Cambridge A Level Biology 9700 — 2019 Feb/March Paper 1 · Variant 2

Question 1

1 The diagram below was drawn from an electron micrograph of an animal cell. Which diagram would represent the same cell seen under a simple light microscope, using daylight as the only light source? A B C D

Accepted Answer

A

Question 2

2 The diameter of a red blood cell in a diagram was measured as 2.5 cm. The actual diameter of the red blood cell was 7 µm. Which calculation would give the correct magnification for the red blood cell in the diagram? 7 2500 25 000 25 000 A B C D 25 000 7 7 7000

Accepted Answer

C

Question 3

3 The diagram shows a fin whale drawn to scale. 3 m A student made three statements about the diagram. 1 The magnification is ×0.006. 2 The ratio of actual size to diagram size is 1667 : 1. 3 The fin whale has an actual length of 24 m. Which statements are correct? A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 3 only

Accepted Answer

C

Question 4

4 Which structures are found in both chloroplasts and mitochondria? 1 70S ribosomes 2 80S ribosomes 3 circular DNA A 1 and 3 B 2 and 3 C 1 only D 3 only

Accepted Answer

A

Question 5

5 Radioactively labelled amino acids are introduced into a cell that is actively secreting an enzyme. In which cell structure will the radioactivity first become concentrated? A B C D

Accepted Answer

A

Question 6

6 Ribosomes exist as separate subunits that are bound together during protein synthesis. What do these subunits consist of? A mRNA and protein B mRNA and tRNA C rRNA and protein D rRNA and tRNA

Accepted Answer

C

Question 7

7 Four solutions were tested with Benedict’s solution. The table shows the colour of the solutions after testing. solution colour 1 green 2 blue 3 brick red 4 yellow Which row shows solutions that could have given these results? solution 1 solution 2 solution 3 solution 4 A 0.05% reducing 0.5% non-reducing 1.0% reducing 0.1% reducing sugar sugar sugar sugar B 0.5% reducing 0.0% reducing 1.0% reducing 0.1% reducing sugar sugar sugar sugar C 1.0% reducing 1.0% non-reducing 1.5% reducing 0.5% reducing sugar sugar sugar sugar D 0.05% non-reducing 0.5% reducing 1.0% non-reducing 0.1% non-reducing sugar sugar sugar sugar

Accepted Answer

A

Question 8

8 The diagram shows a molecule of three hexose sugars. CH2OH CH2OH CH2OH O C O C O H H H OH OH H H C C C C C C OH H OH H H OH HO OH HO H H CH2OH C C C C C C H OH H OH OH H 1 2 3 Which row correctly shows examples of carbohydrates in which these three hexose sugars occur? sucrose cellulose amylopectin A 1 2 3 B 1 3 2 C 2 3 1 D 3 2 1

Accepted Answer

D

Question 9

9 Which feature of glycogen distinguishes glycogen from starch? A All glycogen molecules are highly branched. B  All glycogen molecules are polysaccharides. C All glycogen molecules contain α-glucose. D All glycogen molecules contain 1,4-glycosidic bonds.

Accepted Answer

A

Question 10

10 A student wrote four statements about what happens during hydrolysis of a carbohydrate. 1 Disaccharides are formed from monosaccharides. 2 Glycosidic bonds are broken. 3 Molecules of water are released. 4 Monosaccharides can be formed. Which statements are correct? A 1 and 2 B 1 and 3 C 2 and 4 D 3 and 4

Accepted Answer

C

Question 11

11 The table compares three molecules, X, Y and Z, which contain the elements carbon, hydrogen and oxygen only. The percentage of carbon, hydrogen and oxygen atoms in each molecule is shown. molecule % carbon % hydrogen % oxygen X 25.0 50.0 25.0 Y 28.5 47.7 23.8 Z 34.6 61.6 3.8 Which row correctly identifies molecules X, Y and Z? molecule X Y Z A monosaccharide disaccharide polysaccharide B monosaccharide polysaccharide triglyceride C polysaccharide triglyceride monosaccharide D triglyceride monosaccharide polysaccharide

Accepted Answer

B

Question 12

12 Which statements about the differences between phospholipids and triglycerides are correct? 1 Phospholipids have hydrophobic regions but triglycerides do not. 2 The fatty acids in a phospholipid are always saturated but in a triglyceride they may be saturated or unsaturated. 3 Phospholipids are polar molecules but triglycerides are non-polar. A 1 and 2 B 1 only C 2 and 3 D 3 only

Accepted Answer

D

Question 13

13 An investigation was carried out into the effect of different treatments on the permeability of the cell surface membranes and tonoplasts of beetroot cells. Beetroot cell vacuoles contain a red pigment. This pigment is unable to pass out of the cells because it cannot diffuse through the tonoplasts or cell surface membranes. 1 cm3 cubes were cut from beetroot tissue and washed in running water for 20 minutes to remove any pigment released from damaged cells. The cubes were then placed in test-tubes with different contents and observed for five minutes. Which row shows a correct explanation for the observation recorded for one of the treatments? treatment observation explanation A dilute contents of membrane proteins hydrochloric acid test-tube stay clear have been denatured B ethanol contents of lipids, including membrane test-tube turn red phospholipids, have dissolved C water at 20 °C contents of membrane proteins test-tube stay clear have been denatured D water at 80 °C contents of lipids, including membrane test-tube turn red phospholipids, have dissolved

Accepted Answer

B

Question 14

14 Which levels of protein structure can determine the specificity of an enzyme? 1 primary 2 secondary 3 tertiary 4 quaternary A 1, 2, 3 and 4 B 1, 2 and 3 only C 1, 2 and 4 only D 3 and 4 only

Accepted Answer

A

Question 15

15 The graph shows the effect of substrate concentration on the initial rate of an enzyme-catalysed reaction. The enzyme concentration is constant. S T initial rate of reaction R 0 0 substrate concentration Which statement about the graph is correct? A Between R and S the number of enzyme molecules is limiting the rate of reaction. B Between R and S the number of product molecules is limiting the rate of reaction. C Between S and T the number of enzyme molecules is limiting the rate of reaction. D Between S and T the number of substrate molecules is limiting the rate of reaction.

Accepted Answer

C

Question 16

16 The diagram represents the reversible interaction between the active site of an enzyme and different inhibitors, X and Y. change in the shape enzyme molecules of the active site of the enzyme molecule active site active site inhibitor X inhibitor Y Which row correctly identifies the type of inhibition shown by inhibitor X and inhibitor Y? X Y A competitive competitive B competitive non-competitive C non-competitive competitive D non-competitive non-competitive

Accepted Answer

B

Question 17

17 Which statements about the movement of water in and out of cells are correct? 1 Water moves from regions of more negative water potential to regions of less negative water potential. 2 Water can cross cell membranes by passing through channel proteins. 3 Water can pass through cellulose cell walls. A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

D

Question 18

18 The diagram shows part of a cell surface membrane. 1 6 2 3 4 5 Which row correctly identifies functions of two of the numbered molecules? molecule function molecule function A 1 acts as an antigen 4 stabilises the membrane B 2 acts as a receptor 5 active transport C 3 facilitated diffusion 4 regulates the fluidity of the membrane D 6 active transport 5 acts as an enzyme

Accepted Answer

A

Question 19

19 During mitosis in animal cells, which process occurs after prophase? A Centrioles move towards the poles of the cell. B Centromeres attach to spindle microtubules. C Chromatids join to form chromosomes. D Chromosomes condense and become visible.

Accepted Answer

B

Question 20

20 Embryonic stem cells are able to replicate continuously. What happens to the telomeres during repeated mitotic cell cycles of embryonic stem cells? A Their lengths increase. B Their lengths decrease. C They are completely lost. D They stay the same length.

Accepted Answer

D

Question 21

21 A length of DNA was analysed and sequenced. 24% of its nitrogenous bases were adenine. Which percentage of the bases will be cytosine? A 24 B 26 C 48 D 76

Accepted Answer

B

Question 22

22 Rifampicin is an antibiotic used to treat tuberculosis (TB). It works by inhibiting RNA polymerase in bacteria. Which processes are directly inhibited by this antibiotic? 1 DNA replication 2 transcription 3 ATP synthesis A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 only

Accepted Answer

D

Question 23

23 Which terms describe the method by which water is transported within xylem vessel elements? 1 mass flow 2 cohesion-tension 3 osmosis A 1 and 2 B 1 and 3 C 2 only D 3 only

Accepted Answer

A

Question 24

24 Which combination of features is characteristic of a phloem sieve tube element as it is loaded from a source? water potential of the lignification of the cell wall phloem sieve tube element A less negative than source absent B less negative than source present C more negative than source absent D more negative than source present

Accepted Answer

C

Question 25

25 The diagrams show transverse sections of parts of a plant with some transport tissues labelled from 1 to 6. leaf stem root 3 1 4 5 6 2 Which row shows tissues that mainly transport water and tissues that mainly transport sucrose? mainly transport mainly transport water sucrose A 1 and 3 4 and 6 B 1 and 6 3 and 5 C 2 and 3 4 and 5 D 3 and 5 2 and 6

Accepted Answer

B

Question 26

26 Which properties of lignin are important for the function of xylem vessels in the stem of a tall plant, such as a tree? 1 It is inflexible so does not bend easily. 2 It is not permeable to water. 3 It is strong to resist collapse under pressure. 4 It has weaker adhesion to water molecules than cellulose. A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and 4

Accepted Answer

A

Question 27

27 A heating sleeve was placed around the trunk of a small tree at a height of 1m above the ground.
This allowed a narrow region of the tree trunk to be heated to 60°C.

How will heating this region to 60°C affect the transport of phloem sap and xylem sap between

the roots and leaves?

movement of

phloem sap xylem sap
A J Jv
B Jv x
Cc x v
D x x

key
/ = transport continues

X = transport stops

Accepted Answer

C

Question 28

28 The photomicrograph shows a section through a structure found in mammals viewed using a light microscope. W ×60 What are the main components of layer W? A collagen fibres only B elastic fibres and collagen fibres C smooth muscle and elastic fibres D squamous epithelial cells forming an endothelium

Accepted Answer

C

Question 29

29 Which row correctly identifies the locations in which a type of molecule or cell can be present?

type of molecule or cell blood lymph tsue
A antigens v x x key
B glucose v x Jv Y= can be present
Cc lymphocyte x v Jv X = cannot be present
D neutrophil Jv Jv v

Accepted Answer

D

Question 30

30 Which statements about the formation of haemoglobinic acid are correct? 1 It is linked to the action of carbonic anhydrase. 2 It prevents blood from becoming too acidic by removing excess hydrogen ions. 3 It can only occur when oxygen associates with haemoglobin. A 1, 2 and 3 B 1 and 2 only C 1 only D 2 and 3 only

Accepted Answer

B

Question 31

31 The graph shows the oxygen dissociation curves of haemoglobin for eight species of mammal. 100 key mammals in decreasing order percentage 1 23456 7 8 of size oxygen 50 1   elephant saturation of 2   horse haemoglobin 3   human 4   sheep 5   fox 6   cat 0 7   rat 0 2 4 6 8 10 12 14 8   mouse partial pressure of oxygen / kPa Which conclusion is consistent with the data shown in the graph? A The haemoglobin of larger mammals will combine with oxygen at a lower partial pressure of oxygen than that of smaller mammals. B The haemoglobin of larger mammals will release oxygen at a higher partial pressure of oxygen than that of smaller mammals. C The metabolic activity of the mammal is directly proportional to the ability of its haemoglobin to release oxygen. D The size of the mammal is directly proportional to the ability of its haemoglobin to release oxygen.

Accepted Answer

A

Question 32

32 The statements list some of the events in the cardiac cycle. They are not in the correct order. 1 The impulse travels through Purkyne tissue. 2 The ventricles contract. 3 The atrioventricular node delays the impulse for a fraction of a second. 4 The muscle tissue of the sinoatrial node contracts. 5 The wave of excitation sweeps upwards from the base of the ventricles. 6 A wave of excitation sweeps across the atria. 7 The atria contract. Which statement describes the second of these events to occur in the cardiac cycle? A 1 B 4 C 6 D 7

Accepted Answer

C

Question 33

33 Which statement about typical bronchioles is correct? A They have cartilage and ciliated cells. B They have goblet cells and smooth muscle. C They have smooth muscle and cartilage. D They have smooth muscle and ciliated cells.

Accepted Answer

D

Question 34

34 Tobacco smoke contains substances that affect the functioning of the human body. substance effect w nicotine 1 decreases oxygenation of haemoglobin x carbon monoxide 2 increases risk of cancer y tar 3 increases risk of blood clotting What shows the substances matched with their correct effects? A w-1, x-2, y-3 B w-1, x-3, y-2 C w-2, x-1, y-3 D w-3, x-1, y-2

Accepted Answer

D

Question 35

35 Which two diseases are transmitted by airborne droplets? A cholera and malaria B malaria and measles C measles and tuberculosis (TB) D tuberculosis (TB) and cholera

Accepted Answer

C

Question 36

36 Which features do the causative agents of measles, malaria and tuberculosis (TB) have in

common?
cytoplasm sroduce ATP sntigons
A v v x key
B v x v v = have in common
Cc x v x X = do not have in common
D x x Jv

Accepted Answer

D

Question 37

37 What explains why most viruses that cause diseases in humans are unaffected by antibiotics? A Viral antigens do not bind to antibiotics. B Viral nucleic acids are protected by a protein coat. C Viruses contain no ribosomes or mRNA. D Viruses reproduce inside living eukaryotic cells.

Accepted Answer

D

Question 38

38 Why does the white blood cell count increase in people with leukaemia? A More antibodies are required so there are more B-lymphocytes. B More lymphocytes are produced in bone marrow. C More memory cells are produced in plasma. D More T-lymphocytes are required to stimulate the immune system.

Accepted Answer

B

Question 39

39 Where are antibodies found during an immune response?

on the surface
of pathogens

~ Kw &

on the surface
of memory cells

x < x

key
JY = antibodies found

X = antibodies not found

Accepted Answer

B

Question 40

40 The graph shows the changes that occur in the concentration of antibodies in the blood of a baby before birth and during the first few months after birth. birth total antibodies concentration of antibodies antibodies in blood of made by baby baby antibodies from mother 0 2 4 6 8 10 12 14 16 time / months Which description about the changes in immunity during the first few months after birth is correct? A active artificial immunity decreases, active natural immunity increases B active natural immunity decreases, active artificial immunity increases C passive artificial immunity decreases, active natural immunity increases D passive natural immunity decreases, active natural immunity increases

Accepted Answer

D

Question paper16 pages

Mark scheme3 pages

Questions as text

Q1 · The diagram below was drawn from an electron micrograph of an animal cell

Q2 · The diameter of a red blood cell in a diagram was measured as 2.5 cm

Q3 · The diagram shows a fin whale drawn to scale

Q4 · Which structures are found in both chloroplasts and mitochondria?

Q5 · Radioactively labelled amino acids are introduced into a cell that is actively secreting…

Q6 · Ribosomes exist as separate subunits that are bound together during protein synthesis

Q7 · Four solutions were tested with Benedict’s solution

Q8 · The diagram shows a molecule of three hexose sugars

Q9 · Which feature of glycogen distinguishes glycogen from starch?

Q10 · A student wrote four statements about what happens during hydrolysis of a carbohydrate

Q11 · The table compares three molecules, X, Y and Z, which contain the elements carbon…

Q12 · Which statements about the differences between phospholipids and triglycerides are…

Q13 · An investigation was carried out into the effect of different treatments on the…

Q14 · Which levels of protein structure can determine the specificity of an enzyme?

Q15 · The graph shows the effect of substrate concentration on the initial rate of an…

Q16 · The diagram represents the reversible interaction between the active site of an enzyme…

Q17 · Which statements about the movement of water in and out of cells are correct?

Q18 · The diagram shows part of a cell surface membrane

Q19 · During mitosis in animal cells, which process occurs after prophase?

Q20 · Embryonic stem cells are able to replicate continuously

Q21 · A length of DNA was analysed and sequenced

Q22 · Rifampicin is an antibiotic used to treat tuberculosis (TB)

Q23 · Which terms describe the method by which water is transported within xylem vessel…

Q24 · Which combination of features is characteristic of a phloem sieve tube element as it is…

Q25 · The diagrams show transverse sections of parts of a plant with some transport tissues…

Q26 · Which properties of lignin are important for the function of xylem vessels in the stem of…

Q27 · A heating sleeve was placed around the trunk of a small tree at a height of 1m above the…

Q28 · The photomicrograph shows a section through a structure found in mammals viewed using a…

Q29 · Which row correctly identifies the locations in which a type of molecule or cell can be…

Q30 · Which statements about the formation of haemoglobinic acid are correct?

Q31 · The graph shows the oxygen dissociation curves of haemoglobin for eight species of mammal

Q32 · The statements list some of the events in the cardiac cycle

Q33 · Which statement about typical bronchioles is correct?

Q34 · Tobacco smoke contains substances that affect the functioning of the human body

Q35 · Which two diseases are transmitted by airborne droplets?

Q36 · Which features do the causative agents of measles, malaria and tuberculosis (TB) have in…

Q37 · What explains why most viruses that cause diseases in humans are unaffected by…

Q38 · Why does the white blood cell count increase in people with leukaemia?

Q39 · Where are antibodies found during an immune response?

Q40 · The graph shows the changes that occur in the concentration of antibodies in the blood of…

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