Cambridge A Level Biology 9700 — 2022 May/June Paper 1 · Variant 2

Question 1

1 The photomicrograph shows a bronchiole and alveoli. The magnification of the image is 360. What is the maximum diameter of the bronchiole lumen? A 14 m B 80 m C 140 m D 170 m

Accepted Answer

C

Question 2

2 A specimen is observed twice with a microscope, firstly using green light with a wavelength of 510 nm and then using red light with a wavelength of 650 nm. What happens to the magnification and resolution when using red light compared to green light? magnification resolution A decreases remains the same B increases increases C remains the same decreases D remains the same increases

Accepted Answer

C

Question 3

3 Four students were asked to match the function with the appearance of some cell structures in an animal cell. The functions were listed by number. 1 produces the mitotic spindle during cell division 2 synthesis of polypeptides 3 synthesis of lipids The appearances were listed by letter. V membranes which surround an enclosed inner cavity W non-membrane-bound, spherical structures X a double membrane interspersed with pores Y non-membrane-bound, cylindrical structures Z membrane-bound sacs, arranged as a flattened stack Which student correctly matched the numbered functions with the appearance of the cell structure? 1 2 3 A W X Z B W Z V C Y W V D Y Z W

Accepted Answer

C

Question 4

4 What is found in chloroplasts and mitochondria? A 70S ribosomes only B 70S ribosomes and circular DNA C 80S ribosomes and circular DNA D circular DNA only

Accepted Answer

B

Question 5

5 Which feature is correct for all known viruses? A capsid made of lipid and protein B DNA core C outer envelope of phospholipid D non-cellular structure

Accepted Answer

D

Question 6

6 Four extracts from different plant materials were made and tested with Benedict’s solution. The extracts were boiled with Benedict’s solution for 240 seconds and the final colour was recorded. colour produced extract after 240 seconds 1 red 2 yellow 3 blue 4 green Which sequence of plant extracts represents an increasing quantity of reducing sugar? A 1  2  4  3 B 3  1  2  4 C 3  2  1  4 D 3  4  2  1

Accepted Answer

D

Question 7

7 Which have properties that are dependent on hydrogen bonds? 1 cellulose 2 a molecule of haemoglobin 3 water A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 8

8 Which statement is correct? A Cellulose, glycogen and amylopectin are all polymers. B Ribose, amylase and phospholipid are all macromolecules. C Starch, glucose and amylose are all monomers. D Sucrose, deoxyribose and amylopectin are all polysaccharides.

Accepted Answer

A

Question 9

9 The diagram shows two amino acids. Some of the hydrogen atoms are numbered 1 to 6. H H O H H O N C C N C C H H OH H H OH 1 2 3 4 5 6 Which two numbered hydrogen atoms could contribute to the production of a molecule of water when a peptide bond forms between these two amino acids? A 1 and 4 B 1 and 6 C 3 and 5 D 2 and 4

Accepted Answer

B

Question 10

10

A student wrote four statements about water.

1

Water has a high specific heat capacity which maintains the temperature of water
within cells.

Mammals rely on water having a relatively low latent heat of vaporisation to keep
them cool.

When a negatively charged ion is added to water, the 5° charge on the hydrogen
atom is attracted to the ion.

When surrounded by water, non-polar molecules tend to be pushed apart from one
another.

Which statements are correct?

1 2 3 4
A Jv x Jv J key
B v x v Xx ¥ = correct
Cc x v x v X = not correct
D x Jv x x

Accepted Answer

B

Question 11

11 Typical enzymes are large globular proteins with a specific tertiary shape. Which molecular interactions are directly involved in maintaining the tertiary shape? 1 hydrogen bonding 2 disulfide bridges 3 hydrophobic interactions A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 12

12 Which statement about the Michaelis–Menten constant (Km) is correct for an enzyme with a low affinity for its substrate? A It has a high Km and reaches Vmax at a high substrate concentration. B It has a high Km and reaches Vmax at a low substrate concentration. C It has a low Km and reaches Vmax at a high substrate concentration. D It has a low Km and reaches Vmax at a low substrate concentration.

Accepted Answer

A

Question 13

13 Long chain, saturated fatty acids change from solid to liquid at higher temperatures compared with short chain, unsaturated fatty acids. Which fatty acids would be more likely to form triglycerides in mammals that live in cold climates? A long chain saturated B long chain unsaturated C short chain saturated D short chain unsaturated

Accepted Answer

D

Question 14

14 When animal cells are cultured, salt solution is added to keep the cells alive. What is the purpose of the salt solution? A to allow facilitated diffusion of salts into the cells B to prevent diffusion of other ions in or out of the cells C to prevent net movement of water into or out of the cells D to provide a source of energy for active transport

Accepted Answer

C

Question 15

15 The following are all processes that allow movement into cells. 1 phagocytosis 2 active transport 3 facilitated diffusion Which processes require ATP? A 1 and 2 B 2 and 3 C 1 only D 2 only

Accepted Answer

A

Question 16

16 Which features are required to allow for efficient diffusion? 1 a large surface area 2 a short diffusion pathway 3 maintenance of a constant diffusion gradient A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 17

17 What is a role of mitosis? A growth of organisms B production of genetically different cells C repair of cells D replacement of cancerous tissue

Accepted Answer

A

Question 18

18 Telomeres prevent the loss of genes from the ends of chromosomes during DNA replication, but they become shorter each time they are copied. In cancer cells and stem cells, the telomeres remain the same length. Which statement is correct for all human cells? A If telomeres become too short, a cell may stop dividing. B Adding telomeres could increase the rate of ageing of cells. C Telomeres are repaired by the enzyme RNA polymerase. D Telomeres prevent all damage occurring to DNA molecules.

Accepted Answer

A

Question 19

19 The nucleus of a mouse body cell in G1 phase of the cell cycle has 1.2  10–12 g of DNA. What will be the mass of DNA in the nucleus of the cell at the end of S phase and at the end of G2 phase of the cell cycle? end of S phase end of G2 phase A 1.2  10–12 g 1.2  10–12 g B 1.2  10–12 g 2.4  10–12 g C 2.4  10–12 g 1.2  10–12 g D 2.4  10–12 g 2.4  10–12 g

Accepted Answer

D

Question 20

20 What occurs during prophase in animal cells? 1 fragmentation of the nuclear envelope 2 nucleolus disappears 3 stained chromosomes become visible 4 centrioles replicate A 1, 2, 3 and 4 B 1, 2 and 3 only C 2 and 3 only D 1 and 4 only

Accepted Answer

B

Question 21

21 Which statement describes the structure of ATP? A It is a DNA nucleotide with two extra phosphates. B It is a DNA nucleotide with three extra phosphates. C It is an RNA nucleotide with two extra phosphates. D It is an RNA nucleotide with three extra phosphates.

Accepted Answer

C

Question 22

22 Rifampicin is an antibiotic used to treat tuberculosis. It works by inhibiting RNA polymerase in bacteria. Which processes are directly inhibited by this antibiotic? 1 DNA replication 2 enzyme synthesis 3 ATP synthesis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 only

Accepted Answer

D

Question 23

23 The table shows the DNA triplet codes for some amino acids. amino acid DNA triplet code amino acid DNA triplet code arginine GCA glycine CCA arginine GCC glycine CCG arginine GCG glycine CCT asparagine TTA lysine TTC asparagine TTG lysine TTT cysteine ACA proline GGA cysteine ACG proline GGC STOP ATC valine CAC The base sequence on the template DNA strand coding for part of a polypeptide is shown. CCA ACG GCG TTA TTC GCA Two mutations occur in this sequence during DNA replication. Which mutated template DNA strand would result in a shorter polypeptide? A CCA ACA GCA TTA TTC GCA B CCA ACG CCG TTA TTC GCC C CCA ACG GCG TTG ATC GCA D CCT ACG GCG TTA TTC GGA

Accepted Answer

C

Question 24

24 Some of the features present in transport tissues are listed. 1 lignified walls 2 cytoplasm 3 mitochondria 4 pits 5 plasmodesmata Which features are present in xylem vessel elements? A 1, 2, 3 and 4 B 1, 4 and 5 C 1 and 4 only D 2, 3 and 5

Accepted Answer

C

Question 25

25 The diagrams show transverse sections through parts of plants. 3 1 4 5 6 2 Which row is correct? transports contains lignin organic solutes A 1, 4, 5 2, 3, 6 B 1, 4, 6 2, 3, 5 C 2, 3, 5 1, 4, 6 D 2, 4, 6 1, 3, 5

Accepted Answer

B

Question 26

26 Which molecules form hydrogen bonds with water during transpiration? 1 cellulose in the xylem wall 2 suberin in the xylem wall 3 other water molecules in the xylem A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

C

Question 27

27 Some plant species can take up heavy metal contaminants that are dissolved in soil water and then transport them within the plant. Within plant cells, the heavy metals accumulate mainly in the vacuole. Which suggestions about the transport and accumulation of heavy metals are valid? 1 After initial entry into the root, some of the heavy metals can pass through the tonoplast to be stored in the vacuole of cells in the cortex. 2 The heavy metals take an apoplastic pathway in the xylem but at the endodermis must take a symplastic pathway. 3 The rate of accumulation of the heavy metals in leaf cells will be faster at night, when photosynthesis is not occurring, than during the day. 4 The presence of heavy metals causes the transpiration stream to slow down and reduce the rate of transpiration. A 1 and 2 B 1 and 4 C 2 and 3 D 3 and 4

Accepted Answer

A

Question 28

28 What is the correct route for the movement of water from cell to cell in the apoplast pathway? A through adjacent cell surface membranes B through intercellular spaces C through plasmodesmata D through the Casparian strip

Accepted Answer

B

Question 29

29 Which row shows the correct sequence for the movement of sucrose into phloem sieve tubes? first second third A diffusion of sucrose into the active transport of protons cotransport of protons and companion cell cytoplasm into the companion sucrose into the sieve tubes cell cytoplasm B cotransport of protons and active transport of protons diffusion of sucrose into sucrose into the companion out of the companion the sieve tubes cell cytoplasm cell cytoplasm C active transport of protons diffusion of sucrose into the cotransport of protons and into the companion companion cell cytoplasm sucrose into the sieve tubes cell cytoplasm D active transport of protons cotransport of protons and diffusion of sucrose into out of the companion sucrose into the companion the sieve tubes cell cytoplasm cell cytoplasm

Accepted Answer

D

Question 30

30 What occurs during ventricular systole in a mammalian heart? 1 Aortic pressure increases. 2 Atrial pressure does not change. 3 Ventricular pressure increases. A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

Accepted Answer

B

Question 31

31 Which plan diagram represents the tissues in a major vein? A B C D

Accepted Answer

D

Question 32

32 The diagram shows the pressure changes in various structures of the left side of the heart during the cardiac cycle. At the end of which period is the ventricle full of blood? A B C D pressure key / kPa left ventricle aorta left atrium 0 0.2 0.4 0.6 0.8 time / s

Accepted Answer

A

Question 33

33 Which description of movement of substances during tissue fluid formation is correct? A Low hydrostatic pressure forces substances out of the capillary at the arterial end allowing small substances to enter the fluid that bathes the cells. B Tissue fluid moves back into the venule due to a net hydrostatic pressure change in the capillary. C Movement of water in tissue fluid into the capillary by osmosis is due to the low water potential and low hydrostatic pressure inside the capillary. D A high water potential of the surrounding tissue fluid causes substances to leave the capillaries at the arterial end.

Accepted Answer

C

Question 34

34 Which row shows the change in concentration of some substances in red blood cells when carbon dioxide diffuses from active cells? carbonic hydrogencarbonate hydrogen anhydrase ions ions A decreases no change no change B increases increases increases C no change decreases increases D no change increases increases

Accepted Answer

D

Question 35

35 Which statements about the human gas exchange system are correct? 1 The absence of cartilage in small bronchioles allows them to expand. 2 The walls of the alveoli are made of cuboidal epithelium. 3 Alveoli secrete a substance which reduces surface tension. 4 The trachea and bronchi are supported by rings of cartilage. A 1 and 2 B 1 and 3 C 2 and 4 D 3 and 4

Accepted Answer

B

Question 36

36 Four types of cell in the gas exchange system are listed.

-— K Cc

alveolus epithelium cell
ciliated cell
goblet cell

smooth muscle cell

The ticks (Vv) in the table show specialised features of three of these types of cell.

many lots of . many Golgi
mitochondria oncoplasmic bodies
1 v
2 v
3 v v v

Which row correctly matches the specialised feature with the correct cell?

0 Oo WwW >

rr

-r— = eo ZL1/N
qe - = RKIlwo

Accepted Answer

C

Question 37

37 Why is it difficult to control the spread of tuberculosis? 1 Global air travel for commerce and tourism has increased. 2 The bacterium that causes tuberculosis has evolved resistance to some antibiotics. 3 The bacterium that causes tuberculosis shows great antigenic variability. 4 Civil unrest and poverty result in overcrowded living conditions. A 1, 2 and 4 B 1 and 4 only C 2 and 3 D 4 only

Accepted Answer

A

Question 38

38 Rabies is a viral disease which can be spread to humans by a bite from an infected animal. One method of treatment is to inject the patient with antibodies specific to the rabies virus. Which statements about this treatment are correct? 1 The patient will have natural passive immunity to rabies. 2 The injected antibodies will be broken down by the patient. 3 The patient’s memory cells will be able to produce this antibody more rapidly in the future. 4 The immunity provided will only last a short time. A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4

Accepted Answer

D

Question 39

39 A person’s blood group is determined by antigens present on the red blood cells. The table shows the antigens and antibodies in the blood of people with different blood groups. blood presence of A or B presence of antibodies to group antigens on red blood cells A or B in plasma A A only anti-B only B B only anti-A only AB A and B neither O neither anti-A and anti-B During a blood transfusion, it is essential that the person who receives the blood does not have antibodies to the donor’s blood. Which blood groups can be given to a person with blood group B? A A and B B AB and B C AB and O D B and O

Accepted Answer

D

Question 40

40 A student used a diagram to show four types of cells involved in the primary immune response. cell type 4 cell type 1 recognise the foreign release chemicals that antigen, move towards stimulate phagocytes it and surrounds it to engulf antigens unknown antigen enters the body cell type 3 cell type 2 produce the antibodies destroy cells infected required to bind to with viruses which would the antigen be released into the body Which row is correct? cell 1 cell 2 cell 3 cell 4 A B-lymphocyte macrophage T-killer cell T-helper cell B macrophage B-lymphocyte T-helper cell T-killer cell C T-helper cell T-killer cell B-lymphocyte macrophage D T-killer cell T-helper cell B-lymphocyte macrophage

Accepted Answer

C

Question paper16 pages

Mark scheme3 pages

Questions as text

Q1 · The photomicrograph shows a bronchiole and alveoli

Q2 · A specimen is observed twice with a microscope, firstly using green light with a…

Q3 · Four students were asked to match the function with the appearance of some cell…

Q4 · What is found in chloroplasts and mitochondria?

Q5 · Which feature is correct for all known viruses?

Q6 · Four extracts from different plant materials were made and tested with Benedict’s solution

Q7 · Which have properties that are dependent on hydrogen bonds?

Q8 · Which statement is correct?

Q9 · The diagram shows two amino acids

Q10 · A student wrote four statements about water

Q11 · Typical enzymes are large globular proteins with a specific tertiary shape

Q12 · Which statement about the Michaelis–Menten constant (Km) is correct for an enzyme with a…

Q13 · Long chain, saturated fatty acids change from solid to liquid at higher temperatures…

Q14 · When animal cells are cultured, salt solution is added to keep the cells alive

Q15 · The following are all processes that allow movement into cells

Q16 · Which features are required to allow for efficient diffusion?

Q17 · What is a role of mitosis?

Q18 · Telomeres prevent the loss of genes from the ends of chromosomes during DNA replication…

Q19 · The nucleus of a mouse body cell in G1 phase of the cell cycle has 1.2  10–12 g of DNA

Q20 · What occurs during prophase in animal cells?

Q21 · Which statement describes the structure of ATP?

Q22 · Rifampicin is an antibiotic used to treat tuberculosis

Q23 · The table shows the DNA triplet codes for some amino acids

Q24 · Some of the features present in transport tissues are listed

Q25 · The diagrams show transverse sections through parts of plants

Q26 · Which molecules form hydrogen bonds with water during transpiration?

Q27 · Some plant species can take up heavy metal contaminants that are dissolved in soil water…

Q28 · What is the correct route for the movement of water from cell to cell in the apoplast…

Q29 · Which row shows the correct sequence for the movement of sucrose into phloem sieve tubes?

Q30 · What occurs during ventricular systole in a mammalian heart?

Q31 · Which plan diagram represents the tissues in a major vein?

Q32 · The diagram shows the pressure changes in various structures of the left side of the…

Q33 · Which description of movement of substances during tissue fluid formation is correct?

Q34 · Which row shows the change in concentration of some substances in red blood cells when…

Q35 · Which statements about the human gas exchange system are correct?

Q36 · Four types of cell in the gas exchange system are listed

Q37 · Why is it difficult to control the spread of tuberculosis?

Q38 · Rabies is a viral disease which can be spread to humans by a bite from an infected animal

Q39 · A person’s blood group is determined by antigens present on the red blood cells

Q40 · A student used a diagram to show four types of cells involved in the primary immune…

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