteine. H H H N H S C C C OH H H O When two of these amino acids join together what bond(s) are formed? A disulfide bonds only B disulfide and peptide bonds C hydrogen, disulfide and peptide bonds D peptide bonds only
Mark scheme: D
Q11 · Which row describes a triglyceride?
11. Which row describes a triglyceride? A v Jv B v x Cc x J D x x key ¥ = correct X = incorrect
Mark scheme: D
Q12 · The graph shows the activation energy of an enzyme-catalysed reaction and the same…
12 The graph shows the activation energy of an enzyme-catalysed reaction and the same reaction without a catalyst. X energy Y reactants Z products reaction Which of the following shows the activation energy of the uncatalysed reaction? A X + Y – Z B X + Z – Y C X + Y D Y + Z
Mark scheme: C
Q13 · Which of the following statements are true of all enzymes?
13 Which of the following statements are true of all enzymes? 1 soluble in water 2 catalyse the breakdown of large molecules into smaller molecules 3 only have one active site 4 have a quaternary structure A 1, 2 and 3 only B 2, 3 and 4 only C 1 only D 4 only
Mark scheme: C
Q14 · The graphs show the effects of temperature and pH on enzyme activity
14 The graphs show the effects of temperature and pH on enzyme activity. Q R P rate of rate of reaction reaction S temperature pH Which statement explains the enzyme activity at the point shown? A At P, hydrogen bonds are formed between enzyme and substrate. B At Q, the kinetic energy of enzyme and substrate is highest. C At R, peptide bonds in the enzyme begin to break. D At S, the enzyme is completely denatured.
Mark scheme: A
Q15 · The diagram shows part of a cell surface membrane
15 The diagram shows part of a cell surface membrane. 3 4 5 2 1 Which molecules have both hydrophobic and hydrophilic regions? A 1 and 5 only B 1, 3 and 5 only C 1, 2, 4 and 5 only D 2, 3 and 4 only
Mark scheme: C
Q16 · Increasing which type of bond helps to increase the fluidity of the cell surface membrane?
16 Increasing which type of bond helps to increase the fluidity of the cell surface membrane? A C — O — C B C — N C C C D hydrogen
Mark scheme: C
Q17 · When cylinders of potato tissue were immersed in a 0.35 mol dm–3 sucrose solution, they…
17 When cylinders of potato tissue were immersed in a 0.35 mol dm–3 sucrose solution, they showed no change in mass. What will happen when cylinders are immersed in a 0.1 mol dm–3 sucrose solution? A The pressure potential of the cells will become more positive. B The solute potential of the cell will become more negative. C The water potential of the cells will become more negative. D The water potential of the solution will become less negative.
Mark scheme: A
Q18 · The graph represents the changes in the quantity of DNA present in one nucleus at…
18 The graph represents the changes in the quantity of DNA present in one nucleus at different stages in the life cycle of a mammal. X fertilisation 4 DNA content 3 / arbitrary units 2 egg 1 time Which stage takes place at X? A interphase B metaphase C prophase D telophase
Mark scheme: D
More questions on Replication and division of nuclei and cells
Q19 · At which stage of mitosis do these events occur?
19 At which stage of mitosis do these events occur? spiralisation and centromeres separate condensation of DNA A anaphase interphase B anaphase prophase C metaphase interphase D metaphase telophase
Mark scheme: B
Q20 · During which process does only mitosis occur?
20 During which process does only mitosis occur? A the production of antibodies from B-lymphocyte memory cells B the production of cancerous tissue in alveoli C the production of gametes D the production of root hairs
Mark scheme: B
More questions on Replication and division of nuclei and cells
Q21 · The table shows the tRNA anticodons for four amino acids
21 The table shows the tRNA anticodons for four amino acids. amino acid anticodon (tRNA) asparagine UUA glutamic acid CUU proline GGA threonine UGG A cell makes a polypeptide with the following amino acid sequence. glutamic acid – asparagine – threonine – proline What was the sequence of bases on the DNA from which this was formed? A GGAAATACCCTT B CAAAATACCCCT C CTTTTATGGGGA D CTTTTATCCGGA
Mark scheme: C
Q22 · What does the enzyme RNA polymerase synthesise?
22 What does the enzyme RNA polymerase synthesise? A a polypeptide from an mRNA template B a strand of DNA from an mRNA template C mRNA from a DNA template D mRNA from a tRNA template
Mark scheme: C
Q23 · The diagram shows part of a DNA molecule
23 The diagram shows part of a DNA molecule. A T G C C G C G How many hydrogen bonds are involved in holding these strands of DNA together? A 11 B 9 C 8 D 4
Mark scheme: A
More questions on Structure of nucleic acids and replication of DNA
Q24 · Which features enable the aorta to withstand high pressure at ventricular systole?
24 Which features enable the aorta to withstand high pressure at ventricular systole? A collagen fibres and elastin fibres B collagen fibres and endometrium C elastin fibres and large lumen D smooth muscle and small lumen
Mark scheme: A
Q25 · There is a decreased partial pressure of oxygen at high altitude compared to sea level
25 There is a decreased partial pressure of oxygen at high altitude compared to sea level. Which row is a correct description and reason for the response of the body to high altitude? description reason A more red blood cells because haemoglobin breaks down more rapidly B red blood cells have genes so red blood cells produce more switched on haemoglobin C oxygen dissociation curve shifts to compensate for an increase to the right in oxygen unloading in tissues D percentage saturation of haemoglobin so more red blood cells are produced with oxygen in lungs decreases to carry more haemoglobin
Mark scheme: D
Q26 · What events occur during contraction of the left ventricle?
26 What events occur during contraction of the left ventricle? A The bicuspid valve opens and semilunar valve in the aorta opens. B The bicuspid valve closes and semilunar valve in the aorta closes. C The pressure in the left atrium becomes greater than the pressure in the left ventricle. D The pressure in the left ventricle becomes greater than the pressure in the aorta.
Mark scheme: D
Q27 · Blood, tissue fluid and lymph each have a different composition
27 Blood, tissue fluid and lymph each have a different composition. Which row shows the composition of lymph? contains contains contains water antibodies lipid A v v v B v v x Cc v x v D x v v key / = present X = absent
Mark scheme: A
Q28 · Which processes are involved in transport in both phloem and xylem?
28 Which processes are involved in transport in both phloem and xylem? 1 diffusion 2 mass flow 3 osmosis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: A
Q29 · Which features of xerophytes are adaptations to reduce water loss by transpiration?
29 Which features of xerophytes are adaptations to reduce water loss by transpiration? rolled leaves fleshy leaves sunken stomata | thick waxy cuticles A Jv x x Jv B x Jv Jv Jv Cc Jv Jv Jv x D Jv Jv Jv Jv key J/ = reduces water loss X = no effect on water loss
Mark scheme: D
Q30 · The graph shows the results of measuring the concentration of sucrose in the xylem…
30 The graph shows the results of measuring the concentration of sucrose in the xylem, phloem and leaves of a plant during 24 hours. phloem sucrose concentration leaves xylem 06 00 12 00 18 00 00 00 time of day Which conclusion can be drawn from these results? A Osmosis moves water from the xylem to the phloem. B Sucrose is actively transported into the phloem from the leaves. C Sucrose is moved in both directions in the phloem. D Xylem tissue uses sucrose as a source of energy.
Mark scheme: B
Q31 · Water that is present inside a root hair cell may leave the cell and pass to the xylem
31 Water that is present inside a root hair cell may leave the cell and pass to the xylem. Through which pathway must the water travel? A apoplast B plasmodesmata C symplast D vacuoles
Mark scheme: C
Q32 · What are the approximate diameters of a trachea, an alveolus, a bronchiole and a bronchus?
32 What are the approximate diameters of a trachea, an alveolus, a bronchiole and a bronchus? trachea / mm alveolus / mm bronchiole / mm bronchus / mm A 18 0.25 0.50 12 B 18 0.50 0.25 12 C 12 0.25 0.50 18 D 12 0.50 0.25 18
Mark scheme: A
Q33 · What could occur as a result of inhaling the nicotine in tobacco smoke?
33 What could occur as a result of inhaling the nicotine in tobacco smoke? A cilia lining the respiratory tract are paralysed, causing an increase in the secretion of mucus from enlarged goblet cells B diffusion into blood capillaries followed by the release of adrenaline, which increases blood pressure and heart rate C diffusion into the epithelial cells of the respiratory tract, increasing the risk of mutation and acting as a potential carcinogen D dissolves in the lining of the alveoli, causing a breakdown in the alveolar walls and a decrease in surface area for gas exchange
Mark scheme: B
Q34 · Which effects does emphysema have?
34 Which effects does emphysema have? 1 surface area to volume ratio of lungs decreases 2 distance of the diffusion pathway increases 3 volume of oxygen diffused per unit time decreases A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only
Mark scheme: C
Q35 · Which of the diseases listed in the table are only treatable using antibiotics?
35 Which of the diseases listed in the table are only treatable using antibiotics? cholera | measles TB v v key JY = treatable X = not treatable 0 ONO DW > Ke 4K v x v v x v
Mark scheme: B
Q36 · The diagram shows properties of diseases
36 The diagram shows properties of diseases. Which area of the diagram shows the properties that are common to both cholera and tuberculosis? A bacterial infectious D C B transmitted by airborne droplets
Mark scheme: A
Q37 · The disease smallpox has been eradicated by a worldwide vaccination programme
37 The disease smallpox has been eradicated by a worldwide vaccination programme. Which set of reasons correctly identifies the problems associated with planning vaccination programmes to eradicate other diseases? sickle cell TB malaria cholera anaemia A invade gut cells genetically different poor response where immune inherited vaccines with system less recessive needed for malnourished effective condition active and children; dormant-to- boosters then active forms required B different stages poor response genetically different with different with inherited vaccines antigens; malnourished recessive needed for invades body children; condition active and cells boosters then dormant-to- required active forms C different different stages genetically invade gut cells vaccines with different inherited where immune needed for antigens; recessive system less active and invades body condition effective dormant-to- cells active forms D genetically different invade gut cells different stages inherited vaccines where immune with different recessive needed for system less antigens; condition active and effective invades body dormant-to- cells active forms
Mark scheme: C
Q38 · Anaerobic bacteria are abundant in waterlogged soils
38 Anaerobic bacteria are abundant in waterlogged soils. Which effect does this have on soil fertility and why? soil fertility reason A decreased bacteria convert nitrate to ammonia B decreased bacteria convert nitrate to nitrogen gas C increased bacteria cause decomposition D increased bacteria cause nitrogen fixation
Mark scheme: B
Q39 · What name is given to all the organisms in an area and their interactions with their…
39 What name is given to all the organisms in an area and their interactions with their environment? A community B ecosystem C habitat D niche
Mark scheme: B
Q40 · What is the function of nitrifying bacteria in the soil?
40 What is the function of nitrifying bacteria in the soil? A oxidation of ammonium compounds to nitrates B oxidation of nitrogen gas to nitrates C reduction of ammonium compounds to nitrates D reduction of nitrates to nitrites
Mark scheme: A
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
3Proteins3The gas exchange system3Transport mechanisms3Cells as the basic units of living organisms2Conservation2Fluid mosaic membranes2Mode of action of enzymes2Movement into and out of cells2Protein synthesis2Replication and division of nuclei and cells2The heart2The microscope in cell studies2Antibiotics1Antibodies and vaccination1Biodiversity1Chromosome behaviour in mitosis1Factors that affect enzyme action1Homeostasis in plants1Infectious diseases1Structure of nucleic acids and replication of DNA1The circulatory system1Transport of oxygen and carbon dioxide1What you needed in this session
Cambridge’s own grade thresholds for 2011 May/June, Paper 1 · Variant 2. A higher threshold means an easier paper — the bar moves with how the cohort did.