Cambridge A Level Biology 9700 — 2009 Oct/Nov Paper 1 · Variant 2
9700/12/O/N/09 · 40 questions · 40 marks · ≈45 min
The question paper and its mark scheme, free to read here and free to download. This is Cambridge’s own paper, exactly as it was sat.
Question paper16 pages
















Mark scheme2 pages
Answers below. Sit the paper first if you are practising.


Questions as text
Q1 · Which cell structure can be seen only with an electron microscope?
1 Which cell structure can be seen only with an electron microscope? A cell surface membrane B chromosome C nucleolus D vacuole
Mark scheme: A
Q2 · Which is a feature of all prokaryotic cells?
2 Which is a feature of all prokaryotic cells? A absence of cell surface membrane B division by mitosis C presence of cellulose cell wall D presence of ribosomes
Mark scheme: D
More questions on Cells as the basic units of living organisms
Q3 · A lymphocyte has a diameter of 1 × 10–2 millimetres (mm)
3 A lymphocyte has a diameter of 1 × 10–2 millimetres (mm). What is the diameter in nanometres (nm)? A 1 × 101 B 1 × 102 C 1 × 103 D 1 × 104
Mark scheme: D
Q4 · Which plan diagram of a transverse section of a leaf correctly shows the position of…
4 Which plan diagram of a transverse section of a leaf correctly shows the position of xylem and phloem as well as the fact that the palisade mesophyll is twice as thick as the spongy mesophyll? A B xylem phloem phloem xylem C D xylem phloem phloem xylem
Mark scheme: C
Q5 · The photomicrograph of a cell has a 2 cm scale line labelled 5 µm
5 The photomicrograph of a cell has a 2 cm scale line labelled 5 µm. 5 µm What is the magnification of the photomicrograph? A 1 × 103 B 2 × 103 C 4 × 103 D 5 × 103
Mark scheme: C
Q6 · What is a function of the smooth endoplasmic reticulum?
6 What is a function of the smooth endoplasmic reticulum? A protein synthesis B protein transport C steroid synthesis D steroid transport
Mark scheme: C
More questions on Cells as the basic units of living organisms
Q7 · Which combination of bond types correctly shows the weak and strong bonds that hold a…
7 Which combination of bond types correctly shows the weak and strong bonds that hold a molecule of protein in shape? types of bond hydrogen disulfide ionic A strong strong weak B strong weak strong C weak strong strong D weak strong weak
Mark scheme: D
Q8 · Which statement is true for cellulose, but not true for protein?
8 Which statement is true for cellulose, but not true for protein? A It is found in cell surface membranes. B It is synthesised from identical sub-units. C It is used as an energy source. D It may be a structural component.
Mark scheme: B
Q9 · The diagram shows a triglyceride molecule that has been partially hydrolysed
9 The diagram shows a triglyceride molecule that has been partially hydrolysed. H H C OH H C OH O H H H H H H H H H H C O C C C C C C C C C H C H C H H H H H H H H H C H H C H H C H H C H H C H H C H C H H H What will be the products of the total hydrolysis of the molecule shown? A a molecule of glycerol and a saturated fatty acid molecule only B a molecule of glycerol and an unsaturated fatty acid molecule only C a molecule of water, a molecule of glycerol and a saturated fatty acid molecule D a molecule of water, a molecule of glycerol and an unsaturated fatty acid molecule
Mark scheme: B
Q10 · The diagram shows a tripeptide molecule
10 The diagram shows a tripeptide molecule. H H O H C C C OH H H NH 1 H O H H C C C C 2 O H H 3 NH H H H C C C 4 O H NH2 At which two points will hydrolysis occur to release three amino acids? A 1 and 2 B 1 and 3 C 2 and 3 D 2 and 4
Mark scheme: D
Q11 · Which combination of procedures would not be used in a food test?
11. Which combination of procedures would not be used in a food test? use biuret use Benedict’s boil with use heat : ; reagent reagent dilute acid A Jv Jv B Jv Jv Cc Jv Jv Jv D
Mark scheme: B
Q12 · HIV-1 protease is an enzyme produced by the HIV virus
12 HIV-1 protease is an enzyme produced by the HIV virus. Two identical chains of 99 amino acids form the enzyme. In each chain, amino acids 25, 26 and 27 in the sequence form part of the active site. Which orders of protein structure control the shape of the active site? A primary, secondary, tertiary and quaternary B primary, secondary and tertiary only C primary and quaternary only D quaternary only
Mark scheme: A
Q13 · Which features of collagen result in it having high tensile strength?
13 Which features of collagen result in it having high tensile strength? 1 covalent bonds form between adjacent molecules 2 each three-stranded molecule is held together by hydrogen bonds 3 every third amino acid in the polypeptide is small 4 the primary structure is held together by peptide bonds A 1 and 2 B 1, 2 and 3 C 1, 3 and 4 D 2, 3 and 4
Mark scheme: B
Q14 · The diagram shows a red blood cell and the concentrations of ions, in mmol dm−3, in the…
14 The diagram shows a red blood cell and the concentrations of ions, in mmol dm−3, in the plasma and in the cell. Na+ 15 K+ 150 Cl 73 Na+ 144 K+ 5 Cl 111 Which ions are actively transported into and out of the cell? into cell out of cell A Cl − K+ B K+ Na+ C Na+ Cl − D Na+ K+
Mark scheme: B
Q15 · Diagrams 1 and 2 show how the transverse section through a leaf changes when moved from…
15 Diagrams 1 and 2 show how the transverse section through a leaf changes when moved from one solution W to a different solution Y. X X W Y diagram 1 diagram 2 How has the water potential changed in diagram 2? difference in cells at X in solution Y compared to difference in solution Y the same cells in compared to solution W solution W A less negative less negative B less negative more negative C more negative less negative D more negative more negative
Mark scheme: A
Q16 · In an experiment, 5 cm3 of 1 % salivary amylase are added to 100 cm3 of different…
16 In an experiment, 5 cm3 of 1 % salivary amylase are added to 100 cm3 of different concentrations of starch. Which graph shows the results of plotting the initial rate of reaction (y-axis) against the concentration of substrate (x-axis)? A B 0 0 C D 0 0
Mark scheme: A
Q17 · Cystic fibrosis is a disease where Cl – ions are unable to be transported into cells
17 Cystic fibrosis is a disease where Cl – ions are unable to be transported into cells. Which structure in the cell surface membrane is faulty? A B C D
Mark scheme: C
Q18 · Cancer cells divide out of control, forming tumours
18 Cancer cells divide out of control, forming tumours. Which statement describes the difference between a cancer cell and a normal cell? A Cancer cells do not undergo cytokinesis. B Cancer cells have a shorter interphase. C Cancer cells do not have metaphase. D Only cancer cells have mutated DNA.
Mark scheme: B
More questions on Replication and division of nuclei and cells
Q19 · Which statement describes a cell that is capable of reproduction and belonging to a…
19 Which statement describes a cell that is capable of reproduction and belonging to a haploid organism? A It has chromosomes that contain one polynucleotide chain. B It is capable of carrying out a reduction division to form gametes. C It possesses two copies of each gene as a result of fertilisation. D It will undergo cell division by mitosis during asexual reproduction.
Mark scheme: D
More questions on Replication and division of nuclei and cells
Q20 · During which stage of the mitotic cell cycle is DNA replicated?
20 During which stage of the mitotic cell cycle is DNA replicated? A anaphase B interphase C prophase D telophase
Mark scheme: B
More questions on Replication and division of nuclei and cells
Q21 · What does the enzyme DNA polymerase synthesise in a cell?
21 What does the enzyme DNA polymerase synthesise in a cell? A a polypeptide using DNA as a template B a strand of DNA using a polypeptide as a template C a strand of DNA using DNA as a template D a strand of mRNA using DNA as a template
Mark scheme: C
More questions on Structure of nucleic acids and replication of DNA
Q22 · The following statements describe events that take place during DNA replication and…
22 The following statements describe events that take place during DNA replication and transcription. Which statement is not correct? DNA transcription replication A adenine pairs with thymine yes no B both DNA polynucleotide chains act as templates yes no C the original DNA molecule is changed after the process no yes D uracil pairs with adenine no yes
Mark scheme: C
More questions on Structure of nucleic acids and replication of DNA
Q23 · A peptide consists of ten amino acids of four different kinds
23 A peptide consists of ten amino acids of four different kinds. What is the theoretical minimum number of tRNA molecules required to translate the mRNA for this peptide? A 4 B 10 C 12 D 30
Mark scheme: A
Q24 · Which diagram shows the semi-conservative replication of a section of a molecule of DNA?
24 Which diagram shows the semi-conservative replication of a section of a molecule of DNA? A B T T A T U A G G C G G C G P G C G P G C P P C C G C C G P P A P T A P T A A P P G P C G P C G G T A T A T A T A C G C G T U A P P T A P P T C G G C G G P P P P C G G C G G P P P P T A A T A A G C C G C C A T T A U T C D U A T A G C G C G C G C C G C G A U A T G C G C U A T A U A T A C G C G T U A P P A U A P P A T P P P P C G C G C G C G P P P P P P P P C G C G C G C G P P P P P P P P U A T A T A U A G C G C G C G C A T A U A U A T
Mark scheme: A
More questions on Structure of nucleic acids and replication of DNA
Q25 · What is the sequence of events in the translocation of assimilates?
25 What is the sequence of events in the translocation of assimilates? A active loading of sucrose into sieve elements via companion cells at the source, increased hydrostatic pressure, mass flow, unloading at the sink B hydrolysis of storage compounds in sinks, lowered water potential in sink, unloading of sucrose from sieve elements down the water potential gradient, mass flow from the source C lowered pressure in sieve elements at the source, movement of sucrose down the pressure gradient from companion cells, mass flow down a diffusion gradient to the sink D mass flow of dissolved sucrose via companion cells into the sieve element at the source, lowered hydrostatic pressure, diffusion of sucrose down concentration gradient to sink, active unloading
Mark scheme: A
Q26 · Which description states some of the features of xylem vessels?
26 Which description states some of the features of xylem vessels? A cells joined to form a tube, pits at intervals, sieve plates between cells, surrounded by the endodermis in roots B contains cells joined end to end, containing peripheral cytoplasm, cell walls with secondary thickening of lignin, located to the outside of phloem in vascular bundles C contains elongated cells with end walls broken down, located in vascular bundles in the stem and centrally in the roots D dead elongated cells, lignified cell walls with pits at intervals, associated with companion cells in the roots only
Mark scheme: C
Q27 · The diagram shows the changes in pressure potential (ΨP), solute potential (ΨS) and water…
27 The diagram shows the changes in pressure potential (ΨP), solute potential (ΨS) and water potential (Ψ) when a plasmolysed plant cell is placed in pure water. + X kPa 0 time Y Z – Which shows the correct curves for each potential? X Y Z A Ψ ΨP ΨS B ΨP ΨS Ψ C ΨS Ψ ΨP D ΨP Ψ ΨS
Mark scheme: D
Q28 · The graph shows the percentage saturation of haemoglobin with oxygen at different partial…
28 The graph shows the percentage saturation of haemoglobin with oxygen at different partial pressures of oxygen. Which range of partial pressures of oxygen produces the greatest change of percentage saturation of haemoglobin per unit oxygen tension? 100 D D D C C C 80 60 B B B % saturation of haemoglobin with oxygen 40 A A A 20 0 0 5 10 15 20 partial pressure of oxygen / kPa (oxygen tension)
Mark scheme: B
Q29 · When stained, which features, visible under the light microscope, are part of the cells…
29 When stained, which features, visible under the light microscope, are part of the cells of the plant tissues listed in the table? xylem elements sieve tube elements companion cells A cytoplasm lignin nuclei B lignin cytoplasm nuclei C lignin nuclei cytoplasm D nuclei cytoplasm lignin
Mark scheme: B
Q30 · A disease damages alveoli
30 A disease damages alveoli. Which effect does this have on the gas exchange surface area and volume of the lungs? surface area volume A decreased decreased B decreased no change C increased increased D increased no change
Mark scheme: B
Q31 · An oxygen molecule diffuses directly from the air in an alveolus to haemoglobin in a red…
31 An oxygen molecule diffuses directly from the air in an alveolus to haemoglobin in a red blood cell. What is the minimum number of cell surface membranes through which this molecule must pass? A 2 B 3 C 4 D 5
Mark scheme: D
Q32 · What would be seen in an electron micrograph of a bronchus wall?
32 What would be seen in an electron micrograph of a bronchus wall? 1 cartilage cells 2 ciliated cells 3 exocytotic vesicles A 1 and 2 B 1 and 3 C 2 and 3 D 1, 2 and 3
Mark scheme: D
Q33 · Below are correct statements comparing blood, tissue fluid and lymph in a capillary bed
33 Below are correct statements comparing blood, tissue fluid and lymph in a capillary bed. • W lacks large plasma proteins and red blood cells and has a higher water potential than Z. • X is at a lower pressure than Y and contains red blood cells and large plasma proteins. • Y is at a higher pressure than W and contains red blood cells and large plasma proteins. • Z is at a lower pressure than Y and lacks red blood cells. Which correctly identifies W, X, Y and Z? W X Y Z blood entering blood leaving A lymph tissue fluid capillary capillary blood leaving blood entering B lymph tissue fluid capillary capillary blood entering blood leaving C lymph tissue fluid capillary capillary blood leaving blood entering D tissue fluid lymph capillary capillary
Mark scheme: D
Q34 · After an immune response, memory cells remain in the blood for a long time
34 After an immune response, memory cells remain in the blood for a long time. What is the function of memory cells? A They can ingest invading bacteria. B They contain lots of antibodies. C They divide to make plasma cells. D They kill cells infected with virus.
Mark scheme: C
Q35 · What are produced by B-lymphocytes?
35 What are produced by B-lymphocytes? killer lymphocyte memory cells plasma cell clones clones A v v x B v x v Cc v v v D x v v
Mark scheme: D
Q36 · Scientists are concerned that avian (bird) flu caused by the H5N1 virus, could infect…
36 Scientists are concerned that avian (bird) flu caused by the H5N1 virus, could infect humans and cause a pandemic. If this occurs, which factors could help prevent humans spreading the disease? 1 killing all poultry 2 reducing all air flights 3 taking a course of antibiotics A 1 only B 2 only C 3 only D 1, 2 and 3
Mark scheme: B
Q37 · A country has fewer than 2.5 deaths per 100 000 people from TB in one year and the next…
37 A country has fewer than 2.5 deaths per 100 000 people from TB in one year and the next year this rose to 25 deaths per 100 000. What may have contributed to this change? 1 decrease in contact tracing 2 increase in refugee camps 3 water supply contaminated by sewage A 1 and 2 B 1 and 3 C 2 and 3 D 1, 2 and 3
Mark scheme: A
Q38 · The diagram shows an arctic ecosystem
38 The diagram shows an arctic ecosystem. polar bear glaucous gull ringed seal little auk arctic cod squid amphipods shrimps herbivorous copepods phytoplankton sunlight How many trophic levels are represented? A 3 B 4 C 5 D 6
Mark scheme: D
Q39 · A tree carries out photosynthesis and provides organic compounds for other organisms in a…
39 A tree carries out photosynthesis and provides organic compounds for other organisms in a forest. It takes carbon dioxide from and returns oxygen to the atmosphere. It takes water from the soil into its roots and its leaves lose water to the atmosphere. Many other organisms live in the tree. Which term applies to the description of the tree? A ecosystem B habitat C niche D trophic level
Mark scheme: C
Q40 · In an investigation, discs of 2.5 cm diameter were cut from leaves
40 In an investigation, discs of 2.5 cm diameter were cut from leaves. Fifty discs were put into three identical bags with different net sizes and buried in newly dug soil at a depth of 3 cm. At 60 day intervals the bags were dug up and the leaf discs measured to see how much of the leaf area had disappeared. The table shows the percentage of leaf discs remaining in each bag. percentage of leaf disks remaining time / days net size 7 mm net size 0.5 mm net size 0.03 mm 0 100 100 100 60 80 94 100 120 30 81 100 180 14 67 100 240 9 63 100 300 6 61 100 Which organisms are most important for breaking down the leaves? A earthworms and beetles B microorganisms only C small invertebrates only D small invertebrates and microorganisms
Mark scheme: A
What was in this paper
The subtopics covered by these 40 questions, and how many questions each got. Open one in a new tab to see every Cambridge question on it.
4Movement into and out of cells3Replication and division of nuclei and cells3Structure of nucleic acids and replication of DNA3Structure of transport tissues3The gas exchange system3The microscope in cell studies3Biodiversity2Carbohydrates and lipids2Cells as the basic units of living organisms2Infectious diseases2The immune system2Conservation1Factors that affect enzyme action1Fluid mosaic membranes1Protein synthesis1Testing for biological molecules1The circulatory system1Transport mechanisms1Transport of oxygen and carbon dioxide1