Cambridge A Level Biology 9700 — 2008 May/June Paper 1 · Variant 1

Question 1

1 What is the order of size of cell components? largest smallest A centrioles mitochondria lysosomes nucleoli B mitochondria nucleoli lysosomes centrioles C nucleoli mitochondria centrioles lysosomes D nucleoli centrioles mitochondria lysosomes

Accepted Answer

B

Question 2

2 When mucus is secreted from a goblet cell in the trachea, these events take place. 1 addition of carbohydrate to protein 2 fusion of the vesicle with the plasma membrane 3 secretion of a glycoprotein 4 separation of a vesicle from the Golgi apparatus What is the sequence in which these events take place? A 1 → 4 → 2 → 3 B 1 → 4 → 3 → 2 C 4 → 1 → 2 → 3 D 4 → 1 → 3 → 2

Accepted Answer

A

Question 3

3 The magnification of this electron micrograph is 5 × 103. What is the actual size of the nucleolus? A 0.2 µm B 0.5 µm C 2 µm D 20 µm

Accepted Answer

C

Question 4

4 Which structure is present in cells of eukaryotes but not present in cells of prokaryotes? A 70s ribosome B chromatin C mesosome D plasmid

Accepted Answer

B

Question 5

5 A piece of mammalian tissue was homogenised and subjected to differential centrifugation to yield four subcellular fractions. The activity of four different types of enzyme, A, B, C and D, was investigated within each fraction. Which bar chart shows the results of investigating hydrolytic enzyme activity? A B C D key fraction containing L - lysosomes activity activity activity activity M - mitochondria N - nuclei R - ribosomes L M N R L M N R L M N R L M N R

Accepted Answer

D

Question 6

6 Samples of a food were tested using Benedict’s reagent, biuret solution and ethanol. After testing, the solutions were blue with Benedict’s reagent, purple with biuret and cloudy with ethanol. Which molecules do the samples contain? W X H CH2OH OH HO CH2 C C C O H H H O H N C C OH H OH OH CH3 CH2 C C H C C H O N H OH CH3 C C H O N H H Y Z HOCH2 H O H HOCH2 O O H H C O C R H H 1 2 O HO OH H O H HO CH2OH H C O C R H OH OH H O H C O C R H A W, X and Z B W, Y and Z C W, X and Y D X, Y and Z

Accepted Answer

B

Question 7

7 How is the shape of a polypeptide chain maintained when it is coiled into an α helix? A disulphide bonds B hydrogen bonds C hydrophobic interactions D ionic bonds

Accepted Answer

B

Question 8

8 The diagram shows an α 1 : 4 glycosidic bond. CH2OH CH2OH H H H O O H H H OH H O OH H OH OH H OH H OH Which molecules contain this bond? A amylose and cellulose B amylose but not cellulose C cellulose but not amylose D neither amylose nor cellulose

Accepted Answer

B

Question 9

9 Which combination describes a triglyceride?

hydrophilic soluble in alcohol
A v v
B x x
Cc v x
D x v

Accepted Answer

D

Question 10

10 What will break an ionic bond between amino acids? A condensation B hydrolysis C low temperature D pH change

Accepted Answer

D

Question 11

11 When hydrolysed, which molecules have products containing a carboxyl group? 1 phospholipids 2 polysaccharides 3 proteins A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

Accepted Answer

B

Question 12

12 The curve X shows the activity of an enzyme at 20 °C. Curves A, B, C and D show the effect of different conditions on the activity of the enzyme. Which curve shows the effect of increasing the temperature by 10 °C and adding extra substrate? A B amount of product C D X time

Accepted Answer

B

Question 13

13 Following a heart attack, the enzyme lactate dehydrogenase leaks into the blood plasma from

damaged heart muscle.

Which steps are required to obtain the best estimate of lactate dehydrogenase activity in a
sample of blood plasma?

a incubate with incubate with
sterilise blood
lasma by substrate for lactate
P heatin lactate dehydrogenase
g dehydrogenase inhibitor
A x J x
B Jv x J
Cc x J Jv
D Jv Jv J

key
/¥ = step required

X = step not required

Accepted Answer

A

Question 14

14 The diagram shows a cell from the gut. The cell produces protease enzymes. What is correct? enzymes released by ATP needed A endocytosis no B endocytosis yes C exocytosis no D exocytosis yes

Accepted Answer

D

Question 15

15 Membranes in cells include the following components. 1 cholesterol 2 glycoproteins 3 phospholipids 4 proteins Which component is the most important for these functions of membranes? transporting ions recognising self / separating stabilising the function through non self dissolved ions hydrophobic layer membranes A 1 2 3 4 B 2 3 1 4 C 3 1 4 2 D 3 4 1 2

Accepted Answer

B

Question 16

16 Strips of plant tissue were immersed in a range of sucrose solutions of different concentrations. Their lengths were measured before immersion and after 30 minutes in the different solutions. The graph shows the ratio of initial length to final length. 1.04 1.02 1.00 initial length final length 0.98 0.96 0.94 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 sucrose concentration / mol dm–3 Which concentration of sucrose solution, in mol dm–3, has the same water potential as the cell sap before immersion? A 0.1 B 0.25 C 0.45 D 0.8

Accepted Answer

C

Question 17

17 The diagram shows three routes through which substances can pass across a cell membrane. X Y Z Which correctly shows the routes for vitamin D, which is fat soluble, and vitamin C, which is water soluble? vitamin D vitamin C A Y X B X Z C X Y D Z Y

Accepted Answer

B

Question 18

18 Which are features of nuclear division by mitosis? 1 forms cells of equal size to the parent cell 2 forms genetically identical cells 3 semi-conservative replication of DNA A 1 and 2 only B 2 and 3 only C 2 only D 1, 2 and 3

Accepted Answer

C

Question 19

19 The diagram shows a cell of an organism formed by reduction division. What is the diploid number for this organism? A 10 B 20 C 40 D 46

Accepted Answer

C

Question 20

20 The graph shows three measurements obtained following metaphase of mitosis. 60 50 3 40 distance / µm 30 2 1 20 10 0 0 5 10 15 20 25 30 time / minutes What measurements do the curves represent? distance between distance between distance between centromeres and centromeres of sister poles of spindle poles of spindle chromatids A 1 2 3 B 1 3 2 C 3 1 2 D 3 2 1

Accepted Answer

A

Question 21

21 The RNA triplet UAG acts as a stop codon terminating the synthesis of a polypeptide. The diagram shows a strand of DNA which codes for four amino acids. Where would a mutation, introducing a thymine nucleotide, result in the termination of transcription? T C C A C T C G A T G C A B C D

Accepted Answer

B

Question 22

22 The diagram shows a process involving DNA. What is the name of the process and the stage in the cell cycle at which it occurs? process stage A replication interphase B replication prophase C transcription interphase D transcription prophase

Accepted Answer

A

Question 23

23 The diagram shows two bases, X and Y, joined by hydrogen bonds (----) in DNA. H O N H O N H C C C C C H N H C N N C Y N C C N X O H N H What are the correct bases? X Y A adenine cytosine B adenine uracil C cytosine guanine D cytosine thymine

Accepted Answer

C

Question 24

24 Part of the amino acid sequences in normal and sickle cell haemoglobin are shown. normal haemoglobin sickle cell haemoglobin thr-pro-glu-glu thr-pro-val-glu Possible mRNA codons for these amino acids are glutamine (glu) GAA GAG proline (pro) CCU CCC threonine (thr) ACU ACC valine (val) GUA GUG Which tRNA molecule is not involved in the formation of this part of the sickle cell haemoglobin? A B C D C U C U U A U C A U G G

Accepted Answer

D

Question 25

25 A large number of aphids were used to collect samples of the contents of the sieve tubes of a tomato plant. sieve tube element sample taken micopipette tomato plant stem (aphid and stem are not drawn to the same scale) Different samples of the sieve tube solution were tested. Which was the correct result? Benedict’s test iodine in KI before hydrolysis after hydrolysis A blue red brown B blue blue blue / black C red blue blue / black D red red brown

Accepted Answer

A

Question 26

26 The diagram shows a dendrograph fixed to a tree. The dendrograph records changes in the diameter of the tree. Some results are shown on the chart recording. dendrograph fixed to a tree chart recording tree chart diameter noon 12pm noon 12pm noon time of day What explains the diameter changes recorded during the day and night? A cohesive tension forces increased during the day B mass flow of sucrose increased during the night C root pressure decreased during the day D thermal expansion and contraction of water in the tree

Accepted Answer

A

Question 27

27 Which combination of features is characteristic of phloem sieve tubes? solute potential of lignification of the cell content the cell wall A high absent B high present C low absent D low present

Accepted Answer

C

Question 28

28 The diagram shows two cardiac cycles of a student, with the sequence of events set against a time scale. seconds 0 0.5 1.0 1.5 key AS = atrial systole VS = ventricular systole AS VS DIASTOLE AS VS DIASTOLE How many times per minute is the student’s heart beating? A 72 B 75 C 80 D 90

Accepted Answer

C

Question 29

29 The following graph shows the pressure changes in the left atrium, left ventricle and aorta during a cardiac cycle. 20 2 1 pressure / kPa 10 key left ventricle 3 4 aorta left atrium 0 –1 0 0.2 0.4 0.6 0.8 time / s With reference to the semilunar and bicuspid valves, what is happening at points 1, 2, 3 and 4? semi-lunar valve bicuspid valve opens closes opens closes A 1 2 3 4 B 1 2 4 3 C 2 3 1 4 D 2 3 4 1

Accepted Answer

B

Question 30

30 Which features of xerophytes reduce water loss by transpiration?

rolled leaves | swollen leaves | sunken stomata | thick waxy cuticle

0 OO DW >
<< x
SA 4
Ko 4
Ko 4

Accepted Answer

D

Question 31

31 Between 1954 and 1958 many doctors read a report that linked smoking cigarettes to deaths from lung cancer. The graph shows deaths from lung cancer among male doctors and ‘all other men’ in England and Wales between 1954 and 1962. 120 all other men +7 % 90 deaths from lung 60 cancer per male doctors 100 000 –38 % 30 0 1954 1958 1962 year Which statements best explain the changes in deaths from lung cancer between 1954 and 1962? 1 ‘All other men’ are more at risk of dying from lung cancer then male doctors. 2 Male doctors are more at risk of dying from lung cancer than ‘all other men’. 3 Proportionally more ‘all other men’ gave up smoking than male doctors. 4 Proportionally more male doctors gave up smoking cigarettes than ‘all other men’. A 1 and 3 B 2 and 3 C 2 and 4 D 1 and 4

Accepted Answer

D

Question 32

32 Which component of tobacco smoke affects blood pressure? A carbon dioxide B carbon monoxide C nicotine D tar

Accepted Answer

C

Question 33

33 Which tissues are present in a bronchus?

0 0O WwW >

cartilage

~*~ KOM

ciliated epithelium

K& 4

smooth muscle

<< x

Accepted Answer

A

Question 34

34 How would health improve if a person suffering from mild emphysema stopped smoking cigarettes? A goblet cells secrete more mucus, allowing a greater number of pathogens to be trapped B increased numbers of phagocytic macrophages arrive in the lungs C less atheroma build-up on the inner lining of arteries, increasing lumen diameter D less carboxyhaemoglobin produced, increasing oxygen transport by haemoglobin

Accepted Answer

D

Question 35

35 Which disease is treated with drugs that have a similar molecular structure to DNA nucleotides? A cholera B HIV / AIDS C malaria D tuberculosis (TB)

Accepted Answer

B

Question 36

36 Which factors would help prevent which disease? 1 covering water containers 2 disinfecting and chlorinating water 3 use of antiviral drugs 4 vaccination cholera malaria tuberculosis (TB) A 2 1 4 B 1 and 2 2 3 C 4 2 3 D 3 1 and 2 4

Accepted Answer

A

Question 37

37 Which future development in vaccine production is most important in the fight to eradicate measles in developing countries? A a combined vaccine to combat it and other diseases B a single vaccine, without the need for boosters C a vaccine containing only live measles viruses D a vaccine produced by genetic engineering techniques

Accepted Answer

B

Question 38

38 The following statements describe some of the stages in phagocytosis. 1 Bacteria become surrounded in a phagocytic vacuole. 2 Bacteria release chemicals that attract neutrophils. 3 Lysosomes fuse with the phagocytic vacuole. 4 Receptor proteins on the neutrophil bind to the bacteria. Which order defines the correct sequence for phagocytosis? A 3 2 4 1 B 2 4 1 3 C 4 1 3 2 D 1 3 2 4

Accepted Answer

B

Question 39

39 The diagram shows some chemical conversions during the nitrogen cycle.

nitrogen gas
in air

organic nitrogen in organic nitrogen
leguminous plants in soil

Which conversions involve microorganisms?

nitrates in
the soil

stage P Q R
A J x x key
B v v v ¥ = involves microorganisms
Cc x v v X = does not involve microorganisms
D x x x

Accepted Answer

B

Question 40

40 What is the correct match of example to ecological term? community ecosystem population niche A all lake organisms freshwater lake freshwater shrimps pond weed as primary producer B freshwater shrimps all lake organisms pond weed as freshwater lake primary producer C freshwater lake pond weed as freshwater shrimps all lake organisms primary producer D freshwater shrimps freshwater lake all lake organisms pond weed as primary producer

Accepted Answer

A

Question paper20 pages

Mark scheme2 pages

Questions as text

Q1 · What is the order of size of cell components?

Q2 · When mucus is secreted from a goblet cell in the trachea, these events take place

Q3 · The magnification of this electron micrograph is 5 × 103

Q4 · Which structure is present in cells of eukaryotes but not present in cells of prokaryotes?

Q5 · A piece of mammalian tissue was homogenised and subjected to differential centrifugation…

Q6 · Samples of a food were tested using Benedict’s reagent, biuret solution and ethanol

Q7 · How is the shape of a polypeptide chain maintained when it is coiled into an α helix?

Q8 · The diagram shows an α 1 : 4 glycosidic bond

Q9 · Which combination describes a triglyceride?

Q10 · What will break an ionic bond between amino acids?

Q11 · When hydrolysed, which molecules have products containing a carboxyl group?

Q12 · The curve X shows the activity of an enzyme at 20 °C

Q13 · Following a heart attack, the enzyme lactate dehydrogenase leaks into the blood plasma…

Q14 · The diagram shows a cell from the gut

Q15 · Membranes in cells include the following components

Q16 · Strips of plant tissue were immersed in a range of sucrose solutions of different…

Q17 · The diagram shows three routes through which substances can pass across a cell membrane

Q18 · Which are features of nuclear division by mitosis?

Q19 · The diagram shows a cell of an organism formed by reduction division

Q20 · The graph shows three measurements obtained following metaphase of mitosis

Q21 · The RNA triplet UAG acts as a stop codon terminating the synthesis of a polypeptide

Q22 · The diagram shows a process involving DNA

Q23 · The diagram shows two bases, X and Y, joined by hydrogen bonds (----) in DNA

Q24 · Part of the amino acid sequences in normal and sickle cell haemoglobin are shown

Q25 · A large number of aphids were used to collect samples of the contents of the sieve tubes…

Q26 · The diagram shows a dendrograph fixed to a tree

Q27 · Which combination of features is characteristic of phloem sieve tubes?

Q28 · The diagram shows two cardiac cycles of a student, with the sequence of events set…

Q29 · The following graph shows the pressure changes in the left atrium, left ventricle and…

Q30 · Which features of xerophytes reduce water loss by transpiration?

Q31 · Between 1954 and 1958 many doctors read a report that linked smoking cigarettes to deaths…

Q32 · Which component of tobacco smoke affects blood pressure?

Q33 · Which tissues are present in a bronchus?

Q34 · How would health improve if a person suffering from mild emphysema stopped smoking…

Q35 · Which disease is treated with drugs that have a similar molecular structure to DNA…

Q36 · Which factors would help prevent which disease?

Q37 · Which future development in vaccine production is most important in the fight to…

Q38 · The following statements describe some of the stages in phagocytosis

Q39 · The diagram shows some chemical conversions during the nitrogen cycle

Q40 · What is the correct match of example to ecological term?

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