Cambridge A Level Biology 9700 — 2021 Feb/March Paper 1 · Variant 2

Question 1

1 The photomicrograph shows onion cells. Y The actual length of the onion cell labelled Y is 350 m. What is the magnification of the photomicrograph? A 2.5 B 25 C 40 D 400

Accepted Answer

D

Question 2

2 Which row correctly shows the presence of a cell structure in typical plant cells and in typical
prokaryotic cells?

ole calls prokaryotic
cells
A | centrioles v x key
B | 70S ribosomes Jv v ¥ = present
C | lysosomes Jv v X = not present
D | cellulose cell walls v v

Accepted Answer

B

Question 3

3 Which letter identifies cell structures where semi-conservative replication of DNA occurs? chloroplasts B A mitochondria nuclei D C

Accepted Answer

A

Question 4

4 Which parts of a cell contain ribosomes? 1 chloroplast 2 mitochondrion 3 Golgi body 4 cytoplasm A 1, 2, 3 and 4 B 1, 2 and 3 only C 1, 2 and 4 only D 3 and 4 only

Accepted Answer

C

Question 5

5 Which range of cell diameters is typical for prokaryotic cells? A 1 nm to 5  102 nm B 1  103 nm to 5 m C 1  101 m to 5  102 m D 1  102 m to 5  103 m

Accepted Answer

B

Question 6

6 Which row shows a combination of molecules that could be found together in a single isolated

virus?
carbohydrate DNA phospholipid lipid protein RNA
A V J J J J J key
B J x Jv x x J / = present
Cc x v x x x v X = not present
D x Jv x x v x

Accepted Answer

D

Question 7

7 A student carried out four biochemical tests on a sample of food. test observation emulsion cloudy Benedict’s yellow biuret purple iodine yellow Which conclusion is supported by the results? A Fat is not present. B Glucose is present. C Protein is present. D Starch is present.

Accepted Answer

C

Question 8

8 Which diagram represents a molecule of -glucose? A B C D CH2OH CH2OH CH2OH CH2OH O O O OH HO O OH OH OH OH OH HO OH HO OH HO OH OH OH OH

Accepted Answer

A

Question 9

9 Which statements about glycosidic bonds are correct? 1 Condensation between glucose and fructose uses water and forms sucrose. 2 Glycogen contains -1,4 glycosidic bonds and -1,6 glycosidic bonds formed by condensation. 3 The hydrolysis of amylopectin uses water to break glycosidic bonds and release -glucose. 4 Amylose contains -1,6 glycosidic bonds formed by condensation. A 1, 2 and 3 B 1, 3 and 4 C 2 and 3 only D 2 and 4

Accepted Answer

C

Question 10

10 A triglyceride has ......1...... bonds formed by joining fatty acids to ......2...... . Which row correctly completes this sentence? 1 2 A ester glycine B hydrogen glycerol C ester glycerol D hydrogen glycine

Accepted Answer

C

Question 11

11 The diagram shows a phospholipid molecule divided into three regions, X, Y and Z. R, in region X, represents a range of possible chemical groups. X R O O P O – O CH2 CH CH2 O O C O C O CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 Y CH2 CH2 Z CH2 CH CH2 CH CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH2 CH3 CH3 Regions X, Y and Z affect the properties of cell surface membranes in different ways. Which row shows the effect of each region on the properties of a cell surface membrane? increases permeability of repels polar attracts water hydrophobic molecules molecules region A X X Y and Z B Y Y and Z X C Y and Z X Y and Z D Z Y and Z X

Accepted Answer

D

Question 12

12 Which statement about collagen is correct? A Tissues containing collagen fibres cannot stretch. B Each polypeptide chain forms an alpha helix. C Three helices are held together by hydrogen bonds. D Three polypeptide chains form a single collagen fibre.

Accepted Answer

C

Question 13

13 Catechol is a chemical found in a number of fruits. Catechol can be oxidised to a quinone by the enzyme catechol oxidase. Catechol oxidase is inhibited by parahydroxybenzoic acid (PHBA), which is structurally similar to catechol. In the presence of PHBA, the Michaelis-Menten constant (Km) for catechol oxidase increases. How does PHBA inhibit catechol oxidase? 1 PHBA and catechol can both bind to the enzyme but not at the same time. 2 PHBA is a non-competitive inhibitor of catechol oxidase. 3 PHBA decreases the Vmax of the reaction. A 1, 2 and 3 B 1 only C 2 only D 3 only

Accepted Answer

B

Question 14

14 Which statements about the fluid mosaic model of a membrane are correct? 1 The movement of phospholipids in the membrane is reduced if the fatty acid tails are saturated. 2 Glycoproteins in the outer layer of the membrane can move. 3 Channel proteins are fixed in position. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

B

Question 15

15 Diagram 1 and diagram 2 show how the transverse section through a leaf changes when the leaf is moved from solution X to solution Y. leaf solution X solution Y diagram 1 diagram 2 Which row describes the water potential of the leaf cells and surrounding solutions in diagram 2 compared with diagram 1? water potential of leaf cells water potential of solution Y in diagram 2 compared with compared with water water potential of leaf cells potential of solution X in diagram 1 A less negative less negative B less negative more negative C more negative less negative D more negative more negative

Accepted Answer

A

Question 16

16 Which features must always be present for water to move between two solutions by osmosis? 1 carrier proteins 2 cell surface membrane 3 selectively permeable membrane 4 water potential gradient A 1, 2 and 3 B 1, 3 and 4 C 2 and 4 D 3 and 4 only

Accepted Answer

D

Question 17

17 When living pancreatic cells were placed in a solution of a red stain called neutral red, the cytoplasm became red. The cells were then removed from the solution of neutral red. The red stain in the cytoplasm moved into vesicles, which were exported from the cell, eventually leaving the cell colourless. Which transport mechanisms could explain how the red stain entered and left the cells? A active transport and facilitated diffusion B diffusion and exocytosis C facilitated diffusion and endocytosis D osmosis and exocytosis

Accepted Answer

B

Question 18

18 DNA molecules in a eukaryotic cell must be packaged compactly because their combined length is much greater than the diameter of the nucleus. Which structures are required during the process of packaging DNA molecules compactly? A chromatids B chromosomes C histone proteins D telomeres

Accepted Answer

C

Question 19

19 Which statements about mitosis are correct? 1 Mitosis results in genetically identical cells. 2 Mitosis is involved in asexual reproduction. 3 Mitosis occurs immediately after cytokinesis. 4 Mitosis can be used to repair damaged cells. A 1, 2, 3 and 4 B 1, 2 and 4 only C 1 and 2 only D 3 and 4 only

Accepted Answer

C

Question 20

20 A human chromosome is made up of different parts. Some parts of a typical human chromosome are more numerous than others. Which parts are listed in order from least numerous to most numerous in a human white blood cell? A centromere  chromatid  histone protein B DNA molecule  telomere  centromere C histone protein  telomere  DNA molecule D telomere  centromere  chromatid

Accepted Answer

A

Question 21

21 A piece of double-stranded DNA containing 12  103 nucleotides is transcribed and translated to produce a single polypeptide. What is the maximum number of amino acids in this polypeptide? A 6  103 B 4  103 C 2  103 D 1  103

Accepted Answer

C

Question 22

22 Which statements about complementary base pairing are correct? 1 Cytosine forms two hydrogen bonds with guanine. 2 Purines and pyrimidines are different sizes. 3 Adenine forms the same number of hydrogen bonds with thymine as it does with uracil. 4 The base pairs in a molecule of DNA are of equal length and equal width. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4

Accepted Answer

D

Question 23

23 What are the products when a DNA molecule replicates? A two molecules of DNA each made of a sequence of paired bases B two molecules of DNA each made of a sequence of paired nucleotides C two strands of DNA each made of a sequence of paired bases D two strands of DNA each made of a sequence of paired nucleotides

Accepted Answer

B

Question 24

24 Which descriptions apply to phloem sieve tube elements and to xylem vessel elements? 1 no cytoplasm 2 no end walls 3 no nucleus A 1, 2 and 3 B 1 and 3 only C 2 only D 3 only

Accepted Answer

D

Question 25

25 Some of the parts of a plant root involved in water transport are listed. 1 Casparian strip 2 cell walls of cortex cells 3 endodermal cells 4 epidermal cells 5 xylem vessels Which sequence shows part of a pathway through which water can move across a root? A 2  3  5 B 2  1  5 C 4  2  1 D 4  3  2

Accepted Answer

A

Question 26

26 What is an example of a mass flow system in a plant? A the loading of amino acids from the surrounding tissues into companion cells B the movement of sap through the phloem sieve tubes in the stem C the movement of water across the root along the symplastic pathway D the movement of water vapour from the internal spaces in the leaf out through the stomata

Accepted Answer

B

Question 27

27 The diameter of a tree trunk usually decreases slightly during the day. Which changes in environmental factors during the day could cause the diameter to decrease even more? increased temperature C A D increased light increased B intensity humidity

Accepted Answer

A

Question 28

28 Which statement about the role of co-transporter proteins in the movement of sucrose is correct? A Co-transporter proteins pump hydrogen ions into phloem sieve tubes along with sucrose. B Hydrogen ions diffuse through co-transporter proteins with sucrose into companion cells. C Plasmodesmata move sucrose into phloem sieve tubes via co-transporter proteins. D Sucrose is moved through co-transporter proteins by active transport.

Accepted Answer

B

Question 29

29 Which row correctly describes the heart during atrial systole? wall of atrioventricular semilunar ventricle valve valve A contracted closed closed B contracted open open C relaxed closed open D relaxed open closed

Accepted Answer

D

Question 30

30 The diagram shows a capillary, some tissue cells and a lymph vessel. 2 capillary 1 3 tissue cells 4 lymph vessel Which row correctly identifies arrows 1, 2, 3 and 4? 1 2 3 4 A diffusion of glucose flow of water and diffusion of flow of tissue fluid small solutes carbon dioxide B diffusion of glucose flow of water and osmosis of water diffusion of oxygen plasma proteins C diffusion of oxygen flow of water and diffusion of flow of tissue fluid small solutes carbon dioxide D diffusion of oxygen flow of water and osmosis of water diffusion of plasma proteins carbon dioxide

Accepted Answer

C

Question 31

31 The table shows the results used to draw an oxygen dissociation curve for adult haemoglobin. partial pressure of oxygen 1 2 3 4 5 6 7 / kPa volume of oxygen per gram of haemoglobin / cm3 g–1 0.11 0.32 0.58 0.77 0.96 1.07 1.15 What is the percentage increase in the volume of oxygen per gram of haemoglobin when the partial pressure of oxygen increases from 3 kPa to 5 kPa? A 32.8% B 39.6% C 60.4% D 65.5%

Accepted Answer

D

Question 32

32 The graph shows the oxygen dissociation curves for adult haemoglobin at two carbon dioxide concentrations. 100 P Q percentage saturation of haemoglobin with oxygen S R 0 0 partial pressure of oxygen / kPa Which letters show measurements taken in the capillaries of the lungs and in the capillaries of active muscle? lungs active muscle A P R B P S C Q R D Q S

Accepted Answer

A

Question 33

33 Which substances can combine with adult haemoglobin and reduce the oxygen-carrying capacity of the blood? 1 carbon dioxide 2 carbon monoxide 3 hydrogencarbonate ions 4 hydrogen ions A 1, 2, 3 and 4 B 1, 2 and 4 only C 1 and 3 only D 2 and 4 only

Accepted Answer

B

Question 34

34 How many times must a molecule of carbon monoxide pass through a cell surface membrane as it diffuses from an air space in an alveolus, through a cell in the capillary wall, into a red blood cell? A 3 B 4 C 5 D 6

Accepted Answer

C

Question 35

35 The heart rate of a person at rest was recorded at intervals over two 15-minute periods. During the first five minutes of the second 15-minute period, the person smoked a cigarette. The graph shows the results recorded during the two 15-minute periods. 110 smoking for first five 100 minutes 90 heart rate / beats per min 80 not smoking 70 60 0 5 10 15 time / mins What can be concluded from the graph? A Carbon monoxide affects the heart rate. B Carbon monoxide binds to haemoglobin increasing the flow of blood. C Nicotine increases the heart rate so is a stimulant. D The heart rate increases as a result of smoking.

Accepted Answer

D

Question 36

36 Emphysema is a type of chronic obstructive pulmonary disease (COPD). A person with emphysema has difficulties in breathing out. Why does emphysema cause difficulties in breathing out? A Smooth muscle fibres in the airways are destroyed. B Too little mucus is produced in the bronchi. C The elasticity of the alveoli decreases. D The surface area of the alveoli becomes larger.

Accepted Answer

C

Question 37

37 Which factors contribute to outbreaks of measles after natural disasters? 1 contamination of drinking water with untreated sewage 2 lack of effective vaccination coverage in the population before the disaster 3 people living in overcrowded accommodation A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

D

Question 38

38 There are two main classes of antibiotics, broad spectrum and narrow spectrum. Broad spectrum antibiotics affect a wide range of bacteria, while narrow spectrum antibiotics affect specific types of bacteria. Which uses of antibiotics may result in antibiotic-resistant bacteria? 1 a broad spectrum antibiotic given to reduce the effects of the influenza virus 2 a broad spectrum antibiotic to treat Mycobacterium tuberculosis in humans 3 a narrow spectrum antibiotic to treat diarrhoea and sickness in cattle A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 39

39 People with the autoimmune disease myasthenia gravis can have a treatment to relieve the symptoms. In this treatment, one of the components of their blood is removed. Which blood component is removed? A antibodies B macrophages C neutrophils D red blood cells

Accepted Answer

A

Question 40

40 Why are spleen cells fused with myeloma cells during monoclonal antibody production? A so that the antibodies become specific for the necessary antigen B so that the resulting hybridoma cells can reproduce indefinitely C to allow antibodies that are not specific for the required antigen to be removed D to increase the rate of production of antibodies produced by the hybridoma cells

Accepted Answer

B

Question paper16 pages

Mark scheme3 pages

Questions as text

Q1 · The photomicrograph shows onion cells

Q2 · Which row correctly shows the presence of a cell structure in typical plant cells and in…

Q3 · Which letter identifies cell structures where semi-conservative replication of DNA occurs?

Q4 · Which parts of a cell contain ribosomes?

Q5 · Which range of cell diameters is typical for prokaryotic cells?

Q6 · Which row shows a combination of molecules that could be found together in a single…

Q7 · A student carried out four biochemical tests on a sample of food

Q8 · Which diagram represents a molecule of -glucose?

Q9 · Which statements about glycosidic bonds are correct?

Q10 · A triglyceride has ......1.....

Q11 · The diagram shows a phospholipid molecule divided into three regions, X, Y and Z

Q12 · Which statement about collagen is correct?

Q13 · Catechol is a chemical found in a number of fruits

Q14 · Which statements about the fluid mosaic model of a membrane are correct?

Q15 · Diagram 1 and diagram 2 show how the transverse section through a leaf changes when the…

Q16 · Which features must always be present for water to move between two solutions by osmosis?

Q17 · When living pancreatic cells were placed in a solution of a red stain called neutral red…

Q18 · DNA molecules in a eukaryotic cell must be packaged compactly because their combined…

Q19 · Which statements about mitosis are correct?

Q20 · A human chromosome is made up of different parts

Q21 · A piece of double-stranded DNA containing 12  103 nucleotides is transcribed and…

Q22 · Which statements about complementary base pairing are correct?

Q23 · What are the products when a DNA molecule replicates?

Q24 · Which descriptions apply to phloem sieve tube elements and to xylem vessel elements?

Q25 · Some of the parts of a plant root involved in water transport are listed

Q26 · What is an example of a mass flow system in a plant?

Q27 · The diameter of a tree trunk usually decreases slightly during the day

Q28 · Which statement about the role of co-transporter proteins in the movement of sucrose is…

Q29 · Which row correctly describes the heart during atrial systole?

Q30 · The diagram shows a capillary, some tissue cells and a lymph vessel

Q31 · The table shows the results used to draw an oxygen dissociation curve for adult…

Q32 · The graph shows the oxygen dissociation curves for adult haemoglobin at two carbon…

Q33 · Which substances can combine with adult haemoglobin and reduce the oxygen-carrying…

Q34 · How many times must a molecule of carbon monoxide pass through a cell surface membrane as…

Q35 · The heart rate of a person at rest was recorded at intervals over two 15-minute periods

Q36 · Emphysema is a type of chronic obstructive pulmonary disease (COPD)

Q37 · Which factors contribute to outbreaks of measles after natural disasters?

Q38 · There are two main classes of antibiotics, broad spectrum and narrow spectrum

Q39 · People with the autoimmune disease myasthenia gravis can have a treatment to relieve the…

Q40 · Why are spleen cells fused with myeloma cells during monoclonal antibody production?

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