Cambridge A Level Biology 9700 — 2014 Oct/Nov Paper 1 · Variant 1

Question 1

1 When making measurements in experiments, which methods could have parallax errors? 1 using a calibrated eyepiece graticule to measure length 2 using a measuring cylinder to measure volume 3 using a ruler to measure length of a shoot A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

Accepted Answer

C

Question 2

2 Which part of the cell is often continuous with the rough endoplasmic reticulum? A cell surface membrane B Golgi apparatus C mitochondrion D nuclear envelope

Accepted Answer

D

Question 3

3 Which structures are found in both chloroplasts and mitochondria? 1 70S ribsomes 2 80S ribsomes 3 circular DNA A 1 and 3 B 2 and 3 C 1 only D 3 only

Accepted Answer

A

Question 4

4 Tay-Sachs disease occurs when cells are unable to produce an enzyme, leading to a build up of certain lipids in cells. Which cell structure would not function correctly, resulting in the disease? A Golgi apparatus B lysosome C mitochondrion D smooth endoplasmic reticulum

Accepted Answer

B

Question 5

5 Which structures are present in a cell of Plasmodium? Golgi ribosomes apparatus B A C D mitochondria

Accepted Answer

A

Question 6

6 The diagram shows a triglyceride molecule that has been partially hydrolysed. H H C OH H C OH O H H H H H H H H H H C O C C C C C C C C C H C H C H H H H H H H H H C H H C H H C H H C H H C H H C H C H H H What will be the products of the total hydrolysis of the molecule shown? A a molecule of glycerol and a saturated fatty acid molecule only B a molecule of glycerol and an unsaturated fatty acid molecule only C a molecule of water, a molecule of glycerol and a saturated fatty acid molecule D a molecule of water, a molecule of glycerol and an unsaturated fatty acid molecule

Accepted Answer

B

Question 7

7 Which shows α-glucose? A B CH2OH CH2OH H C O OH H C O H H H C C C C OH H OH H HO C C H HO C C OH H OH H OH C D H CH2OH H C O CH2OH HO C O OH H H C C C C H H OH H HO C C OH H C C H OH OH H OH

Accepted Answer

B

Question 8

8 Which correctly matches the functional and structural features of cellulose, collagen, glycogen or
triglyceride?

structure

molecule held
function fibrous together by branched chains
hydrogen bonds

A cellulose support J Jv x
triglyceride | energy source x x x

B collagen strengthening Jv Jv x
cellulose support v x J

Cc collagen strengthening Jv Jv Jv
glycogen storage x x v

D glycogen storage x Jv Jv
triglyceride | energy source x Jv x

key /=true xX = false

Accepted Answer

A

Question 9

9 The diagram shows the relationship between the levels of protein structure and bonds. 1 2 3 4 5 Which row is correct? 1 2 3 4 5 A primary peptide secondary ionic tertiary B secondary hydrogen tertiary peptide primary C tertiary ionic primary peptide quaternary D quaternary ionic tertiary ionic secondary

Accepted Answer

D

Question 10

10 How many molecules of oxygen are bound to one molecule of haemoglobin, when it is fully saturated with oxygen? A 1 B 2 C 4 D 8

Accepted Answer

C

Question 11

11 Why do large increases in the temperature or pH alter enzyme activity? 1 They change the three-dimensional shape of the enzyme. 2 They disrupt hydrogen and ionic bonds in the enzyme. 3 They increase hydrophobic interactions in the enzyme. A 1 and 2 B 1 and 3 C 2 and 3 D 1 only

Accepted Answer

A

Question 12

12 Ethylene glycol is a chemical used to prevent water from freezing. If ethylene glycol is swallowed accidentally, it is metabolised by an enzyme found in liver cells to produce a toxic product. The enzyme normally catalyses the oxidation of ethanol to a harmless product. People who have swallowed ethylene glycol are treated with large doses of ethanol. This prevents formation of a toxic product and allows the body to excrete the ethylene glycol. Which statement describes why this treatment works? A Ethanol binds near the active site on the enzyme, altering its shape. B Ethanol binds permanently to the active site of the enzyme, blocking it. C Ethanol changes the tertiary structure of the enzyme, denaturing it. D Ethanol is more likely to bind to the active site on the enzyme.

Accepted Answer

D

Question 13

13 Increasing which type of bond helps to increase the fluidity of the cell surface membrane? A C — O — C B C — N C C C D hydrogen

Accepted Answer

C

Question 14

14 The diagram shows three routes, X, Y and Z, through which substances can pass across a cell surface membrane. X Y Z Which correctly shows the routes for vitamin D, which is fat soluble, and vitamin C, which is water soluble? vitamin D vitamin C A Y X B X Y C X Z D Z Y

Accepted Answer

C

Question 15

15 In plants adapted to cold conditions, their cell surface membranes change as the weather gets colder, allowing the plants to carry out exocytosis. Which change occurs in their cell surface membranes? A a decrease in the ratio of proteins to saturated phospholipids B a decrease in the ratio of unsaturated phospholipids to saturated phospholipids C an increase in the ratio of proteins to unsaturated phospholipids D an increase in the ratio of unsaturated phospholipids to saturated phospholipids

Accepted Answer

D

Question 16

16 Which statement about a diploid cell is not correct? A It can undergo a mitotic division to allow growth to occur. B It can undergo a mitotic division to repair a cell. C It can undergo a reduction division to form haploid cells. D It is one that possesses two complete sets of chromosomes.

Accepted Answer

B

Question 17

17 Laboratory mice whose p53 genes had been switched off developed tumours. When their p53 genes were switched on again, the tumour cells stopped dividing and died within a few days. Healthy cells in the mice were unaffected. What do these observations suggest? A p53 protein speeds up the mitotic cell cycle B p53 protein causes all cells to die C the p53 gene acts as a tumour suppressor gene D the p53 gene encourages the growth of tumours

Accepted Answer

C

Question 18

18 The diagram shows part of a DNA molecule. 2 3 1 4 Which regions contain phosphate groups? A 1 and 2 B 1 and 4 C 3 and 4 only D 2, 3 and 4

Accepted Answer

C

Question 19

19 Some antibiotics work by binding to ribosomes and preventing protein synthesis. Which statement explains why these antibiotics kill bacterial cells but not human cells? A In bacterial cells mRNA is formed in the cytoplasm from naked DNA. B Ribosomes in human cells have a different structure from those in bacterial cells. C The antibiotics cannot pass through human cell surface membranes. D The tRNA molecules in bacterial cells are different from those in human cells.

Accepted Answer

B

Question 20

20 Which statements about tRNA are correct? 1 contains base pairing 2 contains hydrogen bonds 3 is single stranded A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

A

Question 21

21 What is the main function of a companion cell in phloem tissue? A providing cytoplasmic contact with the sieve tube element for loading B providing structural support for the sieve tube element C providing the nucleus for cell division in the phloem D providing the source of assimilates for storage

Accepted Answer

A

Question 22

22 How does sucrose move from chloroplasts to the phloem? 1 mass flow 2 apoplast pathway 3 symplast pathway A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

D

Question 23

23 A large number of aphids were used to collect samples of the contents of the sieve tube elements of a tomato plant. sieve tube element sample taken micropipette tomato plant stem (aphid and stem are not drawn to the same scale) Different samples of the sieve tube solution were tested. Which was the correct result? Benedict’s test iodine solution before hydrolysis after hydrolysis A blue blue blue - black B blue red orange C red blue blue - black D red red orange

Accepted Answer

B

Question 24

24 Which row is correct for the pulmonary vein? blood carried muscle in walls lumen size A deoxygenated thick small B deoxygenated thin large C oxygenated thick small D oxygenated thin large

Accepted Answer

D

Question 25

25 Which statement describes the Bohr effect? A In high partial pressure of oxygen and high partial pressure of carbon dioxide, the affinity of haemoglobin for oxygen increases. B In high partial pressure of oxygen and low partial pressure of carbon dioxide, the affinity of haemoglobin for oxygen decreases. C In low partial pressure of oxygen and high partial pressure of carbon dioxide, the affinity of haemoglobin for oxygen decreases. D In low partial pressure of oxygen and low partial pressure of carbon dioxide, the affinity of haemoglobin for oxygen is unchanged.

Accepted Answer

C

Question 26

26 What is produced by the action of carbonic anhydrase? A carbaminohaemoglobin B haemoglobinic acid C hydrogencarbonate ions D oxyhaemoglobin

Accepted Answer

C

Question 27

27 During the cardiac cycle, the movement of the valves causes sounds that can be heard using a stethoscope. What causes the first sound after atrial systole in the cardiac cycle? 1 closing of the atrioventricular valves 2 opening of the semilunar valves 3 closing of the semilunar valves A 1 and 2 B 1 and 3 C 1 only D 3 only

Accepted Answer

C

Question 28

28 The following are all parts of the heart that control the heart action. 1 sinoatrial node (SAN) 2 atrioventricular node (AVN) 3 Purkyne tissue Which row for atrial contraction and ventricular contraction is correct? atrial contraction ventricular contraction AVN produces wave of SAN produces wave of A excitation excitation B Purkyne tissue carries AVN produces wave of wave of excitation excitation C SAN and AVN node Purkyne tissue carries the produce wave of excitation wave of excitation D SAN produces wave of Purkyne tissue carries wave excitation of excitation

Accepted Answer

D

Question 29

29 The photomicrograph shows a cross-section through a bronchus. X Y What is the function of the tissues X and Y? X Y A secrete mucus prevent collapse of the airway B support the airway dilate airway C trap dust and dirt secrete mucus D waft dust and dirt upwards constrict airway

Accepted Answer

D

Question 30

30 Which component(s) of tobacco smoke cause an increase in blood pressure and clot formation? 1 carcinogens 2 nicotine 3 tar A 1, 2 and 3 B 1 and 3 only C 2 and 3 only D 2 only

Accepted Answer

D

Question 31

31 Peak Flow is used in hospitals to diagnose some lung diseases. It measures the maximum rate at which air can be breathed out from the lungs. How will the Peak Flow for a person with emphysema differ from that for a healthy person? A It falls as carbon monoxide reduces oxygen-carrying capacity of the blood. B It falls as elastic fibres are damaged in the alveoli. C It remains constant as the damage to the lungs does not affect the lung volume. D It rises as larger air spaces make it easier for the air to flow.

Accepted Answer

B

Question 32

32 The following are all methods of transmission of infectious diseases. 1 droplet 2 food 3 contact 4 vector Which row shows the correct organism and method of transmission of each disease? malaria TB HIV A bacterium virus virus 4 1 and 2 3 and 4 B protoctist bacterium virus 4 1 and 2 3 C protoctist virus bacterium 3 1 3 D bacterium protoctist bacterium 3 1 1 and 3

Accepted Answer

B

Question 33

33 40% of the world’s population live in an area where malaria is a threat to health. In recent years there have been many more cases of malaria in Africa. What is the social factor that is letting the spread of malaria get out of control? A an increase in drug resistant forms of malaria B climate change C difficulty in producing a vaccine D migration of people because of wars

Accepted Answer

D

Question 34

34 Which diseases are treated with antibiotics? cholera A B D TB measles C

Accepted Answer

A

Question 35

35 Which are specific immune responses? 1 phagocytosis 2 production of antibodies 3 effect of histamine A 1 only B 2 only C 1 and 3 only D 2 and 3 only

Accepted Answer

B

Question 36

36 Why has vaccination failed to eradicate cholera? A The pathogen exists in many strains which mutate. B The pathogen is present in the lumen of the gut. C The pathogen is waterborne. D There is a stage of the life cycle in other mammals.

Accepted Answer

B

Question 37

37 A person’s blood group is determined by antigens present on the red blood cells. Most people have antibodies in their blood plasma even if they have never received a blood transfusion. It is these antibodies in the plasma of the person who receives the blood which makes some blood transfusions unsafe. The table shows the antigens and antibodies in the blood of people with different blood groups. blood group antigens on red blood cells antibodies in plasma A A antibodies to B B B antibodies to A AB A and B no antibodies to A and B O neither A nor B antibodies to A and B Which are the blood groups of people who can safely receive blood from a person who has blood group A? A A and AB B A and O C B and O D AB only

Accepted Answer

A

Question 38

38 The diagram shows the flow of energy between organisms in an ecosystem. 1 2 3 4 Which correctly identifies each organism in the ecosystem? 1 2 3 4 A primary decomposers secondary producers consumers consumers B primary secondary producers decomposers consumers consumers C secondary decomposers producers primary consumers consumers D secondary primary decomposers producers consumers consumers

Accepted Answer

C

Question 39

39 In a freshwater food chain, which involves the least efficient energy transfer? A Large fishes feed on the small fishes. B Small fishes feed on the water fleas. C Unicellular algae trap sunlight. D Water fleas feed on the unicellular algae.

Accepted Answer

C

Question 40

40 Which statement concerning events occurring in the nitrogen cycle is not correct? A Free-living nitrogen-fixing bacteria release organic nitrogen compounds into the soil where bacteria convert these to nitrites and nitrates. B Nitrifying bacteria cause an increase in nitrate ions which are used by plants to make proteins. C Nitrogen-fixing bacteria use atmospheric nitrogen which is replaced by the action of denitrifying bacteria in waterlogged soil. D Saprophytic bacteria and fungi decompose organic nitrogen compounds excreted and egested by producers and consumers.

Accepted Answer

D

Question paper16 pages

Mark scheme2 pages

Questions as text

Q1 · When making measurements in experiments, which methods could have parallax errors?

Q2 · Which part of the cell is often continuous with the rough endoplasmic reticulum?

Q3 · Which structures are found in both chloroplasts and mitochondria?

Q4 · Tay-Sachs disease occurs when cells are unable to produce an enzyme, leading to a build…

Q5 · Which structures are present in a cell of Plasmodium?

Q6 · The diagram shows a triglyceride molecule that has been partially hydrolysed

Question 7

Q8 · Which correctly matches the functional and structural features of cellulose, collagen…

Q9 · The diagram shows the relationship between the levels of protein structure and bonds

Q10 · How many molecules of oxygen are bound to one molecule of haemoglobin, when it is fully…

Q11 · Why do large increases in the temperature or pH alter enzyme activity?

Q12 · Ethylene glycol is a chemical used to prevent water from freezing

Q13 · Increasing which type of bond helps to increase the fluidity of the cell surface membrane?

Q14 · The diagram shows three routes, X, Y and Z, through which substances can pass across a…

Q15 · In plants adapted to cold conditions, their cell surface membranes change as the weather…

Q16 · Which statement about a diploid cell is not correct?

Q17 · Laboratory mice whose p53 genes had been switched off developed tumours

Q18 · The diagram shows part of a DNA molecule

Q19 · Some antibiotics work by binding to ribosomes and preventing protein synthesis

Q20 · Which statements about tRNA are correct?

Q21 · What is the main function of a companion cell in phloem tissue?

Q22 · How does sucrose move from chloroplasts to the phloem?

Q23 · A large number of aphids were used to collect samples of the contents of the sieve tube…

Q24 · Which row is correct for the pulmonary vein?

Q25 · Which statement describes the Bohr effect?

Q26 · What is produced by the action of carbonic anhydrase?

Q27 · During the cardiac cycle, the movement of the valves causes sounds that can be heard…

Q28 · The following are all parts of the heart that control the heart action

Q29 · The photomicrograph shows a cross-section through a bronchus

Q30 · Which component(s) of tobacco smoke cause an increase in blood pressure and clot…

Q31 · Peak Flow is used in hospitals to diagnose some lung diseases

Q32 · The following are all methods of transmission of infectious diseases

Q33 · 40% of the world’s population live in an area where malaria is a threat to health

Q34 · Which diseases are treated with antibiotics?

Q35 · Which are specific immune responses?

Q36 · Why has vaccination failed to eradicate cholera?

Q37 · A person’s blood group is determined by antigens present on the red blood cells

Q38 · The diagram shows the flow of energy between organisms in an ecosystem

Q39 · In a freshwater food chain, which involves the least efficient energy transfer?

Q40 · Which statement concerning events occurring in the nitrogen cycle is not correct?

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