Cambridge A Level Biology 9700 — 2008 Oct/Nov Paper 1 · Variant 1

Question 1

1 Which eyepiece and objective lens combination enables you to see the greatest number of cells in the field of view? eyepiece objective A ×5 ×10 B ×10 ×10 C ×5 ×40 D ×10 ×40

Accepted Answer

A

Question 2

2 From which cell organelle are nucleic acids absent? A chloroplast B Golgi apparatus C mitochondrion D ribosome

Accepted Answer

B

Question 3

3 Mitochondria are thought to have evolved from prokaryotic cells that were ingested by an ancestral cell. Which feature have the prokaryotes lost during their evolution into mitochondria? A cell wall B circular chromosome C endoplasmic reticulum D ribosomes

Accepted Answer

A

Question 4

4 The diagram is a drawing made from an electron micrograph showing a cross-section of an alveolus and two adjacent capillaries. alveolar air space fibre-secreting cell ×2500 What is the shortest distance travelled by an oxygen molecule diffusing from the alveolar air space into one of the red blood cells? A 1.0 µm B 3.0 µm C 10.0 µm D 30.0 µm

Accepted Answer

B

Question 5

5 = Which combination is found in a prokaryotic cell?

endoplasmic

reticulum DNA RNA nucleus
A JV JV x x
B J x x y
Cc x V4 J x
D x x J V

key
Jv = present

X = absent

Accepted Answer

C

Question 6

6 Which diagram shows part of a structural polysaccharide? O O O O A ..... O O O O O ..... O O O O B ..... O O O O O ..... O O C ..... O O O O O O O ..... O O D O

Accepted Answer

B

Question 7

7 Which substances contain carbon, hydrogen, oxygen and nitrogen? 1 amylopectin 2 collagen 3 deoxyribonucleic acid A 2 only B 1 and 2 only C 2 and 3 only D 1, 2 and 3

Accepted Answer

C

Question 8

8 Sucrose is a disaccharide formed from two hexose sugars, α-glucose (alpha-glucose) and fructose. Which pair of monosaccharide structures will be formed when sucrose is hydrolysed? CH2OH CH2OH H O H H O OH H H A OH H OH H OH OH OH H H OH H OH CH2OH CH2OH H O H H O H H H B OH H OH H OH OH OH OH H OH H OH CH2OH HOCH2 O CH2OH H O H H H OH C OH H H OH OH OH OH H H OH CH2OH HOCH2 O CH2OH H O OH H H OH D OH H H OH OH H OH H H OH

Accepted Answer

C

Question 9

9 A number of different types of bonds maintain the structure of proteins. These include disulphide, hydrogen and ionic bonds, as well as hydrophobic interactions. Some of these are stronger than others. Which are the strongest? A disulphide bonds B hydrogen bonds C hydrophobic interactions D ionic bonds

Accepted Answer

A

Question 10

10 Haemoglobin is a globular protein consisting of four polypeptide chains – 2 alpha chains and 2 beta chains. In normal individuals, in the DNA which codes for each beta chain, the sixth triplet has a code for glutamic acid. In individuals with sickle cell anaemia this base triplet changes and codes for valine. What aspect of the haemoglobin molecule does this mutation change? A the iron content B the primary structure C the quaternary structure D the secondary structure

Accepted Answer

B

Question 11

11 Which type of molecule contains disulphide bonds and which contains glycosidic bonds? disulphide bonds glycosidic bonds A glycoprotein polysaccharide B nucleic acid glycoprotein C polysaccharide nucleic acid D protein triglyceride

Accepted Answer

A

Question 12

12 The rate of an enzyme controlled reaction was measured at temperatures within the range 10 - 60 °C. Which curve represents the most usual relationship between temperature and enzyme activity? A B rate of rate of reaction reaction 0 0 10 60 10 60 temperature / °C temperature / °C C D rate of rate of reaction reaction 0 0 10 60 10 60 temperature / °C temperature / °C

Accepted Answer

D

Question 13

13 The water potential of three adjacent plant cells is shown. X Y –250 kPa –1000 kPa Z –4000 kPa In which direction will water move? A from cell X to cell Y and then cell Z only B from cell X to both cells Y and Z C from cell Z to cell Y and then cell X only D from cell Z to both cells Y and X

Accepted Answer

B

Question 14

14 The table shows three processes that contribute to transport across cell surface membranes.

Which processes are the result of random movement of molecules?

diffusion endocytosis osmosis
A x x x
B x v v
Cc v x v
D v v x

<
I

key

qj
I

random

non random

Accepted Answer

C

Question 15

15 The epithelial cells of people with cystic fibrosis have a defect in the structure of the cell surface membrane. The ability of the cell to transport chloride ions out of the cell is affected. Which membrane component is involved? A cholesterol B glycolipid C phospholipid D protein

Accepted Answer

D

Question 16

16 The diagram shows part of the cell surface membrane. 1 2 3 4 5 Which components help to maintain the fluidity of the membrane? A 1 and 3 B 1 and 4 C 2 and 4 D 3 and 5

Accepted Answer

D

Question 17

17 Which statement describes events during interphase of the mitotic cell cycle? A Chromatids are pulled apart by spindle fibres. B Chromosomes are replicated ready for the next division. C Chromosomes line up on the equator of the spindle. D Chromosomes start to coil, becoming shorter and fatter.

Accepted Answer

B

Question 18

18 Chromosome telomeres promote DNA replication and are not completely replaced during mitosis. A substance X is known that completely replaces telomeres during mitosis. What will be the effect of growing a cell culture with and without substance X? with substance X without substance X A cells divide continually cell division eventually slows and stops B cells divide more rapidly cells divide continually C cell division eventually slows cell division stops immediately and stops D cell division stops immediately cells divide continually

Accepted Answer

A

Question 19

19 What is a correct description of the centrioles, nuclear envelope and spindle during mitosis in animal cells? phase centrioles nuclear envelope spindle A anaphase replicate absent present B metaphase present reforms present C prophase move apart breaks up forms D telophase replicate breaks up breaks up

Accepted Answer

C

Question 20

20 Which diagram shows the bond linking the individual units of a nucleic acid? A B C D H C O C C C O C C N C C C O P O C O O

Accepted Answer

C

Question 21

21 What is the function of the enzyme RNA polymerase? A to form a polypeptide using mRNA as a template B to form a strand of DNA using mRNA as a template C to form a strand of mRNA using DNA as a template D to form a strand of mRNA using tRNA as a template

Accepted Answer

C

Question 22

22 The table gives the tRNA anticodons for four amino acids. amino acid anticodon (tRNA) asparagine UUA glutamic acid CUU proline GGA threonine UGG A cell makes a polypeptide with the amino acid sequence: glutamic acid – asparagine – threonine – proline What was the sequence of bases on the strand of the DNA which was complimentary to the mRNA from which this polypeptide was formed? A CTTTTATGGGGA B CUUUUAUGGGGA C GAAAATACCCCT D GAAAAUACCCCU

Accepted Answer

A

Question 23

23 Four solutions, with different water potentials are listed. 1 endodermal cell solution 2 root hair cell solution 3 soil water solution 4 solution in a xylem vessel Which list has the solutions in order from the highest (least negative) water potential to the lowest (most negative) water potential? highest lowest A 1 2 3 4 B 2 4 1 3 C 3 2 1 4 D 4 1 3 2

Accepted Answer

C

Question 24

24 Which feature of a root hair cell is not an adaptation for water uptake from the soil solution? A lack of a waxy cuticle B large numbers of mitochondria C long, thin extension to the cell D thin cellulose cell wall

Accepted Answer

B

Question 25

25 The diagram shows a model to demonstrate the mass-flow hypothesis of translocation. W water concentrated dilute sucrose solution Y X Z sucrose solution partially permeable partially permeable membrane membrane In a plant, what are the structures W, X, Y and Z and what is the direction of flow of solution along W? phloem xylem roots leaves direction of flow along W A W X Y Z From Z to Y B W X Z Y From Y to Z C X W Y Z From Y to Z D X W Z Y From Z to Y

Accepted Answer

B

Question 26

26 The graph shows the dissociation curves for adult haemoglobin at two different (unidentified) concentrations of carbon dioxide. Which point represents the oxygen concentration in red cells as they leave a resting muscle? 100 75 A % saturation of haemoglobin 50 B with oxygen D 25 C 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 partial pressure of O2 / kPa

Accepted Answer

D

Question 27

27 Which chamber of the heart shows the greatest pressure changes during one cardiac cycle? A left atrium B left ventricle C right atrium D right ventricle

Accepted Answer

B

Question 28

28 What happens to the blood flow in the cardiac cycle? A Blood flows into the aorta through the semilunar valve due to contraction of the right ventricle. B Blood flows into the left atrium through the pulmonary artery when the walls of the left atrium relax. C Blood flows into the right atrium through the vena cava when the walls of the right atrium relax. D Blood flows into the right ventricle through the semilunar valve when the walls of the right atrium contract.

Accepted Answer

C

Question 29

29 The squamous epithelial cells of the alveoli form part of the gas exchange system. How do these cells assist gas exchange? 1 They contain many mitochondria. 2 They have a large surface area. 3 They provide a short diffusion path. A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

Accepted Answer

C

Question 30

30 Which statements are correct effects of tar in tobacco smoke on the human gas exchange

system?
goblet cells are mucus glands in mutations may occur | the activity of cilia
stimulated to the trachea are in epithelial cells in the airays is
secrete more mucus enlarged forming tumors inhibited

0 0O WwW >
<< x
x KM
S44
<4 x

Accepted Answer

C

Question 31

31 The diagram shows a record of a person’s breathing. The person breathed normally at the start, breathed in as deeply as possible and then breathed out as much as possible. start 1 dm3 30 seconds What is a valid conclusion from the graph? A The person breathed in 1000 cm3 during the first 50 seconds. B The person was carrying out strenuous exercise for the first 30 seconds. C The rate of breathing for the first 30 seconds was 18 breaths per minute. D The tidal volume was 500 cm3, the vital capacity was 3750 cm3.

Accepted Answer

D

Question 32

32 Ciliated, goblet and squamous epithelial cells are found in various parts of the human lung and associated structures. Where are these cells located? squamous ciliated goblet epithelial A bronchiole trachea alveolus B bronchus bronchiole pulmonary vein C trachea pulmonary vein alveolus D trachea bronchus bronchiole

Accepted Answer

A

Question 33

33 Some antibiotics are used in animal feed to reduce disease. What explains why these antibiotics should not be used in the treatment of human diseases? A Humans may be allergic to these antibiotics. B Human cells may stop responding to these antibiotics. C Pathogenic bacteria may develop resistance to these antibiotics. D Useful gut bacteria may be killed by these antibiotics.

Accepted Answer

C

Question 34

34 Some children are born with Severe Combined Immune Deficiency (SCID). These children do not normally have any T-lymphocytes and suffer from many diseases. How can these children be cured? A bone marrow transplantation B continual use of antibiotics C transfusion of antibodies D vaccination against all diseases

Accepted Answer

A

Question 35

35 The diagram represents the structure of a molecule of antibody. Y Z X Which arrangement of labels X, Y and Z correctly identifies its different parts? X Y Z A antigen binding site constant region variable region B constant region antigen binding site variable region C constant region variable region antigen binding site D variable region antigen binding site constant region

Accepted Answer

C

Question 36

36 Which of the following are increasing the spread of malaria? 1 continued migration of people due to war and civil unrest 2 increasing carbon dioxide levels causing global warming 3 increasing resistance to antibiotics and other drugs A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

Accepted Answer

D

Question 37

37 Which examples show the different types of immunity? active artificial passive natural A immunity to measles after infection receiving antibodies to measles in colostrum B immunity to measles after infection receiving antibodies to tetanus by injection C immunity to smallpox after vaccination receiving antibodies to measles in colostrum D immunity to smallpox after vaccination receiving antibodies to tetanus by injection

Accepted Answer

C

Question 38

38 The diagram shows a simplified nitrogen cycle. During which stage does nitrification take place? nitrogen in atmosphere A plant animal proteins proteins D death and decay B ammonium compounds C nitrites nitrates

Accepted Answer

C

Question 39

39 Grasshoppers eat only the leaves of grass. Grasshoppers are eaten by carnivorous beetles. What does this description of grasshoppers give us sufficient information to define? 1 habitat 2 niche 3 trophic level A 2 only B 3 only C 2 and 3 only D 1, 2 and 3

Accepted Answer

B

Question 40

40 Of the prey consumed by the lion, into which box does the largest amount of energy go? B C energy used in growth, energy lost as repair and reproduction heat from A respiration energy lost in urine energy assimilated energy consumed energy consumed energy lost in faeces D

Accepted Answer

C

Question paper20 pages

Mark scheme2 pages

Questions as text

Q1 · Which eyepiece and objective lens combination enables you to see the greatest number of…

Q2 · From which cell organelle are nucleic acids absent?

Q3 · Mitochondria are thought to have evolved from prokaryotic cells that were ingested by an…

Q4 · The diagram is a drawing made from an electron micrograph showing a cross-section of an…

Q5 · = Which combination is found in a prokaryotic cell?

Q6 · Which diagram shows part of a structural polysaccharide?

Q7 · Which substances contain carbon, hydrogen, oxygen and nitrogen?

Q8 · Sucrose is a disaccharide formed from two hexose sugars, α-glucose (alpha-glucose) and…

Q9 · A number of different types of bonds maintain the structure of proteins

Q10 · Haemoglobin is a globular protein consisting of four polypeptide chains – 2 alpha chains…

Q11 · Which type of molecule contains disulphide bonds and which contains glycosidic bonds?

Q12 · The rate of an enzyme controlled reaction was measured at temperatures within the range…

Q13 · The water potential of three adjacent plant cells is shown

Q14 · The table shows three processes that contribute to transport across cell surface membranes

Q15 · The epithelial cells of people with cystic fibrosis have a defect in the structure of the…

Q16 · The diagram shows part of the cell surface membrane

Q17 · Which statement describes events during interphase of the mitotic cell cycle?

Q18 · Chromosome telomeres promote DNA replication and are not completely replaced during…

Q19 · What is a correct description of the centrioles, nuclear envelope and spindle during…

Q20 · Which diagram shows the bond linking the individual units of a nucleic acid?

Q21 · What is the function of the enzyme RNA polymerase?

Q22 · The table gives the tRNA anticodons for four amino acids

Q23 · Four solutions, with different water potentials are listed

Q24 · Which feature of a root hair cell is not an adaptation for water uptake from the soil…

Q25 · The diagram shows a model to demonstrate the mass-flow hypothesis of translocation

Q26 · The graph shows the dissociation curves for adult haemoglobin at two different…

Q27 · Which chamber of the heart shows the greatest pressure changes during one cardiac cycle?

Q28 · What happens to the blood flow in the cardiac cycle?

Q29 · The squamous epithelial cells of the alveoli form part of the gas exchange system

Q30 · Which statements are correct effects of tar in tobacco smoke on the human gas exchange…

Q31 · The diagram shows a record of a person’s breathing

Q32 · Ciliated, goblet and squamous epithelial cells are found in various parts of the human…

Q33 · Some antibiotics are used in animal feed to reduce disease

Q34 · Some children are born with Severe Combined Immune Deficiency (SCID)

Q35 · The diagram represents the structure of a molecule of antibody

Q36 · Which of the following are increasing the spread of malaria?

Q37 · Which examples show the different types of immunity?

Q38 · The diagram shows a simplified nitrogen cycle

Q39 · Grasshoppers eat only the leaves of grass

Q40 · Of the prey consumed by the lion, into which box does the largest amount of energy go?

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