Cambridge A Level Biology 9700 — 2020 Oct/Nov Paper 1 · Variant 1

Question 1

1 Which row shows the correct order of size of these cell structures? 1 width of a mitochondrion 2 width of a ribosome 3 width of a cell surface membrane 4 width of a chloroplast largest  smallest A 1 4 2 3 B 1 4 3 2 C 4 1 2 3 D 4 2 1 3

Accepted Answer

C

Question 2

2 The diagram shows a stage micrometer scale viewed through an eyepiece containing a graticule. The small divisions of the stage micrometer scale are 0.1 mm. 0 10 20 30 40 50 60 70 80 90 100 The stage micrometer scale is replaced by a slide of a plant cell. 0 10 20 30 40 50 60 70 80 90 100 What is the actual length of the nucleus in the plant cell? A 8 m B 25 m C 200 m D 0.8 mm

Accepted Answer

B

Question 3

3 Insulin is a hormone synthesised from two polypeptide chains inside cells of the pancreas.

Which row shows the cell structures that are used in producing insulin and releasing it from the

cells?
rough
Golgi body lysosome endoplasmic
reticulum
A v v x
B v v v
Cc v x v
D x v v

key
JY = used

X = not used

Accepted Answer

C

Question 4

4 The electron micrograph shows a cell structure in a eukaryotic cell. Which statements about this cell structure are correct? 1 ATP is synthesised in this cell structure. 2 The cell structure is made of protein molecules. 3 The cell structure replicates during interphase of the cell cycle. A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

Accepted Answer

C

Question 5

5 Four students were asked to match the function with the appearance of some cell structures in an animal cell. The functions were listed by number. 1 synthesis of polypeptides 2 synthesis of lipids 3 packaging of hydrolytic enzymes that will remain in the cell The appearances were listed by letter. V membranes which surround an enclosed inner cavity W non-membrane-bound, spherical structures X a double membrane interspersed with pores Y non-membrane-bound, cylindrical structures Z membrane-bound sacs, arranged as a flattened stack Which student correctly matched the numbered function with the appearance of the cell structure? 1 2 3 A W V Z B W Z Y C Z W Z D Z V W

Accepted Answer

A

Question 6

6 The DNA of typical prokaryotes is naked and circular. Which statement describes how the DNA of eukaryotes differs from the DNA of typical prokaryotes? A Only DNA of eukaryotes has a nuclear envelope around it and is a double helix. B Only DNA of eukaryotes has a nuclear envelope around it and is circular. C Only DNA of eukaryotes has proteins attached to it and is a double helix. D Only DNA of eukaryotes has proteins attached to it and is linear.

Accepted Answer

D

Question 7

7 A student carried out the Benedict’s test on two different types of milk, X and Y. A sample of each type of milk was heated to 100 C in a water-bath with Benedict’s solution and the time taken for the first appearance of a colour change was recorded. The results are shown in the table. time for first appearance type of of a colour change with milk Benedict’s solution / s X 13 Y 26 Which row shows the biological molecule the student detected in each sample of milk and the sample of milk with the highest concentration of this biological molecule? biological sample of milk with the molecule present in highest concentration of each sample of milk this biological molecule A glucose X B glucose Y C reducing sugar X D reducing sugar Y

Accepted Answer

C

Question 8

8 The diagram shows the structure of a monomer. CH2OH O H H H OH H HO OH H OH Which molecules contain this monomer? amylopectin A C B glycogen D sucrose

Accepted Answer

B

Question 9

9 Which molecules are formed by condensation which involves a carboxyl group? A amylopectin, collagen, triglyceride, sucrose B amylopectin, collagen, triglyceride C amylopectin, -globin, sucrose D collagen, -globin, triglyceride

Accepted Answer

D

Question 10

10 Which row correctly matches the function with the structural features of cellulose, collagen,
glycogen or triglyceride?

structure

molecules held
molecule function fibrous together by branched chains
hydrogen bonds

A cellulose support Jv Jv x
triglyceride | energy source x x x

B collagen strengthening Jv Jv x
cellulose support Jv x v

Cc collagen strengthening Jv Jv Jv
glycogen storage x x Jv

D glycogen storage x Jv Jv
x Jv x

triglyceride energy source

key J/=correct X = not correct

Accepted Answer

A

Question 11

11 The diagram shows the amino acids in a polypeptide. key type of amino acid polar basic polar acidic Asp Arg Lys polar Cys Thr Lys Leu non-polar Pro Asn Arg Val Ser Asn Glu Lys Thr Arg Phe Met Lys Phe Gln Met Ala His Val Gln Met Ala His Asn Asp Ala Glu Cys Thr Ser C terminal end Tyr Ser Glu Asn Lys Ser Thr Ser Ser N terminal end Ser Ala Ala An enzyme catalyses the hydrolysis of any peptide bond between a non-polar amino acid and any polar amino acid. How many small peptides and single amino acids will be formed by the action of this enzyme? small single peptides amino acids A 6 1 B 8 1 C 12 3 D 13 4

Accepted Answer

D

Question 12

12 Which properties of water reduce temperature changes inside cells? 1 cohesion 2 latent heat of vaporisation 3 specific heat capacity A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

Accepted Answer

D

Question 13

13 Which enzyme is extracellular? A Amylase in saliva is an enzyme that catalyses the breakdown of starch in the mouth. B ATP synthetase is an enzyme found in mitochondria that synthesises ATP. C DNA polymerase is an enzyme that helps build DNA molecules by assembling nucleotides. D RNA polymerase is an enzyme involved in the process of gene transcription.

Accepted Answer

A

Question 14

14 The graph shows how the concentration of components of an enzyme-catalysed reaction changes with time. Which line represents enzymes with empty active sites? A concentration B C D time

Accepted Answer

B

Question 15

15 Which effects can non-competitive inhibitors have on enzyme-controlled reactions? 1 lower the Km value 2 reduce the concentration of the product 3 reduce the rate of a metabolic pathway A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

D

Question 16

16 Which processes can allow transport into or out of a cell? 1 active transport 2 facilitated diffusion 3 osmosis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 17

17 Plant cells were put into one of three different concentrations of sugar solution, 10%, 5% and 2.5%. The cells were left for 50 minutes and then observed using a light microscope. cell X cell Y cell Z vacuole Which statements are correct? 1 Cell Y had a lower water potential than the sugar solution it was put into. 2 Cell Z was put into the 10% sugar solution. 3 Cell Z had a less negative water potential than the sugar solution it was put into. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 18

18 During telophase of mitosis, a scientist stains the chromosomes of a diploid animal cell with a fluorescent dye to observe the telomeres. This cell has 22 chromosomes. How many telomeres will the scientist observe in one of the nuclei? A 22 B 44 C 66 D 88

Accepted Answer

B

Question 19

19 Methotrexate is a drug used to treat cancer. It can act as an enzyme inhibitor preventing the synthesis of nucleotides containing thymine. Cells treated with methotrexate are not able to complete the cell cycle. A cell entering telophase is treated with methotrexate. Which stage of the cell cycle will be affected by the action of methotrexate? A anaphase B interphase C metaphase D prophase

Accepted Answer

B

Question 20

20 Which stage of mitosis is correctly described? A In anaphase chromosomes line up across the equator. B In metaphase the centrosomes replicate. C In prophase chromatids move to opposite poles. D In telophase chromosomes uncoil to form chromatin.

Accepted Answer

D

Question 21

21 The diagram represents a nucleotide containing cytosine. base Which statements about this nucleotide are correct? 1 The carbohydrate could be ribose. 2 The organic base contains nitrogen. 3 Base pairing occurs with guanine. 4 Cytosine is a purine. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4

Accepted Answer

A

Question 22

22 A section of DNA contains 73 base pairs. number of bases on each strand adenine cytosine guanine thymine strand 1 29 V 14 W strand 2 21 X Y Z Which row represents the correct number of bases? V W X Y Z A 9 21 14 9 29 B 14 29 9 9 21 C 21 9 29 9 14 D 29 9 29 14 9

Accepted Answer

A

Question 23

23 The photograph shows a section of a stem. Which labelled part is the xylem? B A C D

Accepted Answer

C

Question 24

24 Some fungi cause wilting in crop plants by growing within the xylem vessel elements. Which process will be directly affected by these fungi? A cohesion between water molecules B development of root pressure C mass flow during movement of assimilates D uptake of water by root hair cells

Accepted Answer

A

Question 25

25 Which features have a role in the transport of water in xylem vessel elements? 1 capillary action 2 adhesion 3 hydrogen bonding A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 26

26 The loading of sucrose into companion cells involves a number of processes. Which process is active? A the movement of hydrogen ions into the cytoplasm of companion cells B the movement of hydrogen ions out of the cytoplasm of companion cells C the movement of sucrose into companion cells D the movement of sucrose out of companion cells

Accepted Answer

B

Question 27

27 The statements describe events that occur during the movement of sucrose. 1 Hydrostatic pressure is decreased. 2 Hydrostatic pressure is increased. 3 Sucrose is loaded into the phloem vessel. 4 Sucrose is unloaded from the phloem vessel. 5 Water moves by osmosis into the phloem. 6 Water moves by osmosis out of the phloem. 7 Water potential decreases in the phloem. 8 Water potential increases in the phloem. Which sequence correctly describes what happens in a plant at a source during the movement of sucrose? A 3  7  5  2 B 3  8  6  1 C 4  7  5  2 D 4  8  6  1

Accepted Answer

A

Question 28

28 Which are present in the walls of capillaries?

0 0O WwW D>

endothelium

~ «QOS

smooth
muscle

\ \ x

elastic tissue

\ « & x

collagen
fibres

x \ \ x

key
/ = present

X = not present

Accepted Answer

A

Question 29

29 The photomicrograph shows three white blood cells labelled X, Y and Z. Y X Z Which row correctly identifies these cells? cell X cell Y cell Z A lymphocyte monocyte neutrophil B lymphocyte neutrophil monocyte C monocyte neutrophil lymphocyte D neutrophil monocyte lymphocyte

Accepted Answer

C

Question 30

30 Which sequence of letters correctly identifies the order of events during the cardiac cycle? T atrial walls contract U impulse is delayed a fraction of a second V wave of excitation enters the atrioventricular node W wave of excitation passes down the Purkyne tissue X wave of excitation spreads from the sinoatrial node Y ventricles contract A B C D V W X X T U V U Y T Y V X W T Y W U W T Y X V U

Accepted Answer

A

Question 31

31 The graph shows the effect of three different partial pressures of carbon dioxide on the oxygen dissociation curve for human haemoglobin. 100 X partial pressure of Y carbon dioxide percentage Z saturation of X = 3.0 kPa haemoglobin with oxygen Y = 5.0 kPa Z = 7.0 kPa 0 0 12 partial pressure of oxygen / kPa What effect does decreasing the partial pressure of carbon dioxide have on haemoglobin? A It is less efficient at taking up oxygen and less efficient at releasing oxygen. B It is less efficient at taking up oxygen and more efficient at releasing oxygen. C It is more efficient at taking up oxygen and less efficient at releasing oxygen. D It is more efficient at taking up oxygen and more efficient at releasing oxygen.

Accepted Answer

C

Question 32

32 What is correct about the transport of carbon dioxide by blood? 1 The enzyme carbonic anhydrase catalyses the formation of carbonic acid in red blood cells. 2 Carbon dioxide diffuses from active cells to red blood cells and reacts with water. 3 Carbonic acid dissociates forming hydrogen ions that combine with haemoglobin to form carbaminohaemoglobin. A 1, 2 and 3 B 1 and 2 only C 2 and 3 only D 3 only

Accepted Answer

B

Question 33

33 Which statements about all bronchioles are correct? 1 they have goblet cells 2 they have ciliated cells 3 they have muscle tissue A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

D

Question 34

34 The graph shows the volume of air breathed out quickly and with force, following a deep breath in, for three different people, X, Y and Z. 5 X 4 Y volume of 3 air breathed out / dm3 2 Z 1 0 0 1 2 3 4 5 time / s What is a possible explanation for the differences in the volume of air breathed out by these people shown? chronic bronchitis emphysema normal lung function A X Z Y B Y X Z C Y Z X D Z Y X

Accepted Answer

C

Question 35

35 The diagrams show some of the pathogens that cause disease in humans and some of the ways they are transmitted. 1 2 W bacterium protoctist contaminated water pathogens method of transmission 3 Y X Morbillivirus contaminated coughs and food sneezes What is the correct pathogen and method of transmission for the disease TB? A 1 and W B 1 and X C 2 and X D 3 and Y

Accepted Answer

B

Question 36

36 The proportion of the local population who have malaria in area R is higher than the proportion in area S. Which factor causes this difference? A Area R has a more humid climate than area S. B Area R is nearer the equator than area S. C There is a higher population in area R than area S. D There is less sewage treatment in area R than area S.

Accepted Answer

A

Question 37

37 Species X is a single-celled eukaryote. Species X has been genetically modified to produce penicillin, which does not harm the cell walls of species X. What may be concluded from this information? 1 The cell walls of species X are chemically different from those of bacteria. 2 The cell walls of species X are made of peptidoglycan. 3 The cell walls of species X are made of cellulose. A 1 and 2 B 1 only C 2 only D 3 only

Accepted Answer

B

Question 38

38 When exposed to an antigen for a second time, memory cells stimulate a secondary immune response. Which correctly shows the secondary immune response? memory cell A B C D secretes divides into divides into secretes antibodies plasma cells plasma cells and antibodies and memory cells divides into memory cells

Accepted Answer

C

Question 39

39 Monoclonal antibodies are produced for use in diagnosis or treatment of disease. To obtain the antibodies for an antigen, a mouse is injected with the antigen. Some of the events in the production of the monoclonal antibody are listed. 1 Plasma cells are fused with cancer cells to form a hybridoma. 2 Hybridomas that secrete the required antibody are identified and cloned. 3 B-lymphocytes that recognise the antigen multiply and become plasma cells. 4 Hybridomas divide by mitosis and secrete antibodies. 5 Plasma cells are removed from the mouse spleen. What is the sequence of the first four events in the production of the monoclonal antibody? A 3  5  1  2 B 3  5  1  4 C 5  1  2  4 D 5  1  4  2

Accepted Answer

B

Question 40

40 Which row describes passive immunity?

involves an

memory

triggered by permanent
: immune cells ;
an antigen protection
response produced

A v v v v
B v v x Xx
Cc x x v v
D x x x Xx

key
Y = correct

X = not correct

Accepted Answer

D

Question paper20 pages

Mark scheme3 pages

Questions as text

Q1 · Which row shows the correct order of size of these cell structures?

Q2 · The diagram shows a stage micrometer scale viewed through an eyepiece containing a…

Q3 · Insulin is a hormone synthesised from two polypeptide chains inside cells of the pancreas

Q4 · The electron micrograph shows a cell structure in a eukaryotic cell

Q5 · Four students were asked to match the function with the appearance of some cell…

Q6 · The DNA of typical prokaryotes is naked and circular

Q7 · A student carried out the Benedict’s test on two different types of milk, X and Y

Q8 · The diagram shows the structure of a monomer

Q9 · Which molecules are formed by condensation which involves a carboxyl group?

Q10 · Which row correctly matches the function with the structural features of cellulose…

Q11 · The diagram shows the amino acids in a polypeptide

Q12 · Which properties of water reduce temperature changes inside cells?

Q13 · Which enzyme is extracellular?

Q14 · The graph shows how the concentration of components of an enzyme-catalysed reaction…

Q15 · Which effects can non-competitive inhibitors have on enzyme-controlled reactions?

Q16 · Which processes can allow transport into or out of a cell?

Q17 · Plant cells were put into one of three different concentrations of sugar solution, 10%…

Q18 · During telophase of mitosis, a scientist stains the chromosomes of a diploid animal cell…

Q19 · Methotrexate is a drug used to treat cancer

Q20 · Which stage of mitosis is correctly described?

Q21 · The diagram represents a nucleotide containing cytosine

Q22 · A section of DNA contains 73 base pairs

Q23 · The photograph shows a section of a stem

Q24 · Some fungi cause wilting in crop plants by growing within the xylem vessel elements

Q25 · Which features have a role in the transport of water in xylem vessel elements?

Q26 · The loading of sucrose into companion cells involves a number of processes

Q27 · The statements describe events that occur during the movement of sucrose

Q28 · Which are present in the walls of capillaries?

Q29 · The photomicrograph shows three white blood cells labelled X, Y and Z

Q30 · Which sequence of letters correctly identifies the order of events during the cardiac…

Q31 · The graph shows the effect of three different partial pressures of carbon dioxide on the…

Q32 · What is correct about the transport of carbon dioxide by blood?

Q33 · Which statements about all bronchioles are correct?

Q34 · The graph shows the volume of air breathed out quickly and with force, following a deep…

Q35 · The diagrams show some of the pathogens that cause disease in humans and some of the ways…

Q36 · The proportion of the local population who have malaria in area R is higher than the…

Q37 · Species X is a single-celled eukaryote

Q38 · When exposed to an antigen for a second time, memory cells stimulate a secondary immune…

Q39 · Monoclonal antibodies are produced for use in diagnosis or treatment of disease

Q40 · Which row describes passive immunity?

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